Dietary γ-Aminobutyric Acid Promotes Growth and Immune System Performance and Improves Erythropoiesis and Angiogenesis in Gibel Carp (<i>Carassius auratus gibelio</i>) by Xinlan Bai, Lu Zhang, Hualiang Liang, Dongyu Huang, Mingchun Ren, Haifeng Mi

“…In addition, 527 mg/kg (G3) and 602 mg/kg (G4) of GABA significantly increased the total antioxidant capacity (T-AOC). …”
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Molecular genetic and bacteriological methods of bovine mycoplasmosis diagnosis by E. V. Remizova, A. V. Gorbatov, L. K. Semina, Z. A. Skulyabina, N. V. Shmidt, G. A. Baldicheva, N. N. Avduevskaya

“…Real-time polymerase chain reaction is undoubtedly the most accurate and rapid diagnostic method for mycoplasmosis, but a preliminary diagnosis can also be established bacteriologically within 2–7 days. In addition, during microbiological testing, it is possible to assess the antibiotic resistance of mycoplasma isolates, thereby developing an optimal and high-quality scheme of the disease treatment and prevention.…”
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Challenges and Novelties in the Treatment of Obesity in Adults. A review by Karolina Kuczapska, Marek Kurowski, Anna Gliwa, Monika Ryglewicz, Dariusz Fabian, Elżbieta Leszczyńska-Knaga, Natalia Jakubczyk, Weronika Rutkowska-Kawalec, Paweł Moczydłowski, Karolina Michalczuk

“…Results Nowadays, pharmacotherapy can offer GLP-1 receptor agonists like liraglutide or semaglutide, and new drugs like tirzepatide that show great effectiveness. Additionally, bariatric surgery continues to offer great solution for severe obesity, combining restrictive and malabsorptive mechanisms for significant weight loss and metabolic benefits. …”
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Multi-trace elements-enriched functional drink accelerates gastric ulcer repair via the HGF/c-Met/STAT3 pathway by Yongnan Piao, Nuoya Wang, Mingji Jin, Jianyu Piao, Mingfeng Han, Zifei Wang, Chunhua Quan, Jishan Yin, Zhonggao Gao, Wenxiang Cui, Shuangqing Wang, Xiuquan Quan

“…Finally, FD reduced the severity of gastric mucosal injury caused by invasive factors, improved the morphological structure of gastric mucosal cells, enhanced the ability of oxidative stress, and inhibited excessive inflammatory response. In addition, the combination of OME and FD-L did not significantly affect the therapeutic efficacy of OME, but reduced its adverse effects. …”
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De novo assembly of the complete mitochondrial genomes of two Camellia-oil tree species reveals their multibranch conformation and evolutionary relationships by Zhun Xiao, Yiyang Gu, Junqin Zhou, Mengqi Lu, Jinfeng Wang, Kaizheng Lu, Yanling Zeng, Xiaofeng Tan

“…This sheds light on mitogenome structural complexities and contributes to our understanding of evolutionary processes. Additionally, these results enrich Camellia genetic resources and expand our knowledge of mitogenome variation.…”
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Engineering of l-threonine and l-proline biosensors by directed evolution of transcriptional regulator SerR and application for high-throughput screening by Wei Pu, Jinhui Feng, Jiuzhou Chen, Jiao Liu, Xuan Guo, Lixian Wang, Xiaojia Zhao, Ningyun Cai, Wenjuan Zhou, Yu Wang, Ping Zheng, Jibin Sun

“…In this study, a novel transcriptional regulator-based biosensor for l-threonine and l-proline was successfully developed, inspired by our new finding that SerE can export l-proline in addition to the previously known l-threonine and l-serine. …”
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Infections with Giardia duodenalis and Entamoeba histolytica/Entamoeba dispar as Hidden and Prevalent Conditions in Periurban Communities in the State of Rio de Janeiro, Brazil by Deiviane A. Calegar, Kerla J. L. Monteiro, Andressa B. Gonçalves, Márcio N. Boia, Lauren H. Jaeger, Beatriz C. Nunes, Filipe A. Carvalho-Costa

“…This difference was also significant for infection with any pathogenic parasite (43/187 (23%) vs. 40/272 (14/7%); PR = 1.56; 95% CI = 1.06–2.30; p=0.026). In addition, people residing in houses with more than four inhabitants showed significantly higher positivity for infections with G. duodenalis and with E. histolytica/E. dispar (22/138 (15.9%) vs. 16/311 (5.1%); PR = 3.09; 95% CI = 1.68–5.71; p<0.001 for G. duodenalis and 32/138 (23.2%) vs. 30/311 (9.6%); PR = 2.40; 95% CI = 1.52–3.79; p<0.001 for E. histolytica/E. dispar). …”
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Lymphocyte Oxidative Stress/Genotoxic Effects Are Related to Serum IgG and IgA Levels in Coke Oven Workers by Meili Gao, Yongfei Li, Aqun Zheng, Xiaochang Xue, Lan Chen, Yu Kong

“…Except for age, alcohol and smoking status, IgM, and IgE, a significant correlation in urinary 1-OHP and other biomarkers in the total population was observed. Additionally, a significant negative correlation in genotoxic/oxidative damage biomarkers of MDA, 8-OH-dG, CTL levels, and immunoglobins of IgG and IgA levels, especially in coke oven workers, was found. …”
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Deciphering the Transcriptional Metabolic Profile of Adipose-Derived Stem Cells During Osteogenic Differentiation and Epigenetic Drug Treatment by Giulia Gerini, Alice Traversa, Fabrizio Cece, Matteo Cassandri, Paola Pontecorvi, Simona Camero, Giulia Nannini, Enrico Romano, Francesco Marampon, Mary Anna Venneri, Simona Ceccarelli, Antonio Angeloni, Amedeo Amedei, Cinzia Marchese, Francesca Megiorni

“…RG108-treated cells, in addition to the upregulation of the osteogenesis-related markers RUNX2 and ALPL, showed statistically significant alterations in genes implicated in transcriptional control (MYCN, MYB, TP63, and IRF1), ethanol oxidation (ADH1C, ADH4, ADH6, and ADH7), and glucose metabolism (SLC2A3). …”
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Innovative strategies for valorization of byproducts from soybean industry: A review on status, challenges, and sustainable approaches towards zero-waste processing systems by Ahasanul Karim, Emmanuel Freddy Osse, Seddik Khalloufi

“…Various commercially viable products derived from repurposing the carbohydrate and protein fractions of diverse soy byproducts are highlighted. Additionally, a cutting-edge framework is proposed, advocating for the establishment of a zero-waste system within the soybean processing sector, emphasizing integrated biorefinery technologies, circular economy strategies, and sustainability principles. …”
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An environmental isolate of Pseudomonas, 20EI1, reduces Aspergillus flavus growth in an iron-dependent manner and alters secondary metabolism by Elizabeth M. Wyman, W. Scott Grayburn, Matthew K. Gilbert, Matthew D. Lebar, Jessica M. Lohmar, Jeffrey W. Cary, Thomas J. C. Sauters, Antonis Rokas, Ana M. Calvo

“…Furthermore, we determined that this growth inhibition is iron-dependent. In addition, Pseudomonas 20EI1 reduced or blocked the production of aflatoxin, as well as cyclopiazonic acid and kojic acid. …”
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Therapeutic Effects of BCG Vaccination on Type 1 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Yu-Chen Chang, Chien-Ju Lin, Yu-Hsuan Hsiao, Yu-Han Chang, Shu-Jung Liu, Hsin-Yin Hsu

“…There is no robust evidence to support the use of the BCG vaccine for the treatment of T1DM although the HbA1c levels tended to improve. Additional RCTs to assess the long-term effects of the BCG vaccine on glycemic control are warranted.…”
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A backwater technology for enhancing pollutants discharge from aquaculture tanks in a Litopenaeus vannamei recirculating aquaculture system: Performance and control models by Jianping Xu, Yishuai Du, Jiawei Zhang, Fudi Chen, Li Zhou, Tianlong Qiu, Jianming Sun

“…Under the action of IEB, the yield of shrimp increased by 4.48 %, with energy consumption accounting for only 0.74 % of the RAS operational energy consumption. Additionally, the relationship between the working time of the IEB device (TIEB) and the backwashing cycle of the Microscreen drum filter (TMDF) was studied, and a relevant model was established. …”
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Judicious Molecular Design of 5H‑Dithieno[3,2‑b:2′,3′‑d]Pyran‐based Hole‐Transporting Materials for Highly Efficient and Stable Perovskite Solar Cells by Kun‐Mu Lee, Chia‐Hui Lin, Chia‐Chi Chang, Ting‐Yu Yang, Wei‐Hao Chiu, Wei‐Chen Chu, Ya‐Ho Chang, Sie‐Rong Li, Shih‐I Lu, Hsiao‐Chi Hsieh, Kang‐Ling Liau, Chia Hui Hu, Chih‐Hung Chen, Yun‐Shuo Liu, Wei‐Chun Chou, Mandy M. Lee, Shih‐Sheng Sun, Yu‐Tai Tao, Yan‐Duo Lin

“…As a result, PSCs employing CF3‐mF and CF3‐oF gave impressive PCEs of 23.41 and 24.13%, respectively. In addition, the large‐area (1.00 cm2) PSCs based on CF3‐oF achieved a PCE of 22.31%. …”
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Reduction of IL-17A Might Suppress the Th1 Response and Promote the Th2 Response by Boosting the Function of Treg Cells during Silica-Induced Inflammatory Response In Vitro by Wen Tang, Fangwei Liu, Ying Chen, Laiyu Song, Wujing Dai, Chao Li, Dong Weng, Jie Chen

“…The Th1 response was suppressed and the Th2 response was promoted by the addition of anti-IL-17A mAb or IL-1Ra. IL-1Ra treatment decreased the level of IL-6, whereas the levels of IL-23 and ROR-γt were increased. …”
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The variability and predictability of summer southwest monsoon intensity measurement index across mainland indochina: from local synoptic to large scale perspectives by Kyaw Than Oo, Yinshuo Dong, Kazora Jonah

“…Our analysis reveals strong correlations between the SMII and regional rainfall patterns, particularly during the peak intensity of the summer months. Additionally, significant associations with El Niño Southern Oscillation (ENSO) indices and the eastern Indian Ocean suggest potential teleconnections, which can enhance predictive capabilities. …”
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Smart phone-based transcutaneous electrical acupoint stimulation as adjunctive therapy for hypertension (STAT-H trial): protocol for a cluster randomised controlled trial by Yu Wang, Xiao Wang, Ying Lin, Chao-Qun Yan, Guang-Xia Shi, Cun-Zhi Liu, Jing-Wen Yang, Jian-Feng Tu, Shi-Yan Yan, Xin-Tong Su, Li-Qiong Wang, Si-Bo Kang, Bao-Hong Mi, He-Wen Li, Xue-Zhou Wang

“…Tertiary outcomes will include change in body mass index, change in waist circumference, physical activity and medication adherence. …”
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L-Cysteine Treatment Delays Leaf Senescence in Chinese Flowering Cabbage by Regulating ROS Metabolism and Stimulating Endogenous H₂S Production by Linzhi Gan, Zhenliang Mou, Jianye Chen, Wei Shan, Jianfei Kuang, Wangjin Lu, Yating Zhao, Wei Wei

“…L-cys treatment also maintained a higher total antioxidant capacity and scavenging rate of •OH and O₂^•−. Additionally, L-cys treatment maintained high levels of ascorbate and glutathione and activated antioxidant enzymes (superoxide dismutase, peroxidase, and catalase) and the expression of the encoding genes. …”
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Associations of Voice Metrics with Postural Function in Parkinson’s Disease by Anna Carolyna Gianlorenço, Valton Costa, Walter Fabris-Moraes, Paulo Eduardo Portes Teixeira, Paola Gonzalez, Kevin Pacheco-Barrios, Ciro Ramos-Estebanez, Arianna Di Stadio, Mirret M. El-Hagrassy, Deniz Durok Camsari, Tim Wagner, Laura Dipietro, Felipe Fregni

“…The regression analysis showed that CPPS is associated with posture (UPDRS-III posture scores: β = −0.196; F = 10.0; <i>p</i> = 0.01; R² = 0.50) and UPDRS-III postural stability scores (β = −0.130; F = 5.57; <i>p</i> = 0.04; R² = 0.35). Additionally, the associations between CPPS and rapid alternating movement (β = −0.297; <i>p</i> = 0.07), rigidity (β= −0.36; <i>p</i> = 0.11), and body bradykinesia (β = −0.16; <i>p</i> = 0.13) showed a trend towards significance. …”
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Managing cognitive impairment in patients with chronic obstructive pulmonary disease (COPD) in Saudi Arabia: what are the current practices? by Rayan A. Siraj, Ahmed M. Alrajeh, Mushabbab A. Alahmari, Fahad H. Alahmadi, Abdulelah M. Aldhahir, Abdullah A. Alqarni, Jaber S. Alqahtani, Saeed M. Alghamdi, Turki M. Alanazi, Abdullah Alruwaili, Saleh S. Algarni, Abdulrhman S. Alghamdi, Tawah H. Alsindi, Mohammed M. Alyami, Faisal A. Alshehri, Talal Alshammari, Rehab Alhasani, Khalid Alrashed, Nawaf E. Sabir, Ataa F. Mesbah

“…Although the vast majority of physicians reported that cognitive impairment leads to underestimation of COPD severity (85%) and interferes with self-management (85%), only 11% agreed on the important role of screening. In addition, only half of the study participants aimed to identify possible cognitive impairment, with only 4% screening for cognitive impairment during patients’ assessment. …”
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