Impact of eggshell membrane on metabolism and cell adhesion in oxidatively stressed canine chondrocytes by Juraj Vozar, Nikola Hudakova, Natalia Nosalova, Mykhailo Huniadi, Dana Marcincakova, Slavomir Hornak, Lubica Hornakova, Petra Majerova, Dasa Cizkova, Dasa Cizkova

“…The isolated neonatal chondrocytes demonstrated a high proliferation rate and increased glycosaminoglycan (GAG) production during cultivation. In addition, the expression of key cartilage markers, including collagen types II and IX, and aggrecan, confirmed the retention of the chondrocyte phenotype. …”
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Rational design of nitrogen and fluorine co-doped metal-free porous carbons electrocatalysts for highly efficient oxygen reduction and zinc-air batteries by Linqiang Li, Na Qin, Huayun Ma, Jing Liu, Zhiqiang Zhu, Yaxiong Huo, Lipeng Zhai, Liwei Mi

“…TF-1000 had a high initial potential (0.90 V) and half-wave potential (0.83 V) in an alkaline medium, indicating good catalytic activity. In addition, the ORR stability of TF-1000 was better than that of commercial Pt/C (20%). …”
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Consistency Regularization for Semi-Supervised Semantic Segmentation of Flood Regions From SAR Images by G. Savitha, S. Girisha, Pundarika Sughosh, Dasharathraj K. Shetty, Jayaraj Mymbilly Balakrishnan, Rahul Paul, Nithesh Naik

“…Accurately defining the extent of floods is a problem for traditional flood mapping approaches, which emphasizes the vital need for modern technologies such as Synthetic Aperture Radar (SAR) imaging. Additionally, there is a need to develop computer-aided tools specifically designed for automatically identifying areas that are vulnerable to flooding using SAR data. …”
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Self-Emulsifying Drug Delivery Systems (SEDDS): Transition from Liquid to Solid—A Comprehensive Review of Formulation, Characterization, Applications, and Future Trends by Prateek Uttreja, Indrajeet Karnik, Ahmed Adel Ali Youssef, Nagarjuna Narala, Rasha M. Elkanayati, Srikanth Baisa, Nouf D. Alshammari, Srikanth Banda, Sateesh Kumar Vemula, Michael A. Repka

“…The review systematically analyzes existing studies on SEDDS, focusing on their classification into liquid and solid forms and their preparation methods, including spray drying, hot-melt extrusion, and adsorption onto carriers. …”
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Effect of Praziquantel on Preventing Delayed Infection of <i>Schistosoma japonicum</i> in Buffaloes and Goats by Xiang Gui, Bing Shao, Haoran Zhong, Rongxue Lv, Hao Li, Ke Lu, Yang Hong, Zhiqiang Fu, Zhenjie Lu, Mengge Xu, Yamei Jin, Jinming Liu

“…In the present study, buffaloes and goats were pretreated with PZQ at various doses (7–25 mg/kg body weight), followed by infection with <i>S. japonicum</i> cercariae. …”
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Rap1 and mTOR signaling pathways drive opposing immunotoxic effects of structurally similar aryl-OPFRs, TPHP and TOCP by Bilin Zhao, Shuang Zheng, Gaoxiang Yang, Zhijun He, Jiewei Deng, Lijuan Luo, Xinyan Li, Tiangang Luan

“…Aryl organophosphorus flame retardants (aryl-OPFRs), commonly used product additives with close ties to daily life, have been regrettably characterized by multiple well-defined toxicity risks. …”
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Laser-induced breakdown spectroscopy applied to cattle compost for phosphorus quantification by Alberto Lencina, Gustavo Romagnoli, Andrea Alonso, Noelia Ramos, Cristian D’Angelo, Lina Lett, Silvia Mestelan

“…Samples were dried at 50°C for dry matter characterization. As a reference method to determine total P concentration, wet digestion and colorimetry were employed. …”
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Development and characterization of a chicory extract fermented by Akkermansia muciniphila: An in vitro study on its potential to modulate obesity-related inflammation by A. Chervet, R. Nehme, C. Defois-Fraysse, C. Decombat, C. Blavignac, C. Auxenfans, B. Evrard, S. Michel, E. Filaire, J.-Y. Berthon, A. Dreux-Zigha, L. Delort, F. Caldefie-Chézet

“…It also decreased leptin expression while increasing adiponectin and HSL expression levels in both adipocytes and co-cultures. In addition, C-Akm extract stimulated adiponectin secretion in the co-culture model. …”
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Comparative anti-methanogenic ability of green algae (C. reinhardtii) with/without nanoparticles: in vitro gas and methane production by Valiollah Palangi, Adem Kaya, Muhlis Macit, Hayrunnisa Nadaroglu, Hayrullah Bora Ünlü, Ali Kaya, Ashkan Fekri, Ayaz Mammadov, Maximilian Lackner

“…To precisely ascertain the impact particular Rhodophyta on greenhouse gas emissions, additional investigation is needed.…”
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Study on SHP2 Conformational Transition and Structural Characterization of Its High-Potency Allosteric Inhibitors by Molecular Dynamics Simulations Combined with Machine Learning by Baerlike Wujieti, Mingtian Hao, Erxia Liu, Luqi Zhou, Huanchao Wang, Yu Zhang, Wei Cui, Bozhen Chen

“…Furthermore, to biophysically interpret high-dimensional simulation trajectories, we employed interpretable machine learning methods, specifically extreme gradient boosting (XGBoost) with Shapley additive explanations (SHAP), to comprehensively analyze the simulation data. …”
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Clonal hematopoiesis in patients with autoimmune thrombocytopenia: an international multicenter study by Bruno Fattizzo, Alfredo Marchetti, Alessandro Bosi, Carmelo Gurnari, Juri Alessandro Giannotta, Giacinto Luca Pedone, Elena Rossi, Valentina Carrai, Andrea Guido, Filippo Brioschi, Monica Carpenedo, Monica Crugnola, Domenica Caramazza, Livia Leuzzi, Monia Marchetti, Gabriele Merati, Simona Malato, Fabrizio Vianello, Andrea Patriarca, Hussein Awada, Marta Bortolotti, Marta Canzi, Niccolò Bolli, Marco Capecchi, Frederick Chen, Andrea Artoni, Jaroslaw P. Maciejewski, Wilma Barcellini

“…Mutated patients were more frequently older males and showed a shorter time from first to second-line therapy, particularly with thrombopoietin receptor agonist (TPO-RA). Additionally, clonal hematopoiesis was associated with increased thrombotic risk (26% vs 8% in NGS-negative cases; P = .01), independently from TPO-RA exposure, though with an age effect. …”
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Electronic and photophysical properties of copper (II) Complexes: Insights into solvatochromic Effects, Photoreduction, and fluorescence behavior by Haja Tar, Lama M. Alhomaidan, Lotfi Beji, Abrar S. Alnafisah, Noura Kouki, Sabri Messaoudi, Fahad M. Alminderej, Azizah A. Algreiby, Lotfi M. Aroua

“…Photolysis experiments underpin the complexes’ behavior under light irradiation, revealing reversible photoreduction processes and the formation of novel photoproducts. Notably, the addition of triethylamine influences photolysis kinetics, elucidating complex interactions. …”
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Working experiences of remote interpreters in health care settings—insights from Austria and Germany by Sophie Klomfar, Sophie Klomfar, Anna Teufel, Gernot Gerger, Maria Kletečka-Pulker, Maria Kletečka-Pulker, Klara Doppler, Klara Doppler, Magdalena Eitenberger, Magdalena Eitenberger, Sabine Völkl-Kernstock, Sabine Völkl-Kernstock

“…We tested this hypothesis using a quantitative approach. Additionally, we analyzed qualitative data to uncover more enabling and hindering factors.MethodsA sample of 87 interpreters working in Austria and Germany was included in this multi-methods study. …”
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Improving dexamethasone drug loading and efficacy in treating rheumatoid arthritis via liposome: Focusing on inflammation and molecular mechanisms by Mohammad Yasin Zamanian, Hamidreza Zafari, Maria K. Osminina, Alla A. Skakodub, Raed Fanoukh Aboqader Al‐Aouadi, Maryam Golmohammadi, Nikta Nikbakht, Iman Fatemi

“…The liposomal formulation also shows better hemocompatibility, fewer adverse effects on body weight and immune organ index, and a longer circulation time with higher bioavailability. …”
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Culture-independent detection of Mycobacterium tuberculosis complex DNA using targeted next generation sequencing in African buffalo (Syncerus caffer) oronasal swabs in South Afric... by Sinegugu Kholeka Mhlophe, Charlene Clarke, Giovanni Ghielmetti, Giovanni Ghielmetti, Megan Matthews, Tanya Jane Kerr, Michele Ann Miller, Wynand Johan Goosen, Wynand Johan Goosen

“…African buffaloes (Syncerus caffer) are wildlife maintenance hosts of Mycobacterium bovis (M. bovis), the causative agent of animal tuberculosis (aTB) in multiple ecosystems across South Africa. In addition to their role as keystone species, these animals are vital to South Africa’s economy as a highly valuable species. …”
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A framework to comprehensively assess lake health from a perspective of ecosystem integrity and services by Zhixuan Zhao, Fangfei Wei, Haotian Wu, Miao Yang, Xin Jin, Pengzhe Wang, Qing Wang

“…Furthermore, the reference state was carefully selected and used to set the health level and health scores. In addition, a fuzzy binary comparison method was used to assign the optimum weights for each index. …”
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Effects of Active Video Games Combined with Conventional Physical Therapy on Perceived Functionality in Older Adults with Knee or Hip Osteoarthritis: A Randomized Controlled Trial by Francisco Guede-Rojas, Cristhian Mendoza, Jorge Fuentes-Contreras, Cristian Alvarez, Bárbara Agurto Tarbes, Javiera Karina Muñoz-Gutiérrez, Adolfo Soto-Martínez, Claudio Carvajal-Parodi

“…The EG demonstrated greater improvements in WOMAC pain and the GroC scale (<i>p</i> < 0.05), maintaining most of the gains at follow-up, whereas the CG showed regression. Additionally, the EG had a higher proportion of responders, particularly for pain, while the CG had a predominance of non-responders and adverse responders. …”
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MELK prevents radiofrequency ablation-induced immunogenic cell death and antitumor immune response by stabilizing FABP5 in hepatocellular malignancies by Bu-Fu Tang, Wang-Ting Xu, Shi-Ji Fang, Jin-Yu Zhu, Rong-Fang Qiu, Lin Shen, Yang Yang, Qiao-You Weng, Ya-Jie Wang, Jia-Yi Ding, Xiao-Jie Zhang, Wei-Qian Chen, Li-Yun Zheng, Jing-Jing Song, Biao Chen, Zhong-Wei Zhao, Min-Jiang Chen, Jian-Song Ji

“…Mechanically, MELK binds to fatty acid-binding protein 5 (FABP5), and affects its ubiquitination through the K48R pathway to increase its stability, thereby activating protein kinase B (Akt)/mammalian target of rapamycin (mTOR) signaling axis to weaken the RFA-mediated antitumor effect. In addition, the synthesis of arginylglycylaspartic acid (RGD)-lipid nanoparticles (LNPs) targeting tumor cell-intrinsic MELK enhanced RFA efficacy in HCC. …”
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Identification of two new genetic loci for high-resolution genotyping of Enterocytozoon bieneusi by Meng Xinan, Ou Yonglin, Jiang Wen, Guo Yaqiong, Xiao Lihua, Feng Yaoyu, Li Na

“…In addition to the ribosomal internal transcribed spacer (ITS) locus, four loci (MS1, MS3, MS4, and MS7) have been identified to develop multilocus sequence typing tools for high-resolution genotyping of Enterocytozoon bieneusi in previous studies. …”
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Adipocyte heterogeneity and tumor infiltration of adipose tissue in patients with metastatic breast cancer by Hava Izci, Gitte Zels, Anirudh Pabba, Marion Maetens, François Richard, Maxim De Schepper, Josephine Van Cauwenberge, Ha-Linh Nguyen, Kristien Borremans, Sophia Leduc, Karen Van Baelen, Sigrid Hatse, Tatjana Geukens, Amena Mahdami, Hans Wildiers, Patrick Neven, Wouter Van Den Bogaert, Giuseppe Floris, Christine Desmedt

“…Results: Distant adipocyte size did not significantly differ across fat depots. …”
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