Ameliorative Effect of Hovenia dulcis Fruit Pedicel Polysaccharides on Alcohol-Induced Intestinal Injury in Mice Investigated Using 16S rRNA Sequencing and Metabolomics by ZHANG Yuchao, ZHU Sijie, LIU Liangyu, WANG Jianyun, ZHANG Jiaxin, SU Zexiong, CHEN Jiangyan, LIU Xudong

“…Using high-throughput 16S rRNA gene sequencing technology and metabolomics, we investigated the impacts of HDPs on the gut microbiota and metabolic profile of mice with alcohol-induced intestinal injury. Additionally, enzyme-linked immunosorbent assay (ELISA), immunohistochemistry, real-time quantitative polymerase chain reaction (qPCR), and Western blot were employed to detect the changes in the expression of intestinal inflammatory factors, tight junction proteins, bile acid metabolism-related genes and proteins. …”
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GS-DTA: integrating graph and sequence models for predicting drug-target binding affinity by Junwei Luo, Ziguang Zhu, Zhenhan Xu, Chuanle Xiao, Jingjing Wei, Jiquan Shen

“…In particular, when considering important nodes and complex substructures in molecules, they may not be able to fully explore the potential relationships between different parts. In addition, when dealing with protein structures, some methods ignore the connections between amino acid fragments that are far apart in sequence but may work synergistically in function. …”
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Customer Loyalty Based on Service Quality, Banking Image, and Fairness Mediating Role of Customer Satisfaction by Abdul Fatah Rusydi, Muhtadi Ridwan, Vivin Maharani Ekowati, Achmad Sani Supriyanto, Fuadah Binti Johari

“…Likewise, the Maqashid Syari'ah Index (MSI) fairness concept can have a direct impact on consumer loyalty. In addition, the study's findings suggest that customer happiness can mediate the impact of service quality, image, and fairness on customer loyalty. …”
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Diagnosis and treatment of arterial stiffness, pulmonary hypertension, diastolic cardiac dysfunction against the background of ischaemic heart disease in comorbid patients by Nadezhda N. Pribylova, Kristina O. Leonidova, Vladislav S. Pribylov, Evgeny A. Shabanov, Sergey A. Pribylov, Nikita V. Novikov

“…The study found that the addition of the combined antihypertensive drug amlodipine-perindopril to standard therapy contributed to normalization of AS, PH and BP during three months of treatment. …”
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Diagnostic role of circulating long non-coding RNA LINC00312 in patients with non-small cell lung cancer: a retrospective study by Ruoqian Zhang, Yan Jiang, Jing Gu, Xilin Zhang, Yanping Xie

“…Results Here, we revealed that LINC00312 was lowly expressed in NSCLC and low LINC00312 expression manifested a poor prognosis. Additionally, compared with the healthy volunteer group, a reduction of circulating LINC00312 in patients with NSCLC was observed in both the training and validation groups. …”
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A Quality Improvement Project Aimed at Reducing Patient Falls in Ambulatory Clinics by Patricia Macolino, Katie Fox, Rebecca Fitzpatrick, Vivek N. Ahya, Ilona Lorincz, Barbara Prior

“… # Conclusion While the initial intervention was only moderately successful, it led to a renewed focus on the risk of patient falls, which resulted in additional interventions and ultimately a reduction in high harm falls and the annual falls rate…”
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Immobilization of purified pectinase from Aspergillus nidulans on chitosan and alginate beads for biotechnological applications by Hamed M. El-Shora, Sabah A. Abo-Elmaaty, Gharieb S. El-Sayyad, Widad M. Al-Bishri, Ahmed I. El-Batal, Mervat G. Hassan

“…In addition, the Z values were 44.6 and 31.54 °C, while the D values were 79.2 and 95.1 min. …”
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Immunotherapy in Recurrent Ovarian Cancer by Keyao Chen, Jingjing Wang, Meng Yang, Shaoqiong Deng, Li Sun

“…Methods: We systematically reviewed recent immunotherapy advances for recurrent ovarian cancer, including the efficacy and mechanisms of single and dual immune checkpoint inhibitors, checkpoint inhibitor combinations with chemotherapy or radiotherapy, anti-angiogenic agents, PARP inhibitors, antibody–drug conjugates (ADC), tumor vaccines, and adoptive cell therapies (ACT). Additionally, we assessed emerging research on biomarkers predictive of immunotherapy responsiveness in ovarian cancer. …”
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Evaluation of the role of hydroxychloroquine as a lipid profile improving and glucose adjusting drug in Egyptian females with inactive rheumatoid arthritis by Aliaa O. El-Hady, Mai M. Kamel, Yasmin T. Mosaad, Maha A. Ali, Soad S. El Molla

“…Conclusion HCQ significantly improved the blood glucose level in patients with inactive RA, in addition to the serum levels of TC, TG, HDL-Cholesterol, LDL-Cholesterol and arthrogenic index. …”
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Sustainability metrics targeted optimization and electric discharge process modelling by neural networks by Muhammad Sana, Muhammad Asad, Muhammad Umar Farooq, Mehdi Tlija, Rodolfo Haber

“…EDM is often criticized due to its low machining rates, therefore, in the current work,  cryogenic treatment (CT) has been performed on the brass electrode to evaluate the improvement in the machining rates. In addition, kerosene oil (KO) has been engaged in traditional EDM which is replaced with the deionized water (DI) based dielectric as a sustainable alternative. …”
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Prevalence, Infectivity, and Associated Risk Factors of Hepatitis B Virus among Pregnant Women in Yirgalem Hospital, Ethiopia: Implication of Screening to Control Mother-to-Child T... by Anteneh Amsalu, Getachew Ferede, Setegn Eshetie, Agete Tadewos, Demissie Assegu

“…A total of 475 pregnant women were recruited, and data on sociodemography and potential risk factors were collected using a structured questionnaire. In addition, blood samples were tested for HBsAg, and HBsAg positive samples were retested for HBeAg using commercially available strip test. …”
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Fundamentals for forage crop breeding and seed production in Russia by V. M. Kosolapov, V. I. Cherniavskih, S. I. Kostenko

“…However, the destroyed system of elite and commercial seed production does not allow these varieties to take their rightful place in fodder production, and the market still possesses a large share of non-varietal and mass scale reproduction seeds. In addition, imported seeds brought to the Russian market are often disguised as lawn varieties to reduce the cost and simplify their entry to the market. …”
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Lysine requirement of weaned piglets by S. Goethals, P. Bikker, J.H.M. Rijpert, B. Ampe, J.W. Spek, S. Millet

“…Linear, quadratic and linear-plateau models were used to gain insight into the effect of SID lysine addition on average daily gain and feed efficiency for the combined dataset and separately for the individual experiments. …”
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Effective interventions to prevent youth vaping behaviours: a rapid review by Ana Paula Belon, Laura Nieuwendyk, Tasha Allen, Melissa Worrell, Candace I J Nykiforuk

“…We applied PROGRESS-Plus (Place of residence, Race/ethnicity/culture/language, Occupation,Gender/sex, Religion, Education, Socioeconomic status, Social capital, and additional context-specific factors) for an equity analysis. …”
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Upregulated miR-206 Aggravates Deep Vein Thrombosis by Regulating GJA1-Mediated Autophagy of Endothelial Progenitor Cells by Yan Li, Jingping Ge, Yuanyuan Yin, Ruowen Yang, Jie Kong, Jianping Gu

“…Furthermore, silencing of miR-206 suppressed the autophagy of EPCs via upregulating GJA1. miR-206 knockdown repressed thrombus formation, enhanced the homing ability of EPCs to the thrombosis site, and facilitated thrombus resolution in DVT mouse models. Additionally, miR-206 was upregulated while GJA1 was downregulated in vascular tissues of DVT mice. miR-206 knockdown elevated GJA1 expression in vascular tissues of DVT mice. …”
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Effect of Cooking Oil on the Fatty Acid Profile of Beef Sausage Fortified with Edible Deboned Meat Waste by Babatunde O. Alao, Andrew B. Falowo, Elizabeth Bosede Aladejana

“…The proximate analysis results revealed significant differences (P<0.05) in fat, fat free dry matter (FFDM), and moisture contents across the treatment. …”
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Predicting loss of independence among geriatric patients following gastrointestinal surgery by Michaela R. Cunningham, Christopher L. Cramer, Ruyun Jin, Florence E. Turrentine, Victor M. Zaydfudim

“…The applicability of this scoring tool to additional surgical sub-specialties and external validation should be explored in future studies.…”
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Molecular Mechanism During Mycelium Subculture Degeneration of <i>Volvariella volvacea</i> by Lidan Feng, Lujuan Wang, Yuanxi Lei, Jie Li, Fengyun Zhao

“…The results showed that as the number of subcultures increased, the diameter of the mycelium and biological efficiency gradually decreased; in addition, the time in which the primordium formed increased and the production cycle was lengthened, while strains M4 and M5 lacked the ability to produce fruiting bodies. …”
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Exposure to specific polyfluoroalkyl chemicals is associated with cardiovascular disease in US adults: a population-based study by Wenwen Xiao, Guojin Jian, Fei Ma, Hong Li, Xiaohong Yang, Hengyang Zhang, Yongping Cao

“…Logistic regression models were employed to assess the association between single PFC and CVD. Generalized additive model (GAM) was used for evaluating nonlinear relationships. …”
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Injury mortality in South Africa: a 2009 and 2017 comparison to track progress to meeting sustainable development goal targets by Megan Prinsloo, Shibe Mhlongo, Rifqah A. Roomaney, Lea Marineau, Thakadu A. Mamashela, Bianca Dekel, Debbie Bradshaw, Lorna J. Martin, Carl Lombard, Rachel Jewkes, Naeemah Abrahams, Richard Matzopoulos

“…Post-mortem files for non-natural deaths were reviewed, with additional data from the Western Cape. Age-standardised rates, 95% confidence intervals (CIs), and incidence rate ratios (IRRs) were calculated for manner of death rate comparisons and for age groups. …”
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