Loss of phosphatase and tensin homolog (PTEN) increases Lysyl oxidase-like 2 (LOXL2) expression enhancing the growth of fallopian tube epithelial cells as three-dimensional spheroi... by Angela Russo, Junlone Moy, Manead Khin, Timothy R. Dorsey, Alfredo Lopez Carrero, Joanna E. Burdette

“…Results: We found that a reduction in LOXL2 expression did not significantly change the migration or invasive capabilities of PTEN-depleted MOE or human ovarian cancer cells. …”
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Effect of Buffer Charge Redistribution on RF Losses and Harmonic Distortion in GaN-on-Si Substrates by Pieter Cardinael, Sachin Yadav, Bertrand Parvais, Jean-Pierre Raskin

“…In this paper, we show that up to 50&#x0025; variation in <inline-formula> <tex-math notation="LaTeX">${\rho }_{eff}$ </tex-math></inline-formula> at 2 GHz can take place over more than 1,000 s when the substrate is stressed at 50 V. Additionally, Coplanar Wave Guide (CPW) large-signal measurements under the same experimental conditions show a variation of <inline-formula> <tex-math notation="LaTeX">$2^{\mathrm{ nd}}$ </tex-math></inline-formula> harmonic power of up to 5dB. …”
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Combined surgical and interventional cardiology approach for central venous access salvage in children with intestinal failure: A case series by Emily Byrd, M. Jake Petersen, Minna M. Wieck, Frank Ing, Shinjiro Hirose

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Influence of alcohol blend fuels on performance and noise emission in spark ignition engine by Ali Murtaza Ansari, Liaquat Ali Memon, Faheem Ahmed Solangi, Mamdouh T. Ghannam, Mohamed Y.E. Selim

“…The findings demonstrated increases in ethanol content, power, thermal efficiency, and brake specific fuel consumption as the concentration increased. Additionally, adding ethanol reduces toxic exhaust particles. …”
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Discovery and characterization of complete genomes of 38 head-tailed proviruses in four predominant phyla of archaea by Tianqi Xu, Yimin Ni, Hailing Li, Shuang Wu, Shuling Yan, Lanming Chen, Yongxin Yu, Yongjie Wang

“…ABSTRACT Archaea play a significant role in natural ecosystems and the human body. Archaeal viruses exert a considerable influence on the structure and composition of archaeal communities and their associated ecological environments. …”
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Frequency and risk factors of retinopathy of prematurity: a 5-year single-center study in a Tertiary Care Hospital by Maaly Abdel Fattah, Anas AlKhabaz, Ibrahim Issa, Hadeel Alhemsi, Kassem AlSaad, Eyad AlMidani, Faisal Khan

“…Aim Our study aimed to determine the frequency of retinopathy of prematurity (ROP) in a cohort of premature infants screened for ROP, to confirm the efficacy of our screening program used in the NICU to avoid childhood blindness. In addition, we aimed to study the associated risk factors affecting ocular status including birth weight (BW), gestational age (GA), mechanical ventilation, length of intensive care unit (ICU) stay, and number of ROP follow-up. …”
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Genetic classification and geochemical evaluation of Upper Cretaceous carbonate reservoir oils in Dezful Embayment and Abadan Plain, SW Iran by Hossein Saadati, Ali Kadkhodaie, Mehrab Rashidi, Hossein Bahrami, Hashem Sarafdokht, Dmitriy A. Martyushev, Amir Abbass Jahangard

“…The Garau Formation was identified as the main candidate source rock, with the Sargelu and Kazhdumi Formations playing secondary roles to some extent in the generation of Family A oils. Additionally, the study underscored the impact of source rock maturity, organofacies, and trap formation timing as crucial factors influencing the geochemical characteristics of these reservoir oils across the studied area.…”
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Predicting the Progress of Tuberculosis by Inflammatory Response-Related Genes Based on Multiple Machine Learning Comprehensive Analysis by Shuai Ma, Peifei Peng, Zhihao Duan, Yifeng Fan, Xinzhi Li

“…These genes were then used to develop diagnostic nomograms. In addition, single-cell expression clustering analysis, immune cell expression clustering analysis, GSVA analysis, immune cell correlation, and immune checkpoint correlation of characteristic genes were conducted. …”
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Using diagnostic data from veterinary diagnostic laboratories to unravel macroepidemiological aspects of porcine circoviruses 2 and 3 in the United States from 2002-2023. by Guilherme Cezar, Edison Magalhães, Kinath Rupasinghe, Srijita Chandra, Gustavo Silva, Marcelo Almeida, Bret Crim, Eric Burrough, Phillip Gauger, Christopher Siepker, Marta Mainenti, Michael Zeller, Eduardo Fano, Pablo Piñeyro, Rodger Main, Mary Thurn, Paulo Lages, Cesar Corzo, Albert Rovira, Hemant Naikare, Rob McGaughey, Franco Matias-Ferreyra, Jamie Retallick, Jordan Gebhardt, Jon Greseth, Darren Kersey, Travis Clement, Angela Pillatzki, Jane Christopher-Hennings, Melanie Prarat, Ashley Johnson, Dennis Summers, Craig Bowen, Joseph Boyle, Kenitra Hendrix, Andreia G Arruda, Daniel Linhares, Giovani Trevisan

“…PCV3 detection was more frequent in adult/sow farms, while PCV2 was more frequently detected in the wean-to-market category. An additional analysis used results from tissue diagnostic data from 2019-2023 from one VDL to associate PCR cycle threshold (Ct) values with the probability of confirming a PCV2 or PCV3 disease diagnosis confirmation. …”
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Antimicrobial use in animal farms in Egypt: rates, patterns, and determinants by Nada ElSayed, Amira Amine, Laila El-Attar, Mohamed E. K. Amin

“…An online search was conducted to identify additional farms not included in the list or when the contact information was unavailable. …”
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Immunomodulatory effects of thymol and cinnamaldehyde in chicken cell lines by C. Shen, L.G. Christensen, S.Y. Bak, N. Christensen, K. Kragh

“…Thymol and cinnamaldehyde are phytogenic feed additives that have been developed to improve gut health, immunity and growth performance in poultry and swine. …”
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A Novel Tool for High-Throughput Screening of Granulocyte-Specific Antibodies Using the Automated Flow Cytometric Granulocyte Immunofluorescence Test (Flow-GIFT) by Xuan Duc Nguyen, Thomas Dengler, Monika Schulz-Linkholt, Harald Klüter

“…As positive controls, 12 sera with known antibodies against anti-HNA-1a, -b, -2a; and -3a were additionally investigated. Whole-blood samples from HNA-typed donors were collected and the test cells isolated using cell sedimentation in a Ficoll density gradient. …”
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Effect of Acupuncture Combined with Enriched Rehabilitation Training on Neural Function, Nogo Protein and Its Receptor in Cerebral Ischemia Rats by Mengxing LI, Zhaohui CHEN, Qi LIU, Fang LIU, Wei TANG

“…The expression of Nogo-A and NgR proteins in the model group, the acupuncture group, the enriched rehabilitation training group and the acupuncture combined with enriched rehabilitation training group were higher respectively than those of the sham operation group (<italic>P</italic>&lt;0.01 or <italic>P</italic>&lt;0.05), the proteins expression in the acupuncture group, the enriched rehabilitation training group and the acupuncture combined with enriched rehabilitation training group were lower respectively than those of the model group (<italic>P</italic>&lt;0.01 or <italic>P</italic>&lt;0.05), and the proteins expression in the acupuncture combined with enriched rehabilitation training group were lower respectively than those of the acupuncture group and the enriched rehabilitation training group (<italic>P</italic>&lt;0.01 or <italic>P</italic>&lt;0.05).Conclusion:Acupuncture combined with enriched rehabilitation training can improve hippocampal pathological damage induced by cerebral ischemia, and promote the recovery of sensory and motor functions. Additionally, the effect of acupuncture combined with enriched rehabilitation training is superior to that of simple acupuncture or simple rehabilitation training.…”
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Single-cell RNA-seq analysis reveals microenvironmental infiltration of myeloid cells and pancreatic prognostic markers in PDAC by Yanying Fan, Lili Wu, Xinyu Qiu, Han Shi, Longhang Wu, Juan Lin, Jie Lin, Tianhong Teng

“…Results Using the scRNA-seq dataset, we identified 7 clusters of myeloid cells, and these clusters were assigned a cell type based on their marker genes. In addition, the results of the CellChat analysis and SCENIC analysis indicate that TAM-spp1 cells may promote the migration of pancreatic tumor cells on different levels. …”
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Constraints of S–Pb–Sr Isotope Compositions and Rb–Sr Isotopic Age on the Origin of the Laoyingqing Noncarbonate-Hosted Pb–Zn Deposit in the Kunyang Group, SW China by Hongsheng Gong, Runsheng Han, Peng Wu, Gang Chen, Lingjie Li

“…Second, the Pb isotopic compositions of sulfides show a linear trend on the average crustal Pb evolution curve in 207Pb/204Pb vs. 206Pb/204Pb plot. In addition, Pb isotopic ratios were consistent with the age-corrected Pb isotopic ratios of basement rocks, consequently suggesting that the source of mixed crustal Pb is mainly derived from basement rocks. …”
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Diabetes control in public assistance recipients and free/low-cost medical care program beneficiaries in Japan: a retrospective cross-sectional study by Daisuke Nishioka, Mitsuhiko Funakoshi, Seiji Haruguchi, Sakae Yonemura, Takashi Takebe, Misato Nonaka, Sanae Iwashita

“…Among patients aged ˂65 years with HbA1c levels above 7%, the adjusted OR was significantly higher in FLCMC programme beneficiaries (OR=3.82, 95% CI: 1.65 to 10.43) than in PHI-only beneficiaries. Additionally, the adjusted OR was significantly higher in FLCMC programme beneficiaries aged ˂65 years (OR=2.57, 95% CI: 1.02 to 7.44) than in PARs.Conclusions This study highlights the predictive value of public assistance or the FLCMC programme for poor blood glucose control and suggests the inadequacy of current medical expense subsidies to eliminate health disparities in diabetes control.…”
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Asymptomatic malaria parasitaemia and seizure control in children with nodding syndrome; a cross-sectional study by Charles R J C Newton, Albert Ningwa, Kevin Marsh, Richard Idro, Rodney Ogwang, Ronald Anguzu, Pamela Akun, Edward Kayongo

“…The number of seizures in asymptomatic persons was 3.0 (IQR 2.0–7.3) and 6.0 (IQR 4.0–10.0) in symptomatic individuals, p=0.024. Additionally, in asymptomatic patients, a positive correlation was observed between the parasite density and number of seizures, r=0.33, p=0.002.Conclusion In patients with nodding syndrome, both asymptomatic and symptomatic malaria are associated with an increased risk of seizures and poorer seizure control. …”
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The novel CD16A/anti-CD3 bifunctional protein, eCD16A/anti-CD3-BFP, redirects T cell cytotoxicity toward antibody-bound target cells by Chien-Ting Lin, Shang-Ju Wu, Cheng Hao Liao, Reyhung Roc Weng, Chun-Ming Lin

“…In an ex vivo assay, eCD16A/anti-CD3-BFP combined with rituximab effectively eliminated B cells within peripheral blood samples from healthy donors and cancer patients; the effectiveness of this treatment was further enhanced by addition of either autologous or allogeneic γ9δ2 T cells. …”
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Quick sequential organ failure assessment score combined with other sepsis-related risk factors to predict in-hospital mortality: Post-hoc analysis of prospective multicenter study... by Ryo Ueno, Takateru Masubuchi, Atsushi Shiraishi, Satoshi Gando, Toshikazu Abe, Shigeki Kushimoto, Toshihiko Mayumi, Seitaro Fujishima, Akiyoshi Hagiwara, Toru Hifumi, Akira Endo, Takayuki Komatsu, Joji Kotani, Kohji Okamoto, Junichi Sasaki, Yasukazu Shiino, Yutaka Umemura

“…The AUC for predicting in-hospital mortality was 0.627 (95% confidence interval [CI]: 0.580-0.673) for the qSOFA-Only model. Addition of other variables only marginally improved the model's AUC; the model that included all potentially relevant variables yielded an AUC of only 0.730 (95% CI: 0.687-0.774). …”
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Img2Vocab: Explore Words Tied to Your Life With LLMs and Social Media Images by Kanta Yamaoka, Ko Watanabe, Koichi Kise, Andreas Dengel, Shoya Ishimaru

“…While our system prioritizes user privacy with opt-in data control and secure design, we explore additional ethical considerations. This paves the way for a future where personalized language learning, grounded in real-world experiences and generative AI, benefits learners.…”
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