Characterizing PM2.5 Secondary Aerosols via a Fusion Strategy of Two-stage Positive Matrix Factorization and Robust Regression by Chun-Sheng Huang, Ho-Tang Liao, Chia-Yang Chen, Li-Hao Young, Ta-Chih Hsiao, Tsung-I Chou, Jyun-Min Chang, Kuan-Lin Lai, Chang-Fu Wu

“…To overcome this limitation, we employed a two-stage PMF modeling approach with adjustments of the species weighting, which was fused with a robust regression model to better characterize the sources of PM2.5 secondary aerosols. Additionally, organic molecular tracers were incorporated into PMF for source identification. …”
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Soluble Epoxide Hydrolase Inhibitor and 14,15-Epoxyeicosatrienoic Acid-Facilitated Long-Term Potentiation through cAMP and CaMKII in the Hippocampus by Han-Fang Wu, Yi-Ju Chen, Su-Zhen Wu, Chi-Wei Lee, I-Tuan Chen, Yi-Chao Lee, Chi-Chen Huang, Chung-Hsi Hsing, Chih-Wei Tang, Hui-Ching Lin

“…We found that pharmacological inhibition of sEH to stabilize endogenous EETs and exogenous 14,15-EET significantly increased the field excitatory postsynaptic potential (fEPSP) response in the CA1 area of the hippocampus, while additionally enhancing high-frequency stimulation- (HFS-) induced long-term potentiation (LTP) and forskolin- (FSK-) induced LTP. sEH inhibitor (sEHI) N-[1-(oxopropyl)-4-piperidinyl]-N’-[4-(trifluoromethoxy) phenyl)-urea (TPPU) and exogenous 14,15-EET increased HFS-LTP, which could be blocked by an N-methyl-D-aspartate (NMDA) receptor subunit NR2B antagonist. …”
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The effects of low-carbohydrate diet on glucose and lipid metabolism in overweight or obese patients with T2DM: a meta-analysis of randomized controlled trials by Wende Tian, Shuyu Cao, Yongxin Guan, Zihao Zhang, Qiyu Liu, Jianqing Ju, Ruixi Xi, Ruina Bai

“…Weight loss, reduced BMI, lower diastolic blood pressure, and decreased waist circumference were additional benefits.ConclusionLow-carbohydrate diets may enhance glycemic control and lipid profiles in overweight or obese T2DM patients, warranting consideration in T2DM management. …”
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Characterization of microbial communities in flavors and fragrances during storage by Yingjie Feng, Tingting Zhang, Jinchu Yang, Wenzhao Liu, Yongfeng Yang, Jihong Huang, Shen Huang, Zongcan Yang, Qianjin Liu, Wenchao Zheng, Qing Zhou, Qing Zhou

“…Throughout the storage process, Zygosaccharomyces and its dominant species, Zygosaccharomyces bailii, remained prevalent, though their average relative abundance decreased from 81.26 to 32.29%. In addition, the bacterial species Oceanobacillus sojae and Niallia nealsonii showed significant increases in relative abundance, suggesting that bacteria were one of the key contributors to the spoilage of flavors and fragrances. …”
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Medialization of shaft of humerus to provide medial buttress and prevent varus collapse in 3- and 4-part proximal humerus fractures: review of the surgical technique by Srinivas Kasha, MS(Ortho), Ranjith Kumar Yalamanchili, MS(Ortho), G.P.R.K. Rohit, MS(Ortho), Suresh Krishna Lokayah, MS(Ortho), Varun Kulkarni, MBBS

“…Conclusion: Despite limitations, this technique offers a biomechanically sound approach to enhance fixation stability, potentially improving the outcomes in proximal humerus fractures without the need for any additional fibular grafting procedures.…”
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Increasing stress resilience in older adults through a 6-week prevention program: effects on coping strategies, anxiety symptoms, and cortisol levels by Marie-Josée Richer, Sébastien Grenier, Sébastien Grenier, Sonia Lupien, Sonia Lupien, Pierrich Plusquellec, Pierrich Plusquellec, Pierrich Plusquellec

“…Few studies have evaluated stress management training (SMT) interventions based on psychoneuroendocrinology that were designed to be delivered to healthy older adults in community settings.MethodsIn this study, a total of 170 older adults (mean age = 76.07, SD = 7.67) participated in a cluster-randomized trial designed to compare the delivery of an SMT intervention with a waitlist condition.ResultsThe effect of SMT on coping strategies, stress, anxiety, and depression was measured 3 weeks and 3 months after the intervention. In addition, we tested the effect on basal cortisol secretion over 2 days from saliva samples upon awakening and the total diurnal cortisol output [area under the curve with respect to ground (AUCg)]. …”
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Accumulation Mechanism of Marine Shale Gas Reservoir in Anticlines: A Case Study of the Southern Sichuan Basin and Xiuwu Basin in the Yangtze Region by Kun Zhang, Yan Song, Shu Jiang, Zhenxue Jiang, Chengzao Jia, Yizhou Huang, Ming Wen, Weiwei Liu, Pengfei Wang, Xin Li, Tianlin Liu, Xuelian Xie, Chang’an Shan, Xiaoxue Liu, Xin Wang

“…Under the condition of both anticlines and contiguous synclines, shale gas escapes through fractures resulting from extrusion along the anticline and the uplift effect. In addition, driven by differences in the formation pressure coefficients, shale gas is capable of migrating in a short-distance stair-type style from synclines to the adjacent anticlines. …”
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Tear film lipid layer thickness and blink dynamics in patients with blepharospasm by Ji-Sun Paik, Min Jeong Kwon, Ga Hee Nam, Kyungdo Han, Woong-Joo Whang, Ho Sik Hwang, Suk-Woo Yang, Hyun-Seung Kim, Kyung Sun Na, Won-Kyung Cho

“…Abstract Background This study investigates the effect of botulinum toxin A on lipid layer thickness (LLT) and blink dynamics in patients with benign essential blepharospasm (BEB) compared to dry eye disease (DED) patients. Methods We reviewed the medical records of patients with dry eye disease (DED) and BEB treated with botulinum toxin A (BoT A) injections. …”
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Long-term maintenance of patient-specific characteristics in tumoroids from six cancer indications by Colin D. Paul, Chris Yankaskas, Pradip Shahi Thakuri, Brittany Balhouse, Shyanne Salen, Amber Bullock, Sylvia Beam, Anthony Chatman, Sybelle Djikeng, Xiaoyu Jenny Yang, Garrett Wong, Isha Dey, Spencer Holmes, Abigail Dockey, Lindsay Bailey-Steinitz, Lina Zheng, Weizhong Li, Vivek Chandra, Jakhan Nguyen, Jason Sharp, Erik Willems, Mark Kennedy, Matthew R. Dallas, David Kuninger

“…Previously established tumoroid lines were also transitioned to OncoPro medium and exhibited, on average, similar growth rates and conserved donor-specific characteristics when compared to original media systems. Additionally, OncoPro medium was compatible with both embedded culture in extracellular matrix and growth in a suspension format for facile culture and scale up. …”
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H-NS controls the susceptibility of Escherichia coli to aminoglycosides by interfering its uptake and efflux by Qiuru Chen, Yulei Liang, Yanbin Dong, Junling Cui, Kun He, Xiaoyuan Ma, Jinfeng Zhao, Jinfeng Zhao, Yajun Zhai, Yajun Zhai, Li Yuan, Li Yuan, Li Yuan, Li Yuan

“…Meanwhile, hns deletion also led to remarkable inhibition of the efflux pumps activity and decreased expressions of efflux-related genes clbM, acrA, acrB, acrD, and emrE, which reduced the efflux of aminoglycosides. In addition, the activation of glycolysis and electron transport chain, as well as the reduction of Δψ dissipation, could lead to a remarkable increase in proton motive force (PMF), thus further inducing more aminoglycosides uptake by strain EΔhns. …”
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The quality and technological parameters of milk obtained from dairy cows with subclinical mastitis by Magdalena Zalewska, Paulina Brzozowska, Magdalena Rzewuska, Ewelina Kawecka-Grochocka, Daria M. Urbańska, Tomasz Sakowski, Emilia Bagnicka

“…Bacterial contamination did not appear to significantly affect the yield of milk or its main components, namely protein, casein, lactose, fat, TS, solid nonfat, free fatty acid, or citric acid. …”
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DOCK4 Is a Platinum-Chemosensitive and Prognostic-Related Biomarker in Ovarian Cancer by Qianqian Zhao, Jie Zhong, Ping Lu, Xiao Feng, Ying Han, Chenqi Ling, Wenke Guo, Weijin Zhou, Fudong Yu

“…We further found that there were significant correlations between DOCK4 expression and the levels of CD4+ T cell infiltration, dendritic cell infiltration, and neutrophil infiltration in OV. In addition, we verified the expression level of DOCK4 in OV cell lines treated with platinum drugs and found that DOCK4 is potentially responsive to platinum drugs. …”
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ALMA Spectral Survey of an Eruptive Young Star, V883 Ori (ASSAY). II. Freshly Sublimated Complex Organic Molecules in the Keplerian Disk by Jae-Hong Jeong, Jeong-Eun Lee, Seonjae Lee, Giseon Baek, Ji-Hyun Kang, Seokho Lee, Chul-Hwan Kim, Hyeong-Sik Yun, Yuri Aikawa, Gregory J. Herczeg, Doug Johnstone, Lucas Cieza

“…This may indicate the planet-forming material chemically evolves in the disk midplane after being accreted from the envelope. In addition, as found in the comet 67P/Churyumov-Gerasimenko, nitrogen might also be trapped as ammonium salt within the dust grains in the V883 Ori disk.…”
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Archival Research, Underwater Optical Surveys, and 3D Modelling: Three Stages for Shaping the Wreck of the Steamship <i>Bengala</i> (Isola di Capo Rizzuto, Crotone, Italy) by Salvatore Medaglia, Fabio Bruno, Ana Castelli, Matteo Collina, Barbara Davidde Petriaggi, Luca De Rosa, Julieta Frere, Fabrizio Fuoco, Guillermo Gutiérrez, Antonio Lagudi, Francesco Megna, Raffaele Peluso

“…The model can be used in augmented reality (AR) applications to enhance underwater exploration, allowing divers to visualise the reconstructed ship in its original environment. Additionally, it supports museum exhibits, interactive visualisations, and educational games, making it a valuable resource for engaging the public with maritime history and archaeology.…”
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Ramadan during pregnancy and the role of dietary intake for neonatal health in Kaduna, Northwestern Nigeria: a cross-sectional study by Musa Abubakar Kana, Bilkisu Usman, Amina Mohammed-Durosinlorun, Jennifer Ahmed, Hassana Habiba Abubakar, Yakub Abdulmalik, Fabienne Pradella

“…With more than 25% of the global population adhering to Islam, this study highlights the need for additional research on Ramadan during pregnancy across different settings.…”
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A meta-core outcome set for stillbirth prevention and bereavement care following stillbirth in LMIC by Jamie J Kirkham, Declan Devane, Carol Bedwell, Tina Lavender, Tracey A Mills, Sabina Wakasiaka, Rose Laisser, Bellington Vwalika, Nasim Chaudhry, Angela Chimwaza, Elizabeth Ombeva Ayebare, Sudhindrashayana Fattepur, Tayyeba Kiran, Kushupika Dube, Farai Marenga, Idesi Chilinda, Unice Goshomi, Allen Nabisere, Zaib Un Nisa

“…For bereavement care following a stillbirth, five core outcomes reached a consensus, which included outcomes related to labour and birth, a postpartum complication, care experience, mental health and emotional and social well-being.Discussion These COS will improve the consistency of outcomes for future research in an LMIC setting. Additionally, they will complement existing COS for stillbirth prevention and bereavement care developed in high-income settings. …”
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Between-Subject and Within-Subject Variation of Muscle Atrophy and Bone Loss in Response to Experimental Bed Rest by Jonas Böcker, Marie-Therese Schmitz, Marie-Therese Schmitz, Uwe Mittag, Jens Jordan, Jens Jordan, Jörn Rittweger, Jörn Rittweger

“…These results demonstrate the existence of substantial bone BSV, and that it is partly driven by WSV, and likely also by physical activity and dietary habits prior to bed rest. In addition, genetic and epigenetic variation could potentially explain BSV, but not WSV. …”
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Lyme disease associated neurological and musculoskeletal symptoms: A systematic review and meta-analysis by Ganesh Bushi, Ashok Kumar Balaraman, Shilpa Gaidhane, Suhas Ballal, Sanjay Kumar, Mahakshit Bhat, Shilpa Sharma, M Ravi Kumar, Aashna Sinha, Mahalaqua Nazli Khatib, Nishant Rai, Sanjit Sah, Ambanna Yappalparvi, Shailesh Kumar Samal, Doddolla Lingamaiah, Muhammed Shabil

“…Although heterogeneity across the studies was high, sensitivity analysis confirmed the consistency of our findings. Additionally, there was evidence of publication bias. …”
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Assisted Egg White Biogenic Synthesis for Elaboration of ZnO Nanoparticles by Elena Andreea Vijan, Ecaterina Magdalena Modan, Sorin Georgian Moga, Denis Aurelian Negrea, Adriana-Gabriela Schiopu, Mihai Oproescu, Daniela Istrate

“…These biomolecules interact with metal ions, leading to the reduction and nucleation of nanoparticles. Additionally, the proteins in egg white act as capping agents, stabilizing the nanoparticles and preventing their aggregation. …”
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FMT reduces systemic inflammatory response in severe acute pancreatitis by increasing the abundance of intestinal Bifidobacteria and fecal bacteria by Yanning Mao, Yandong Huang, Weiwei Zhang, Huiping Liang, Fengming Liu, Qi Luo, Chunqin Xu, Yi Qin, Jiawen Liu, Shaobo Tang, Huaying Liu, Xiaolong Ge

“…Receiver operating characteristic (ROC) curve analysis indicated that Bifidobacterium longum might play a critical role in the efficacy of FMT, with an area under the curve (AUC) value of 0.84. Additionally, there was a negative correlation between Bifidobacterium longum abundance and procalcitonin (PCT) levels, as well as a negative correlation between Escherichia coli abundance and both CT and Ca values (P < 0.05). …”
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