Nicotine is associated with smoking dependence and vascular inflammation through cotinine: A mediation analysis by Kumboyono Kumboyono, Indah N. Chomsy, Nadya N. Shalshabilla, Hidayat Sujuti, Arie Srihardyastutie, Cholid T. Tjahjono, Teuku Heriansyah, Titin A. Wihastuti

“…The study indicates an emerging cycle regarding nicotine–cotinine consumption and nAChRs expression. In addition, the data in this study showed a significant relationship (p<0.001) regarding the cycle formed with decreased NO levels as a result of damage caused by Tie2-mediated inflammation. …”
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Patient‐derived acellular ascites fluid affects drug responses in ovarian cancer cell lines through the activation of key signalling pathways by Katharina Bischof, Andrea Cremaschi, Lena Eroukhmanoff, Johannes Landskron, Lise‐Lotte Flage‐Larsen, Alexandra Gade, Line Bjørge, Alfonso Urbanucci, Kjetil Taskén

“…Through in vitro testing of drug sensitivity and by assessing intracellular phosphorylation status in response to mono‐ and combination treatment of five EOC cell lines after incubation with AAFs derived from 20 different patients, we investigated the chemoresistance‐inducing potential of ascites. We show that the addition of AAFs to the culture media of EOC cell lines has the potential to induce resistance to standard‐of‐care drugs (SCDs). …”
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Multi-metal mixture exposure and cognitive function in urban older adults: The mediation effects of thyroid hormones by Zhuoqi Zhu, Juanhua Li, Yang Peng, Ning Qin, Jiemei Li, Ying Wei, Biwen Wang, Yunfei Liao, Huaicai Zeng, Lu Cheng, Han Li

“…Mixed exposure to Mo and Rb was linked to an increased risk of cognitive impairment. Additionally, levels of TSH, FT4 and TT4 were associated with cognitive function, mediating the effects of Rb, Zn and Cu on cognitive function.…”
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The impact of the COVID-19 pandemic on HIV testing in Peru: an interrupted time series analysis from 2014 to 2022 by Robinson A. Yrene-Cubas, Jesus Perez-Castilla, Daniel E. Reynaga-Cottle, Maria José Bringas, David R. Soriano-Moreno, Daniel Fernandez-Guzman, Jose A. Gonzales-Zamora

“…Statistical analysis involved segmented regression with Newey-West standard errors, dividing each year of evaluation into four quarters. Additionally, we applied an Autoregressive Integrated Moving Average (ARIMA) model. …”
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Co-obligate symbioses have repeatedly evolved across aphids, but partner identity and nutritional contributions vary across lineages by Manzano-Marín, Alejandro, Coeur d’acier, Armelle, Clamens, Anne-Laure, Cruaud, Corinne, Barbe, Valérie, Jousselin, Emmanuelle

“…However, in two lineages, Buchnera has lost some essential symbiotic functions and is now complemented by additional symbionts. Though these cases break our view of aphids harbouring a single obligate endosymbiont, we know little about the extent, nature, and evolution of these associations across aphid subfamilies. …”
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Advancement of Pt and Pd-based catalysis for green, sustainable energy and bio-medical applications by Nithyadharseni Palaniyandy, Sekhosana Kutloano, Lakshmi Devaraj, Xolile Fuku, Sathish Sundar Dhilip Kumar

“…Further, the antimicrobial properties of Pt and Pd nanoparticles are explored, showcasing their potent inhibition of bacterial growth, disruption of biofilm formation, and effectiveness against multidrug-resistant bacteria. Additionally, the unique attributes of metal nanoclusters for biomedical sensing and imaging applications are discussed. …”
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A Fully Coupled Hydromechanical Model for CO2 Sequestration in Coal Seam: the Roles of Multiphase Flow and Gas Dynamic Diffusion on Fluid Transfer and Coal Behavior by Rui Yang, Weiqun Liu, Tianran Ma, Junhe Xie, Yang Hu, Rui Zhou, Yongjie Yang

“…Subsequently, all the mentioned mechanisms and interactions were embedded into the coupled hydromechanical model, and this new fully coupled model was well verified by a set of experimental data. Additionally, through the model application for long-term CO2 sequestration, we found that the stored CO2 molecules are mainly in an adsorbed state at the early injection stage, while with the continuous injection of gas, the stored CO2 molecules are mainly in a free state. …”
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Emission Characteristics and Health Risk Assessment of Volatile Organic Compounds in Key Industries: A Case Study in the Central Plains of China by Fengwei Liu, Lei Tong, Qingyue Luo, Yufei Ling, Hongyi Gu, Yangchao Lv, Anwei Shi, Hui Liu, Hang Xiao, Cenyan Huang

“…The concentration of total VOCs emitted from the eight industries in order from large to small was as follows: packaging and printing > pharmaceutical > paint manufacturing > industrial coating > chemical industry > metal smelting > furniture manufacturing > textile printing and dyeing. In addition to industrial coating, the total VOCs and their corresponding ozone formation potential of organized emissions in seven industries (1.44–87.64, 1.52–181.61 mg/m³) were higher than those of unorganized emissions (0.38–24.17, 0.38–125.55 mg/m³). …”
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Thermodynamic qualification of knitted spacer fabrics for use as insulation box insert in the context of refrigerated transport containers in the logistics sector by Julia Klausmann, Thomas Mutschler, Prisca Holderied, Dominik Güther, Thomas Freitag, Matthias Hummel, Martin Zeitler, Oliver van Neerven, Marcus Oliver Weber, Christof Breckenfelder

“…Known refrigeration concepts are designed to cool the entire cargo hold. In addition, the goods cannot be removed from the vehicle while maintaining the cold chain. …”
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Effects of Artemisia argyi leaf water extract (AWE) on growth performance, muscle quality, intestinal microbial, and metabolomics of common carp (Cyprinus carpio) by Di Sun, Nanyang Zeng, Yingjia Pan, Qingsong Shu, Jixing Zou, Yingshi Huang, Guoxia Wang, Jun Shi

“…Notably, treatment with A1 significantly enhanced the growth performance of carp while increasing body fat content and reducing protein levels (p < 0.05). …”
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Influence of bleaching gels containing 45S5 Bioglass on enamel color, surface roughness, and microhardness by Rafael Dascanio, Camila Siqueira Silva Coelho, Marina Trevelin Souza, Edgar Dutra Zanotto, Vanessa Cavalli

“…At T2, 10%BG displayed a lower %SHL than 0%BG and PC, and all BG-containing groups showed a lower %SHL than PC (p < 0.05). The addition of BG did not influence the whitening efficacy of HP and did not change enamel roughness. …”
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Arbuscular mycorrhizal colonization defines root ecological strategies in an extreme arid environment by Cristian A. Delpiano, Cristian A. Delpiano, Cristian A. Delpiano, Rodrigo S. Rios, Rodrigo S. Rios, Rodrigo S. Rios, Claudia E. Barraza-Zepeda, Melissa J. Pozo, Lorgio E. Aguilera, Andrea P. Loayza, Andrea P. Loayza, Andrea P. Loayza

“…We found that larger RD correlated with higher levels of colM, supporting the ‘outsourcing’ strategy within the ‘collaboration gradient’ hypothesis of the RES. Additionally, RD and colM emerged as playing key roles in defining both dimensions of root ecological strategies. …”
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Hydrate-Based Methane Storage in Biodegradable Hydrogels Absorbing Dilute Sodium P-Styrenesulfonate Solution by Fangzheng Hua, Kang Tan, Jingyu Lv, Fei Wang, Mengting Sun

“…In this binary reaction system, the large surface area of hydrogels provided hydrate formation with sufficient nucleation sites and an enlarged gas–liquid interface, and in the meantime, the dilute SS solution produced an adequate capillary effect, which together enhanced mass transfer and accelerated hydrate formation kinetics. Additionally, the hybrid medium could relieve wall-climbing hydrate growth and improve poor hydrate compactness resulting from the bulk SS promoter. …”
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The intestinal microbial community and function of Riptortus pedestris at different developmental stages and its effects on development by Yanbin Wang, Rong Li, Chunjing Wang, Ting Sun, Hongjuan Zhang, Fang Zhao, Jiehui Liu, Yuqiong Hao, Xiansheng Xie

“…The gut bacteria have the stage specificity, indicating their function in the development of R. pedestris.ResultsEnterococcus and Caballerronia were the predominant bacteria present during the development of the 2 N–FAs. In addition, the microbial abundances in the 3 N and 4 N guts were significantly greater than those in the others guts. …”
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Phenotypic and WGS-derived antibiotic resistance patterns of Salmonella Enteritidis isolates from retail meat and environment during 2014 to 2019 in China by Liya Zheng, Qiannan Di, Xuebin Xu, Liyuan Liu, Chunbo Qu, Phil Bremer, Phil Bremer, Xiujuan Zhou

“…Notably, three isolates in cluster B require special mention: a monophasic strain resistant to eight antibiotics, a strain exhibiting highly heteroresistance, and a strain with additional exotoxin genes. These results highlight the importance of ongoing surveillance and the utility of WGS to track and understand antibiotic resistance in Salmonella Enteritidis.…”
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Dual Mechanisms of Action: Anti-Candida and Anti-Inflammatory Potential of <i>Lactobacillus</i> Fermentation Broth in Treating Vulvovaginal Candidiasis by Huann-Cheng Horng, Jin-Wei Xu, Yi-Shan Kuo, Yu-Sin Chen, Yu-Hsuan Chiu, Kuan-Hao Tsui, Yu-Tang Tung

“…Our findings revealed that VAGINNE^® treatment enhanced the growth of beneficial <i>Lactobacillus</i> species while suppressing <i>C. albicans</i> proliferation, leading to a more balanced vaginal microbiome. Additionally, VAGINNE^® significantly reduced pro-inflammatory cytokines (IL-17A, IL-22, IL-23) in vaginal tissues and systemic inflammatory markers (IL-6, IL-1β) in plasma. …”
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3D modeling to predict vascular involvement in resectable pancreatic adenocarcinoma by Sguinzi R, Vidal J, Poroes F, Bartolucci DA, Litchinko A, Gossin E, Fingerhut A, Toso C, Buhler L, Egger B

“…Conclusions: Our pilot study demonstrates that 3D segmentation can provide additional information for choosing the best treatment strategy and surgical plain in patients with BR-PDAC. …”
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Stabilization of metal-doped magnesium oxide nanoparticles with PAMAM dendrimers to improve alpha-amylase enzyme inhibition by Jaison Jeevanandam, Mara Gonçalves, Rita Castro, Juan Gallo, Manuel Bañobre-López, João Rodrigues

“…The results showed that the addition of dopants led to smaller, more stable, and slightly monodispersed spherical, hexagonal, and elongated hexagonal/rod-shaped MgO nanoparticles. …”
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Genomic variation responding to artificial selection on different lines of Pekin duck by Xinye Zhang, Fangxi Yang, Jinxin Zhang, Tao Zhu, Xiurong Zhao, Yuchen Liu, Junhui Wen, Hongchang Gu, Gang Wang, Xufang Ren, Anqi Chen, Lujiang Qu

“…By the analysis of the selection signal, strong selection characteristics in certain genomic regions during the breeding of Peking duck across different selected lines were observed. In addition, copy number variations (CNVs) in Pekin duck populations were analyzed. …”
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Integrated SegFlow, µSIA, and UPLC for Online Sialic Acid Quantitation of Glycoproteins Directly from Bioreactors by Letha Chemmalil, Tanmay Kulkarni, Mathura Raman, Priya Singh, Yueming Qian, Chris Chumsae, Kyle McHugh, Zhuangrong Huang, Eric Hodgman, Michael C. Borys, Julia Ding, Gloria Li, Anthony Leone

“…Recent studies have demonstrated that sialylation of O‐linked glycan plays a role in protecting against macrophage galactose lectin (MGL)‐mediated clearance. In addition to the impact on serum half‐life, sialylation can influence other clinical outcomes, including immunogenicity, potency, and cytotoxicity. …”
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