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64441
Novel Trade-offs in 5 nm FinFET SRAM Arrays at Extremely Low Temperatures
Published 2025-01-01“…With the help of SRAM array simulations, we reveal that the maximum array size at extremely low temperatures is limited by WL parasitics instead of <inline-formula><tex-math notation="LaTeX">$I$</tex-math></inline-formula><sub>leak</sub>, and the performance of the SRAM is governed by BL and WL parasitics. In addition, we elucidate the influence of transistor threshold voltage (<inline-formula><tex-math notation="LaTeX">$V$</tex-math></inline-formula><sub>TH</sub>) engineering on the optimization of the SRAM array at extremely low temperature environments.…”
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64442
Association between red cell distribution width—albumin ratio and all-cause mortality in intensive care unit patients with heart failure
Published 2025-01-01“…The time-concordance index curve was carried out to explore the additional prognostic value of RAR on mortality over the existing scoring systems, Serial Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation Ⅱ (APACHE Ⅱ).ResultsThe analysis encompassed a cohort of 4,506 patients, with Kaplan-Meier curves indicating that individuals with higher RAR levels exhibited an elevated risk of all-cause mortality (p < 0.001). …”
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64443
Microplastics: A threat to Fetoplacental unit and Reproductive systems
Published 2025-06-01“…They also bioaccumulate in testes, altering spermatogenesis, spermatozoa morphology, testosterone production, body weights, and inflammation as reported in mice. …”
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64444
Drug-induced autoimmune-like hepatitis: A disproportionality analysis based on the FAERS database.
Published 2025-01-01“…Among these, nitrofurantoin (ROR 94.79, CI 78.53-114.41), minocycline (ROR 77.82, CI 65.09-93.05), and nivolumab (ROR 47.12, CI 15.06-147.39) exhibited the strongest signals. Additionally, several previously unreported drugs, including mesalazine, aldesleukin, onasemnogene abeparvovec-xioi, and nefazodone, were identified as having strong associations with DI-ALH. …”
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64445
Impact of geochemical reactivity on desulphation requirements in a sandstone reservoir containing carbonate and sulphate minerals
Published 2025-01-01“…In this study, as preparation for addition of geochemistry to a full field 3D history matched model, we include geochemical reactions in a 1D model that has the field pressure, temperature and fluid properties, to test the impact of the various potential reactions in a simple system. …”
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64446
Pharmacists’ perceptions of the new pharmaceutical vaccination service in Romania: a comprehensive first two-years evaluation
Published 2025-01-01“…The majority (82%) felt that their salaries should be increased related to the vaccination service. Additionally, there is a need for improvements in the pharmacy schedule and the advance scheduling of vaccinations.ConclusionThis study was developed to assist future health policies through expansion of advanced pharmaceutical services, and adding other vaccines to community pharmacy portfolios.…”
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64447
The adaptation process of a safety planning intervention to promote connectedness and reduce distress in Diné adolescents and adults during the COVID-19 pandemic
Published 2025-01-01“…Most importantly, this CAB collaborative with researchers to further tailor safety plan intervention materials to align with Navajo values related to connectedness to relatives, community, mental health resources, and the land. In addition, the caring contacts messaging was aligned with safety plans to provide culturally sensitive messages that would be shared with randomized participants.DiscussionMental health stigma is highly common in reservation-based communities. …”
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64448
Maternal milk fat globule membrane enriched gut L. murinus and circulating SCFAs to improve placental efficiency and fetal development in intrauterine growth restricted mice model
Published 2025-12-01“…Meanwhile, MFGM supplementation during gestation enriched intestinal Lactobacillus murinus (L. murinus) and increased luminal and circulating short chain fatty acids (SCFAs) in IUGR pregnant mice, which improved placental efficiency and fetal development due to an enhanced antioxidant capacity and a decreased inflammation. In addition, fecal microbiota transplantation (FMT) with MFGM-derived microbiota reprinted the promoted phenotypes of maternal litter characteristics, gut L. murinus enrichment, placental efficiency, and fetal gut development in MFGM-fed pregnant mice, which were also recapitulated by exogenous administration with L. murinus or SCFAs cocktail. …”
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64449
The Impact of Dermal Characteristics on Low-Level Laser Power Measurement in Postmortem Zoological Species
Published 2024-01-01“…Darker pigmented areas of tissue appeared to absorb the laser light, which also did not allow light passage through the tissue to the photo meter. …”
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64450
Characterisation of cardiovascular disease (CVD) incidence and machine learning risk prediction in middle-aged and elderly populations: data from the China health and retirement lo...
Published 2025-02-01“…Although the LGB model achieves an AUC of 0.818, indicating strong overall performance, its F1 score and recall rate are relatively low, at 0.509 and 43.1%, respectively. Shapley additive explanations (SHAP) analyses revealed the importance of key features, such as night sleep duration, TG levels, and waist circumference, in predicting outcomes, and highlighted the nonlinear relationships between these features and CVD risk. …”
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64451
IOP-lowering therapy and ocular surface in glaucoma. Part 1. The effects of drug substances of glaucoma medications on the ocular surface
Published 2020-06-01“…Dose- and exposition-dependent loss of goblet cells, corneal epithelial toxicity, meibomian gland dysfunction, increased activity and expansion of fibroblasts, and pro-inflammatory cytokine release from goblet cells account for the development and progression of symptoms and signs of dry eye as demonstrated by progressive deterioration in Ocular Surface Disease Index (OSDI), Norn’s test, and Schirmer’s test. …”
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64452
Effect of trace elements and nutrients on 21 autoimmune diseases: a Mendelian randomization study
Published 2025-01-01“…Finally, trace elements and vitamins that were statistically significant in the IVW method and had consistent effect sizes and odds ratios across five methods were selected as exposure factors with a causal relationship to diabetes and its complications. …”
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64453
A retrospective cohort study: do patients with graves’ disease need to be euthyroid prior to surgery?
Published 2018-05-01“…Conclusions In our study, biochemically hyperthyroid patients undergoing thyroidectomy did not develop thyroid storm. Additional studies with larger sample sizes are needed to better understand the risk of thyroid storm in hyperthyroid patients.…”
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64454
Metabolic redundancy and specialisation of novel sulfide-oxidizing Sulfurimonas and Sulfurovum along the brine-seawater interface of the Kebrit Deep
Published 2025-02-01“…Their energy generation processes include aerobic or anaerobic-nitrate-dependent sulfide oxidation, as well as hydrogen oxidation. In addition to the osmoprotectant pathways commonly observed in Campylobacterota, such as the synthesis and uptake of proline and glutamate, the two Kebrit Deep Sulfurovum species exhibit genomic signatures for ectoine synthesis, further aiding their adaptation to high salinity. …”
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64455
Tilrettelegging på eksamen for studenter med funksjonsnedsettelser
Published 2024-12-01“…Key findings include a high degree of variation in information about accommodations regarding exams on the institutions’ websites. In addition, there is less correspondence between available information and the accommodations that the students describe as having received. …”
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64456
Assessing Health Disparities in Digital Services and Technologies During and After the COVID-19 Pandemic: A Pooled Cross-Sectional Analysis Using HINTS Data
Published 2025-01-01“…Portal usage is positively correlated with health app use, urbanity, higher income, sex, Asian/Native American race/ethnicity, and hospital trust. In addition, our data shows low adoption rates across the digital divide. …”
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64457
Investigation of the Influence of Deletional and Non-Deletional Hemoglobin H Disease on Pregnancy Outcomes
Published 2025-01-01“…Moreover, the deletional group exhibited a significantly lower mean corpuscular volume (MCV) during early and late pregnancy and mean corpuscular hemoglobin (MCH) during late pregnancy, with statistically significant differences (p< 0.05) compared to the non-deletional group. Additionally, the non-deletional group had a significantly higher incidence of postpartum blood transfusion, fetal growth restriction (FGR), and low birth weight (LBW) compared to the deletional group, with a statistically significant difference (p< 0.05).Conclusion: Pregnant patients with alpha-thalassemia HbH disease and non-deletional HbH disease commonly experience moderate anemia, increasing the risk of adverse pregnancy outcomes, particularly in non-deletional HbH disease cases where negative outcomes are more prevalent. …”
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64458
What Affects Agricultural Green Total Factor Productivity in China? A Configurational Perspective Based on Dynamic Fuzzy-Set Qualitative Comparative Analysis
Published 2025-01-01“…There was a significant upward trend in AGTFP across China, indicating notable progress in green agricultural development. Additionally, three pathways promoting AGTFP improvement were identified: resource–economy-driven, technology–policy-guided, and multifactor-synergy. …”
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64459
Evaluation of 902 Total Abdominal Hysterectomies Performed for Benign Reasons
Published 2014-08-01“…In 119 patients (13.2%) an additional surgical intervention was applied during operation. …”
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64460
Systemic Immune-inflammation Index in Evaluation of Inflammation in Rheumatoid Arthritis Patients
Published 2024-09-01“…Patients with RA who had hs-CRP levels of 3 mg/L above exhibited a statistically significant increase in the SII compared with those with hs-CRP levels below 3 mg/L. Additionally, within the cohort of RA patients with hs-CRP levels at or above 3 mg/L, a positive correlation was found between the SII index and both NLR and PLR. …”
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