Multicenter Study of the Hemorrhage Risk after Endoscopic Mucosal Resection Associated with Direct Oral Anticoagulants by Ritsu Yasuda, Naohisa Yoshida, Takaaki Murakami, Ryohei Hirose, Ken Inoue, Osamu Dohi, Yuji Naito, Yutaka Inada, Takashi Okuda, Daisuke Hasegawa, Kotaro Okuda, Kiyoshi Ogiso, Yoshikazu Inagaki, Koichi Soga, Akira Tomie, Yoshito Itoh

“…There were no significant differences in the rates of POH based on the type of DOAC. In addition, no thromboembolisms occurred due to stopping of DOAC treatment. …”
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Comparison of tissue-based and plasma-based testing for mutation in non–small cell lung cancer patients by Yoon Kyung Kang, Dong Hoon Shin, Joon Young Park, Chung Su Hwang, Hyun Jung Lee, Jung Hee Lee, Jee Yeon Kim, JooYoung Na

“…Background Epidermal growth factor receptor (EGFR) gene mutation testing is crucial for the administration of tyrosine kinase inhibitors to treat non–small cell lung cancer. In addition to traditional tissue-based tests, liquid biopsies using plasma are increasingly utilized, particularly for detecting T790M mutations. …”
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<i>In vitro</i> assay of biological activity of a national preparation of macrophage activating factor (GcMAF-RF) by E. V. Levites, S. S. Kirikovich, E. V. Dolgova, A. S. Proskurina, G. S. Ritter, А. A. Ostanin, E. R. Chernykh, S. S. Bogachev

“…The preparation will be in demand in the field of cancer treatment, and, in addition, it can be used in the treatment of a number of neurodegenerative pathologies.…”
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Pedobarographic Measurements of Rheumatoid Feet Compared with Clinical Parameters by Yasemin YUMUSAKHUYLU, Bilinc DOGRUOZ KARATEKIN, Selin TURAN TURGUT, Afitap ICAGASIOGLU, Esra SELIMOGLU, Sadiye MURAT, Esen KASAPOGLU, Bekir TURGUT

“…Rheumatoid feet investigation showed that foot involvement is independent of the disease duration, whereas midfoot plantar pressures are associated with the body mass index. Additionally, DAS28 may fall short as a marker of disease activity because it neglects foot problems.…”
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Patterns and Drivers of Surface Energy Flux in the Alpine Meadow Ecosystem in the Qilian Mountains, Northwest China by Yongxin Tian, Zhangwen Liu, Yanwei Fan, Yongyuan Li, Hu Tao, Chuntan Han, Xinmao Ao, Rensheng Chen

“…Results show that <i>R_n</i> is the main driver of both <i>H</i> and <i>LE</i>, highlighting its crucial role in turbulent flux variations. Additionally, a negative correlation was found between air temperature and <i>H</i>, suggesting that high temperatures may suppress <i>H</i>. …”
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Urea coated with cellulose acetate-lignin composite presents lower loss by ammonia volatilization by Jhonatan Nolasco Nascimento, Letícia Said Marangon, Fabiane Carvalho Ballotin, Renê Chagas da Silva, José Mauro de Almeida, Edison Márcio Mattiello, Reinaldo Bertola Cantarutti, Deusanilde de Jesus Silva

“…Film-forming solutions (Fs) were produced by combining Lig (0.3, 0.6, 0.9, and 1.2 %, w/w, based on Ac), and Ac (2 %, w/w, based on urea). In addition, two reference treatments were included: urea without coating (U) and urea coated only with Ac. …”
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Macroscopic and microscopic characteristics of nanosilica sol-based composite grout in sealing fractured argillaceous rock: A comparative study with silica sol and cement slurry by Zhe Xiang, Nong Zhang, Dongjiang Pan, Zhengzheng Xie, Peng Wang, Dongxu Liang

“…Additionally, the paper compares the performance of this composite grout with traditional silica sol and cement grout, providing initial insights into the anti-seepage reinforcement mechanism of the composite grout when used in grouting argillaceous soft rock. …”
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Does preeclampsia impact the gut microbiota of preterm offspring during early infancy? by Yang Chen, Zhou-Ting Yi, Hai-Long Yu, Xiao-Yan Wu, Jun-Ping Wang, Chuan Nie, Hui Li, Sheng-Hui Li, Qiu-Long Yan, Tian-Wen He, Min-Chai Chen, Xin-Yue Yang, Ji-Ying Wen, Li-Juan Lv

“…These findings underscore the substantial influence of maternal health on the early development of the neonatal gut microbiota and highlight the potential long-term health consequences. Additionally, the differences in metabolic pathways further emphasize the impact of preeclampsia on gut microbiota functionality.…”
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Table for two: Diet composition differences of allopatric and sympatric populations of island geckos by Catarina J. Pinho, Bárbara Santos, Vanessa A. Mata, Ricardo J. Lopes, Maria M. Romeiras, Evandro P. Lopes, Paulo C. Alves, Brent C. Emerson, Raquel Vasconcelos

“…These results suggest that competition has played an important role in structuring the stable coexistence of these species in sympatry, promoting extreme morphological discrepancies that allowed resource partitioning. In addition, this study reveals unexpected dietary differences within the allopatric population of T. raziana on Santa Luzia, suggesting a niche shift in response to the absence of a direct competitor that may influence the reintroduction planning of T. gigas. …”
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Application of photogrammetry and laser scanner on the Bronze Age structures of the Castillejos de Luna cist tomb necropolis (Pizarra, Spain) by Alejandro Muñoz-Muñoz, Diego Fernández-Sánchez, Eduardo Vijande-Vila, Serafín Becerra-Martín, Juan Jesús Cantillo-Duarte, Salvador Domínguez-Bella, Virgilio Martínez Enamorado, Francisca Rengel Castro, Pedro Cantalejo Duarte, María del Mar Espejo-Herrerías, José Suárez-Padilla, Juan Antonio Martín-Ruiz, José Ramos-Muñoz

“…The results shown here are of metric character, with orientation and geographical location of the structures. In addition, in one of the tombs the authors show the combination of photogrammetric techniques with laser scanners to obtain a single high-resolution 3D model; subsequently a retopology process is carried out to achieve a "light" model with a photorealistic appearance that is both easily manipulated on mobile devices for its dissemination and a guarantee that the general public can enjoy this necropolis in a different way. …”
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Exploring the clinical significance of anti-acetylcholine receptor antibody titers, changes, and change rates in Myasthenia Gravis by Lijun Luo, Xinyi Zhu, Chunbei Wen, Yifan Guo, Jie Yang, Dongsheng Wei, Ping Yu, Mei Wan

“…Pearson and Spearman correlation analyses were used to study the relationships between changes in AChR-Ab titers, rates of change, and MG scores.Results(1) At baseline, there was no correlation between AChR-Ab titers and age, duration of illness, gender, MGFA classification, or presence of thymic abnormalities. (2) The trend of decreasing AChR-Ab titers matched the trend of reduced QMGS and ADL scores. (3) Six months into treatment,there was a correlation between AChR-Ab titer changes and changes in ADL scores. (4) Three months into treatment, RR-AChRAb showed a correlation with the rate of change in ADL at the same time point.ConclusionWe found the trend of decreased AChR-Ab titers after standardized treatment that was consistent with reductions in QMGS and ADL scores. Additionally, the rate of change in AChR-Ab titers at 3 months and the change in AChR-Ab titers at 6 months into treatment did reflect improvements in activities of daily living for MG patients.…”
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Uncovering potential causal genes for undiagnosed congenital anomalies using an in-house pipeline for trio-based whole-genome sequencing by Jeong-Min Kim, Hye-Won Cho, Dong Mun Shin, Oc-Hee Kim, Jihyun Kim, Hyeji Lee, Gang-Hee Lee, Joon-Yong An, Misun Yang, Heui Seung Jo, Ja-Hyun Jang, Yun Sil Chang, Hyun-Young Park, Mi-Hyun Park

“…Finally, functional validation of six genes including RYR3, NRXN1, FREM2, CSMD1, RARS1, and NOTCH1, revealed various phenotypes in zebrafish models that aligned with those observed in each patient. In addition to the above findings, eleven diagnostic variants initially discovered in a targeted-gene analysis from a previous study were also identified as diagnostic variants and the in-house pipeline demonstrated a significant advantage in accurately and efficiently identifying de novo variants (DNVs), compound heterozygous (CH), and homozygous variants. …”
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Abundance, occurrence, and degradation of airborne antibiotic resistance genes in coastal and marine atmospheres by Shijie Jia, Shijie Jia, Xiaohong Yao, Jianhua Qi, Jianhua Qi, Xiaohuan Liu, Xiaohuan Liu, Huiwang Gao, Huiwang Gao

“…The inconsistent trend suggested that the reduction in airborne ARGs was greater than their increase with bacterial reproduction during their accumulation and transport in the atmosphere. In addition, the number of ARG types in marine aerosols was greater than that in coastal aerosols. …”
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Decreased expression of miR-200a and miR-223-3p in endometriosis during the secretory phase of menstrual cycle: Insights from a case-control study on molecular biomarkers and disea... by Yasaman Nazari Hagh, Mohamadreza Ahmadifard, Sedigheh Esmaelzadeh, Soheila Abbaszadeh, Naser Shokrzadeh

“…Results: Histological analysis confirmed that both groups were in the secretory stage. Additionally, miRNA expression results showed a significant decrease in the miR-200a and miR-223-3p expression levels in EM group compared to control group. …”
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Factors associated with girl child marriage in Iran: a qualitative socio-ecological approach by Asma Pourtaheri, Mehrsadat Mahdizadeh, Mehrsadat Mahdizadeh, Hadi Tehrani, Hadi Tehrani, Jamshid Jamali, Jamshid Jamali, Nooshin Peyman, Nooshin Peyman

“…Consequently, the management, control, and prevention of Girl child marriage necessitate comprehensive efforts at regional, national, and international levels. In addition to creating platforms for the empowerment of girls at both national and regional levels, international policies can also foster a supportive environment.…”
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MCU complex: Exploring emerging targets and mechanisms of mitochondrial physiology and pathology by Jin Wang, Jinyong Jiang, Haoliang Hu, Linxi Chen

“…Aim of review: This article provides an in-depth analysis of the current research status of the MCU complex, focusing on its molecular composition, regulatory mechanisms, and association with diseases. In addition, we conducted an in-depth analysis of the regulatory effects of agonists, inhibitors, and traditional Chinese medicine (TCM) monomers on the MCU complex and their application prospects in disease treatment. …”
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The Modular and Integrated Data Assimilation System at Environment and Climate Change Canada (MIDAS v3.9.1) by M. Buehner, J.-F. Caron, E. Lapalme, A. Caya, P. Du, Y. Rochon, S. Skachko, M. Bani Shahabadi, S. Heilliette, M. Deshaies-Jacques, W. Chang, M. Sitwell

“…The software is designed to be sufficiently general to enable other DA applications, including atmospheric constituents (e.g. ozone), sea ice, and sea surface temperature. In addition to describing the current MIDAS applications, a sample of the results from these systems is presented to demonstrate their performance in comparison with either systems from before the switch to using MIDAS software or similar systems at other numerical weather prediction (NWP) centres. …”
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Foliar spraying with zinc oxide nanoparticles enhances the anti-osteoporotic efficacy of the fruit extracts of Silybum marianum L. by stimulating silybin production by Bedoor Fahad Almulhim, Fadia El Sherif, Fadia El Sherif, Nancy S. Younis, Yamen Safwat, Salah Khattab, Salah Khattab

“…The highest gains were observed in plants sprayed with the highest ZnO-NP concentration (20.0 mg/L). In addition, gene expression studies revealed that ZnO-NPs stimulated silybin (A+B) production by activating CHS genes. …”
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The effect of differences in the third domain of the glycoprotein E of tick-borne encephalitis virus of the Far Eastern, Siberian and European subtypes on the binding of recombinan... by I. K. Baykov, A. L. Matveev, L. A. Emelianova, G. B. Kaverina, S. E. Tkachev, N. V. Tikunova

“…At the same time, the affinity of ch14D5 antibody for similar D3 proteins derived from “Zausaev”, “1528-99” and “Absettarov” strains of the Siberian and European subtypes of TBEV was noticeably lower (KD= 25±4, 300±50, 250±50 nM, respectively). In addition, information about the spatial arrangement of amino acid residues that are different for the studied recombinant proteins indicates that the epitope recognized by the ch14D5 antibody is in close proximity to the lateral ridge of D3 domain of E glycoprotein.…”
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Elucidating stearoyl metabolism and NCOA4-mediated ferroptosis in gastric cancer liver metastasis through multi-omics single-cell integrative mendelian analysis: advancing personal... by Zhongqiu Yang, Yuquan Chen, Yaping Miao, Haisheng Yan, Kexin Chen, Yaoqin Xu, Lanqian Su, Lanyue Zhang, Yalan Yan, Hao Chi, Jin Fu, Lexin Wang

“…Conclusion This study enhances the understanding of the relationship between stearoyl metabolism and ferroptosis in promoting liver metastasis of gastric cancer and its role in the regulation of tumor heterogeneity. In addition, this study contributes to a deeper understanding of the dynamics of gastric cancer tumor microenvironment (TME) and provides a basis for the development of better interventions to combat cancer metastasis.…”
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