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62521
Relationship between multiple morbidities and performance on the Timed Up and Go test in elderly patients: a cross-sectional study
Published 2025-01-01“…All analyses were performed using SPSS software.Results A total of 160 participants (mean age: 67.2±6.9 years and body mass index (BMI): 28.7±4.9 kg/m²) were included. …”
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62522
Association between early‐stage diabetic nephropathy and the delayed monophasic glucose peak during oral glucose tolerance test in type 2 diabetes mellitus
Published 2025-02-01“…In logistic regression, ISSI‐2 was independently associated with the delay in glucose peak time in patients with T2DM (OR 0.839; 95% CI 0.776–0.907; P < 0.001). Additionally, 2‐h plasma glucose, OGIS, and AUCC‐peptide0–180 min were independently associated with delayed peak glucose time (all P < 0.001). …”
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62523
Enhancing semantical text understanding with fine-tuned large language models: A case study on Quora Question Pair duplicate identification.
Published 2025-01-01“…To ensure a fair comparison, we followed our previous study's design and dataset by employing a 10-fold cross-validation for supervised model training and evaluation. Additionally, we conducted a secondary study by introducing a recent larger LLM with 70B parameters and comparing it with the 7B model using the GLUE benchmark, and both models were finetuned with the corpus. …”
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62524
Prevalence and immunopathologic characteristics of seropositive and seronegative hepatitis B virus-associated membranous nephropathy: a retrospective study of 420 biopsy-proven cas...
Published 2024-12-01“…The anti-PLA2R antibody-positive group displayed higher levels of urine protein (p < .05), serum cholesterol (p < .01), and IgG4 subtypes (p < .05) compared to the negative group. Additionally, the positive group had significantly lower levels of serum albumin and IgG than the negative group (p < .01).Conclusions This comprehensive study reveals a significantly higher prevalence of seronegative HBV-MN than previously thought. …”
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62525
Effects of Whey Protein Concentrate on the Bioaccessibility and Microstructure of 5-Methyltetrahydrocalcium Folate in Simulated Digestive Environment in Vitro
Published 2025-02-01“…According to the findings, 5-MTHF could be securely wrapped, shielded by WPC throughout the stomach stage of digestion, and then moved to the small intestine for full release. Additionally, during the digestive process, the bioaccessibility of WPC-5-MTHF tended to rise in all groups. …”
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62526
No microorganism was detected in amniotic fluid of healthy pregnancies from the second trimester to the delivery
Published 2025-01-01“…Cohort 2 contained 22 women who experienced infection-related adverse pregnancy outcomes (including preterm birth, histological chorioamnionitis, and stillbirth), with only their second trimester AF samples (n = 24) examined. Additionally, multiple procedural negative controls and technical positive controls were applied to this study to remove potential contamination. …”
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62527
Sign Language Recognition System for Deaf Patients: Protocol for a Systematic Review
Published 2025-01-01“…A PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) flow diagram will be presented to visually summarize the screening process, ensuring clarity and transparency in presenting the results. Additionally, a comprehensive chart table will be constructed to consolidate essential data related to the key variables extracted from the studies. …”
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62528
Retrospective evaluation of multiplex PCR panel results from CSF samples in a university hospital
Published 2025-01-01“…Nine patients were found to have Streptococcus pneumoniae, two had Varicella zoster virus, and two had Enterovirus. Additionally, six patients had separate detections of Haemophilus influenzae, Cytomegalovirus, Herpes simplex virus 1, Human herpesvirus 6, Human herpesvirus 8, and Parechoviruses. …”
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62529
The Application of Incretin-Based Pharmacotherapy in the Contemporary Management of Type 2 Diabetes: A Review of the Literature
Published 2025-01-01“…While metformin remains a cornerstone of treatment, incretin-based therapies like GLP-1 receptor agonists and DPP-4 inhibitors provide additional benefits, including glycemic control, weight management, and organ protection, making them essential in personalized care. …”
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62530
From consumers to pioneers: insights from thermal energy communities in Denmark, Germany and the Netherlands
Published 2025-01-01“…External factors such as high oil prices, seismic events, and recent rising energy prices have also spurred project initiation. TECs also rely on additional factors for success, including organisational and entrepreneurial abilities to engage with stakeholders, gain social acceptance, and secure commitment from community members. …”
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62531
Genetic aspects of potato resistance to phytophthorosis
Published 2021-04-01“…We can also investigate this process by changing the profile of secondary metabolites of the host and the pathogen. In addition to fundamental work in this area, applied work in the form of the development of new preparations for protecting potatoes is of no less importance. …”
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62532
Application of wet compress with self-made moisturizing antipruritic lotion in the treatment of chronic eczema and related nursing management (自拟润肤止痒洗剂湿敷治疗慢性湿疹的护理体会)...
Published 2023-02-01“…The control group was given Chinese herbal medicine external application, and the observation group was additionally treated by wet compress with self-designed moisturizing antipruritic lotion based on the treatment of the control group. …”
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62533
The antibacterial and antifungal potential of marine natural ingredients from the symbiont bacteria of mangrove
Published 2023-10-01“…Therefore, this study aimed to examine symbiont bacteria in the fruit and leaves of Xylocarpus granatum as additional raw materials for anti-acne cosmetic creams and moisturisers.METHODS: Symbiont bacteria were isolated using the pour plate method through Zobell 2216E and incubated for 2 x 24 hours at 27.5 Celcius degree. …”
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62534
Performance Understanding and Learning System (PULSE-KEY): development of a framework for implementation and performance evaluation of healthcare delivery models of care
Published 2024-12-01“…Building on this previous work, the present study advances the framework development through four additional stages: (4) development of a conceptual framework (identifying, categorising, synthesising concepts into outcome domains), (5) expert consultation, (6) validation using a real-world case study and (7) refinement for practical applicability and effectiveness in evaluating alternative healthcare delivery models of care.Results The framework was developed by synthesising insights from phases 1–3 of our previously published work and refined through consultations with 25 experts, confirming its relevance, clarity and suitability for diverse audiences. …”
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62535
Effects of Sex and Age on Quadriceps and Hamstring Strength and Flexibility in High School Basketball Athletes
Published 2021-10-01“…# Background Eccentric hamstring strength and hamstring/quadriceps strength ratios have been identified as modifiable risk factors of hamstring strains. Additionally, those strength and flexibility characteristics are commonly used as clinical tests to monitor progress of athletes with acute or chronic hamstring strains. …”
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62536
Exploiting gasdermin-mediated pyroptosis for enhanced antimicrobial activity of phage endolysin against Pseudomonas aeruginosa
Published 2025-01-01“…ABSTRACT Pyroptosis is an inflammatory immune response of eukaryotic cells to bacterial lipopolysaccharide (LPS) and other pathological stimuli, leading to the activation of the gasdermin D (GSDMD) and secretion of pore-forming domain GSDMDNterm, facilitating the release of cytokines. Additionally, GSDMDNterm exhibits antibacterial properties through interactions with bacterial outer membranes (OM). …”
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62537
Exploring Effects of Mental Stress with Data Augmentation and Classification Using fNIRS
Published 2025-01-01“…The study is carried out at two separate times of day (morning and evening) and involves 21 healthy participants. Additionally, we introduce binaural beats (BBs) stimulation to investigate its potential for stress reduction. …”
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62538
A genome-wide association study identifies five loci influencing facial morphology in Europeans.
Published 2012-09-01“…Our finding at PAX3 influencing the position of the nasion replicates a recent GWAS of facial features. In addition to the reported GWA findings, we established links between common DNA variants previously associated with NSCL/P at 2p21, 8q24, 13q31, and 17q22 and normal facial-shape variations based on a candidate gene approach. …”
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62539
Evaluation of Preptin and other Biomarkers in Coronary Artery Disease Patients with and without Diabetes Mellitus
Published 2024-12-01“…Conjugated with insulin, it is produced by β-cells from the pro-insulin-like growth factor 2 E-peptide. However, in addition to insulin, pancreatic hormone (Preptin) is released in response to elevated blood glucose levels. …”
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62540
Occurrence Mechanism of Roof-Fall Accidents in Large-Section Coal Seam Roadways and Related Support Design for Bayangaole Coal Mine, China
Published 2018-01-01“…Accordingly, the entire stratum was separated into several thin sublayers, significantly reducing the stability of roof. In addition, the roof medium grained sandstone of roadway is water-rich strata, and water aggravates the damage of roof. …”
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