Factors Associated with the Severity of Stress Urinary Incontinence in Elderly Women by Suting Li, Zhi Wang, Lian Yang, Shaoying Liu, Lili Jing, Li Hong

“…Results: Univariate analysis revealed that a history of postpartum urinary incontinence and chronic constipation significantly influenced the severity of SUI symptoms in the elderly (p < 0.05). Additionally, age, the number of vaginal deliveries, and a history of chronic cough were correlated with the severity of SUI symptoms, with p-values of 0.05, 0.08, and 0.12, respectively. …”
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Single-cell transcriptomics analysis reveals dynamic changes and prognostic signature in tumor microenvironment of PDAC by Yongsheng Li, Zhilong Ding, Tingxin Cheng, Yihuai Hu, Fei Zhong, Shiying Ren, Shiyan Wang

“…We defined a novel Treg and exhausted T cell signature gene, TNFRSF4. Additionally, we identified a prognostic gene set (RPS10, MIF, MT-ATP6, CSTB, IFI30, NPC2, BTG1, CTSD, FCGR2A, SEC61G, IER3, HSPB1, HMOX1, and ZFP36L1) and differentiated high-risk from low-risk PDAC patients based on median risk score threshold. …”
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A hybrid CNN-Bi-LSTM model with feature fusion for accurate epilepsy seizure detection by Xiaoshuai Cao, Shaojie Zheng, Jincan Zhang, Wenna Chen, Ganqin Du

“…In the three-class classification task A-D-E on the Bonn dataset, the model performed excellently, achieving 96.19% accuracy, 95.08% sensitivity, 97.34% specificity, 97.49% precision, and 96.18% F1-score. In addition, the proposed method was further validated on the larger and more clinically relevant CHB-MIT dataset, achieving average metrics of 98.43% accuracy, 97.84% sensitivity, 99.21% specificity, 99.14% precision, and an F1 score of 98.39%. …”
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An analysis of cohesive Devices in Sa'di's Būstān and its aesthetic impact within the framework of Halliday's systemic functional theory by Omid Azad

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Global cervical cancer elimination: quantifying the status, progress, and gaps by Liangru Zhou, Yi Li, Hongyun Wang, Ruixi Qin, Zhen Han, Ruifeng Li

“…Most of these were in Europe (41, 30.83%), Asia (32, 24.06%), and North America (20, 15.04%). Additionally, 126 countries (44 (34.92%) HICs and 82 (65.08%) LMICs)) had published national guidelines on CC management. …”
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Evaluation of Knowledge and Practice of Pharmacy Professionals regarding the Risk of Medication Use during Pregnancy in Dessie Town, Northeast Ethiopia: A Cross-Sectional Study by Abdu Tuha, Yilak Gurbie, Haftom Gebregergs Hailu

“…There was a significant difference observed for study college and years of experience of the PPs in their score of knowledge test (p=0.020 and p=0.024, respectively). Additionally, there was a difference seen for gender (p=0.030), study college (p=0.036), and working institution (p=0.013) in their advice to pregnant women. …”
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The fastest nonprofessional age group IRONMAN triathletes in the world originate from Europe by Beat Knechtle, Elias Villiger, Katja Weiss, David Valero, Thomas Rosemann, Pantelis T. Nikolaidis, Rodrigo Luiz Vancini, Marilia Santos Andrade, Mabliny Thuany

“…Sex, age group, country of origin of the athletes, location and year of the event, split times, overall race times, and transition times were obtained. Additionally, the dataset was augmented with specific data (i.e. event characteristics such as temperatures for water and air and course characteristics for all three split disciplines) related to the different race locations. …”
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Deep Learning for Discrimination of Early Spinal Tuberculosis from Acute Osteoporotic Vertebral Fracture on CT by Liu W, Wang J, Lei Y, Liu P, Han Z, Wang S, Liu B

“…Wenjun Liu,1 Jin Wang,2 Yiting Lei,1 Peng Liu,3 Zhenghan Han,1 Shichu Wang,1 Bo Liu1 1Department of Orthopedics, First Affiliated Hospital, Chongqing Medical University, Chongqing, People’s Republic of China; 2College of Medical Informatics, Chongqing Medical University, Chongqing, People’s Republic of China; 3Department of Orthopedics, Daping Hospital, Army Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Bo Liu, Department of Orthopedics, First Affiliated Hospital, Chongqing Medical University, Chongqing, People’s Republic of China, Tel +8613996065698, Email boliu@hospital.cqmu.edu.cnBackground: Early differentiation between spinal tuberculosis (STB) and acute osteoporotic vertebral compression fracture (OVCF) is crucial for determining the appropriate clinical management and treatment pathway, thereby significantly impacting patient outcomes.Objective: To evaluate the efficacy of deep learning (DL) models using reconstructed sagittal CT images in the differentiation of early STB from acute OVCF, with the aim of enhancing diagnostic precision, reducing reliance on MRI and biopsies, and minimizing the risks of misdiagnosis.Methods: Data were collected from 373 patients, with 302 patients recruited from a university-affiliated hospital serving as the training and internal validation sets, and an additional 71 patients from another university-affiliated hospital serving as the external validation set. …”
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Red blood cell parameters as biomarkers of retinopathy of prematurity in preterm infants born before 30 weeks of gestation by Hajime Maeda, Hayato Go, Hajime Iwasa, Shun Hiruta, Hirotaka Ichikawa, Yukinori Sugano, Kei Ogasawara, Nobuo Momoi, Tetsuju Sekiryu, Mitsuaki Hosoya

“…After adjusting for confounders, we observed associations between ROP treatment and mean corpuscular volume (MCV) values > 117.3 fL at birth (adjusted odds ratio [aOR]:2.3; 95% confidence intervals CI 1.0–5.3). …”
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Effect of ultrasonically-activated irrigation protocols used for regenerative endodontics on removal of dual species biofilm in a three-dimensionally printed tooth model: in vitro... by Saeed Mustafa, Marwa A. Meheissen, Sybel Moussa, Rania ElBackly

“…Furthermore, the use of PUI did not significantly enhance antibacterial effects of NaOCl.…”
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Integrated analysis of the transcriptome and hormone metabolome elucidates the regulatory mechanisms governing walnut bud germination by Kai Zhao, Xiaofan Wu, Bo Liang, Shuang Gao, Jieyan Yang, Yan Bai, Yaru Wang, Xin Tian, Fang Wang, Xiuqing Yang

“…Our results emphasized four key biological processes—cellular response to ethylene stimulus, phenylpropanoid metabolic process, ethylene-activated signaling pathway, and monooxygenase activity—along with several relevant pathways, including plant hormone signal transduction, flavone and flavonol biosynthesis, biosynthesis of secondary metabolites, and MAPK signaling pathway, all crucial for walnut bud germination. Additionally, bud germination is closely associated with alterations in various hormone signaling pathways, including abscisic acid, auxin, cytokinin, ethylene, gibberellins, jasmonic acid, and salicylic acid. …”
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Prophylactic ECMO Support during Elective Coronary Percutaneous Interventions in High-Risk Patients: A Single-Center Experience by Claudiu Ungureanu, Marc Blaimont, Hugues Trine, Pierre Henin, Romain Courcelle, Yves Laurent, Patrick Van Ruyssevelt, Caroline Lepièce, Vincent Huberlant

“…PCI was successful in all of the patients with revascularization of all target and additional lesions. Eight of the 9 patients survived for at least 30 days after the procedure, and 7 patients survived for 3 years after the procedure. …”
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Variations in rumen microbiota and host genome impacted feed efficiency in goat breeds by Alaa Emara Rabee, Ibrahim Abou-souliman, Ahmed I. Yousif, Mebarek Lamara, Mohamed A. El-Sherbieny, Eman Ali Elwakeel, Ahmed M. Sallam

“…The animals were genotyped using the Illumina 65KSNP chip arrays v2, and their rumen bacteria and archaea were investigated using PCR-amplicon sequencing of the 16S rRNA gene.ResultsThe results showed that the ZA goats exhibited higher FE than the SH goats (p &lt; 0.05) and a greater relative abundance (p &lt; 0.05) of rumen bacterial groups that are involved in the degradation of cellulose and hemicelluloses, such as Bacteroidota and Fibrobacterota, along with genera such as Prevotella, Lachnospiraceae AC2044 group, Lachnospiraceae NK3A20 group, and Succiniclasticum, which are linked to carbohydrate and nitrogen metabolism pathways. In addition, breed differences were found to affect the proportions of milk fatty acids. …”
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Effects of Adipose-tissue Derived Mesenchymal Stem Cells on PBMCs in Co-culture with HeLa Cell Line by Maryam Dorfaki, mahdi ghatrehsamani, fahimeh Lavi Arab, Mona Roozbehani, Majid Khoshmirsafa, Reza Falak, Fatemeh Keshavarz, Fatemeh Faraji

“…Results: Flow cytometry showed that co-culture of PBMCs/MSCs/HeLa significantly increased the proliferation of PBMCs at different time points, with a p-value of 0.0022. In addition, MSCs significantly decreased apoptosis of PBMCs in co-culture with HeLa at 48 h. the p-value was 0.0022. …”
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Surgical resection versus thermal ablation after intra-arterial conversion therapy for unresectable hepatocellular carcinoma: a multicenter retrospective one as per the STROBE guid... by Yusen Du, Chao An, Wendao Liu

“…However, the cumulative OS and PFS rates in the downstaged cohort were significantly higher than those in the nondownstaged cohort (both ps < 0.001). Additionally, there was no difference in major complications between the two groups (SR: 6.3% vs. …”
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Effect of cytotoxic CD8+ T-cells secretory proteins on hypoxic pancreatic cancer cells. by Eiman Abdo, Mohammad A Ismail, Sabal Al Hadidi, Mairvat Al-Mrahleh, Tareq Saleh, Malik Zihlif, Nidaa A Ababneh

“…A significant decrease in TNF-α and IFN-γ levels was also detected. Additionally, a significant increase in IL-6, p53 and TNF-α gene expression levels was observed in PANC-1 cells treated with CD8+ T-cells CM. …”
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Permanent aquifer storage loss from long-term groundwater withdrawal: A case study of subsidence in Bandung (Indonesia) by Michelle Rygus, Marco Bianchi, Alessandro Novellino, Ekbal Hussain, Ahmad Taufiq, Steven Reinaldo Rusli, Dwi Sarah, Claudia Meisina

“…Our model projections indicate that subsidence will persist, with continued industrial extraction potentially leading to up to 5.6 m of additional subsidence and 11.1 km3 of aquifer storage loss by 2050. …”
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Experiences and Perspectives of Medication Information and Use Among Arabic-Speaking Migrant Women in Sweden: A Multistage Focus Group Study by Al Musawi A, Axelsson M, Eriksson T, Rämgård M

“…Although the adherence patterns of the study subjects resembled those of the general population, unique barriers require additional healthcare support. This study can inform healthcare practices and establish a foundation for further research on medication information and use in this group, including comparisons with native-born individuals.Keywords: medication adherence, migrant health, health equity, vulnerable population, health perception…”
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Vegetation Change and Its Response to Climate Change in Yunnan Province, China by Huaizhang Sun, Jiyan Wang, Junnan Xiong, Jinhu Bian, Huaan Jin, Weiming Cheng, Ainong Li

“…The results indicate that (1) the temporal variation of the NDVI showed that the NDVI values of different vegetation types increased at different rates, especially in growing season, spring, and autumn; (2) for spatial patterns, the NDVI, CV, and NDVI trends had strong spatial heterogeneity owning to the influence of altitudes, slopes, and aspects; and (3) the concurrent effect of vegetation on climate change indicates that the positive effect of temperature on NDVI was mainly in growing season and autumn, whereas spring NDVI was mainly influenced by precipitation. …”
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Ultra-fast biparametric MRI in prostate cancer assessment: Diagnostic performance and image quality compared to conventional multiparametric MRI by Antonia M. Pausch, Vivien Filleböck, Clara Elsner, Niels J. Rupp, Daniel Eberli, Andreas M. Hötker

“…Methods: This prospective single-center study enrolled 123 biopsy-naïve patients undergoing conventional mpMRI and additionally ultra-fast bpMRI at 3 T between 06/2023–02/2024. …”
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