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64681
Self-Assembled Peptide Hydrogels PPI45 and PPI47: Novel Drug Candidates for <i>Staphylococcus aureus</i> Infection Treatment
Published 2025-01-01“…The high-level preparation of PPI45 and PPI47 was achieved with yields of 1.82 g/L and 2.13 g/L, which are 2.19 and 2.60 times the yield of PPI42. Additionally, the critical micelle concentrations (CMCs) of the peptides at pH 7.4 for PPI42, PPI45, and PPI47 were determined to be 245 µg/mL, 973 µg/mL, and 1016 µg/mL, respectively. …”
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64682
A QUALITATIVE ANALYSIS OF THE INFLUENCE OF MANAGEMENT INFORMATION SYSTEMS ON ORGANIZATIONAL DECISION-MAKING PROCESSES
Published 2024-11-01“…A common concern expressed by participants relates to the complexity of MIS platforms and the associated learning curve that can impede initial adoption and integration. Additionally, the integrity and reliability of data generated by these systems emerged as significant challenges, with participants stressing that inaccurate or incomplete data can lead to flawed decision-making. …”
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64683
The expansion and loss of specific olfactory genes in relatives of parasitic lice, the stored-product psocids (Psocodea: Liposcelididae)
Published 2025-01-01“…These results suggest that the identification of olfactory-related genes in booklice on a genome-wide scale is more feasible and reliable than using a transcriptome-based approach. Additionally, compared to parasitic lice, booklice possess significantly more olfactory-related genes. …”
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64684
Thyroid hormone receptor- and stage-dependent transcriptome changes affect the initial period of Xenopus tropicalis tail regeneration
Published 2024-12-01“…Interestingly, ECM-receptor interaction and cytokine-cytokine receptor interaction, which are essential for blastema formation and regeneration, were significantly enriched among regulated genes in the 3 regenerative groups but not the non-regenerative group at the blastema formation period. In addition, the regulated genes specific to the nonregenerative group were highly enriched with genes involved in cellular senescence. …”
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64685
Aminoguanidine hemisulfate improves mitochondrial autophagy, oxidative stress, and muscle force in Duchenne muscular dystrophy via the AKT/FOXO1 pathway in mdx mice
Published 2025-01-01“…AGH normalized the GSSG/GSH ratio and decreased glutathione reductase and peroxidase activities, further improving redox homeostasis. Additionally, AGH reduced apoptosis, shown by fewer TUNEL-positive cells and lower caspase-3 expression. …”
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64686
Effect of Graphene Warm Abduction Orthosis on Hip Joint Development in Children with Spastic Cerebral Palsy
Published 2023-10-01“…Both groups received routine rehabilitation training. Additionally, the control group underwent adductor abduction traction training, and the treatment group wore graphene warm abduction orthosis. …”
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64687
FoxA1 knockdown promotes BMSC osteogenesis in part by activating the ERK1/2 signaling pathway and preventing ovariectomy-induced bone loss
Published 2025-02-01“…Downregulation of FOXA1 markedly augmented the expression of osteoblast-specific genes and proteins, activated the ERK1/2 signaling pathway, intensified ALP activity, and promoted mineral deposition. In addition, excessive expression of FOXA1 significantly reduced ALP activity and mineral deposits. …”
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64688
Microbial abundance and diversity in water, and immune parameters of red tilapia reared in bioflocs system with different fish density (25 fish/m3, 50 fish/m3, and 100 fish/m3)
Published 2010-07-01“…The experiment comprised of two different factors, carbon source addition (bioflocs and control), and fish stocking density (25 fish/m3, 50 fish/m3, dan 100 fish/m3), with an experimental period of 99 days. …”
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64689
HEDDI-Net: heterogeneous network embedding for drug-disease association prediction and drug repurposing, with application to Alzheimer’s disease
Published 2025-02-01“…HEDDI-Net integrates graph and shallow learning techniques to extract representative diseases and proteins, respectively. …”
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64690
Air Pollution Levels Related to Peak Expiratory Flow Rates among Adult Asthmatics in Lampang, Thailand
Published 2020-04-01“…O3 max (lag 3) and PM2.5 max exhibited positive relationships with the PEFR before sleeping (“evening PEFR”), with coefficients of 0.078 and 0.029, respectively. Additionally, the average daily PEFR was positively associated with the average daily concentration of NO2 (lag 4), with a coefficient of 0.15, but negatively associated with that of SO2, with a coefficient of −0.47. …”
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64691
Enhancing Disaster Preparedness Through Tabletop Disaster Exercises: A Scoping Review of Benefits for Health Workers and Students
Published 2025-01-01“…Etika Emaliyawati,1 Kusman Ibrahim,2 Yanny Trisyani,1 Aan Nuraeni,1 Firman Sugiharto,3 Qonita Nur Miladi,3 Hadi Abdillah,3 Mikha Christina,3 Deris Riandi Setiawan,3 Titin Sutini4 1Department of Emergency and Critical Care Nursing, Faculty of Nursing, Universitas Padjadjaran, Sumedang, West Java, Indonesia; 2Department of Medical-Surgical Nursing, Faculty of Nursing, Universitas Padjadjaran, Sumedang, West Java, Indonesia; 3Master Study Program, Faculty of Nursing, Universitas Padjadjaran, Sumedang, West Java, Indonesia; 4Department of Mental Health Nursing, Faculty of Nursing, Universitas Padjadjaran, Sumedang, West Java, IndonesiaCorrespondence: Yanny Trisyani, Faculty of Nursing, Universitas Padjadjaran, Jl. …”
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64692
MECHANISMS FOR ENSURING THE ECONOMIC DEVELOPMENT OF RURAL AREAS THROUGH THE FORMATION OF THEIR ENERGY DEPENDENCE BASED ON THE INTENSIFICATION OF BIOFUEL PRODUCTION
Published 2024-12-01“…The study examines biomass as a resource with significant potential to meet local energy needs, create additional jobs and stimulate economic growth in rural areas. …”
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64693
Estimating ocean heat content from the ocean thermal expansion parameters using satellite data
Published 2025-01-01“…These results suggest that the proposed ANN models are capable of generating satellite-based daily OHC maps by covering both shallower and deeper oceanic regions of varying bathymetry levels (<span class="inline-formula">≥20</span> m). In addition, the first-ever attempt to estimate the ocean thermal expansion component (i.e., TSL) from satellite data was successful, and the model-derived TSL can be used to obtain high-end sea level rise products in the global ocean.…”
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64694
Shock reaction model for impact energy release behavior of Al/PTFE reactive material
Published 2024-12-01“…When reactive materials are used to make warhead fragments, they can deliver a significant amount of chemical energy to the target in addition to the kinetic energy damage. When used as the core of a PELE (Penetrator with Enhanced Lateral Efficiency) projectile, reactive materials can enhance the fragmentation of the projectile shell after penetrating the target, causing both physical and chemical damage. …”
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64695
Personal, environmental and behavioral predictors associated with online fraud victimization among adults.
Published 2025-01-01“…For instance, gender- specific educational campaigns can be developed to enhance awareness and equip women with strategies to detect and avoid scams. Additionally, addressing systemic factors like social norms and digital literacy gaps is crucial for creating equitable and effective solutions to reduce online fraud victimization.…”
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64696
Hp eradication decreased the expression level of PG II in patients of Hp negative with gastric intestinal metaplasia: a retrospective cross-sectional study
Published 2025-01-01“…Among patients without Hp eradication history, those with low PG II levels had a higher proportion of individuals with a history of Hp eradication than those with high PG II levels (29.31% VS 3.13%, p = 0.003). Additionally, within the subgroup that underwent Hp eradication, there was a decrease in PG II expression level compared to the subgroup without Hp eradication (6.16(5.13, 7.52) VS 8.73(5.67, 13.35), p = 0.041). …”
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64697
Exome sequencing reveals IFT172 variants in patients with non-syndromic cholestatic liver disease.
Published 2023-01-01“…WES was used for reassessment of 34 patients (23 children) without diagnostic genotypes in ABCB11, ATP8B1, ABCB4 or JAG1 demonstrable by previous Sanger sequencing, and for primary assessment of additional 17 patients (10 children). Nasopharyngeal swab mRNA was analysed to address variant pathogenicity in two families.…”
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64698
Effects of a 16-week dance intervention on loneliness and self-esteem in left behind children: a randomised controlled trial
Published 2025-01-01“…Abstract Loneliness and low self-esteem are among the more prominent mental health problems among left-behind children, but most of the current research stays in cross-sectional surveys, with fewer studies proposing specific solutions. In addition, although the effective impact of dance interventions on loneliness and self-esteem has been demonstrated, the impact in the group of left-behind children remains under-explored. …”
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64699
Cryptocurrencies as a subject of financial fraud
Published 2022-01-01“…Therefore, there is a wide possibility of exploring not only existing but also undiscovered research trends. In addition, key types of fraud in economic practice have been identified, which is particularly important for financial market participants. …”
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64700
mHealth-Augmented Care for Reducing Depression Symptom Severity Among Patients With Chronic Pain: Exploratory, Retrospective Cohort Study
Published 2025-01-01“…Furthermore, hierarchical regression modeling revealed that patients who received mHealth-augmented psychiatric CoCM experienced the greatest sustained reductions in on-average depression severity compared with other cohorts, irrespective of clinical benchmarks. In addition, patients who engaged with an mHealth platform before entering CoCM experienced a 7.2% reduction in average depression severity before starting CoCM treatment. …”
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