How fast is the frequency of precipitation extremes doubling in global land regions? by Guillaume Chagnaud, Juliette Blanchet, Guillaume Evin, Benoit Hingray, Thierry Lebel, Geremy Panthou, Théo Vischel

“…The fastest frequency doubling, in the coming two decades, is found in the highly vulnerable tropical regions of Western and South Eastern Africa, with strong implications for hydrological risk management there. In addition, the rarest events are found to have smaller FDT compared to more ‘common’ extremes; infrastructures designed to withstand the strongest events are thus more exposed to premature obsolescence.…”
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High-performance UWB Vivaldi antenna on FR4: A cost-effective solution for wearable technologies by Sahar Saleh, Tale Saeidi, Nick Timmons, Bader Alali, Faroq Razzaz, Ayman A. Althuwayb

“…The antenna's suitability for wearable applications was validated through testing on flat and curved human phantoms made of skin, fat, and muscle, showing low Specific Absorption Rate (SAR) values across the UWB spectrum, confirming its safety for body-centric use. Measured results include S11 values below -10.56 dB over the 3.66–20.42 GHz range, a peak gain of 8.1 dBi, stable radiation patterns, and an average group delay of 0.83 ns. …”
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The RNA M5C methyltransferase NSUN2 promotes progression of hepatocellular carcinoma by enhancing PKM2-mediated glycolysis by Qin Qi, Rui Zhong, Yan Huang, Yong Tang, Xiao-wen Zhang, Chang Liu, Chun-fang Gao, Lin Zhou, Jian Yu, Lu-yi Wu

“…Specifically, NSUN2 could stabilize PKM2 mRNA by increasing the m5C level of the m5C site C773 in the 3′-UTR of PKM2 mRNA. In addition, rescue assays revealed that NSUN2 promotes HCC glycolysis and progression by upregulating PKM2. …”
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Effect of Interleukin-17 in the Activation of Monocyte Subsets in Patients with ST-Segment Elevation Myocardial Infarction by Montserrat Guadalupe Garza-Reyes, Mónica Daniela Mora-Ruíz, Luis Chávez-Sánchez, Alejandra Madrid-Miller, Alberto Jose Cabrera-Quintero, José Luis Maravillas-Montero, Alejandro Zentella-Dehesa, Luis Moreno-Ruíz, Selene Pastor-Salgado, Erick Ramírez-Arias, Nataly Pérez-Velázquez, Adriana Karina Chávez-Rueda, Francisco Blanco-Favela, Wendy Guadalupe Vazquez-Gonzalez, Alicia Contreras-Rodríguez

“…A gradual increase in IL-17 was found in STEMI and post-STEMI patients. Additionally, IL-17 had a powerful effect on the recruitment of CD14++CD16+/CD14+CD16++ monocytes derived from patients post-STEMI compared with the monocytes from patients with STEMI, suggesting that IL-17 recruits monocytes with inflammatory activity post-STEMI. …”
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Effect of cooling medium temperature on cooling curve and microstructure of Ti65 alloy by DONG Xiaolin, LI Wenyuan, TAN Haibing, LIU Jianrong, LIU Qiaomu, CHEN Yulong, WANG Lei, WANG Qingjiang

“…When the oil temperature rises to 80 ℃， the vapor stage disappears. In addition， the microstructure shows a transition trend from α+β dual-phase microstructure to martensitic microstructure with the increase in oil temperature. …”
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Boosting disassembly of π–π stacked supramolecular nanodrugs under tumor microenvironment by introducing stimuli‐responsive drug‐mates by Wenzhe Xu, Ruixu Yang, Yingke Xue, Yang Chen, Shuwei Liu, Songling Zhang, Yonggang Wang, Yi Liu, Hao Zhang

“…Meaningfully, the ΔEdis is the sum of a series of activation energy according to the specific stimuli of TME. …”
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Evaluating a large language model’s ability to answer clinicians’ requests for evidence summaries by Mallory N. Blasingame, Taneya Y. Koonce, Annette M. Williams, Dario A. Giuse, Jing Su, Poppy A. Krump, Nunzia Bettinsoli Giuse

“…However, many included references could not be independently verified, and attempts were not made to assess whether any additional concepts introduced by aiChat were factually accurate. …”
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Modeling the influence of external heat flux on thermal characteristics of the silica aerogel/paraffin in a cylindrical atomic duct by Lishan Geng, Ali B.M. Ali, Shahram Babadoust, Anjan Kumar, Barno Abdullaeva, Rasha Abed Hussein, Soheil Salahshour, Sh Esmaeili

“…This research explored how external heat flux affected the behavior of a tube filled with silica aerogel and phase change materials. Additionally, we incorporated CuO nanoparticles to evaluate their impact on the system. …”
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LMF-Net: A Learnable Multimodal Fusion Network for Semantic Segmentation of Remote Sensing Data by Jihao Li, Wenkai Zhang, Weihang Zhang, Ruixue Zhou, Chongyang Li, Boyuan Tong, Xian Sun, Kun Fu

“…The further mining for cross-modal features is comparatively insufficient in heterogeneous data fusion. In addition, complex structures also lead to relatively heavy computation burden. …”
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Robotic pedicle screw placement for minimal invasive thoracolumbar spine surgery: a technical note by Luthfi Gatam, Luthfi Gatam, Luthfi Gatam, Phedy Phedy, Phedy Phedy, Syafruddin Husin, Harmantya Mahadhipta, Asrafi Rizki Gatam, Asrafi Rizki Gatam, Asrafi Rizki Gatam, Mitchel Mitchel, Karina Sylvana Gani, Erica Kholinne, Erica Kholinne

“…It also covers the surgical process, including patient positioning, dynamic reference placement, intraoperative cone-beam tomography, screw planning, exposure, and insertion techniques for spinal stabilization.DiscussionA meta-analysis highlighted the significant advantages of robotic spine surgery over traditional freehand techniques, including a notably lower complication rate (4.83% vs. 14.97%) and up to a tenfold reduction in surgeon radiation exposure compared to fluoroscopy. Additionally, robotic systems enhance pedicle screw placement accuracy, achieving a 91.7% success rate. …”
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The sulfur-related metabolic status of Aspergillus fumigatus during infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal target by Reem Alharthi, Monica Sueiro-Olivares, Isabelle Storer, Hajer Bin Shuraym, Jennifer Scott, Reem Al-Shidhani, Rachael Fortune-Grant, Elaine Bignell, Lydia Tabernero, Michael Bromley, Can Zhao, Jorge Amich

“…Indeed, the role of 5 of the 15 genes has previously been empirically validated, supporting the likelihood that the remaining candidates are relevant. In addition, the analysis of gene expression dynamics at early (16 h), mid (24 h), and late (72 h) time-points uncovered potential disease initiation and progression factors. …”
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Toward a hyperventilation detection system in freediving: a proof of concept using force sensor technology by Frank Pernett, Frank Pernett, Eric Mulder, Filip Johansson, Arne Sieber, Arne Sieber, Ricardo Bermudez, Marcus Lossner, Erika Schagatay, Erika Schagatay

“…The divers were instructed to breathe normally and perform three dry apneas of 1, 2, and 3-min duration at 2-min intervals in a sitting position. …”
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Effect of sleep quality on the severity of perimenstrual symptoms in Japanese female students: a cross-sectional, online survey by Yukio Urabe, Makoto Komiya, Noriaki Maeda, Satoshi Arima, Tsubasa Tashiro, Rami Mizuta, Sakura Oda, Takaaki Nagasawa, Koichi Naito

“…The MDQ scores were compared between two groups (normal-sleep quality and low-sleep quality) using Mann-Whitney U test. In addition, multiple logistic regression analysis was performed, and the MDQ subscales that showed significant differences between the groups were used as independent variables. …”
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Primary aldosteronism patients with previous cardiovascular and cerebrovascular events have high aldosterone responsiveness to ACTH stimulation by Eriko Nakano, Kosuke Mukai, Atsunori Fukuhara, Michio Otsuki, Iichiro Shimomura, Takamasa Ichijo, Mika Tsuiki, Norio Wada, Takashi Yoneda, Yoshiyu Takeda, Kenji Oki, Tetsuya Yamada, Yoshihiro Ogawa, Daisuke Yabe, Miki Kakutani, Masakatsu Sone, Takuyuki Katabami, Akiyo Tanabe, Mitsuhide Naruse, JPAS/JRAS Study Group

“…Aldosterone secretion in primary aldosteronism (PA) is often regulated by adrenocorticotropic hormone (ACTH) in addition to its autonomous secretion. However, the clinical characteristics and risk of cardiovascular and cerebrovascular (CCV) events in PA patients with aldosterone responsiveness to ACTH stimulation remain unclear. …”
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Metal Biomonitoring Through Arboreal Species in Riparian Ecosystems: <i>Pithecellobium dulce</i> as a Bioindicator Species by Sayuri Hernández-Maravilla, María Luisa Castrejón-Godínez, Efraín Tovar-Sánchez, Hugo Albeiro Saldarriaga-Noreña, Alexis Rodríguez, Marcos Eduardo Rosas-Ramírez, Patricia Mussali-Galante

“…<i>P. dulce</i> registered high levels of Cu, Pb, and Zn in both leaf and bark, showing higher concentrations in leaf than in bark. In addition, the greater the concentration of Pb in leaves, the greater the genotoxic damage observed, while the concentration of Cu and Zn did not show a relationship with the genotoxic damage in leaves. …”
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Mosquito‐derived ingested DNA as a tool for monitoring terrestrial vertebrates within a peri‐urban environment by Christine Chivas, Adam Stow, Andrew Harford, Thomas J. Mooney, David Loewensteiner, Kate Montgomery, Anthony Chariton

“…The overall diversity retrieved reveals a broad diversity of species with 10 avian taxa and six mammalian taxa, including both native and non‐native species of varying body sizes and behavioral characteristics. Both the multi‐locus approach and the use of a human blocking primer revealed additional diversity. …”
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Optimizing winged-bean meal through oven and autoclave heating as viable alternative for plant-based aquafeed by Shobrina Silmi Qori Tartila, Tholibah Mujtahidah, Muh. Azril, Anjali Apta Pramudita, Lusi Septiani, Bagas Putra Satria, Ignatius Abel Cristanto, Muhammad Abizar Sakti Oktavian, Sultan Jibran Risqulloh, Santika Dewi Astuti

“…Heating treatments improved in vitro trypsin activity (1300 units/O and 1135 units/A vs. 835 units) but reduced protein (29.05±1.96%/A and 31.73±1.52%/O vs. 35.17±0.38%) and moisture contents. Additionally, the O treatment met the standards for aquafeed protein content (27-45%) and potentially fulfilled the protein requirements for catfish (25-40%), Nile tilapia (30-35%), and Java barb (30-32%). …”
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Study of Long-term Spectral Evolution and X-Ray and γ-Ray Correlation of Blazars Seen by HAWC by R. Alfaro, C. Alvarez, A. Andrés, J.C. Arteaga-Velázquez, D. Avila Rojas, H.A. Ayala Solares, R. Babu, E. Belmont-Moreno, A. Bernal, K.S. Caballero-Mora, T. Capistrán, A. Carramiñana, F. Carreón, S. Casanova, U. Cotti, J. Cotzomi, S. Coutiño de León, E. De la Fuente, D. Depaoli, N. Di Lalla, R. Diaz Hernandez, B.L. Dingus, M.A. DuVernois, M. Durocher, J.C. Díaz-Vélez, K. Engel, C. Espinoza, K.L. Fan, N. Fraija, S. Fraija, J.A. García-González, F. Garfias, A. Gonzalez Muñoz, M.M. González, J.A. Goodman, S. Groetsch, J.P. Harding, S. Hernández-Cadena, I. Herzog, D. Huang, F. Hueyotl-Zahuantitla, A. Iriarte, V. Joshi, S. Kaufmann, D. Kieda, A. Lara, W.H. Lee, J. Lee, H. León Vargas, J.T. Linnemann, A.L. Longinotti, G. Luis-Raya, K. Malone, O. Martinez, I. Martinez-Castellanos, J. Martínez-Castro, J.A. Matthews, P. Miranda-Romagnoli, J.A. Montes, E. Moreno, M. Mostafá, A. Nayerhoda, L. Nellen, M.U. Nisa, R. Noriega-Papaqui, N. Omodei, M. Osorio, Y. Pérez Araujo, E.G. Pérez-Pérez, C.D. Rho, D. Rosa-González, E. Ruiz-Velasco, H. Salazar, D. Salazar-Gallegos, A. Sandoval, M. Schneider, J. Serna-Franco, A.J. Smith, Y. Son, R.W. Springer, O. Tibolla, K. Tollefson, I. Torres, R. Torres-Escobedo, R. Turner, F. Ureña-Mena, E. Varela, L. Villaseñor, X. Wang, I.J. Watson, K. Whitaker, E. Willox, S. Yun-Cárcamo, H. Zhou, C. de León, HAWC collaboration, Abraham D. Falcone, Fredric Hancock

“…For Mrk 501, we found evidence of a long-term correlation. Additionally, we identified a period in the light curve where the flux was very low for more than 2 yr. …”
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Heteronemin Suppresses Lymphangiogenesis Through ARF-1 and MMP-9/VE-Cadherin/Vimentin by Hsien-Lin Chen, Yu-Chieh Su, Huang-Chi Chen, Jui-Hsin Su, Chang-Yi Wu, Shih-Wei Wang, In-Pin Lin, Chung-Yi Chen, Chien-Hsing Lee

“…Mechanistically, SP-1 induced the cell cycle arrest of LECs in the G0/G1 phase and reduced the downstream of VEGFR-3, such as phosphorylated MEK/ERK and NF-κB. In addition, SP-1 inhibited LECs’ tubulogenesis and migration through the ARF-1 and MMP-9/VE-cadherin/vimentin. …”
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Oral dydrogesterone versus oral micronized progesterone in threatened miscarriage: protocol paper for a randomized controlled trial by Alka Kriplani, Gouri Shankar Kamilya, T Ramani Devi, Ashima Taneja, Amol Pawar, Gayathri Karthik Nagesh, Tapan Pattanaik, Tanusree Gupta, Mahima Jain, Monjori Mitra

“…Scheduled visits after enrollment will be conducted during 6–13, 8–14, 18–20 and 24–26 weeks of gestation, in addition to a visit at the end of treatment at 14 weeks and another after parturition. …”
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