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60621
Does climate-smart agriculture technology improve farmers' subjective well-being? Micro-level evidence from Odisha, India
Published 2025-01-01“…Low utilization of technology may not yield benefits for farmers, while the adoption of advanced technology may not be economically viable. Additionally, CSAT is not easily available to households residing in low-lying areas, preventing them from improving their well-being. …”
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60622
Augmented virtuality technology in education: taxonomy of augmented virtuality types
Published 2024-12-01“…Various approaches to the augmented virtuality implementation by its addition with real objects are identified. Methodology. …”
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60623
A multi-strain human skin microbiome model provides a testbed for disease modeling
Published 2025-02-01“…A remarkable feature of this model is the persistence of Cutibacterium acnes in an aerobic tissue culture environment, since C. acnes growth is typically demonstrated under anaerobic conditions, suggesting that the skin tissue model is conducive to more natural growth states of native skin strains. The addition of cytokines representative of atopic dermatitis elicited a marked decrease in tissue barrier by day 7 compared to healthy controls, irrespective of the microbiome presence. …”
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60624
The efficacy of chelated micronutrient fertilisers in tomato cultivation
Published 2024-12-01“…The practical significance of this study lies in identifying the effects of foliar fertilisation on tomato yield in protected soil conditions. Additionally, the study established optimal and scientifically justified rates and application timings for complex fertilisers with chelated micronutrients. …”
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60625
Psychotropic Drugs in Dermatology Part 1: Anti-depressants and Mood Stabilisers
Published 2025-01-01“…These include selective serotonin reuptake inhibitors like citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, and sertraline, alongside selective serotonin norepinephrine reuptake inhibitors such as venlafaxine, desvenlafaxine, and duloxetine. Additionally, norepinephrine dopamine reuptake inhibitors like bupropion; tricyclic antidepressants including doxepin, amitriptyline, imipramine, and clomipramine; and tetracyclic antidepressants like mirtazapine are commonly employed. …”
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60626
Review of experience in the construction of NPP using modular structures with external sheet reinforcement
Published 2024-10-01“…However, based on the results of analyzing the experience of implementation of AR-1000 and SAR-1000 design solutions, it was found that additional logistical risks and risks of ensuring the quality of monolithic concrete placement arise when implementing this technology.…”
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60627
Quantum chemical study of molecular properties of small branched-chain amino acids in water
Published 2025-01-01“…Calculated molecular descriptors involve dipole moment, quadrupole moment, dipole polarizability, energy of zero-point vibration and total entropic term which enter the standard Gibbs energy. In addition, a set of collective electronic and thermodynamic properties associated with redox process were evaluated: ionization energy, electron affinity, chemical hardness, molecular electronegativity, electrophilicity index, absolute oxidation and reduction potentials. …”
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60628
NT5E (CD73) as a prognostic biomarker and therapeutic target associated with immune infiltration in lung adenocarcinoma
Published 2025-02-01“…A strong positive correlation was observed between NT5E expression and the presence of immune cells, including dendritic cells, macrophages, and CD4+ T cells, as well as the expression of various immune cell markers, suggesting that NT5E may influence the prognosis of LUAD patients by regulating immune cell infiltration. Additionally, drug sensitivity analysis highlights the potential of selumetinib and PD318088, both MEK1/2 inhibitors, to target NT5E in LUAD treatment, suggesting their use as single agents or in combination with other therapies. …”
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60629
In silico methods for immunogenicity risk assessment and human homology screening for therapeutic antibodies
Published 2024-12-01“…Although this perspective discusses the in-silico immunogenicity risk assessment for monoclonal antibodies, bi-specifics, multi-specifics, and antibody-drug conjugates, the analysis of additional therapeutic modalities such as enzyme replacement proteins, blood factor proteins, CAR-T, gene therapy products, and peptide drugs is also made available on the ISPRI platform.…”
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60630
Dissecting macrophage heterogeneity and kaempferol in lung adenocarcinoma: a single-cell transcriptomic approach and network pharmacology
Published 2025-01-01“…Tumor-associated macrophages (TAMs) within the TME promote tumorigenesis and evasion of immune surveillance, though their heterogeneity poses challenges in understanding their roles and therapeutic targeting. Additionally, traditional Chinese medicine (TCM) offers potential anti-cancer agents that could modulate the immune landscape. …”
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60631
The Examination of Self-Efficacy Beliefs of Physical Education Pre-Service Teachers According to Different Variables
Published 2018-12-01“…Developed by the researchers, this form includes questions aiming to obtain the following information about the participants: age, gender, the university they attend, class level, family income level, and educational background of parents. In addition, the study used “Teacher Self-efficacy Scale”, which was developed by Tschannen-Moran and Woolfolk Hoy (21) and adapted to Turkish context by Çapa et al. (7). …”
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60632
The effect of β-carotene supplementation above requirement on the production and reproduction performance of female sheep and goats - A mini review
Published 2024-05-01“…However, the supplementation of β-carotene above the requirements seems to not affect the production and reproduction parameters such as body weight, milk production, estrus parameters, conception rate, pregnancy rate, and litter size. …”
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60633
YTHDF1 Regulates RELA m6A Modification and Activates the NF‐Kappa B Signaling Pathway to Promote the Mechanism of Gastric Cancer
Published 2025-01-01“…YTHDF1 inhibits apoptosis while promoting the migration and proliferation of GC. Additionally, it stimulates the NF‐κB pathway and controls the translation of RELA.…”
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60634
Microbial communities in the phyllosphere and endosphere of Norway spruce under attack by Heterobasidion
Published 2025-01-01“…The primary purpose was to uncover signature characteristic microbiome harbored by asymptomatic trees compared to diseased trees. Additionally, the study was to explore the inter-kingdom and intra-kingdom interactions in microbiome (bacteria and fungi) of symptomatic versus asymptomatic trees. …”
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60635
Research on the Relationship between Dynamic Message Sign Control Strategies and Driving Safety in Freeway Work Zones
Published 2018-01-01“…The first occurrence of a decision sign that contains lane change content is key to the driver’s decision; in addition, the position of signage with such information should gradually be moved closer to work zones with increasing traffic flow.…”
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60636
META-ANALYSIS: SQUAMOUS CELL CARCINOMA CASES ARISING FROM MORBUS HANSEN IN DR. SITANALA CENTRAL HOSPITAL (2011-2021)
Published 2023-06-01“…Most patients had Morbus Hansen type BL (borderline lepromatous) and had been living with the condition for an average of 23 years. Additionally, a significant number of patients had a normal body mass index (52%) within the range of 20-24.9. …”
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60637
Is preoperative imaging of sentinel lymph node in breast cancer necessary? A retrospective case control study
Published 2025-02-01“…Lymphoscintigraphy detected SLN in 407 of 428 (95.09 %) patients in group 2. Due to the additional SLN imaging in group 2, the time between radiotracer injection and start of surgery was significantly prolonged (p < 0.001). …”
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60638
IHSCR: Energy-efficient clustering and routing for wireless sensor networks based on harmony search algorithm
Published 2017-11-01“…Then, a new energy-efficient clustering algorithm is designed based on several improvements made to harmony search algorithm: (1) a discrete encoding scheme of a harmony for clustering is proposed; (2) a roulette wheel selection method is designed to choose a gateway for a regular sensor node to join, which is employed by two steps (i.e. initialization of harmony and improvisation of a new harmony); (3) the dynamically changed harmony memory considering rate is designed for improvisation of a new harmony; (4) a local search scheme is proposed to improve the best harmony within the harmony memory in iterations. In addition, the improved harmony search based energy-efficient routing algorithm that we proposed previously is employed to balance the energy consumption of gateways in the routing phase. …”
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60639
Appropriate Blood Pressure in Cerebral Aneurysm Clipping for Prevention of Delayed Ischemic Neurologic Deficits
Published 2020-01-01“…To prevent DNID, we recommend that optimal blood pressure should not be lower than 95 for SBP, 50 for DBP, and 61.7 mmHg for MAP. Additionally, we suggest that Δ SBP, Δ DBP, and Δ MAP should be less than 36, 27, and 32 mmHg, respectively.…”
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60640
Intranasal Immunization with DNA Vaccine HA-CCL19/Polyethylenimine/Chitosan Composite Provides Immune Protection Against H7N9 Infection
Published 2024-12-01“…Results: Our results revealed that the CCL19 molecular adjuvant exerts a substantial immunomodulatory enhancement effect on the H7N9-HA DNA vaccine, inducing more pronounced cellular and humoral immunity. Additionally, our results indicated that the composite formed by the HA-CCL19 DNA in combination with PEI and CS effectively activates local mucosal immunity as well as systemic humoral and cellular immunity, offering 100% protection against lethal doses of homologous virus challenges. …”
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