Investigating the Effect and Potential Mechanism of Rhamnetin 3-<i>O</i>-α-Rhamnoside on Acute Liver Injury In Vivo and In Vitro by Dandan Deng, Borong Zhao, Hong Yang, Songsong Wang, Ziying Geng, Jiangtao Zhou, Guane Yang, Liwen Han

“…The hepatoprotective activity of ARR was evaluated by assessing liver morphology, liver function indices, oxidative stress, and the mRNA expression levels of inflammation-related genes in the zebrafish model. Additionally, the ROS level, inflammatory factors, and protein expression related to the IKKβ/NF-κB signaling pathway were measured to investigate a potential mechanism of ARR in HepG2 cells. …”
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The 2023 dengue outbreak in Lombardy, Italy: A one-health perspective by Francesca Rovida, Marino Faccini, Carla Molina Granè, Irene Cassaniti, Sabrina Senatore, Eva Rossetti, Giuditta Scardina, Manuela Piazza, Giulia Campanini, Daniele Lilleri, Stefania Paolucci, Guglielmo Ferrari, Antonio Piralla, Francesco Defilippo, Davide Lelli, Ana Moreno, Luigi Vezzosi, Federica Attanasi, Marzia Soresini, Manuela Barozzi, Lorenzo Cerutti, Stefano Paglia, Angelo Regazzetti, Maurilia Marcacci, Guido Di Donato, Marco Farioli, Mattia Manica, Piero Poletti, Antonio Lavazza, Maira Bonini, Stefano Merler, Fausto Baldanti, Danilo Cereda, Antonella Sarasini, Milena Furione, Dalila Mele, Federica Bergami, Josè Camilla Sammartino, Alessandro Ferrari, Greta Romano, Antonino Maria Guglielmo Pitrolo, Maya Carrera, Rita Brugnoli, Nunzia Laini, Francesca Bonalda, Sara Arfani, Giuditta Zamboni, Fanny Delfanti, Piergiuseppe Ferrari, Anxhela Dafa, Antonella Negri, Filippa Parisi, Marcello Tirani, Michela Viscardi, Gabriele Del Castillo, Federica Morani, Francesco Scovenna, Sheila Sansebastian, Manuel Maffeo, Mario Chiari, Enrico Tallarita

“…Results: Overall, 416 subjects participated to the screening program and 20 were identified as DENV-1 cases (15 confirmed and 5 probable). In addition, DENV-1 infection was diagnosed in 24 symptomatic subjects referred to the local Emergency Room Department for suggestive symptoms and 1 case was identified through blood donation screening. …”
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Phytochemical screening and neuro-pharmacological activity of Mimosa pudica flowers: Integrating in vitro, in silico and in vivo approaches by Fahmida Alam, Rashedul Alam, A.T.M. Yusuf, Joya Datta Ripa, Raktim Das Nithin, Sourav Barua, Mohammed Fazlul Kabir, Seong-Tshool Hong, Hea-Jong Chung

“…The extract, given at doses of 200 mg/kg and 400 mg/kg body weight, showed notable effects on neurobehavioral parameters, similar to the conventional medications Diazepam and Escitalopram (1 mg/kg body weight). …”
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Assessing recovery time of ecosystems in China: insights into flash drought impacts on gross primary productivity by M. Lu, M. Lu, H. Sun, H. Sun, H. Sun, Y. Yang, J. Xue, H. Ling, H. Zhang, W. Zhang

“…In this study, we investigate the recovery time patterns in a terrestrial ecosystem in China based on GPP using a random forest regression model and the SHapley Additive exPlanations (SHAP) method. A random forest regression model was developed to analyse the factors influencing recovery time and establish response functions through partial correlation for typical flash drought recovery periods. …”
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Towards equitable carbon responsibility: Integrating trade-related emissions and carbon sinks in urban decarbonization by Junliang Wu, Yafei Wang, Shuya Zhang, Yu Zhu, Bingyue Fu, Zhihui Zhang, Hanxi Chen, Shaoqing Chen

“…The redistribution of outsourced emissions through supply chains alleviates the mitigation burden on producer cities by 20–30 %. Additionally, accounting for carbon sinks substantially influences CMR allocation, particularly in forest-rich cities, which may see their carbon budgets increase by up to 10 %. …”
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Short path molecular distillation of the essential oil from Pinus roxburghii oleoresin affords volatile fractions with powerful antioxidant and antimicrobial activities comparable... by Muhammad Adnan Ayub, Hawraz Ibrahim M. Amin, Rameen Waseem, Kamaran Younis M. Amin, Muhammad Asif Hanif, Amjad Hussain, Kovan Dilawar Issa, Jorge Ramírez, Chabaco Armijos, Muhammad Zubair, Giovanni Vidari

“…The oil was subsequently separated by short path molecular distillation into fractions and sub-fractions whose antioxidant activity was determined by the DPPH scavenging assay, the inhibition of linoleic acid peroxidation test, the FRAP assay, and the H2O2 scavenging assays. In addition, the antimicrobial activity of the fractions and sub-fractions against the bacteria Pasteurella multocida, Staphylococcus aureus, Escherichia coli, and Bacillus subtilis, and the fungal strains Fusarium solani, Alternaria alternata, Aspergillus flavus, and Aspergillus niger, was measured by the agar well diffusion method, the microdilution broth assay and the resazurin microtiter plate test. …”
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Factors affecting patient satisfaction during endoscopic procedures by Maryam Ghazala, E-Hinna Rashk, Sardar Saman, Khan Jahangir, Isram Javaria, Hassan Fayyaz

“…The study found that the most significant factors affecting patient satisfaction were waiting time to get an appointment (15.5 %), waiting time on the day of the procedure (17.0 %) and pain or discomfort during and after the procedure (15.6 %). Additionally, the personal manner of the physician and nurses, as well as comprehensive explanations before and after the procedure, were also significant factors. …”
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Post-treatment of rat aflatoxicosis by camel milk and silymarin by Nahla H. Hassaneen, Shabaan A. Hemeda, Abeer F. El Nahas, Ghadeer M. Albadrani, Muath Q. Al-Ghadi, Zuhair M. Mohammedsaleh, Sabreen E. Fadl, Eman M. El-Diasty, Hader I. Sakr, Hader I. Sakr

“…Camel milk group (supplied with 1.4 mg aflatoxin/kg diet) for 28 days and camel milk (1 milliliter of camel milk per kilogram of body weight) orally, from day 29 to day 43). Silymarin (supplied with 1.4 mg aflatoxin/kg diet) for 28 days and silymarin (20 mg silymarin/kg b.wt), orally, from day 29 to day 43). …”
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The study protocol of a double-blind randomized controlled trial of EMDR and multifocal transcranial current stimulation (MtCS) as augmentation strategy in patients with fibromyalg... by I. Gardoki-Souto, O. Martín de la Torre, B. Hogg, D Redolar-Ripoll, L. Martínez Sadurní, M. Fontana-McNally, J. M. Blanch, W. Lupo, V. Pérez, J. Radua, B. L. Amann, A. Valiente-Gómez, A. Moreno-Alcázar

“…This double-blind randomized controlled trial (RCT) analyzes if EMDR therapy is effective in the reduction of pain symptoms in FM patients, and if its potential is boosted with the addition of MtCS. Methods Ninety-six patients with FM and a history of traumatic events will be randomly allocated to the treatment as usual (TAU) condition, EMDR + active-MtCS condition, or EMDR + sham-MtCS condition. …”
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Quantitative Proteomics Analysis Reveals XDH Related with Ovarian Oxidative Stress Involved in Broodiness of Geese by Ning Zhou, Yaoyao Zhang, Youluan Jiang, Wang Gu, Shuai Zhao, Wanwipa Vongsangnak, Yang Zhang, Qi Xu, Yu Zhang

“…Antioxidant activity (GSH, CAT, SOD, T-AOC, and the content of H₂O₂) and the mRNA expression levels of antioxidant genes (GPX, SOD-1, SOD-2, CAT, COX-2, and Hsp70) were significantly higher in pre-broody geese compared to laying geese, while the expression of apoptosis-related genes (p53, Caspase-3, and Caspase-9) increased and the anti-apoptotic gene Bcl-2 decreased. Additionally, proteomic analysis identified 703 differentially expressed proteins (DEPs), primarily concentrated in the GO categories of the biological process (biological regulation, response to stimulus, etc.) and enriched in the KEGG pathways (PI3K-Akt signaling pathway, etc.). …”
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Acupoint catgut embedding alleviates experimental autoimmune encephalomyelitis by modulating neuroinflammation and potentially inhibiting glia activation through JNK and ERK pathwa... by Xiaofang Liu, Liansheng Yang, Zhumin Su, Xueying Ma, Yingying Liu, Lili Ma, Xiaomeng Ma, Mingxia Ma, Xiaoyun Liu, Kun Zhang, Kun Zhang, Xiaohong Chen

“…The effects of ACE treatment were evaluated by monitoring body weight and EAE severity scores. Behavioral tests, histopathological analysis, ELISA, and flow cytometry were conducted to assess the therapeutic efficacy of ACE. …”
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Altered NKp30, NKp46, NKG2D, and DNAM-1 Expression on Circulating NK Cells Is Associated with Tumor Progression in Human Gastric Cancer by Bin Han, Fang-yuan Mao, Yong-liang Zhao, Yi-pin Lv, Yong-sheng Teng, Mubing Duan, Weisan Chen, Ping Cheng, Ting-ting Wang, Zhong-yuan Liang, Jin-yu Zhang, Yu-gang Liu, Gang Guo, Quan-ming Zou, Yuan Zhuang, Liu-sheng Peng

“…Furthermore, TGF-β1 significantly downregulated the expression of NKp30, NKp46, NKG2D, and DNAM-1 on NK cells in vitro, and the addition of galunisertib, an inhibitor of the TGF-β receptor subunit I, reversed this downregulation. …”
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Legionella pneumophila subverts the antioxidant defenses of its amoeba host Acanthamoeba castellanii by Alban Hay, Willy Aucher, Romain Pigeault, Joanne Bertaux, Alexandre Crépin, Quentin Blancart Remaury, Yann Héchard, Ascel Samba-Louaka, Romain Villéger

“…It is known that L. pneumophila WT can block the activation of NADPH oxidase as soon as it enters the macrophage and suppress ROS production compared to ΔdotA mutant strain. In addition, it has been shown in macrophages that L. pneumophila WT decreases ROS at 24 h p.i.; here we confirm this result in amoebae and suggest that this decrease could be partly explained by L. pneumophila differentially regulated host antioxidant defense transcripts at 6 h p.i.. …”
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Review and Prospects of Key Technologies for Integrated Systems in Hydrogen Production from Offshore Superconducting Wind Power by Liufei Shen, Cheng Zhang, Feiyue Shan, Long Chen, Shuai Liu, Zhiqiang Zheng, Litong Zhu, Jinduo Wang, Xingzheng Wu, Yujia Zhai

“…This paper provides a comprehensive overview of the fundamental structure and characteristics of this integrated technology and further identifies the key challenges in its application, including the dynamic adaptability of electrolytic water hydrogen production technology, as well as the need for large-capacity, long-duration storage solutions. Additionally, this paper explores the future technological direction of this integrated system, highlighting the need to overcome the limitations of electrical energy adaptation within the system, improve product purity, and achieve large-scale applications.…”
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Visible light photocatalytic degradation of tetracycline using copper ferrite nanoparticles synthesized via Glycine-Assisted combustion method by A. Dinesh, K. Radhakrishnan, V. Renuga, Rajendra P. Patil, Suriyaprakash Rajadesingu, S. Suthakaran, L. Guganathan, Manikandan Ayyar, Madhappan Santhamoorthy, Lalitha Gnanasekaran, Munawar Iqbal

“…The degradation efficiency reached a maximum value of 95.8 % for a 150 min irradiation under the optimum condition of the photocatalytic activity was further raised by 25 % by the addition of hydrogen peroxide (H2O2). The CuFe2O4 NPs had rather high recyclability after the photocatalytic process, they had 90 % of their initial activity, which was tested after the fifth run. …”
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Effect of Prolonged-Release Pirfenidone on Renal Function in Septic Acute Kidney Injury Patients: A Double-Blind Placebo-Controlled Clinical Trial by Jonathan S. Chávez-Iñiguez, Jorge L. Poo, Miguel Ibarra-Estrada, Leonel García-Benavides, Guillermo Navarro-Blackaller, Cynthia Cervantes-Sánchez, Eduardo Nungaray-Pacheco, Ramón Medina-González, Juan Armendariz-Borunda, Guillermo García-García

“…Mild adverse events were not different among the groups. Conclusion. PR-PFD did not improve the clinical course of sAKI and seemed to be safe in terms of adverse events. …”
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Phlorofucofuroeckol-A: A Natural Compound with Potential to Attenuate Inflammatory Diseases Caused by Airborne Fine Dust by Eun-Gyeong Lee, Sung-Kun Yim, Sang-Min Kang, Byung Jae Ahn, Chang-Kwon Kim, Mina Lee, Dongseob Tark, Gun-Hee Lee

“…Further investigation of inflammatory-associated signaling demonstrated that PFF-A inhibited IL-1β expression by modulating the NF-κB/MAPK signal pathway in FD-induced RAW 264.7 cells. Additionally, gene profiling revealed the early activation of various signature genes involved in the production of inflammatory cytokines and chemokines using gene profiling. …”
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Development of a droplet digital PCR method for the detection of Ureaplasma urealyticum by Yong-Zhuo Zhou, Yun-Hu Zhao, Yan-Lan Chen, Hua Luo, Yu-lin Zhou, Bing Gu, Wei-Zhen Fang, Chao-Hui Duan, Xu-Guang Guo

“…With a high specificity, no positive microdrop were detected in eight negative control pathogens in this experiment. In addition, ddPCR detection of UU has good repeatability, and the calculated CV is 2.1 %. …”
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Comparing Campylobacter jejuni to three other enteric pathogens in OligoMM12 mice reveals pathogen-specific host and microbiota responses by Mathias K.-M. Herzog, Audrey Peters, Nizar Shayya, Monica Cazzaniga, Kardokh Kaka Bra, Trisha Arora, Manja Barthel, Ersin Gül, Luca Maurer, Patrick Kiefer, Philipp Christen, Katharina Endhardt, Julia A. Vorholt, Gad Frankel, Markus M. Heimesaat, Stefan Bereswill, Cormac G. M. Gahan, Marcus J. Claesson, Xavier Domingo-Almenara, Wolf-Dietrich Hardt

“…Notably, we reveal for the first time that C. jejuni stably colonizes OligoMM12 mice, triggering inflammation. Additionally, our comparative approach successfully identifies pathogen-specific responses, including the detection of genes uniquely associated with C. jejuni infection in humans. …”
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Lâdînî Latin Alfabesi Milliyetçilik Çağında Reşid Rıza’nın Arapça ve Türkçe Üzerine Düşünceleri by Rainer Brunner, Hilal Livaoğlu Mengüç

“…Bu şiirlerle, ondan bir kuşak daha yaşlı bir alimden, Ahmed Abdulcevad el-Kayâtî’den övgüler aldı ve böylece çağdaşlarının yapmayı çoktan bıraktığı bir şeyi yapmaya başladı. …”
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