Correlation of GLUT4, LEPR , and TNF-a with endometrial receptivity in women with polycystic ovarian syndrome-induced infertility by Yan Dong, Kong Wei, Yifei Li, Yan Liu, Lin Li, Yan Li

“…GLUT4, LEPR, and TNF-a levels in the peripheral blood were detected in all participants, and their diagnostic value for PCOS in healthy women and PCOS-induced infertility in PCOS patients was analyzed. In addition, the endometrial thickness and endometrial blood flow pulsation index (PI) and resistance index (RI) of patients in the research group were measured. …”
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Understanding the use of the National Early Warning Score 2 in acute care settings: a realist review protocol by Nia Roberts, Geoff Wong, Michelle Treacy, Mandy Odell

“…A systematic search will be completed, based on subject relevancy on the following databases: Cumulative Index to Nursing and Allied Health Literature (CINAHL), Medline, Embase (OvidSP), Web of Science (Science Citation Index and Social Science Citation), Cochrane Database of Systematic Reviews, Joanna Briggs Institute, Ethos, Proquest Dissertations and Theses Global, and Google Scholar for documents dating from 1997 (date of the first published EWS) to present. To retrieve additional relevant data ‘snowballing’ (finding references and authors by hand, contacting authors, searching reference lists and citation-tracking using Google Scholar) will be used. …”
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Are psychological attitudes towards vaccination an expression of personality? A cross-sectional study on COVID-19 vaccination in France by Gaëlle Lièvre, Jonathan Sicsic, Simon Galmiche, Tiffany Charmet, Arnaud Fontanet, Judith Mueller

“…The inclusion of personality traits did not substantially alter the effect estimates of the association between the 7C antecedents and vaccination behaviours, with differences between effect sizes of models with and without personality traits being < 5%. …”
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Attenuating susceptibility to ascites in cold‐stressed broiler chickens fed canola meal‐based diets by supplementing arginine or guanidinoacetic acid, either alone or in combinatio... by Negin Delfani, Mohsen Daneshyar, Parviz Farhoomand, Sina Payvastegan, Younes Ali Alijoo, Gholamreza Najafi

“…Conclusion In summary, supplementing cold‐stressed broiler chicken diets with 2.57 g/kg ARG may alleviate hypertension. Additionally, 1.8 g/kg GAA proves to be an effective substitute for dietary ARG in low‐ARG diets, alleviating adverse effects from cold stress. …”
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Elevated-temperature performance of alkali-activated nano concrete: The role of sustainable nanomaterials by R. Samuvel Raj, G. Prince Arulraj, N. Anand, Balamurali Kanagaraj, Eva Lubloy, Paul Joseph

“…An eco-friendly substitute, alkali-activated concrete (AAC), significantly lowers carbon di-oxide (CO2) emissions and energy requirements. …”
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Trace element concentrations, multivariate analysis and health risk potential of soils from urban and peri-urban agriculture by K.M. Hawrami, A.K. Baset

“…The analysis was carried out using Inductively coupled plasma mass spectrophotometry, which operated in collision cell mode with 7 percent hydrogen in helium to minimize polyatomic interferences.FINDINGS: The study findings indicated that the soils, with a potential hydrogen range of 7.5 to 8.18, are mainly calcareous and have textures that vary from silty loam to sandy or silty clay. Additionally, the organic matter content of these soils ranges from 1.4 percent to 5.47 percent. …”
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hCeO2@CA-074Me Nanoparticles Alleviate Inflammation and Improve Osteogenic Microenvironment by Regulating the CTSB-NLRP3 Signaling Pathway by Niu Z, Xia X, Zhang Z, Liu J, Li X

“…The osteogenic ability was evaluated using ALP staining, ALP quantitative analysis, alizarin red staining, and RT-PCR analysis.Results: Findings clearly demonstrated that hCeO2@CA-074Me NPs could effectively reduce the production of ROS and inhibited CTSB-NLRP3 signal pathway, thereby significantly attenuating the damage caused by the cellular inflammatory response. hCeO2@CA-074Me NPs could also induce the polarization of macrophages towards anti-inflammatory M2 phenotype. Additionally, results confirmed that hCeO2@CA-074Me NPs could inhibit inflammation and ameliorate osteogenic microenvironment, thus promoting the osteogenesis of MC3T3-E1 cells.Conclusion: The synthetic hCeO2@CA-074Me NPs could able to modify the osteogenic microenvironment under inflammatory conditions by simultaneously inhibiting the CTSB-NLRP3 signaling pathway and regulating the macrophage phenotype through their ability to scavenge ROS. …”
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Association between fibrinogen-to-albumin ratio and bone metabolism markers (β-CTX and P1NP) in Chinese individuals with osteoporotic fracture: a cross-sectional investigation by Li-long Feng, Ke Lu, Chong Li, Min-zhe Xu, Yao-wei Ye, Yi Yin, Hui-qiang Shan

“…On top of that, we used a generalized additive model (GAM) to find any non-linear correlations, and a two-piecewise linear regression model to find the threshold effects in the smoothing curves that came out of it. …”
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Food safety practice and its associated factors among food handlers working in food and drinking establishments in Hargeisa, Somaliland by Mohamed Mussa Abdilahi, Jonah Kiruja, Abdisamad Shukri Ismail, Soheir H. Ahmed, Faisal Nooh, Ayanle Suleiman Ahmed, Abdiqathar Rashid Kulmie

“…Abstract Background The World Health Organization reports that 600 million cases of food-borne illnesses occur every year. Additionally, it is estimated that upto 30% of people in developed countries experience food-borne illnesses annually, while developing countries suffer around 2 million deaths from these diseases each year. …”
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Tawaduk Santri In Nusantara Cultural Perspective: A Multi-Discourse Analysis by Khusnul Khotimah, Wevi Lutfitasari, Maulid Taembo, Mohammad Hipni

“…These practices honor Prophet Muhammad, instill noble ethics, foster Islamic brotherhood (ukhuwah islamiyah), encourage surrender to Allah, and promote restraint from worldly desires. Additionally, the pesantren cultural practices serve as environments that preserve local customs, shape students' character, foster brotherhood, offer experiential learning, impart life values, and cultivate self-restraint. …”
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Office environment and employee differences by company health management certification by Shiro Arata, Masaki Sugiuchi, Toshiharu Ikaga, Yasuyuki Shiraishi, Tatsuya Hayashi, Shintaro Ando, Shun Kawakubo

“…The results of the comparison, after controlling for covariates with propensity score matching, showed that certified health management companies tend to have employees who are more satisfied with their office environment and have a higher perceived office environment. In addition, employees in these companies were found to have better perceived outcomes. …”
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Impact of HIF-1α, LOX and ITGA5 Synergistic Interaction in the Tumor Microenvironment on Colorectal Cancer Prognosis by Hayriye Tatlı Doğan, Mehmet Doğan, Seda Kahraman, Doğukan Çanakçı, Mehmet Ali Nahit Şendur, Mustafa Tahtacı, Fazlı Erdoğan

“…Stage IV patients with the moderate to strong expression of HIF-1α, ITGA5 or LOX in the microenvironment had lower progression-free survival than those with weak expression (<i>p</i> < 0.05). In addition, female gender; moderate to strong HIF-1α, LOX and ITGA5 stromal expression; and metastatic first line chemotherapy only were found to be independently associated with an increased risk of progression. …”
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Mortality Predictors in Patients With COVID-19 Referred to the Emergency Department in Bandar Abbas, Southern Iran: A Single-Center Experience by Latife Jabbari, Leila AzizKhani, Saman Shamsipour, Saeed Hayati

“…The most important predictor of mortality was C-reactive protein (CRP) 3+, which increased the probability of mortality in COVID-19 patients by almost 25 times (odds ratio [OR]=25.338, 95% CI=1.978–324.668, P=0.013). …”
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p16 expression in patient with Loop Electrosurgical Excision Procedure (LEEP) by Putu Erika Paskarani, I Gede Sastra Winata, Elisa Laura Oktrinita Sitohang, Felyanto Felyanto, Sang Ayu Putu Yuliantini

“…Meanwhile, a statistically significant association was found between p16 expression and histopathologic diagnostic (p = 0.02, 95% CI 1.4 – 38.3). In addition, 22.2% of the variation of p16 expression based on multivariate analysis demonstrating a significant correlation (p = 0.01). …”
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Hydrolyzed Collagen from Salmon Skin Increases the Migration and Filopodia Formation of Skin Keratinocytes by Activation of FAK/Src Pathway by Wanwipha Woonnoi, Lalita Chotphruethipong, Supita Tanasawet, Soottawat Benjakul, Nuthathai Sutthiwong, Wanida Sukketsiri

“…Therefore, this study aimed to elucidate the effects of HCSS on the migration of keratinocyte HaCaT cells. Additionally, its molecular mechanism through cell division control protein 42 (Cdc42), Ras-related C3 botulinum toxin substrate 1 (Rac1), and Ras homolog family member A (RhoA) via focal adhesion kinase (FAK)-steroid receptor coactivator (Src) regulation and keratinocyte stem cells (KSCs) markers were also evaluated. …”
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Effect of Propolis on PPP2R1A and Apoptosis in Cancer Cells by Burak Durmaz, Latife Merve Oktay Çelebi, Ayşe Çekin, Ayshan Ahadova, Nur Selvi Günel, Hatice Kalkan Yıldırım, Ali Mert Özgönül, Eser Yıldırım Sözmen

“…When we compared the healthy cell lines to cancer cell lines, a statistically significant increase in caspase-3 (3.62-fold) and in TRAIL (4.38-fold) was observed in the SW-620 cell line after the application of propolis. In addition, in the PC-3 cell line, a 1.4-fold increase in caspase-8 was observed compared with the healthy cell line, which is also statistically significant. …”
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THE USE OF ZIRCONIUM CEMENTS IN MEDICINE: PHYSICO-CHEMICAL PROPERTIES AND CLINICAL BENEFITS by Giuroiu Cristian Levente, Clara Haddad, Cristina Albert, Doina Spaiuc, Rusnac Roman, Cezarina Dragomirescu, Alexandru Patrascu, Alina Stefanache

“…This research aims to examine all the physical and chemical characteristics of zirconium cements, including their structural strength, resistance to fractures, and durability against chemical degradation. Additionally, the study seeks to evaluate the medical advantages of zirconium cements, including their ability to provide long-lasting restorations, minimize problems like microleakage, and ensure a natural appearance that closely mimics the visual characteristics of tooth enamel. …”
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Alu insertion polymorphisms and susceptibility to metabolic syndrome in a Moroccan population by Hamid Farhane, Majida Motrane, Karchali Soufaine, Fatima-Ezzahra Anaibar, Aïcha Motrane, Said Nassor Abeid, Abderraouf Hilali, Nourdin Harich

“…Additionally, a significant association was revealed with MetS in men carrying the *Ins allele and the Alu-TPA25 II genotype (OR = 2.11, 95% CI [1.00–4.44], p = 0.0487). …”
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miR-16-5p aggravates sepsis-associated acute kidney injury by inducing apoptosis by Han Li, Junyan Duan, Tongtong Zhang, Yingjie Fu, Yue Xu, Hongjun Miao, Xuhua Ge

“…In vitro, the expression level of miR-16-5p in HK-2 cells treated with 10 μg/mL lipopolysaccharide (LPS) increased by more than 2 times. In addition, LPS-exposed renal tissue and HK-2 cells lead to upregulation of inflammatory cytokines IL-6, IL-1β, TNF-a, and kidney damage molecules kidney injury molecule-1 (KIM-1), neutrophil gelatinase-associated lipocalin (NGAL). …”
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Unveiling the ultimate advantage: a meta-analysis of 3D visualization and problem-based learning in orthopedic education by Ting Li, Yidan Hu, Ruohong Song, Hangyu Liu, Xin Gao, Fei Wang, Chengwei Xiao, Xilin Liu

“…Furthermore, students exposed to 3D + PBL teaching exhibited a significantly better understanding of orthopedic anatomical structures compared to those receiving LBL (SMD = 1.18, 95% CI: 0.71–1.65, P < 0.00001). Additionally, students in the 3D + PBL group achieved higher theoretical grades (OR = 2.95, 95% CI: 1.57–5.55, P = 0.0008) and reported greater overall satisfaction (OR = 3.26, 95% CI: 1.91–5.54, P < 0.0001) compared to their LBL counterparts. …”
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