Can Caffeine Be an Effective Ergogenic Aid in Combat Sports? A Comprehensive Review by Marcin Komorowski, Michał Janiszewski, Aleksandra Pelczarska, Rafal Kaczorowski, Tomasz Forenc, Jaromir Hunia, Julia Górny, Jonasz Jurek, Alicja Kapciak

“…Aim of Study: The primary aim of this study is to analyze the effects of caffeine on performance in combat sports, considering various factors such as optimal dosage, timing, and the impact of habitual caffeine consumption. Additionally, this paper evaluates the potential adverse effects, including anxiety, sleep disturbances, and cardiovascular concerns, as well as the considerations regarding caffeine’s status as a banned substance in sports. …”
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Multiple Episodes of Remote Brightenings Driven by a Coronal Extreme-ultraviolet Jet on the Sun by Chao Zhang, Zhenghua Huang, Hengyuan Wei, Youqian Qi, Mijie Shi, Hui Fu, Xiuhui Zuo, Weixin Liu, Mingzhe Sun, Ming Xiong, Lidong Xia

“…Besides the flows of the ejecta, we have identified two additional flows originating from the eruption site. …”
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A comprehensive review on the plant sources, pharmacological activities and pharmacokinetic characteristics of Syringaresinol by Lei Zhang, Yuqing Tian, Lingling Zhang, Huanyu Zhang, Jinghua Yang, Yi Wang, Na Lu, Wei Guo, Liang Wang

“…This study aims to provide a comprehensive overview of Syringaresinol on its sources and biological activities to provide insights into its therapeutic potential, and to provide a basis for high-quality studies to determine the clinical efficacy of this compound. Additionally, we explored the pharmacokinetics, toxicology, and drug development aspects of Syringaresinol to guide future research efforts. …”
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Estimating the global cost of vision impairment and its major causes: protocol for a systematic review by Nathan Congdon, Thomas Butt, Peng Tee Khaw, Andrew Bastawrous, Tasanee Braithwaite, Rupert R A Bourne, Matthew J Burton, Serge Resnikoff, Jacqueline Ramke, Kevin Frick, Hugh Taylor, Iris Gordon, Ana Patricia Marques, John Cairns, Justine H Zhang, Hannah B Faal, Iain Jones, Marty Jovic, Allyala Nandakumar

“…No language or geographical restriction will be applied. Additional literature will be identified by reviewing the references in the included studies and by contacting field experts. …”
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Abnormal expression of miR-668-3p in non-small cell lung cancer patients and its correlation with serum-related tumor markers by Wen Yang, Ling Liu, Jianliang Li, Yingchao Liu, Lin Rong, Junjie Ma, Rongchen Li, Qiuyue Zhang, Yugang Liu

“…The ROC curve analysis was conducted to determine the individual and combined diagnostic efficacy of miR-668-3p and serum biomarkers. Additionally, a logistic regression model was utilized to identify risk factors for lung cancer in patients with pulmonary tuberculosis. …”
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The stability of soil aggregates in sweet cherry (Prunus avium L.) orchards of different ages and varieties by Muhao Chen, Shu Feng, Jun Wang, Mingyu Gao, Min Liu, Kaibo Wang, Zhou-ping Shangguan, Yongwang Zhang

“…Principal component analysis indicated that soil quality deteriorated increasingly with ages, while pass-through analysis demonstrated that ages and soil aggregate stability were key factors influencing soil quality. In conclusion, in addition to economic benefits, soil quality should also be protected. …”
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Short-term effects of follicle-stimulating hormone on immune function, lipid, and vitamin metabolism in transiently castrated men by Jéssica Guedes, Indira Pla, Aniel Sanchez, Gyorgy Marko-Varga, Gilberto Barbosa Domont, K Barbara Sahlin, Berk Hazir, Aleksander Giwercman, Fábio César Sousa Nogueira, Johan Malm, Yvonne Lundberg Giwercman

“…Results: FSH significantly upregulates key proteins involved in the modulation of inflammatory response and innate immune system (P ≤ 0.03) and dysregulates lipid metabolism, evidenced by downregulation of multiple apolipoproteins (P ≤ 0.04) and increased levels of cholesterol and glycerophospholipids (P ≤ 0.03). In addition, low FSH levels were correlated with a reduction in the active form of vitamin D (P < 0.02). …”
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Identification of QTL for Pre-harvest Sprouting Resistance by Using Chromosome Segment Substitution Lines of Dongxiang Common Wild Rice by Jiaxiao HU, Jin LIU, Xiaoding MA, Hang TU, Huiying ZHOU, Bingxin MENG, Di CUI, Maomao LI, Longzhi HAN, Liqin YU

“…These QTLs formed four QTL clusters (qPHSRC1, qPHSRC2, qPHSRC8 and qPHSRC9), among which qPHSRC2 and qPHSRC9 had higher LOD values, phenotypic contribution rate (%) and additive effect, and qPHSRC2 was a newly discovered major QTL cluster.…”
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Nursing of a patient with post-stroke constipation of Qi-deficiency type treated by Baliao acupoints moxibustion and acupuncture combined with oral administration of Yiqi Runchang... by LI Juan (李娟), FENG Ruiping (冯瑞萍), LI Ling (黎玲)

“…The patient received oral administration of Yiqi Runchang decoction to regulate the body constitution. In addition, a prescription of drinking habits was administrated to promote defecation, and other interventions such as dietary guidance, exercise and emotion care were carried out to relieve the symptoms of Qi-deficiency syndromes. …”
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A dual-phase biologic augmentation of rotator cuff healing in a preclinical rat model using interleukin-17F and low-dose lithium by Manisha R. Mistry, MD, MSc, Yufa Wang, MD, MSc, Cari M. Whyne, PhD, David M. Phillips, MSc, Wendy Oakden, PhD, Paul Marks, MD, Jimmy Tat, MD, MSc, Diane Nam, MD, MSc

“…Control rats received no additional intervention before surgical closure. Evaluation of healing was then preformed using MRI imaging, biomechanical testing, and histological analysis at the bone–tendon interface. …”
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Differential Signature of the Centrosomal MARK4 Isoforms in Glioma by Ivana Magnani, Chiara Novielli, Laura Fontana, Silvia Tabano, Davide Rovina, Ramona F. Moroni, Dario Bauer, Stefania Mazzoleni, Elisa A. Colombo, Gabriella Tedeschi, Laura Monti, Giovanni Porta, Silvano Bosari, Carolina Frassoni, Rossella Galli, Lorenzo Bello, Lidia Larizza

“…Moreover, while both MARK4 isoforms are localised to the centrosome and midbody in glioma and normal cells, the L isoform exhibits an additional nucleolar localisation in tumour cells. Conclusions: The observed switch towards MARK4L suggests that the balance between the MARK4 isoforms is carefully guarded during neural differentiation but may be subverted in gliomagenesis. …”
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Autophagy inhibitor 3-methyladenine mitigates the severity of colitis in aged mice by inhibiting autophagy by Ailing Liu, Hongying Wang, Hong Lv, Hong Yang, Yue Li, Jiaming Qian

“…Treatment with 3-methyladenine suppressed autophagy in intestinal epithelial cells (IECs) and alleviated colitis severity. Additionally, 3-methyladenine reduced macrophage recruitment, decreased IL-6 levels, and inhibited NF-κB signaling, thereby mitigating inflammation. …”
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Quantitative Characterization for the Micronanopore Structures of Terrestrial Shales with Different Lithofacies Types: A Case Study of the Jurassic Lianggaoshan Formation in the So... by Weiwei Liu, Kun Zhang, Qianwen Li, Zhanhai Yu, Sihong Cheng, Jiayi Liu, Pei Liu, Fengli Han, Liangyi Tang, Zhengwei Li, Xuejiao Yuan, Yiming Yang, Yao Zeng, Chen Zhang

“…Due to the specificity of the geological background, terrestrial strata are widely distributed in the major hydrocarbon-bearing basins in China. In addition, terrestrial shales are generally featured with high thickness, multiple layers, high TOC content, ideal organic matter types, and moderate thermal evolution, laying a solid material foundation for hydrocarbon generation. …”
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Pharmacometabolomics Enables Real-World Drug Metabolism Sciences by Fleur B. Nijdam, Marieke A. J. Hof, Hans Blokzijl, Stephan J. L. Bakker, Eelko Hak, Gérard Hopfgartner, Frank Klont, on behalf of the TransplantLines Investigators

“…<b>Results</b>: Our analyses confirmed the urinary presence of CsA and six known metabolites. Additionally, we detected three known metabolites not previously reported in urine and identified one unreported metabolite, potentially suggesting the involvement of glutathione conjugation. …”
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An improved ShuffleNetV2 method based on ensemble self-distillation for tomato leaf diseases recognition by Shuiping Ni, Yue Jia, Mingfu Zhu, Mingfu Zhu, Yizhe Zhang, Wendi Wang, Shangxin Liu, Yawei Chen

“…Among lightweight models, it has the smallest parameter count and the highest recognition accuracy.DiscussionThe results demonstrate that the optimized ShuffleNetV2 is more suitable for deployment on edge devices for real-time tomato disease detection. Additionally, multiple shallow models achieve varying degrees of compression for ShuffleNetV2, providing flexibility for model deployment.…”
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Interventional factors influencing natural killer cell immunity in colorectal cancer: a systematic review by Wai Sinn Soh, Grace L. Burns, Tharindu Senanayake, Raquel Cameron, Kerith Duncanson, Guy D. Eslick, Sharmila S. Prasad, Stephen R. Smith, Simon Keely

“…This effect was observed across all examined medications, including fentanyl, morphine, propofol and oxycodone. Additionally, blood transfusion also resulted in decreased NK cell cytotoxicity and activity in CRC patients. …”
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Outpatient Versus Inpatient Total Joint Arthroplasty: Do Medically and Socially Complex Patients Require More Resources but Achieve Similar Outcomes? by Justin Leal, BS, Christine J. Wu, MD, Niall H. Cochrane, MD, Thorsten M. Seyler, MD, PhD, William A. Jiranek, MD, Samuel S. Wellman, MD, Michael P. Bolognesi, MD, Sean P. Ryan, MD

“…Conclusions: Medically and socially complex patients undergoing TJA required additional resources during the 90-day postoperative window; however, they achieved similar survivorship as patients who met criteria for outpatient surgery.…”
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SGCL-LncLoc: An Interpretable Deep Learning Model for Improving lncRNA Subcellular Localization Prediction with Supervised Graph Contrastive Learning by Min Li, Baoying Zhao, Yiming Li, Pingjian Ding, Rui Yin, Shichao Kan, Min Zeng

“…Then, SGCL-LncLoc applies graph convolutional networks to learn the comprehensive graph representation. Additionally, we propose a computational method to map the attention weights of the graph nodes to the weights of nucleotides in the lncRNA sequence, allowing SGCL-LncLoc to serve as an interpretable deep learning model. …”
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To cool or not to cool: understanding and improving cooling centre use in metro vancouver through community-based participatory action research by Liv Yoon, Giulia Belotti, Rachel Stern, Katherine White, Aida Mohajeri, Abby Zhou, Eduardo Rosales Miranda, Erika Siao, Thanh Le, Jeff Masuda, Eun-young Lee, Chris Buse

“…SPs faced constraints with staffing, limited hours, and underutilization of additional services. Tensions emerged between individual, do-it-yourself (DIY) approaches and collective solutions, with participants seeking agency in their choices while acknowledging the need for improved, community-based interventions. …”
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Diversity of new Russian bread wheat cultivars according to leaf rust resistance genes by E. I. Gultyaeva, E. L. Shaydayuk, V. V. Veselova, R. E. Smirnova, E. V. Zuev, A. G. Khakimova, O. P. Mitrofanova

“…These cultivars seem to contain additional resistance genes. A high level of resistance to leaf rust in ‘Omskaya 44’ is provided by a combination of the Lr19, Lr26, Lr1 and Lr3 genes. …”
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