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63401
Examining the impact of probiotic Lactiplantibacillus pentosus 6MMI on inhibiting biofilm formation, adhesion, and virulence gene expression in Listeria monocytogenes ATCC 19115
Published 2025-06-01“…Treatment with cell-free supernatant (CFS) from Lpb. pentosus significantly reduced biofilm formation by 91.25 % and 24.50 % and diminished mature biofilm formation by 83.82 % and 21.80 % on L. monocytogenes. Additionally, the CFS inhibited the transcription of the plcB, hly, and prfA genes in L. monocytogenes, suggesting a potential reduction in bacterial virulence through decreased hemolysin release and modulation of phospholipase activity. …”
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63402
Possibilities of Using Regional Index-Flood Method with Annual Maximum and Partial Duration Series: A Case Study of Susurluk River Basin, Turkey
Published 2025-01-01“…Since partial duration flood estimations are lower than annual maximum flood ones, they can provide advantages to engineering projects with lower costs. In addition, PDS can be useful in regionalizing floods, which are very common due to the data extraction process.…”
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63403
Herpes zoster vaccine and the risk of stroke: a population-based cohort study using linked data from the Clinical Practice Research Datalink
Published 2024-04-01“…The SCCS found no association between herpes zoster vaccination and stroke 30–119 days later.Conclusions Despite our cohort study, with extensive confounder adjustment and an influenza vaccination active comparator, finding herpes zoster vaccination associated with 12%–16% reduced stroke rates, additional analyses suggested this was largely explained by healthy vaccinee bias. …”
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63404
Neighbourhood socioeconomic conditions and emergency admissions for ambulatory care sensitive conditions in children: a longitudinal ecological analysis in England, 2012–2017
Published 2025-01-01“…This was not explained by available measures of differential access to care, suggesting policy interventions should address the causes of unemployment and poverty in addition to health system factors to reduce emergency admissions for ACSCs.…”
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63405
Circadian Rhythms Fluctuate the Treatment Effects of Intravesical Treatments on Rat Urinary Frequency Models
Published 2024-01-01“…Rats were then euthanized, and histopathologic examinations using a damage score validated the severity of bladder inflammation. We used nine additional rats to determine the treatment effect of various drugs against the urinary frequency. …”
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63406
Metagenomics: a new frontier for routine pathology testing of gastrointestinal pathogens
Published 2025-01-01“…Further, the mNGS assay detected 14 additional enteropathogens, that were either not detected or not tested, by initial PCR/MCS testing. …”
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63407
Effects of Lemon Beverage Containing Citric Acid with Calcium Supplementation on Bone Metabolism and Mineral Density in Postmenopausal Women: Double-Blind 11-Month Intervention Stu...
Published 2021-01-01“…Based on our findings, we speculated that bone resorption and bone formation in postmenopausal women might be suppressed along with an increase in Ca resorption caused by chelation of citric acid in association with continuous ingestion of a Ca-supplemented lemon beverage containing citric acid, resulting in suppression of high bone metabolic turnover. In addition, the results provide information regarding BMD maintenance in the bones of the trunk, including the lumbar spine and proximal femur.…”
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63408
Risk factors for lymphatic leakage following radical cystectomy and pelvic lymph node dissection in patients with muscle-invasive bladder cancer
Published 2025-01-01“…On multivariate analysis, higher number of dissected lymph nodes (OR 3.278, 95% CI 1.135–9.471, p = 0.028) was found to be a independent risk factor for lymphatic leakage. Additionally, a positive correlation was observed between the numbers of dissected lymph nodes and lymphatic leakage rate (R = 0.456, p = 0.013). …”
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63409
Prediction of fish (Coilia nasus) catch using spatiotemporal environmental variables and random forest model in a highly turbid macrotidal estuary
Published 2025-05-01“…Further, the results agree with previous research, as spatial distribution plots showed a preference for mature C. nasus habitats 15–16 km upstream from the river mouth. Additionally, the study found that temperature had a negligible effect on short-term CPUE predictions, likely due to its pronounced seasonal variability, suggesting that temperature may not be a critical factor for short-term CPUE predictions. …”
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63410
Proteome‐Wide Mendelian Randomization Identifies Therapeutic Targets for Abdominal Aortic Aneurysm
Published 2025-02-01“…Sequential analyses of colocalization and summary‐data‐based Mendelian randomization were performed to verify the causal roles of candidate proteins. Additionally, single‐cell expression analysis, protein–protein interaction network analysis, pathway enrichment analysis, and druggability assessments were conducted to identify cell types with enriched expression and prioritize potential therapeutic targets. …”
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63411
Occurrence of Enteric Viruses in Surface Water and the Relationship with Changes in Season and Physical Water Quality Dynamics
Published 2020-01-01“…Neither wet season nor dry season was significantly associated with the prevalence of the viruses. …”
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63412
Factor V H1299r (Hr2) Heterozygosity: A Risk Factor For Recurrent Implantation Failure Particularly In Non-Carriers For Factor V Leiden Mutation-A Case-Control Study
Published 2022-12-01“…Results: Recurrent implantation failure group displayed a significantly higher prevalence of FV HR2 heterozygosity than fertile controls while the frequency of FV Leiden mutation was comparable between groups (p=0.011; p=0.619). Additionally, the difference in the prevalence of other specific or total gene mutations among women with recurrent implantation failure was also insignificant. …”
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63413
Global, regional, and national burden of early-onset colorectal cancer from 1990 to 2021: a systematic analysis based on the global burden of disease study 2021
Published 2025-01-01“…The concentration index revealed that high-SDI countries had a greater burden of EOCRC than low-SDI countries. …”
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63414
Delivery, maternal and neonatal outcomes in nulliparous women with gestational diabetes undergoing epidural labour analgesia: a propensity score-matched analysis
Published 2022-07-01“…The duration of the first and total stages of labour was prolonged, the occurrence of postpartum fever increased, and the duration of hospital stay was shortened in those receiving ELA (all p<0.05). Additionally, neonatal birth weight, plasma glucose levels and neonatal macrosomia occurrence increased, while neonatal intensive care unit admissions and neonatal hypoglycaemia decreased in the ELA versus the NELA group (all p<0.05). …”
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63415
Intramuscular Injection of Adenoassociated Virus Encoding Human Neurotrophic Factor 3 and Exercise Intervention Contribute to Reduce Spasms after Spinal Cord Injury
Published 2019-01-01“…However, combination therapy did not show a significant additive effect, which needs to be improved by adjusting the combined strategy.…”
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63416
Rational design of novel phenol ether derivatives as non-covalent proteasome inhibitors through 3D-QSAR, molecular docking and ADMET prediction
Published 2023-12-01“…The results suggested that hydrogen bond and hydrophobic interaction played a key role in binding interaction between the receptor and ligand. In addition, the results of ADMET prediction indicated that the new designed compounds had reasonable PK parameters and drug-like properties. …”
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63417
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63418
Association of Albumin‐To‐Creatinine Ratio With Diabetic Retinopathy Among US Adults (NHANES 2009–2016)
Published 2025-01-01“…This study assesses the predictive efficacy of the urinary serum albumin‐to‐creatinine ratio (UACR/SACR Ratio) against traditional biomarkers such as the serum albumin‐to‐creatinine ratio (SACR) and urinary albumin‐to‐creatinine ratio (UACR) for evaluating DR risk. Additionally, the study explores the potential of these biomarkers, both individually and in combination with HbA1c, for early detection and risk stratification of DR. …”
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63419
Advancing soil-structure interaction (SSI): a comprehensive review of current practices, challenges, and future directions
Published 2025-01-01“…Historical seismic events, such as the Kobe and Loma Prieta earthquakes, are analysed to underscore the detrimental consequences of neglecting SSI considerations. Additionally, the review discusses recent innovations, including the application of machine learning and advanced computational tools, and their potential to enhance the accuracy and efficiency of SSI analysis. …”
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63420
Trace metals potential human health risks assessment through consuming common food spices in Ado Ekiti, Southwest, Nigeria
Published 2025-03-01“…EDI follows the order: Fe > Cr > Pb > Cd > As. EDI for Cr (0.133 mg/kg) exceeded the reference dose (RfD). …”
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