Antimicrobial Residues in Poultry Litter: Assessing the Association of Antimicrobial Persistence with Resistant <i>Escherichia coli</i> Strains by Paula Cortés, Ekaterina Pokrant, Karina Yévenes, Aldo Maddaleno, Andrés Flores, María Belén Vargas, Lina Trincado, Matías Maturana, Lisette Lapierre, Javiera Cornejo

“…<b>Methods</b>: Forty broiler chickens were raised under controlled conditions and divided into three experimental groups, each treated with a different antimicrobial, in addition to an untreated/control group. Litter samples were collected post treatment, analyzed by UPLC-MS/MS, and processed for the isolation of <i>E. coli</i>. …”
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Therapeutic benefit of the dual ALK/FAK inhibitor ESK440 in ALK-driven neuroblastoma by Seema Chugh, Jean C. Tien, Jennifer Hon, Carson Kenum, Rahul Mannan, Yunhui Cheng, Chi Chiang Li, Zainab I. Taher, Andrew D. Delekta, Pushpinder Singh Bawa, Ingrid J. Apel, Stephanie J. Miner, Xuhong Cao, Rohit Mehra, Saravana M. Dhanasekaran, Yuanyuan Qiao, Rajen Mody, Arul M. Chinnaiyan

“…Genomic studies have identified common driver aberrations in high-risk NB, such as MYCN amplification. In addition, a proportion of high-risk patients harbor amplification or activating mutations in anaplastic lymphoma kinase (ALK), and co-occurrence of ALK mutations and MYCN amplification have been associated with aggressive disease. …”
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Effects of Standardized Natural Citrus Extract on Growth, Gut Health, Carcass Quality, and Welfare of Broiler Chickens by Sekhou Cisse, Arkadiusz Matuszewski, Damian Bień, Patrycja Ciborowska, Anna Zalewska, Jakub Urban, Monika Michalczuk, Marta Mendel, Urszula Latek, Joanna Polak, Małgorzata Sobczak-Filipiak, Paweł Konieczka, Mohammed El Amine Benarbia

“…The carcass weight was also significantly higher in the SNCE group. In addition, the fat percentage was lower in the SNCE group. …”
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The correlation and predictive value of Hb, RDW and their association for short-term and long-term mortality in patients with acute aortic dissection by Peng Hou, Peng Hou, Lin Xia, Fangran Xin, Boxuan Sun, Guoxin Zhang, Liming Yu, Huishan Wang

“…Using adjusted Cox regression and Kaplan-Meier survival curve analyses, we assessed the relationship between Hb, RDW and their association at admission and mortality at multiple post-discharge intervals (30 days, 90 days, 1 year, and 5 years) among patients with AAD. Additionally, subgroup analyses and receiver operating characteristic (ROC) curve analyses were conducted to evaluate the predictive accuracy of Hb, RDW and their association for mortality in this patient population.ResultsHigh RDW combined with low Hb (RDW ≥ 13.60 and Hb &lt; 7.9) significantly predicted increased mortality at 30 days, 90 days, 1 year, and 5 years post-diagnosis, with hazard ratios (HRs) as follows: 4.33 (95% CI: 1.82–10.33, P &lt; 0.001), 4.48 (95% CI: 2.06–9.77, P &lt; 0.001), 3.38 (95% CI: 1.70–6.70, P &lt; 0.001), and 3.07 (95% CI: 1.66–5.66, P &lt; 0.001), respectively.ConclusionHb and RDW are both abnormal (Hb with low level, RDW with high level) is positively correlated with 30 days, 90 days, 1 year, and 5 years mortality risk in patients with AAD. …”
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Genomic insights on cgMLST markers, drug resistance, and urease cluster of Proteus mirabilis strains by Shitao Lian, Yadong Liu, Songnian Hu, Chen Shen, Yinping Ma, Peng Yin, Zilong He

“…The objective was to elucidate the pan-genomic structure of P. mirabilis, revealing the composition and distribution of core and accessory gene families among different strains. Additionally, an attempt was made to construct a core genome multilocus sequence typing scheme specific to this species in order to enhance the precision of describing genetic diversity and evolutionary relationships. …”
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Validation of the efficacy of the porous medium model in hemodynamic analysis of iliac vein compression syndrome by Lingling Wei, Ke Hu, Jiaqiu Wang, Shuang Zhang, Xiaoxiao Yang, Yuanli Chen, Chenshu Li, Xinwu Lu, Kaichuang Ye, Peng Qiu, Yanqing Zhan, Yanqing Zhan

“…Additionally, the concentration variation curve of discrete phase particles demonstrated a high concordance rate of 92.4% compared to that obtained in DSA. …”
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Beneficial Effect of Multidomain Cognitive Training on the Neuropsychological Performance of Patients with Early-Stage Alzheimer’s Disease by Anastasia Nousia, Vasileios Siokas, Eleni Aretouli, Lambros Messinis, Athina-Maria Aloizou, Maria Martzoukou, Maria Karala, Charalampos Koumpoulis, Grigorios Nasios, Efthimios Dardiotis

“…Considering the limited efficacy of current pharmacological therapies in AD, concurrent computer-based MCT may represent an additional enhancing treatment option in early-stage AD patients.…”
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Advancements and challenges in agriculture: a comprehensive review of machine learning and IoT applications in vertical farming and controlled environment agriculture by Binoy Sasmal, Gobinda Das, Preeti Mallick, Sneha Dey, Suman Ghorai, Subrata Jana, Chiranjibe Jana

“…According to the research, to feed 8 billion people, we would need an additional 109 hectares of land. That is the typical problem that the farmers will face because most of the hollandaise nowadays. …”
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Genetic variations and clinical significance in young-onset nasopharyngeal cancer: Analysis of EBV interaction with cellular receptor variants and viral glycoproteins by Sulistyo Emantoko Dwi Putra, Farizky Martriano Humardani, Hikmawan Wahyu Sulistomo, Yulanda Antonius, Jonathan Jonathan, Riyan Charlie Milyantono, Artika Uthary, Risma Ikawaty

“…This finding implies that the p.Val179Ala variant in subject one could obstruct EBV entry, possibly leading to less severe clinical symptoms Our research provides new insights into the genetic factors influencing the clinical presentation of NPC, identifying promising targets for further research and therapeutic interventions. However, additional validation in a larger cohort is required to elucidate the broader impact of these genetic variants.…”
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MR Imaging of Prostate Cancer: Diffusion Weighted Imaging and (3D) Hydrogen 1 (1H) MR Spectroscopy in Comparison with Histology by J. Yamamura, G. Salomon, R. Buchert, A. Hohenstein, J. Graessner, H. Huland, M. Graefen, G. Adam, U. Wedegaetner

“…The results of our study showed that both DWI and MRS should be considered as an additional and complementary tool to the T2-weighted MRI for detecting prostate cancer.…”
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Waste ceramic powder for sustainable concrete production as supplementary cementitious material by Yasin Onuralp Özkılıç, Yasin Onuralp Özkılıç, Alireza Bahrami, Yusuf Güzel, Ali Sinan Soğancı, Memduh Karalar, Essam Althaqafi, Ali İhsan Çelik, Özer Zeybek, P. Jagadesh

“…Furthermore, taking into account our experimental research and previous studies on concrete produced utilizing WCP, straightforward equations were provided for practical use to predict CS, STS, and FS. In addition, scanning electron microscopy was done to validate the findings obtained from the experimental part of the study. …”
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CoronaVac-induced antibodies that facilitate Fc-mediated neutrophil phagocytosis track with COVID-19 disease resolution by Chuang Li, Jie Yu, Rahma Issa, Lili Wang, Mingzhe Ning, Shengxia Yin, Jie Li, Chao Wu, Yuxin Chen

“…Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants raise concerns about decreased vaccine efficacy, vaccines continue to confer robust protection in humans, implying that immunity beyond neutralization contributes to vaccine efficacy. In addition to neutralization, antibodies can mediate various Fc-dependent effector functions, including antibody-dependent cellular phagocytosis (ADCP), antibody-dependent neutrophil phagocytosis (ADNP) and antibody-dependent cellular cytotoxicity (ADCC). …”
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Alleviating heat stress on broiler breeder hens: Effect of dietary antioxidant supplementation on reproductive performance, egg quality, offspring growth, and antioxidant capacity by Phocharapon Pasri, Chayanan Pukkung, Pascal Mermillod, Nadine Gérard, Orapin Jantasaeng, Merisa Sirisopapong, Supattra Okrathok, Thanatat Thiabching, Sitthipong Rakngam, Kanokwan Kamkajon, Yongcai Zhu, Sutisa Khempaka

“…Although the body weight of offspring from either antioxidant source was initially low on day 1, it subsequently increased until reaching levels comparable to those in the TN and HS without supplementation by 3 weeks of age (P > 0.05). …”
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Functional connectivity within sensorimotor cortical and striatal regions is regulated by sepsis in a sex-dependent manner by Quan Vo, Zachary D. Simon, Gwoncheol Park, Dina C Nacionales, Carmelina Gorski, Evan L Barrios, Gemma Casadesus, Philip A Efron, Lyle L Moldawer, Ravinder Nagpal, Paramita Chakrabarty, Marcelo Febo

“…Following sepsis, both male and female mice survived the procedure, regained body weight within 7 days post-sepsis and showed reduced diversity in their gut microbiome. …”
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Codon usage patterns and genomic variation analysis of chloroplast genomes provides new insights into the evolution of Aroideae by Xinbi Jia, Jiaqi Wei, Yuewen Chen, Chenghong Zeng, Chan Deng, Pengchen Zeng, Yufei Tang, Qinghong Zhou, Yingjin Huang, Qianglong Zhu

“…Thirteen to twenty optimal codons ending in A/T were identified in 61 Aroideae species. Additionally, the comparative analysis of CPGs revealed that two single copy regions and non-coding regions were variable in Aroideae. …”
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Association between Atopic Dermatitis and Dementia: Evidence from Systematic Review, Meta-analysis, and Mendelian Randomization by Yeon-Su Gwak, Seo-Yeon Kim, Chae-Eon Woo, Kihyuk Shin, Eunjeong Son, Jin-Woo Kim, Sung-Jin Kim, Tae-Jin Song, Hae Ryoun Park, Kihun Kim, Dai Sik Ko, Yun Hak Kim

“…While the meta-analysis revealed a significant association, MR analysis did not substantiate a significant causal link. …”
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Mineralocorticoid axis activity and cardiac remodeling in patients with ACTH-dependent Cushing’s syndrome by Peter Wolf, Simon Travers, Oliver Domenig, Stephanie Baron, Anne Blanchard, Khaoula Bouazizi, Nadjia Kachenoura, Sylvie Salenave, Marko Poglitsch, Alban Redheuil, Severine Trabado, Jacques Young, Philippe Chanson, Peter Kamenický

“…Changes in the renin–angiotensin system and in the mineralocorticoid axis activity could be involved as potential mechanisms in their pathogenesis, in addition to cortisol excess. Methods: In this ancillary study of our previous study prospectively investigating patients with ACTH-dependent Cushing’s syndrome by cardiac magnetic resonance imaging (NCT02202902), 11 patients without any interfering medication were cross-sectionally compared to 20 control subjects matched for age, sex and body mass index. …”
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Identifying biomarkers for epilepsy after cerebral malaria in Zambian children: rationale and design of a prospective observational study by Bo Zhang, Archana A Patel, Gretchen L Birbeck, Maitreyi Mazumdar, Suzanna Mwanza, Rosemary Nyirongo, Dixon Berejena, Joseph Kasolo, Tina Mwale, Violet Nambeye, Kafula Lisa Nkole, Nfwama Kawatu, Alexander Rotenberg

“…We propose to study the sensitivity of quantitative and qualitative EEG metrics in predicting PME, and the potential increased sensitivity of this measure with additional clinical metrics. Our goal is to develop a predictive PME index composed of EEG and clinical history metrics that are highly feasible to obtain in low-resourced regions.Methods and analyses This prospective observational study being conducted in Eastern Zambia will recruit 250 children aged 6 months to 11 years presenting with acute CM and follow them for two years. …”
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Angiopoietin-2 and D-dimer add prognostic information to clinical risk in pulmonary arterial hypertension by Heather L. Clark, Daniel Lachant, Allison N. Light, Deborah Haight, Samia Lopia, Nigel Mackman, R. James White

“…Conclusions: Angiopoietin-2 and D-dimer are elevated in patients with PAH and may add prognostic information to routine clinical assessment.…”
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Targeting Cutaneous Leishmaniasis with Thiadiazine Thione Derivatives: An In Vivo Study of Its Anti-Inflammatory, Anti-Pyretic, Anti-Nociceptive, and Anti-Sedative Properties by Sarah Sarwar, Nadia Sarwar, Haleema Ali, Rafiullah, Rasool Khan, Ajaz Ahmad, Amin Ullah, Ho Soonmin, Nazif Ullah

“…In the antipyretic assay, C1 and C5 were able to reduce body temperature to a normal level within 1 h of treatment. …”
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