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62661
Safety of health workers during the COVID-19 pandemic and beyond: piloting WHO framework in Iran
Published 2025-02-01“…Data collected (qualitative and quantitative) using national digital health records, staff records, and indicator-specific tools. In addition to measuring the indicator’s value, the indicators’ feasibility was also assessed. …”
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62662
Development and evaluation of multiplex real-time PCR for rapid identifying major pathogenic mycobacteria from pulmonary and extrapulmonary clinical samples in eastern China
Published 2025-01-01“…The accuracy of the Multiplex PCR was validated with DNA from 228 known clinical samples confirmed by Targeted next-generation sequencing (tNGS). Additionally, 901 consecutive clinical samples were assessed to evaluate the Multiplex PCR's diagnostic performance in detecting mycobacteria in pulmonary and extrapulmonary samples. …”
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62663
Hippocampal dendritic spines store-operated calcium entry and endoplasmic reticulum content is dynamic microtubule dependent
Published 2025-01-01“…After store depletion in primary hippocampal neurons, the wild type STIM2 is redistributed from the necks to the heads of dendritic spines, while the STIM2 variant with a mutation that disrupts the interaction with EB proteins is excluded from dendritic spines. In addition, overexpression of the mutant variant leads to ER reorganization in neuronal soma and reduction of ER presence in spines. …”
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62664
Prediction of time-dependent bearing capacity of concrete pile in cohesive soil using optimized relevance vector machine and long short-term memory models
Published 2024-12-01“…Each optimized RVM and LSTM model has been trained and tested by 100 and 26 datasets. In addition, the effect of structural and database multicollinearities has been analyzed on models’ prediction capabilities. …”
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62665
Preliminary Clinical Study on Therapy of Lidocaine Local Block Combined with Acupuncture-rehabilitation in Treatment of Post-stroke Upper Limb Spasticity
Published 2021-06-01“…The MAS grade, FMA-UE, MBI, and AROM scores of the two groups improved significantly after treatment compared with those before treatment, as the differences were statistically significant(<italic>P</italic><0.01).In addition, MAS grade in the observation group exhibited a substantial improvement compared with the control group after treatment(<italic>P</italic><0.01). …”
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62666
Medical honey for canine nasal intertrigo: A randomized, blinded, placebo-controlled, adaptive clinical trial to support antimicrobial stewardship in veterinary dermatology.
Published 2020-01-01“…To minimize this risk, we tested the effectiveness of medical-grade Manuka honey at treating intertrigo as compared to a placebo hydrogel. We additionally characterized the culturable microbial flora of intertrigo and recorded any adverse effect with either treatment. …”
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62667
Effect of High-Frequency Repetitive Transcranial Magnetic Stimulation on Patients with Post-Stroke Comorbid Cognitive Impairment and Depression
Published 2024-04-01“…The observation group received high-frequency rTMS treatment (stimulation of the left dorsolateral prefrontal cortex, 10 Hz, 100% resting motion threshold, 20 minutes a time, once a day, five days a week) for four weeks, in addition to the treatment received by the control group. …”
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62668
Longitudinal association between hemoglobin and lung function with insights into the incidence of airflow obstruction: an observational study
Published 2025-01-01“…Methods We used linear mixed regression analysis to evaluate the longitudinal associations between Hb levels and lung function parameters, including forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), and FEV1/FVC. Additionally, we used a generalized estimating equation to calculate the odds ratio (OR) of airflow obstruction (AO) according to the Hb level. …”
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62669
Evaluating the impact of ESICM 2023 guidelines and the new global definition of ARDS on clinical outcomes: insights from MIMIC-IV cohort data
Published 2025-01-01“…The XGBoost classifier, trained to predict subphenotypes, achieved an AUC of 0.88 ± 0.02 on the training set. Additionally, mortality was significantly associated with patients with hypoxemia compared with survivors, particularly regarding respiratory parameters. …”
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62670
Perceptions and Motivations of Japanese Medical Students Regarding Course Evaluations: A Cultural Perspective
Published 2025-02-01“…Gratitude positively influenced their decision to participate in course evaluations, whereas anger, anxiety about presumptuousness, fear and indifference had a negative impact. Additionally, their willingness to participate was positively influenced by the perceived benefits for future students. …”
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62671
Using XBGoost, an interpretable machine learning model, for diagnosing prostate cancer in patients with PSA < 20 ng/ml based on the PSAMR indicator
Published 2025-01-01“…We developed an XGBoost machine learning model based on the PSAMR indicator and interpreted it using the SHapley Additive exPlanations method. The model offered a high-performance non-invasive technique to diagnose prostate cancer in patients with PSA levels < 20 ng/ml.…”
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62672
Multicomponent Dietary Supplementation: Impact on Tear Secretion and Ocular Surface Inflammation in Dry Eye Syndrome Patients
Published 2025-01-01Subjects: “…dry eye syndrome…”
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62673
Dual Functions of Androgen Receptor Overexpression in Triple-Negative Breast Cancer: A Complex Prognostic Marker
Published 2025-01-01“…In high AR-DIA patients with unfavorable characteristics, ACT did not improve survival, and patients may benefit from AR-targeted therapy. …”
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62674
lncRNA-KCNQ1OT1: A Potential Target in Exosomes Derived from Adipose-Derived Stem Cells for the Treatment of Osteoporosis
Published 2021-01-01“…However, miR-141-5p silencing or cocultured with ADSCs-Exos attenuated these effects. In addition, KCNQ1OT1-Exos could more significantly attenuate the induced cytotoxicity and apoptosis compared to ADSCs-Exos. …”
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62675
Zinc Supplementation Prevented Type 2 Diabetes-Induced Liver Injury Mediated by the Nrf2-MT Antioxidative Pathway
Published 2021-01-01“…This was followed by zinc treatment at 5 mg/kg body weight given every other day for 3 months. Global metabolic disorders of both glucose and lipids were unaffected by zinc supplementation. …”
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62676
Predicting largest expected aftershock ground motions using automated machine learning (AutoML)-based scheme
Published 2025-01-01“…Abstract Aftershocks can cause additional damage or even lead to the collapse of structures already weakened by a mainshock. …”
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62677
A cross-sectional study on posttraumatic growth and influencing factors among parents of premature infants
Published 2025-01-01“…The total score of coping style of parents of premature infants was (34.28 ± 4.97) points, which was in the middle and upper level; the total score of social support of parents of premature infants was (14.28 ± 4.97) points, which was in the middle level. In addition, older gestational age at birth (B = 2.396, P < 0.001) ,higher Apgar score at 5 min at birth (B = 2.117, P = 0.023), positive coping style (B = 0.850, P < 0.001), and higher social support score (B = 1.978, P < 0.001) were associated with higher PTG scores. …”
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62678
Electrocatalytic detection of Acetaminophen by sodium ferrite
Published 2025-01-01“…Hence, its monitoring in the human body, pharmaceutical preparations and consumption sources is important. …”
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62679
Impact of Exercise on Tramadol-Conditioned Place Preference
Published 2025-01-01“…This attenuation was associated with a significant increase in <i>Bdnf</i> mRNA expression in the Hipp and NAc, but not the PFC. Additionally, the TRA-induced elevations in <i>Il-1β</i> mRNA expression were reversed by all durations of exercise in Hipp. …”
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62680
Continuous Glucose Monitoring Among Patients With Type 1 Diabetes in Rwanda (CAPT1D) Phase I: Prospective Observational Feasibility Study
Published 2025-01-01“…Phase II and Phase III extended CGM use for an additional 6 months respectively, using the next-generation Dexcom G7 CGM. …”
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