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  1. 61381

    Bisphenol A induces apoptosis and disrupts testosterone synthesis in TM3 cells via reactive oxygen species-mediated mitochondrial pathway and autophagic flux inhibition by Wenzhe Yang, Feilong Pan, Tong Zhao, Fangfang Chen, Wenqi Shao, Jinhao Wang, Shirui Wang, Zichen Zhao, Kexiang Liu, Shuchen Zhao, Lijia Zhao

    Published 2025-01-01
    “…The release of cytochrome C from damaged mitochondria into the cytoplasm activated a Caspase cascade reaction. In addition, excessive ROS levels impaired autophagic degradation by inhibiting the fusion of autophagosomes with lysosomes. …”
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  2. 61382

    Altered cytoskeleton dynamics in patient-derived iPSC-based model of PCDH19 clustering epilepsy by Rossella Borghi, Stefania Petrini, Valentina Apollonio, Marina Trivisano, Nicola Specchio, Sandra Moreno, Enrico Bertini, Marco Tartaglia, Claudia Compagnucci

    Published 2025-01-01
    “…Finally, performing live-imaging experiments using fluorescence recovery after photobleaching and by monitoring GFP-tagged end binding protein 3 (EB3) “comets,” we observe an impairment of the plus-end polymerization speed in PCDH19-mutated cortical neurons, therefore confirming the impaired MT dynamics. In addition to altering the mitotic spindle formation, the present data unveil that PCDH19 dysfunction leads to altered cytoskeletal rearrangement, providing therapeutic targets and pharmacological options to treat this disorder.…”
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  3. 61383

    Performance improvements and increased ruminal microbial interactions in Angus heifers via supplementation with native rumen bacteria during high-grain challenge by Fan Yang, Madison T. Henniger, Andrew S. Izzo, Emily A. Melchior, Brooke A. Clemmons, Mary A. Oliver, James R. Gaffney, Cameron Martino, Taylor B. Ault-Seay, Miranda L. Striluk, Jordan J. Embree, Juan F. Cordero-Llarena, Pierre-Yves Mulon, David E. Anderson, Mallory M. Embree, Phillip R. Myer

    Published 2025-01-01
    “…The combined 35 days of microbial supplementation resulted in an improved average daily gain (ADG) of 29% (P = 0.037) and a tendency toward a 19% decrease in the feed efficiency metric, gain to feed ratio (G: F) (P = 0.055). Additionally, administration of NRM to animals on a high-grain diet, improved ruminal microbiome stability (P < 0.001), potentially encouraging the conversion of rumen lactate to propionate over time via the succinate pathway and alleviating metabolic stress.…”
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  4. 61384

    RailPC: A large‐scale railway point cloud semantic segmentation dataset by Tengping Jiang, Shiwei Li, Qinyu Zhang, Guangshuai Wang, Zequn Zhang, Fankun Zeng, Peng An, Xin Jin, Shan Liu, Yongjun Wang

    Published 2024-12-01
    “…Abstract Semantic segmentation in the context of 3D point clouds for the railway environment holds a significant economic value, but its development is severely hindered by the lack of suitable and specific datasets. Additionally, the models trained on existing urban road point cloud datasets demonstrate poor generalisation on railway data due to a large domain gap caused by non‐overlapping special/rare categories, for example, rail track, track bed etc. …”
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  5. 61385

    FGF23-related hypophosphatemia in a patient with small cell lung cancer: a case report and literature review by Hajime Kato, Soichiro Kimura, Maho Taguchi, Takashi Sunouchi, Yoshitomo Hoshino, Naoko Hidaka, Nadia Edvige Foligno, Minae Koga, Katsunori Manaka, Hiroyuki Tamiya, Masanori Kawakami, Hidenori Kage, Yoichi Yasunaga, Masaomi Nangaku, Noriko Makita, Nobuaki Ito

    Published 2023-10-01
    “…These data suggested the overproduction of FGF23 in addition to ACTH and ADH. Because the octreotide loading test did not present a suppressive effect on ACTH or FGF23 levels, the patient was treated with phosphate supplementation, active vitamin D and metyrapone, which partially improved the serum phosphate and cortisol levels. …”
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  6. 61386

    Advances in carbon dioxide capture and conversion technologies: Industrial integration for sustainable chemical production by Okezie Emmanuel, Rozina, Thaddeus C. Ezeji

    Published 2025-01-01
    “…Innovative strategies, including integrated carbon capture and conversion (ICCC) and integrated carbon capture and utilization (ICCU), present promising pathways to reduce costs by combining capture and utilization processes within a single facility. Additionally, catalytic processes and biological systems, such as microalgae and microbial strains (e.g., acetogens), are paving the way for sustainable CO2 conversion into high-value products. …”
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  7. 61387

    Blood-based biomarkers suggest prolonged axonal Injury following pediatric mild traumatic brain injury by Andrew R. Mayer, Tracey V. Wick, Jessica R. McQuaid, Masen L. Boucher, Andrew B. Dodd, Cidney R. Robertson-Benta, Harm J. van der Horn, Erik B. Erhardt, Robert E. Sapien, Rawan Tarawneh, Rebekah Mannix

    Published 2025-02-01
    “…UCH-L1, GFAP and pTau181 did not differ between groups, but demonstrated negative associations with days post-injury (small to medium effect sizes) suggestive of a more rapid release/clearance. …”
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  8. 61388

    SSL-MBC: Self-Supervised Learning With Multibranch Consistency for Few-Shot PolSAR Image Classification by Wenmei Li, Hao Xia, Bin Xi, Yu Wang, Jing Lu, Yuhong He

    Published 2025-01-01
    “…Specifically, the data augmentation technique used in the pretext task involves a combination of various spatial transformations and channel transformations achieved through scattering feature extraction. In addition, the distinct scattering features of PolSAR data are considered as its unique multimodal representations. …”
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  9. 61389

    Nitric oxide modulates contrast suppression in a subset of mouse retinal ganglion cells by Dominic Gonschorek, Matías A Goldin, Jonathan Oesterle, Tom Schwerd-Kleine, Ryan Arlinghaus, Zhijian Zhao, Timm Schubert, Olivier Marre, Thomas Euler

    Published 2025-01-01
    “…By employing a sequential-recording paradigm, we could disentangle those additional adaptational response changes from drug-induced modulations. …”
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  10. 61390

    Addressing vaccine hesitancy in the training of healthcare professionals: Insights from the VAX-TRUST project by Fábio Rafael Augusto, Cátia Sá Guerreiro, Rita Morais, Joana Mendonça, André Beja, Tiago Correia, Ana Patrícia Hilário

    Published 2025-06-01
    “…Methods: The findings are based on a comprehensive Delphi survey conducted with a panel of 112 experts. Additionally, the study involved practical interventions carried out across seven European countries, engaging a total of 694 participants. …”
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  11. 61391

    Hepatocyte-derived liver progenitor-like cells attenuate liver cirrhosis via induction of apoptosis in hepatic stellate cells by Xu Zhou, Wen-Ming Liu, Han-Yong Sun, Yuan Peng, Ren-Jie Huang, Cai-Yang Chen, Hong-Dan Zhang, Shen-Ao Zhou, Hong-Ping Wu, Dan Tang, Wei-Jian Huang, Han Wu, Qi-Gen Li, Bo Zhai, Qiang Xia, Wei-Feng Yu, He-Xin Yan

    Published 2025-02-01
    “…In vitro experiments used HSCs to explore the antifibrotic properties of HepLPC-secretomes and their underlying molecular mechanisms. Additionally, proteomic analysis was conducted to characterize the protein composition of HepLPC-secretomes. …”
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  12. 61392

    Antimicrobial Activity and Mode of Action of N-Heterocyclic Carbene Silver(I) Complexes by Giusy Castagliuolo, Michela Di Napoli, Tshering Zangmo, Joanna Szpunar, Luisa Ronga, Anna Zanfardino, Mario Varcamonti, Diego Tesauro

    Published 2024-12-01
    “…The inhibitory properties of the four complexes were evaluated for their antimicrobial potential against a set of Gram (+) and Gram (−) bacterial strains and the fungus <i>C. albicans</i>. In addition, further investigations were made using fluorescence and scanning electron microscopy (SEM) in order to gain more insights into the mechanism of action. …”
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  13. 61393

    Programmed cell death-related gene IL20RA facilitates tumor progression and remodels tumor microenvironment in thyroid cancer by Yuqi Wang, Yunlong Zhang, Min Liu, Yu Liu, Yu Zeng, Wei Zhang, Shuping Wu, Linfei Hu, Xianhui Ruan, Xiangqian Zheng, Ming Gao, Jingzhu Zhao

    Published 2025-01-01
    “…The function of IL20RA which could potentially provide a foundation for additional investigations into diagnostic markers and treatment targets for THCA.…”
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  14. 61394
  15. 61395

    Global and Local Infall in the ASHES Sample (GLASHES). I. Pilot Study in G337.541 by Kaho Morii, Patricio Sanhueza, Timea Csengeri, Fumitaka Nakamura, Sylvain Bontemps, Guido Garay, Qizhou Zhang

    Published 2025-01-01
    “…Using dense gas tracers such as N _2 H ^+ ( J  = 1–0) and HNC ( J  = 3–2), we find signs of infall from the position–velocity diagram and more directly from the blue asymmetry profile in addition to the clump-scale velocity gradient. We estimate infall velocities from intermediate and low-mass cores to be 0.28–1.45 km s ^−1 , and infall rates to be on the order of 10 ^−4 –10 ^−3 M _⊙ yr ^−1 , both are higher than those measured in low-mass star-forming regions by more than a factor of 5 and an order of magnitude, respectively. …”
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  16. 61396

    Developmental changes of skin quality from breast, back, and thigh of Pekin ducks from 1 to 6 weeks of age by Hao Li, Wenxuan Zheng, Shuo Xin, Ye Hui, Yijun Zhu, Xi Lin, Huaqi Zhang, Yongwen Zhu

    Published 2025-02-01
    “…The results showed that the body weight, absolute skin weight, areas, and density, epidermal and dermal thickness (breast and thigh), shearing force, piercing force (back and thigh), and collagen content in Pekin ducks increased linearly and quadratically with age, reaching a plateau at 5-6 weeks of age (P < 0.05). …”
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  17. 61397

    Overexpression of HIF-2α, TWIST, and CXCR4 Is Associated with Lymph Node Metastasis in Papillary Thyroid Carcinoma by Ni Wang, Hao-Jun Luo, Guo-Bing Yin, Chao-Ran Dong, Man Xu, George G. Chen, Zhi-Min Liu

    Published 2013-01-01
    “…Additionally, HIF-2α, TWIST, and CXCR4 mRNA expression were assessed in 30 PTCs, 10 nodular hyperplasia, and 10 normal thyroid tissue specimens using real-time RT-PCR. …”
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  18. 61398

    Assisted Parkinsonism Diagnosis Using Multimodal MRI—The Role of Clinical Insights by Tobias Meindl, Alexander Hapfelmeier, Tobias Mantel, Angela Jochim, Jonas Deppe, Silke Zwirner, Jan S. Kirschke, Yong Li, Bernhard Haslinger

    Published 2025-01-01
    “…Objective To assess whether the performance of classifiers based on imaging derived biomarkers is improved with the addition of basic clinical information and to provide a practical solution to address the insecurity of classification results due to the uncertain clinical diagnosis they are based on. …”
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  19. 61399

    Electrochemically-driven solid oxide tubular membrane reactor for efficient separation of oxygen and argon by Yuanhui Tang, Yutao Hu, Sisi Wen, Song Lei, Yakai Lin, Li Ding, Haihui Wang

    Published 2025-06-01
    “…The resulting membrane reactor was compact, defect-free, and capable of producing Ar with a purity of 99.99 %. Additionally, under a constant total current of 0.75 A and an operating temperature of 800 °C, the membrane reactor demonstrated stable performance for over 130 hours, maintaining a Faradaic efficiency exceeding 95 %. …”
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  20. 61400

    A multi‐tagged SAR ocean image dataset identifying atmospheric boundary layer structure in winter tradewind conditions by Chen Wang, Justin E. Stopa, Doug Vandemark, Ralph Foster, Alex Ayet, Alexis Mouche, Bertrand Chapron, Peter Sadowski

    Published 2025-01-01
    “…This strategy extends the TenGeoP‐SARwv by identifying coexisting phenomena within a single SAR image and by the addition of mixed roll/cell states and cold pools. …”
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