Spatial Analysis of Building Density and Liquefaction Spread in Izmit Bay and its Surroundings by Arzu Erener, Metin Aşcı, Gül Gülsoy, Aydın Üstün, Muhammed Ali Güvenaltın, Erman Şentürk, Sefa Yalvaç, Fatma Canaslan Çomut, T. Serkan Irmak, Haluk Konak, Pakize Küreç Nehbit, Efdal Kaya, Burak Kotan, Selin Öye

“…Among the spatial autocorrelation analysis, Local Moran’s I statistics were taken into consideration comparatively. In addition, the liquefaction potential observed around the bay and its surroundings is evaluated for 0-3 m, 3-6 m, 6-9 m, 9-12 m from 33-35 m depths. …”
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Effectiveness of nurse-led volunteer support and technology-driven pain assessment in improving the outcomes of hospitalised older adults: protocol for a cluster randomised control... by Max K Bulsara, Christopher Etherton-Beer, Rosemary Saunders, Kate Crookes, Mustafa Atee, Caroline Bulsara, Beverley Ewens, Olivia Gallagher, Renee M Graham, Karen Gullick, Sue Haydon, Kim-Huong Nguyen, Bev O'Connell, Karla Seaman, Jeff Hughes, Seng Giap Marcus Ang, Debra Scaini

“…Data will be collected on admission, at discharge and at 30 days post discharge, with additional data collected during hospitalisation comprising records of pain assessment and volunteer support activity. …”
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Peering into the Black Box: Forward Modeling of the Uncertainty Budget of High-resolution Spectroscopy of Exoplanet Atmospheres by Arjun B. Savel, Megan Bedell, Eliza M.-R. Kempton, Peter C. B. Smith, Jacob L. Bean, Lily L. Zhao, Kaze W. K. Wong, Jorge A. Sanchez, Michael R. Line

“…However, limiting-case, strongly varying tellurics can bias the retrieved velocities and gas abundances. Additionally, in the low signal-to-noise ratio limit, constraints on gas abundances become highly non-Gaussian. …”
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Helminth diversity of nutria (Myocastor coypus) across the Morava basin in the Czech Republic by Michal Benovics, Eva Nosková, Anna Klimešová, Lucie Škorpíková, Ema Jaššová, Jakub Drimaj, Jan Slováček, Ondřej Mikulka

“…A total of 46 nutria cadavers were collected at 8 locations in the Morava River basin and examined using standard parasitological post-mortem procedures. Additionally, coprological and molecular methods were used to identify the parasites. …”
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Effects of photobiomodulation therapy in patients with chronic non-specific low back pain: protocol for a randomised placebo-controlled trial by Lucíola da Cunha Menezes Costa, Shaiane Silva Tomazoni, Leonardo Oliveira Pena Costa, Layana de Souza Guimarães, Amanda Costa Araujo, Dafne Port Nascimento, Flávia Cordeiro de Medeiros, Marina Athayde Avanzi

“…The secondary outcomes will be pain intensity and disability measured at 3, 6 and 12 months after randomisation, in addition to specific disability and global perceived effect in all time points.Ethics and dissemination The study was approved by the Research Ethics Committee of Universidade Cidade de São Paulo. …”
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Ten-Year Persistence of Biologic Drugs in Psoriasis and Its Relationship with Pharmacogenetic Biomarkers by Andrea Rodríguez-Lopez, María Martínez-Sendino, Rocío Prieto-Pérez, Paula Soria-Chacartegui, Eva González-Iglesias, Mario Aparicio-Domínguez, Sonsoles Berenguer-Ruiz, Esteban Daudén, Francisco Abad-Santos

“…<b>Background</b>: Psoriasis is a skin disease characterized by the presence of erythematous, scaly plaques on the extensor surfaces of the body. Treatment varies according to the stage of the disease, with the most severe cases being treated with biologic treatments that differ in efficacy and persistence over time. …”
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Comprehensive three-dimensional microCT and signaling analysis reveal the teratogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on craniofacial bone development in mice by Xiao-ming Wang, Cai-ming Qin, Dou Li, Xin-ran Xu, Xiao-jing Pan, Hui Xue

“…The attenuation of AhR signaling significantly blocked the osteogenic toxicity, and partly restored the expressing level of estrogen receptor α (ERα). Additional treatment with ERα agonist (PPT) significantly relieved the activation of AhR and rescued the impairment of osteogenesis caused by TCDD. …”
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The Cytotoxicity Assessment of Grapefruit Peel Essential Oil and Its Effect on Frying Stability of Sunflower Oil by Ghania Kaanin-Boudraa, Fatiha Brahmi, Linda Grimaud, Mohamed Lamine Freidja, Ourdia-Nouara Kernou, Daniel Henrion, Samir Hadjal, Khodir Madani, Lila Boulekbache-Makhlouf

“…Conclusion: The incorporation of this EO into sunflower oil during a deep-frying process led to a significant increase in its oxidative stability; therefore, it can be used as a food additive.…”
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Structural and iron content changes in subcortical vascular mild cognitive impairment: a combined voxel-based morphometry and quantitative susceptibility mapping study by Yushuang Liu, Yingqi Lu, Liyu Hu, Jinping Xu, Xingchen Liu, Nan Yang, Shangjie Chen, Zhongling Zhang

“…And ROI-based QSM analyses showed increased susceptibilities in left caudate nucleus and cerebellum in the svMCI. In addition, the susceptibility in left middle cingulate cortex and paracingulate gyrus was positively correlated associated with MoCA scores (r = 0.538 p < 0.001), and the susceptibility in the right middle frontal gyrus was negatively correlated with MoCA scores (r = -0.418 p < 0.007). …”
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SF1-specific deletion of the energy sensor AMPKγ2 induces obesity by Óscar Freire-Agulleiro, Ánxela Estévez-Salguero, Vitor Ferreira, Cassie Lynn Holleman, Julia García-Currás, Ismael González-García, Rubén Nogueiras, Manuel Tena-Sempere, Cristina García-Cáceres, Carlos Diéguez, Miguel López

“…Results: Our findings reveal that, in contrast to the obesity-protective effect of the genetic deletion of AMPKα subunits, the loss of AMPKγ2 in SF1 neurons leads to a sex-independent and feeding-independent obesity-prone phenotype due to decreased thermogenesis in brown adipose tissue (BAT) and reduced browning of WAT, resulting in lower energy expenditure. Additionally, SF1-Cre AMPKγ2 mice exhibit hepatic lipid accumulation, but surprisingly maintain normal glucose homeostasis. …”
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Experimental investigation on the anti-detonation performance of composite structure containing foam geopolymer backfill material by Hang Zhou, Hujun Li, Zhen Wang, Dongming Yan, Wenxin Wang, Guokai Zhang, Zirui Cheng, Song Sun, Mingyang Wang

“…The results showed that the foam geopolymer absorbed and dissipated the impact energy through continuous compressive deformation under high strain rates and dynamic loading, reducing the strain in the liner structure by 52% and increasing the pressure attenuation rate by 28%. Additionally, the foam geopolymer backfill reduced structural vibration and liner deformation, with the FGCS structure showing 35% less displacement and 70% less acceleration compared to the CLS. …”
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Air Particle Abrasion in Dentistry: An Overview of Effects on Dentin Adhesion and Bond Strength by Andreea Kui, Smaranda Buduru, Anca Labuneț, Sorina Sava, Dalia Pop, Iris Bara, Marius Negucioiu

“…Longer exposure times provided no additional benefit. Self-etch systems showed reduced bond strength compared to etch-and-rinse systems. …”
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Research on ultrasonic testing method for tangential contact stress based on equivalent medium theory by Nana Niu, Yongsheng Zhao, Zhifeng Liu, Ying Li, Lele Liu

“…The equivalent stress value of each node is calculated based on the von Mises stress by measuring the stress in the X/Y direction. In addition, a shear stress distribution cloud map of the contact surface is drawn. …”
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Stress during Lactation Induces Insulin Resistance Associated with an Increase in Type 1 Cannabinoid Receptors in Liver and Adipose Tissue by Liza Fonseca, Valeska Castillo, Carolina Aguirre, Paulo Silva, Ana M. Ronco, Miguel Llanos

“…During the whole lactation, male mice pups were daily subcutaneously injected (days 1–21) with a saline solution to produce a soft nociceptive stress (NS). Mice body weight and food intake were periodically evaluated. …”
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Biodegradable Mg alloy modified with bioactive exosomes for cardiovascular stent application by Ya-chen Hou, Jing-an Li, Chang Cao, Chang Su, Zhen Qin, Ge Zhang, Jia-cheng Guo, Jun-nan Tang, Jin-ying Zhang, Shao-kang Guan

“…The cytocompatibility data indicated the novel MgF2-PDA/exosome coating selectively reduced the tumor necrosis factor (TNF-α) expression and ROS release from macrophage, and promoted the α-SMA expression of smooth muscle cells. In addition, the MgF2-PDA/exosome coating also improved the adhesion, proliferation, CD31 expression and nitric oxide (NO) release of vascular endothelial cells (ECs), all of which contribute to the surface endothelialization. …”
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Advances in Hemodynamic Analysis in Cardiovascular Diseases Investigation of Energetic Characteristics of Adult and Pediatric Sputnik Left Ventricular Assist Devices during Mock Ci... by Alexander A. Pugovkin, Aleksandr G. Markov, Sergey V. Selishchev, Leonie Korn, Marian Walter, Steffen Leonhardt, Leo A. Bockeria, Olga L. Bockeria, Dmitry V. Telyshev

“…The need to simulate the operating conditions of the human body is a key factor in every study and engineering process of a bioengineering device developed for implantation. …”
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Pharmacological properties of biomimetic synthesized silver nanoparticles from endophytic fungus Coniothyrium chaingmaiense: KUMBMDBT-25 by Manjunatha Dadayya, Megha Gowri Thippeswamy, Nagaraju Shivaiah, Thoyajakshi Ramasamudra Siddaraju, Prakash Jayaramaiah, Sowmya Hirakannavar Veeranna, Thippeswamy Basaiah, Shridhar N Mathad, Ravikumar Hemagiri Gowda, Sachin Naik, Abdulaziz Abdullah AI Kheraif, Sajith Vellappally

“…Con-AgNPs exhibited notable biological attributes, including a cytotoxic effect of up to 38.82% and 19.15% at 200 µg/mL in an MTT assay measuring cell viability. Additionally, the nanoparticles demonstrated significant anti-inflammatory effects in both in vitro and in vivo studies, validating the biological and pharmacological potential of Con-AgNPs.…”
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MAT2A inhibitor AG-270/S095033 in patients with advanced malignancies: a phase I trial by Mrinal Gounder, Melissa Johnson, Rebecca S. Heist, Geoffrey I. Shapiro, Sophie Postel-Vinay, Frederick H. Wilson, Elena Garralda, Gerburg Wulf, Caroline Almon, Salah Nabhan, Elia Aguado-Fraile, Peng He, Mathilde Romagnoli, Mohammad Hossain, Rohini Narayanaswamy, Amel Sadou-Dubourgnoux, Michael Cooper, Vasileios Askoxylakis, Howard A. Burris, Josep Tabernero

“…Two partial responses were observed; five additional patients achieved radiographically confirmed stable disease for ≥16 weeks. …”
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A New Metabolism-Related Index Correlates with the Degree of Liver Fibrosis in Hepatitis C Virus-Positive Patients by Hirayuki Enomoto, Nobuhiro Aizawa, Hideji Nakamura, Ryo Takata, Yoshiyuki Sakai, Yoshinori Iwata, Hironori Tanaka, Naoto Ikeda, Tomoko Aoki, Kunihiro Hasegawa, Kazunori Yoh, Kenji Hashimoto, Akio Ishii, Tomoyuki Takashima, Masaki Saito, Hiroyasu Imanishi, Hiroko Iijima, Shuhei Nishiguchi

“…The new index showed a higher correlation related to liver function than FIB-4 and the APRI did. In addition, the index showed a higher AUROC value than that of FIB-4 and the APRI for prediction of liver cirrhosis. …”
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Comprehensive Evaluation of Bankruptcy Prediction in Taiwanese Firms Using Multiple Machine Learning Models by Hung V. Pham, Tuan Chu, Tuan M. Le, Hieu M. Tran, Huong T.K. Tran, Khanh N. Yen, Son V. T. Dao

“…The core contribution of this research is the establishment of a hybrid model that effectively combines multiple machine learning (ML) algorithms with advanced data with the Synthetic minority oversampling technique Tomek (SMOTE Tomek) or SMOTE- Edited Nearest Neighbor (SMOTE-ENN) resampling data technique to improve bankruptcy prediction accuracy. Additionally, a wrapper-based feature selection (FS) utilizing Binary Particle Swarm Optimization (BPSO) was utilized to find an optimal feature subset and boost the model’s predictive performance. …”
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