Ritonavir loaded solid lipid nanoparticles for oral drug delivery and bioavailability enhancement by Ananda Kumar Chettupalli, Sarad Pawar Naik Bukke, Shaik Abdul Rahaman, Aziz Unnisa, Madhumitha Adepu, Marati Kavitha, Molakpogu Ravindra Babu, Bayapa Reddy Narapureddy, Hope Onohuean

“…The optimized RN-SLN formulation showed a particle size of 265.06 ± 5.12 nm, % EE of 86.2 ± 3.16 and cumulative drug release of 94.8 ± 0.16%. In addition, in-vitro drug release studies confirmed a biphasic release pattern, and followed Higuchi’s model. …”
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Comparison of oxidative stress status in the kidney tissue of male rats treated with paraquat and nanoparaquat by Fatemeh Bahramibanan, Mohammad Vahabi Rad, Akram Ranjbar, Ashkan Karbasi, Anahita Abbasifard

“…However, treatment with nanoparaquat α and β resulted in a decrease in LPO levels compared to the paraquat-treated group. Additionally, when nanoparaquat α and β were administered in combination with NAC, a further reduction in LPO levels was observed compared to the PQ treated group. …”
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Effectiveness of mental health interventions for older adults in South Asia: A scoping review. by Hoimonty Mazumder, Farah Faizah, Easter Protiva Gain, Irfath Sharmin Eva, Kaniz Ferdouse Mou, Nobonita Saha, Farzana Rahman, Jyoti Das, A M Khairul Islam, Fazilatun Nesa, M Mahbub Hossain

“…<h4>Methods</h4>We searched six electronic databases and additional sources for experimental/non-experimental studies evaluating the effectiveness of geriatric mental health interventions in eight countries in the South Asia region from the date of inception of each database up to August 5, 2022. …”
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Optimization of the Solid-state Fermentation Process for Morchella esculenta Fermented Wheat and Analysis of Its Nutritional Components, Physicochemical Properties and Antioxidant... by Dandan GU, Xue DONG, Jinxiu ZHANG, Xiaoru WANG, Zongshuo ZHAO, Li'an WANG

“…The soluble dietary fiber (SDF) increased by 43.70%, whereas the insoluble dietary fiber (IDF) decreased by 19.24%, with no significant change in the total dietary fiber (TDF). Additionally, the water-holding capacity, unsaturated fatty acid adsorption capacity, saturated fatty acid adsorption capacity, and swelling capacity of FFW increased by 77.84%, 11.49%, 25.00%, and 26.00%, respectively. …”
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An engineering model for creeping flame spread over idealized electrical wires in microgravity by Coimbra, Alain, Li, Yutao, Guibaud, Augustin, Citerne, Jean-Marie, Legros, Guillaume, Consalvi, Jean-Louis

“…The heat transfer mechanisms ahead of the pyrolysis front are investigated with a special emphasis on the LDPE thickness and the conductivity of the metallic core. In addition to NiCr, metallic cores of lower and higher conductivities are considered. …”
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Effect of taking a dietary supplement containing Lactobacillus delbrueckii subsp. bulgaricus on clinical manifestations of functional dyspepsia and patients’ quality of life by I.G. Paliy, S.V. Zaika, O.O. Ksenchyn, I.V. Chernova

“…The score on the Gastrointestinal Symptom Rating Scale was analyzed before treatment, after completing a 15-day course of taking the probiotic additive, which contained Lactobacillus delbrueckii subsp. bulgaricus, and 15 days after the end of the course. …”
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Subglacial discharge effects on basal melting of a rotating, idealized ice shelf by I. Vaňková, X. Asay-Davis, C. Branecky Begeman, D. Comeau, A. Hager, M. Hoffman, S. F. Price, J. Wolfe

“…Furthermore, in the rotating case, the addition of channelized, subglacial discharge can produce either a higher or a lower ice-shelf basal melt-flux anomaly than the equivalent amount of distributed discharge, depending on its location along the grounding line relative to the directionality of the Coriolis force. …”
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Development of a Sustainable Flexible Humidity Sensor Based on <i>Tenebrio molitor</i> Larvae Biomass-Derived Chitosan by Ezekiel Edward Nettey-Oppong, Riaz Muhammad, Emmanuel Ackah, Hojun Yang, Ahmed Ali, Hyun-Woo Jeong, Seong-Wan Kim, Young-Seek Seok, Seung Ho Choi

“…This mechanism was further elucidated through molecular dynamics simulations, revealing that the conductivity in the sensor is modulated by proton mobility, which operates via the Grotthuss mechanism under high-humidity and the packed-acid mechanism under low-humidity conditions. Additionally, the chitosan-based humidity sensor was further seamlessly integrated into an Internet of Things (IoT) framework, enabling wireless humidity monitoring and real-time data visualization on a mobile device. …”
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Treating shock with norepinephrine administered in midline catheters in an intermediary care unit: a retrospective cohort study by Gustav Torisson, Marcus Ohlsson, Hanna Karlsson, Ajnaz Afrasiabi, Viktor Månsson, Hannes Hartman

“…Secondary outcomes included patient outcomes after intermediary care (either deceased, discharged to regular ward care or intensive care) and the need for additional central lines.Results Of 474 eligible patients, 472 were included, with a median (IQR) age of 73.5 (65–80) years, with 281 (60%) men. …”
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Association between fasting blood glucose and psychotic symptoms in Chinese patients with first-episode drug-naïve major depressive disorder by Xingzhi Xia, Hanxu Deng, Wei Ren, Lin Yang, Yingzhao Zhu, Yaozhi Liu, Junjun Liu, Xueli Zhao, Fengnan Jia, Xiangdong Du, Xiangyang Zhang

“…The aim of this study was to investigate the relationship between FBG and PD in a Chinese population with first-episode drug-naïve (FEDN) major depressive disorder (MDD). Methods In this study, 1718 outpatient individuals diagnosed with first-episode drug-naïve major depressive disorder (FEDN MDD) were included. …”
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Plant Detection in RGB Images from Unmanned Aerial Vehicles Using Segmentation by Deep Learning and an Impact of Model Accuracy on Downstream Analysis by Mikhail V. Kozhekin, Mikhail A. Genaev, Evgenii G. Komyshev, Zakhar A. Zavyalov, Dmitry A. Afonnikov

“…Twelve orthomosaics were collected and marked at several sites in Russia to train and test the neural network algorithms. Additionally, 17 existing datasets of various spatial resolutions and markup quality levels from the Roboflow service were used to extend training image sets. …”
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Related studies on measuring the normal values of optic nerve sheath diameter in healthy Chinese adults based on CT scans by Lei Han, Ning Su, Chao Wu, Jiamin Yang, Xiaolin Liu

“…The comparison of parameters between different genders showed that the values of all parameters in males were greater than those in females, and the difference between the two groups was statistically significant (P < 0.001). In addition, we further measured the ONSD/ETD values, which averaged 0.24 (0.23–0.24) at 3 mm and 0.19 (0.19–0.20) at 10 mm. …”
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Eco-reliable operation based on clean environmental condition for the grid-connected renewable energy hubs with heat pump and hydrogen, thermal and compressed air storage systems by Aboulbaba Eladeb, Ali Basem, Aman Sharma, Aashim Dhawan, Prabhat Sharma, Mohamed Bouzidi, Lioua Kolsi, Elnaz Naderi Drehshori

“…Subject to the operating model and reliability restrictions of these networks, the suggested strategy seeks to reduce the overall estimated costs of energy procurement, dependability, and emissions within the designated networks. Additional constraints of the problem encompass the operational model of sources and storages, conceptualized as an energy hub. …”
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Light exposure profiles differ between myopes and non-myopes outside school hours by John G Lawrenson, Rakhee Shah, Rohit Dhakal, Byki Huntjens, Pavan Kumar Verkicharla

“…Purpose Considering the putative role of light in myopia, and variations in socioeconomic, lifestyle, educational and environmental factors across ethnicities, we objectively investigated light exposure patterns in Indian school children.Methods The light exposure profile of 143 school children (9–15 years, 50 myopes) recorded using a validated wearable light tracker for six continuous days was analysed. Additional data for non-school days were available for 87 children (26 myopes). …”
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Exercise-induced methylation of the Serhl2 promoter and implication for lipid metabolism in rat skeletal muscle by Mutsumi Katayama, Kazuhiro Nomura, Jonathan M. Mudry, Alexander V. Chibalin, Anna Krook, Juleen R. Zierath

“…Methods: We utilized endurance-trained rats, cultured L6 myotubes, and human skeletal muscle cells, employing MeDIP sequencing, gene silencing, and palmitate oxidation assays. Additional methods included promoter luciferase assays, fluorescence microscopy, and RNA/DNA analysis to investigate exercise-induced molecular changes. …”
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Genotypic and phenotypic characterization of antimicrobial resistance in Salmonella strains isolated from both No-Antibiotics-Ever (NAE) and conventional broiler complexes by Yagya Adhikari, Dianna V. Bourassa, Sabin Poudel, Matthew A. Bailey, Richard J. Buhr, Kenneth S. Macklin

“…Interestingly, 80 % (32/40) of Kentucky isolates showed phenotypic resistance to either tetracycline or sulfisoxazole or both. In addition, the odds of ATR Salmonella detection were 7 times (1.37 – 43.45; 95 % CL) more likely in the isolates from NAE complex as compared to conventional broiler complex (p = 0.0233). …”
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The Frequency Dependence of Poisson’s Ratio in Fluid-Saturated Rocks by Liming Zhao, Tongjun Chen, Xin Zhang, Tao Xing

“…Then, we conducted a numerical example to indicate the effect of influence factors (the concentrations of stiff and soft pores, the aspect ratio of soft pores, and the pore fluid bulk modulus) on Poisson’s ratio from undrained state to unrelaxed state, and validated the theoretical analysis by the published experimental data. In addition, based on 1/Qν, we reanalyzed and validated the relationship between different attenuation modes (i.e., bulk attenuation 1/QK, P-wave attenuation 1/QP, extensional attenuation 1/QE, and S-wave attenuation 1/QS): (1) when 1/Qν is positive, the relationship between them is 1/QK>1/QP>1/QE>1/QS; when 1/Qν is 0, the relationship between them is 1/QK=1/QP=1/QE=1/QS; and when 1/Qν is negative, the relationship between them is 1/QK<1/QP<1/QE<1/QS. …”
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Novel machine learning-driven comparative analysis of CSP, STFT, and CSP-STFT fusion for EEG data classification across multiple meditation and non-meditation sessions in BCI pipel... by Nalinda D. Liyanagedera, Corinne A. Bareham, Heather Kempton, Hans W. Guesgen

“…At the same time, the highest mean classification accuracy for the 12 participants was achieved using the pipeline with the combination of CSP STFT algorithm, reaching 75.5% for LKM-Self/ non-meditation for the case of 5 sessions of data. Additionally, the highest individual classification accuracy of 88.9% was obtained by the participant no. 14. …”
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National Patient Satisfaction Survey as a Predictor for Quality of Care and Quality Improvement &ndash; Experience and Practice by Cui J, Du J, Zhang N, Liang Z

“…Patient care experiences also varied across different hospital categories. In addition, the maturity of the Health Information Management System (HIMS) positively influenced inpatient satisfaction (p < 0.05).Conclusion: A nationwide patient satisfaction survey can predict benefits of quality improvement initiatives and identify changing trends in the quality of hospital care. …”
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Genetic association analysis of lipid-lowering drug target genes in chronic kidney disease by Yi Zhang, Yi Zhang, Guangyang Ou, Lei Peng, Jian Pan, Shaohua Zhang, Jianguo Shi

“…Regarding secondary outcomes, lipid-lowering drugs did not significantly affect eGFR and BUN levels. …”
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