TRAIL and Ceruloplasmin Inverse Correlation as a Representative Crosstalk between Inflammation and Oxidative Stress by Veronica Tisato, Stefania Gallo, Elisabetta Melloni, Claudio Celeghini, Angelina Passaro, Giorgio Zauli, Paola Secchiero, Carlo Bergamini, Alessandro Trentini, Gloria Bonaccorsi, Giuseppe Valacchi, Giovanni Zuliani, Carlo Cervellati

“…The observed association retained statistical significance after adjustment for additional confounding factors. After stratification for high-sensitivity C-reactive protein levels, the inverse association between TRAIL and ceruloplasmin levels remained strong and significant (r=−0.508, p<0.001, R2=0.260) only in the presence of inflammation, confirming the role of inflammation as emerged in in vitro experiments where recombinant TRAIL decreased ceruloplasmin expression levels in TNF-treated PBMC cultures. …”
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Assessment of Fish Species Biodiversity in the Yong River Basin Based on Environmental DNA Metabarcoding by Shengming Deng, Bai-an Lin, Yan Luo, Xiaolong Dang, Chengdan Ma, Yongcan Zhou, Xiang Zhang, Yang Zhang, Ning Xu, Shousong Jiang, Jiana Li, Jianlong Li

“…In this study, environmental DNA (eDNA) metabarcoding was employed to assess fish species biodiversity across five river sections of the Yong River basin in October 2022. Additionally, we checked the results against fishing gear (drift gillnets and ground cages) surveys and historical records. …”
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Impact of sleep deprivation on colon cancer: Unraveling the KynA-P4HA2-HIF-1α axis in tumor lipid metabolism and metastasis by Zuojie Peng, Jia Song, Wenzhong Zhu, Haijun Bao, Yuan Hu, Yongping Shi, Xukai Cheng, Mi Jiang, Feifei Fang, Jinhuang Chen, Xiaogang Shu

“…Objective: There is growing evidence that sleep deprivation promotes cancer progression. In addition, colon cancer patients often experience sleep deprivation due to factors such as cancer pain and side effects of treatment. …”
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Repetitive Transcranial Magnetic Stimulation: Is it an Effective Treatment for Cancer Pain? by Yanyuan Du, Yaoyuan Li, Jieqing Hu, Ruiying Fang, Yuming Liu, Liu Cai, Ying Song, Susu Ma, Jin Gao, Hanyue Zhang, Baihui Li, Hongtai Xiong, Huibo Yu, Shenglei Yang, Shuduo Zhu, Honggang Zheng

“…This review summarizes current research on rTMS for cancer pain, focusing on pain directly caused by tumors, pain from cancer treatments, postoperative pain, and cancer-related symptoms. Additionally, rTMS shows promise in improving cancer-related fatigue, anxiety, depression, and cognitive dysfunction, which can indirectly reduce cancer pain. …”
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The microbiome of Total Suspended Particles and its influence on the respiratory microbiome of healthy office workers by Giulia Solazzo, Sabrina Rovelli, Simona Iodice, Matthew Chung, Michael Frimpong, Valentina Bollati, Luca Ferrari, Elodie Ghedin

“…., as well as respiratory bacteria such as Staphylococcus aureus and Klebsiella pneumoniae. Additionally, both indoor and outdoor TSP samples contained broad spectrum antibiotic resistance genes. …”
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Isotopic Composition of Abiogenic Gas Produced in Closed-System Fischer-Tropsch Synthesis: Implications for the Origins of the Deep Songliao Basin Gases in China by Zhifu Wei, Yongli Wang, Gen Wang, Xueyun Ma, Wei He, Ting Zhang, Xiaoli Yu, Yan-Rong Zou

“…The deep Songliao Basin hydrocarbon gas component is similar to thermogenic gas and has a trend of a transition to oceanic hydrothermal system abiogenic gas. In addition, the deep Songliao Basin gas isotopic pattern is different from both Lost City and Kidd Creek where the deep Basin gas carbon isotopic pattern has a reverse order, and the hydrogen isotopic pattern has a normal order. …”
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Minor-merger-induced Star Formation Rejuvenation in an Elliptical Radio-loud Quasar Host, 3C 59 by Yijun Wang, Tao Wang, Ke Xu, Junjie Mao, Yerong Xu, Zheng Zhou

“…The three nearest satellite galaxies of 3C 59 exhibit significant morphological disturbances, and two of them present strong tidal tails pointing toward 3C 59. In addition, all the satellite galaxies within a projected distance of 200 kpc show low star formation activities. …”
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From canonical to unique: extension of a lipophilicity scale of amino acids to non-standard residues by Antonio Viayna, Paulina Matamoros, David Blázquez-Ruano, William J. Zamora

“…Conclusions: Overall, both models exhibit good correlations with the experimental values, with Model 1 showing lower statistical errors. In addition, our predictions were able to correctly predict the experimental hydrophobicity change due to the number of acetylated lysines in peptide pairs determined by HPLC, suggesting that our scale can be employed for proteomics studies that include post-translational modifications beyond acetylation.…”
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A High-resolution Spectroscopic Survey of Directly Imaged Companion Hosts. I. Determination of Diagnostic Stellar Abundances for Planet Formation and Composition by Aneesh Baburaj, Quinn M. Konopacky, Christopher A. Theissen, Sarah Peacock, Lori Huseby, Benjamin J. Fulton, Roman Gerasimov, Travis S. Barman, Kielan K. W. Hoch

“…The measurement of elemental abundances beyond carbon and oxygen also provides access to additional abundance ratios, such as Mg/Si, which could aid in further modeling of their giant companions.…”
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METTL3-dependent DLG2 inhibits the malignant progression of cervical cancer by inactivating the Hippo/YAP signaling by Mei Pu, Xia Xiao, Shasha Lv, Daqing Ran, Qian Huang, Mingming Zhou, Qirong Lei, Lingshuang Kong, Qing Zhang

“…Elevating DLG2 levels significantly suppressed cervical cancer cell proliferation, migration, and invasion, while promoting apoptosis. Additionally, DLG2 overexpression led to the deactivation of the Hippo/YAP signaling pathway. …”
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A Systematic Review and Meta-Analysis of Mapping Biopsy for Primary Extramammary Paget’s Disease in Reducing Recurrence Following Surgical Excision by Thirrisha Murugan, Louis Choon Kit Wong, MD, Xing-Yi Sarah Ong, MD, Sze Huey Tan, PhD, Joey Wee-Shan Tan, MSc, Ying Liu, PhD, Nicholas B. Shannon, PhD, MD, Jianbang Chiang, MBBS, MRCP, MMed, Eileen Poon, MBBS, MRCP, MMED, Jason Yongsheng Chan, MBBS, MRCP, MMed, FAMS, PhD, Valerie Shiwen Yang, MB BChir, PhD, MRCP, FAMS, Nagavalli Somasundaram, MBBS, MRCP, MMED, Mohamad Farid, MBBS, MRCP, MMed, Ru Xin Wong, MBBS, FRCR, Wen Long Nei, MBBS, FRCR, Jin Wei Kwek, MBBS, FRCR, FAMS, Choon Hua Thng, MBBS, FRCR, FAMS, Tiffany Hennedige, MBBS, FRCR, MMed, MCI, Po Yin Tang, BMEDSc, MBBS, FRCPath, FRCAPA, Sathiyamoorthy Selvarajan, MBBS, PGDCP, FRCPath, MCS, FAMS, Kae Jack Tay, MBBS, MRCS, MMed, MCI, FAMS, Mohamed Rezal Abdul, MB, BCh, BAO, LRCP&SI, MSurg, Jolene Si Min Wong, MBBS, MMed, FRCS, Chin Jin Seo, MB, BCh, BAO, MMed, FRCS, Khee Chee Soo, MBBS, MD, FRACS, FACS, Claramae Shulyn Chia, MBBS, MMed, FRCS, Chin-Ann Johnny Ong, MBBS, MMed, FRCS, PhD

“…A total of 12 studies were shortlisted for final analysis. 294 patients who underwent mapping biopsies and 48 patients who did not undergo mapping biopsies were included in the assessment. …”
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Statistical analysis plan for the LAST ACT clinical trial; a Leukotriene A4 hydrolase Stratified non-inferiority Trial of Adjunctive Corticosteroids for HIV-negative adults with Tu... by Joseph Donovan, Dong Huu Khanh Trinh, Ronald B. Geskus, Marcel Wolbers, Guy E. Thwaites, Nguyen Thuy Thuong Thuong, Le Thanh Hoang Nhat

“…The trial was an LTA4H genotype stratified, parallel group, randomised, double blind, placebo-controlled multi-centre Phase III trial of dexamethasone given for 6–8 weeks in addition to standard anti-tuberculosis drugs. LTA4H genotype (CC, CT, TT) was determined in all participants prior to randomisation; only those with CC or CT genotype were randomised to dexamethasone or placebo. …”
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Spondias purpurea L. (Anacardiaceae) fruits flours at different maturation stages: Drying kinetics, mathematical modelling, characterization and correlation analysis by Álvaro Gustavo Ferreira da Silva, Franciscleudo Bezerra da Costa, Ana Marinho do Nascimento, Giuliana Naiara Barros Sales, Jéssica Leite da Silva, Alzira Maria de Sousa Silva Neta, Wellington Souto Ribeiro, Toshik Iarley da Silva, Bruno Fonsêca Feitosa

“…Additionally, an assessment of the resulting flours' quality was conducted. …”
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Combined exposure to mixed brominated flame retardants on obstructive sleep apnea syndrome in US adults by Junping Liu, Zhaoyue Liu, Xinru Liu, Nan Wang, Lin Wu, Xiaoxue Xu, Wei Liu, Yajie Feng, Huanyu Zhang, Yue Zhou, Xinle Yin, Yaping Liu, Qunhong Wu, Ning Ning, Libo Liang

“…PBB153 was determined to be the most weighted BFRs. Additionally, RCS regression model also verified the strong non-linear relationship that existed between OSAS risk and PBB153. …”
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A dataset on environmental DNA, bacterio-, phyto- and zooplankton from an emerging periglacial lagoon in Svalbard, ArcticMendeley DataMendeley Data by Sergej Olenin, Dzmitry Lukashanets, Anastasija Zaiko, Aurelija Samuilovienė, Irina Olenina, Evelina Grinienė, Tobia Politi, Aleksej Šaškov, Greta Kilmonaitė, Andrius Šiaulys

“…In these emerging water bodies, new ecosystems are formed, consisting of elements presumably entering the lagoon from the melting glacier, the surrounding tundra water bodies and the coastal ocean. …”
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Spatio-temporal Distribution of Aboveground Forest Biomass and Carbon in Tropical Dry Forest under Anthropogenic Pressure, Brazil by Gabriela Salami, Rinaldo Luiz Caraciolo Ferreira, José Antônio Aleixo da Silva, Fernando José Freire, Emanuel Araújo Silva, Marco Antonio Diodato, Dhonatan Diego Pessi

“…This investigation seeks to elucidate these dynamics and provide insights for management and conservation strategies based on robust empirical data, in addition to answering the following questions: Does the history of anthropogenic interventions in Dry Tropical Forest areas cause variations in the spatial distribution of biomass and carbon stocks that can be detected by the kriging method? …”
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Sulfated Cyclocarya paliurus polysaccharides exert immunomodulatory potential on macrophages via Toll-like receptor 4 mediated MAPK/NF-κB signaling pathways by Yue Yu, Haibin Zhu, Mingyue Shen, Qiang Yu, Yi Chen, Shiru Mo, Jianhua Xie

“…Meanwhile, SCP3 could activate mitogen-activated protein kinase (MAPK) and nuclear factor kappa B (NF-κB) signaling pathways, which increased the phosphorylation of Erk1/2, JNK, p38 and NF-κB p65, promoting secretion of cytokines tumor necrosis factor α (TNF-α), interleukin 6 (IL-6) and nitric oxide (NO) as well as the production of reactive oxygen species (ROS). In addition, Toll-like receptor 4 (TLR4) receptor inhibitors were able to block the production of NO and TNF-α by SCP3-stimulated macrophages. …”
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Unveiling the potential of Nd2O3 in optimizing the radiation shielding performance of B2O3–TiO2–BaO–ZnO-Nd2O3 glasses by Maryam Al Huwayz, Aljawhara H. Almuqrin, F.F. Alharbi, M.I. Sayyed, B. Albarzan

“…Introducing Nd2O3 increases the glasses' LAC, suggesting enhanced radiation shielding performance. Also, Nd2O3 addition influences the HVL within the glasses, with higher content reducing the HVL. …”
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Combined effects of co-exposure to microcystin-LR and polystyrene microplastics on growth, brain pathology and thyroid hormone homeostasis in adult zebrafish by Wang Lin, Ling Liao, Ling Ling, Huimin Luo, Ying Jiang, Xinru Li, Yilong Yao, Pinhong Yang

“…The concurrent presence of algal blooms and microplastics pollution in natural water bodies poses a novel threat. However, the joint effects of microcystin-LR (MCLR) in combination with polystyrene microplastics (PSMPs) on the thyroid endocrine system of adult fish remains unclear. …”
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Nomogram model and risk score predicting overall survival and guiding clinical decision in patients with Hodgkin’s lymphoma: an observational study using SEER population-based data... by Yue Yang, Shang Li, Xiao Zhu, Yi Kong, Mingtao Zhang, Xiangping Liang, Zherui Zhang, Shuzhen Tan, Yingqi Li, Yueyuan Zhong, Yingqi Shao, Jiayi Xu, Zesong Li

“…The predictive ability of the nomogram was validated by the Concordance Index. Additionally, the calibration curve and receiver operating characteristic curve were implemented to evaluate the accuracy and discrimination. …”
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