Case report: The Montgomery T tube may be the preferred transition option for achieving a smooth extubation after tracheotomy when complicating airway pathology is present by Jieqiong Wang, Xun Li, Weihua Xu, Nenghui Jiang, Bo Yang, Ming Chen

“…To tackle these issues concurrently while aiming for swift tube removal, we performed bronchoscopic intervention for granulation tissue excision, subsequently replacing the conventional tracheostomy tube with a Montgomery T tube as a transitional measure to restore normal ventilation. With additional rehabilitation fostering respiratory function enhancement, follow-up bronchoscopies confirmed no recurrence of granulations and significant reduction in laryngeal edema, thereby enabling the successful removal of the Montgomery T tube 2 months later, restoring the patient’s unassisted respiratory capacity. …”
Get full text

Assessment of the Effectiveness of Fascial Manipulation in Patients with Degenerative Disc Disease of the Lumbosacral Spine by Anna Mikołajczyk-Kocięcka, Marek Kocięcki, Lech Cyryłowski, Aleksandra Szylińska, Paweł Rynio, Magdalena Gębska, Ewelina Szuba, Jarosław Kaźmierczak

“…<b>Conclusion:</b> Fascial Manipulation is an effective method for treating pain in patients with disc herniations of the lumbar spine; in addition to reducing pain, it improves the range of motion and the results of SLR and PKB tests. …”
Get full text

Ethephon and Diethyl Aminoethyl Mixture (EDAH) Reduces Maize Lodging and Enhances Overall Productivity in Maize/Peanut Intercropping by Xiaojin Zou, Jiayi Xu, Huasen Xu, Liang Gong, Lizhen Zhang, Ying Wang, Liangshan Feng, Zhanxiang Sun

“…Maize lodging in the intercropping system with EDAH decreased by 48.7%. Additionally, EDAH-treated maize in the intercropping system exhibited a 12.1% reduction in plant height and a 27.7% reduction in ear height compared to untreated maize. …”
Get full text

Real-World Experience with AGA Guidelines in the Management of Crohn’s Disease following Ileocolonic Resection: A Retrospective Cohort Study by Shasha Tang, Wei Liu, Weilin Qi, Tunan Yu, Qian Cao, Xiaolong Ge, Wei Zhou

“…Cox regression showed that smoking at the time of surgery and AGA guideline adherence were independent factors associated with PER (HR: 3.75, 95% CI: 1.36-10.33, P=0.01; HR: 0.36, 95% CI: 0.15-0.86, P=0.02). In addition, further investigation revealed that educational background was the main factor related to patients’ nonadherence to AGA guidelines. …”
Get full text

Acupuncture mediates the “gut–testis axis” to improve asthenozoospermia by Jianheng Hao, Jianheng Hao, Huichao Xu, Boya Chang, Jia Ren, Haijun Wang, Laixi Ji, Laixi Ji

“…Real-time PCR, a western blot analysis, and immunofluorescence techniques were used to assess the effects of acupuncture on the gut barrier and blood–testis barrier functions. In addition, gut microbiome and metabolomics were used to study the impact of acupuncture on the gut microbiota structure, serum, and testicular metabolites in asthenozoospermic mice. …”
Get full text

Crop protection by RNA interference: a review of recent approaches, current state of developments and use as of 2013 by Kirsten Germing, Cecilia Andrea Díaz Navarrete, Andreas Schiermeyer, Udo Hommen, Luise Zühl, Sebastian Eilebrecht, Elke Eilebrecht

“…In total, RNAi applications for more than 30 different pest species were identified, most of which belonged to the insect orders Lepidoptera, Hemiptera and Coleoptera. In addition, applications targeting fungi and viruses were found. …”
Get full text

Progress towards 90-90-90 and 95-95-95 strategy implementations and HIV positivity trends in the City of Johannesburg by J C Y Nyasulu, I Maposa

“…HIV access trends were tracked and compared with the set strategy implementation targets. In addition, the HIV positivity rate was analysed to observe trends. …”
Get full text

miR-126 Mimic Counteracts the Increased Secretion of VEGF-A Induced by High Glucose in ARPE-19 Cells by Roberta Sanguineti, Alessandra Puddu, Massimo Nicolò, Carlo Enrico Traverso, Renzo Cordera, Giorgio L. Viviani, Davide Maggi

“…These results indicate that reduced levels of miR-126 may contribute to DR progression by increasing expression of VEGF-A in RPE cells. In addition, we provide evidence that upregulation of miR-126 in RPE cells counteracts the rise of VEGF-A secretion induced by hyperglycemia. …”
Get full text

Low-Grade Endometrial Stromal Sarcoma: A Case Report of a Rare Uterine Malignancy Mimicking Degenerative Uterine Leiomyoma in a Nulliparous Woman by Hyun Kyung Lee, Weon Jang, Kyoung Min Kim, Ji Soo Song

“…Characteristic findings on magnetic resonance imaging T2-weighted imaging (T2WI)—including intra-tumoral low signal intensity (SI) bands (correlating with preserved myometrial bundles separated by tumor cells on histopathology), cystic/necrotic changes, and absence of a speckled appearance—have been significantly associated with LGESS. Additionally, apparent diffusion coefficient mapping can aid in the characterization of uterine masses. …”
Get full text

Safety of a change of specifications of phytosterols/phytostanols as a novel food pursuant to Regulation (EU) 2015/2283 by EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Karen Ildico Hirsch‐Ernst, Ángeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Margarita Aguilera‐Gómez, Francesco Cubadda, Thomas Frenzel, Marina Heinonen, Monika Neuhäuser‐Berthold, Helle Katrine Knutsen, Morten Poulsen, Miguel Prieto Maradona, Josef Rudolf Schlatter, Alexandros Siskos, Henk vanLoveren, Wolfgang Gelbmann, Harry J. McArdle

“…The Panel also notes the history of multiple safety assessments of phytosterols performed by Member States and EFSA, in addition to the group ADI established by JECFA. The Panel also considers that an increase from less than 3 to less than 7% for the maximum specification limit for ‘other phytosterols’ is of no relevance regarding nutritional considerations. …”
Get full text

Cost-effectiveness analysis of pembrolizumab plus chemotherapy versus chemotherapy in untreated advanced pleural mesothelioma in the Chinese healthcare system by Wenwang Lang, Yulong He, Changchun Hou, Hua Li, Qinling Jiang, Liuyong Mei

“…To manage the uncertainty in the model, both probabilistic sensitivity analysis (PSA) and one-way sensitivity analysis (OWSA) were used.ResultsIn the base-case analysis, pembrolizumab plus chemotherapy resulted in an incremental gain of 0.23 QALYs at an additional cost of $18,199.63, resulting in an ICER of $80,557.23/QALY. …”
Get full text

Honoring the Afro-Colombian musical culture with the naming of Epipedobates currulao sp. nov. (Anura, Dendrobatidae), a frog from the Pacific rainforests by Mileidy Betancourth-Cundar, Juan Camilo Ríos-Orjuela, Andrew J. Crawford, David C. Cannatella, Rebecca D. Tarvin

“…., blotches that are either more white than yellow or absent in E. boulengeri. In addition, the advertisement calls are distinct, with E. currulao sp. nov. having a single but long call in each call series while E. boulengeri has 2–6 calls in a series with each call being much shorter in length. …”
Get full text

Prevalence and Risk Factors for Opioid-Induced Constipation in an Older National Veteran Cohort by Fern FitzHenry, Svetlana K. Eden, Jason Denton, Hui Cao, Aize Cao, Ruth Reeves, Guanhua Chen, Glenn Gobbel, Nancy Wells, Michael E. Matheny

“…OIC was identified through additions/changes in laxative prescriptions, all-cause constipation identification through diagnosis, or constipation related procedures in the presence of opioid exposure. …”
Get full text

Air Quality of Bursa: Temporal and Spatial Evaluation of PM10, PM2.5, NO2 and SO2 Pollutants Using IDW Geostatistical Technique by Duygu Arıkan İspir, Ferruh Yıldız

“…Human health is negatively impacted by this issue in addition to the environment. In this study, spatial and temporal analysis of particulate matter 10 (PM10), particulate matter 2.5 (PM2.5), sulfur dioxide (SO2) and nitrogen dioxide (NO2) pollutants for 2022 was conducted within the provincial borders of Bursa, Turkey. …”
Get full text

RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling by Megan A. Palmer, Rebecca Kirchhoff, Claudia Buerger, Yvonne Benatzy, Nils Helge Schebb, Bernhard Brüne

“…Using a cytokine cocktail containing IL-17A, interferon-gamma and tumour necrosis factor-alpha to produce a psoriasis-like phenotype, a role for ALOX15B in human epidermal keratinocyte inflammation was investigated. siRNA-mediated silencing of ALOX15B increased CCL2 expression and secretion. In addition to CCL2, secretion of CCL5 and CXCL10 were elevated in skin equivalents treated with lipoxygenase inhibitor ML351. …”
Get full text

Reproductive and persistence strategy of the liverwort Arnellia fennica after the last glaciation in the area of disjunction in Central Europe (Polish Tatra Mountains, carpathians) by Piotr Górski, Monika Szczecińska, Jakub Sawicki

“…These studies address the following questions: (1) why A. fennica, an arctic-alpine species, has only been found at low elevations in the Tatra Mountains so far, (2) what were the possibilities of its survival during the glaciation period as verified based on the latest paleoglaciological map, (3) how this species persists in the Tatras and why it remains a rare plant. As a result, nine additional new occurrences were found, bringing the total to 13 throughout the massif. …”
Get full text

INFORMACINIS GENOMAS, INDIVIDO IR POPULIACIJOS GENOMAI by Jonas Rubikas

“…Information genome increases by addition of new information necessary for individual and population under impact of selection. …”
Get full text

Protective effects of apigenin in neurodegeneration: An update on the potential mechanisms by Ali Mohammadkhanizadeh, Mohammad Sheibani, Soroush Taherkhani, Davood Nourabadi, Seyed Mahdi Mohamadi-Zarch, Farnaz Nikbakht, Yaser Azizi

“…Oxidative stress, resulting from an imbalance between the production of reactive oxygen species (ROS) and the body's antioxidant defenses, is a hallmark of neurodegenerative diseases. …”
Get full text

Multiscale Composites: Assessment of a Feasible Manufacturing Process by R. Volponi, P. Spena, F. De Nicola, L. Guadagno

“…Unfortunately, the loading of more than 0.3-0.5% of CNT can lead to high resin viscosities that are unacceptable for such kind of processes. In addition to the viscosity issues that are related to the high CNT content, a filtration effect of the nanofillers caused by the fibrous medium may also lead to inadequate final component quality. …”
Get full text

A scoping review of HIV epidemiologic, sociocultural and programmatic studies related to transgender women and men who have sex with men in Cambodia, 1999-2019. by Jan W de Lind van Wijngaarden, Frits van Griensven, Ly Penh Sun, Stephen Wignall

“…From each of the returned citations we subsequently studied reference lists to find additional data sources. We also searched websites for reports commissioned by national and international governmental and non-governmental organizations.…”
Get full text