Screening Selected Solanum Plants as Potential Rootstocks for the Management of Root-Knot Nematodes (Meloidogyne incognita) by Benjamin A. Okorley, Charles Agyeman, Naalamle Amissah, Seloame T. Nyaku

“…They advance a complex parasitic relationship with roots of tomato plants leading to modification of host structural and physiological functions in addition to significant yield loss. Resistance in solanaceous plants to RKNs has been identified and associated with the possession of Mi gene. …”
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Inline Mapping of Amorphous Silicon Layer Thickness of Heterojunction Precursors Using Multispectral Imaging by Saravana Kumar, Christian Diestel, Saed Al-Hajjawi, Jurriaan Schmitz, Marc Hemsendorf, Jonas Haunschild, Stefan J. Rupitsch, Stefan Rein

“…The study demonstrates that quantitative inspection of ultra-thin amorphous silicon (a-Si) layers on textured silicon substrates requires an extension of the standard RGB illumination by two additional LED wavelengths in the near-UV. As the required five images are measured in less than a second, the tool is a suitable candidate for inline applications. …”
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Primary Study on Effect of Extraction Methods on the Properties and Activities of Polysaccharides from <i>Geum japonicum var. Chinense F. Bolle</i> by Xuan Chen, Ying-Bo Liu, Yong Deng, Jian-Yong Zhang

“…In particular, DESE and PLE showed the best homogeneity with distinct molecular weights of 39.5 kDa and 17.6 kDa, respectively. In addition, biological evaluation indicated that DESE and MAE exhibited relatively stronger antioxidant activities as evidenced by DPPH and ABTS assays. …”
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Hypericin mediated photodynamic therapy induces ferroptosis via inhibiting the AKT/mTORC1/GPX4 axis in cholangiocarcinoma by Wei An, Kai Zhang, Guangbing Li, Shunzhen Zheng, Yukun Cao, Jun Liu

“…In terms of molecular mechanism, we found that HY-PDT induced ferroptosis by decreasing GPX4 expression via suppression of the AKT/mTORC1 signaling pathway. In addition, we also found that HY-PDT inhibit cholangiocarcinoma cells migration and the EMT process by inhibiting the AKT/mTORC1 pathway. …”
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A Cost-Effective and Robust Cell-Based Bioassay Method for Evaluating the Bioactivity of Trastuzumab-like Antibodies by Pooja Bharali, Subhash Chand, Harish Chander

“…The biological activity of trastuzumab was determined using the inhibition of proliferation (IOP) assay on the SKBR3, which was optimized based on the parameters of cell seeding density, drug dilution range, and incubation time, and it was further validated as per the compendial guidelines and found valid for the parameters of specificity, accuracy (% relative bias = 0.0067%), precision (repeatability: % GCV = 1.21%), linearity (R2 = 0.99), and range (50% to 200%). Additionally, the biological activity of different trastuzumab biosimilars was assessed using the validated IOP assay and compared to the HER2 binding assay performed by flow cytometry. …”
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Lifting COVID-19-associated non-pharmaceutical interventions: potential impact on notifications of infectious diseases transmitted from person to person in 2022 in Bavaria, Germany by Judith Hausmann, Judith Hausmann, Judith Hausmann, Achim Dörre, Katharina Katz, Sarah van de Berg

“…The full impact of NPIs and their discontinuation may only become clear with continued monitoring and assessment of potential additional contributing factors.…”
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Fuzzy Random Characterization of Pore Structure in Frozen Sandstone: Applying Improved Niche Genetic Algorithm by Yao Ya-feng, Lin Jian, Ge Jian, Peng Shi-long, Yin Jian-chao, Ouyang Li-na

“…Compared with the previous least square fitting method, it provides a more accurate approach in characterizing complicated pore structures in frozen rock and soil masses. In addition, the improved niche genetic algorithm effectively overcomes the shortcomings of the traditional genetic algorithm, such as low effectiveness, slow convergence, and weak controllability, which provides an effective way for parameter inversion in the section of frozen geotechnical engineering. …”
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Effect of epicanthoplasty on the descent of the eyebrow by Yong-Il Shin, Kyoung-Jin Kang, Jae-Ran Hong, Montri Khammoonta, Phoebe Kar Wai Lam, Sang-Yoon Lee

“…Background: Epicanthoplasty is an additional surgical technique for blepharoplasty, often performed in conjunction with ptosis correction surgery or eyelid crease surgery, rather than as a standalone procedure. …”
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Accurate Needle Localization in the Image Frames of Ultrasound Videos by Mohammad I. Daoud, Samira Khraiwesh, Rami Alazrai, Mostafa Z. Ali, Adnan Zayadeen, Sahar Qaadan, Rafiq Ibrahim Alhaddad

“…The angular, axis, and tip errors computed for the <i>ex vivo</i> ultrasound videos are within the ranges of 0.3–0.7°, 0.2–0.7 mm, and 0.4–0.8 mm, respectively. Additionally, the angular, axis, and tip errors computed for the <i>in vivo</i> ultrasound videos are within the ranges of 0.2–1.0°, 0.3–1.0 mm, and 0.3–1.1 mm, respectively. …”
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Artificial intelligence empowered voice generation for amyotrophic lateral sclerosis patients by Stefano Regondi, Giordana Donvito, Emanuele Frontoni, Milutin Kostovic, Fabio Minazzi, Sébastien Bratières, Massimiliano Filosto, Raffaele Pugliese

“…Despite the increasing interest in VB, there’s a lack of clear strategies for its effective implementation in rapidly progressing diseases like ALS. Additionally, the perceptual quality of VB on patients with preserved speech, especially when offered early in the disease, remains poorly understood. …”
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Development of a GIS-based register of biogas plant sites in Lower Saxony, Germany: a foundation for identifying P2G potential by Mareike Plinke, Jonas Berndmeyer, Jochen Hack

“…Spatial data on existing biogas plants in Lower Saxony were selected from the Digital Landscape Model (DLM) data, with additional information coming inter alia from the Marktstammdatenregister, the Germany-wide core energy market data register. …”
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QAR Data Imputation Using Generative Adversarial Network with Self-Attention Mechanism by Jingqi Zhao, Chuitian Rong, Xin Dang, Huabo Sun

“…The improved gated recurrent unit is then introduced as the neural unit of GAN, which can successfully capture the temporal relationships in QAR data. In addition, we modify the basic structure of GAN by using an autoencoder as the generator and a recurrent neural network as the discriminator. …”
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Extreme-phenotype genome-wide association study (XP-GWAS) of powdery mildew race 2 W tolerance in the USDA Citrullus germplasm collection by Sandra E. Branham, Venkata Rao Ganaparthi, W. Patrick Wechter, Younghoon Park, Todd Wehner, Angela Davis, Antonia Tetteh, Laura Massey, Sue Hammar, Rebecca Grumet, Shaker Kousik, Amnon Levi

“…Two adjacent SNPs on chromosome 7 were significantly associated with P. xanthii race 2 W tolerance in the bulks and two additional SNPs had a strong signal in the XP-GWAS analysis. …”
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Transcriptomic and Functional Landscape of Adult Human Spinal Cord NSPCs Compared to iPSC-Derived Neural Progenitor Cells by Sasi Kumar Jagadeesan, Ahmad Galuta, Ryan Vimukthi Sandarage, Eve Chung Tsai

“…Functional assays corroborated the transcriptomic findings, demonstrating superior neurogenic potential in iPSC-Br NSPCs. Additionally, we assessed donor-specific influences on NSPC behavior by analyzing gene expression and differentiation outcomes across syngeneic populations from multiple individuals. …”
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Rational metabolic engineering of <i>Corynebacterium glutamicum</i> to create a producer of L-valine by M. E. Sheremetieva, K. E. Anufriev, T. M. Khlebodarova, N. A. Kolchanov, A. S. Yanenko

“…L-Valine is used in the food and pharmaceutical industries, medicine and cosmetics, but primarily as an animal feed additive. Adding L-valine to feed, alone or mixed with other essential amino acids, allows for feeds with lower crude protein content, increases the quality and quantity of pig meat and broiler chicken meat, as well as improves reproductive functions of farm animals. …”
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The Anticancer Activity of Lycium barbarum Polysaccharide by Inhibiting Autophagy in Human Skin Squamous Cell Carcinoma Cells In Vitro and In Vivo by Meihua Zeng, Qingtao Kong, Fang Liu, Jun Chen, Hong Sang

“…At the same time, the regulation of Beclin1, LC3II, Bcl-2, and cl-caspase-3 by LBP was effectively reversed by the cotreatment of SP600125. In addition, LBP increased the survival rate of transplanted nude mice, reduced tumor volume and weight, and downregulated the expression of Ki67 and MMP-2. …”
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Allele-specific PCR with fluorescently labeled probes: criteria for selecting primers for genotyping by V. A. Devyatkin, A. A. Shklyar, A. Zh. Fursova, Yu. V. Rumyantseva, O. S. Kozhevnikova

“…It makes it possible to distinguish alleles in a genome with high accuracy without additional manipulations with DNA samples or PCR products; hence the popularity of this method in genetic association studies in molecular genetics and medicine. …”
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Life Cycle Assessment of Methanol Production from Municipal Solid Waste: Environmental Comparison with Landfilling and Incineration by Cristiano Queiroz Cerqueira, Electo Eduardo Silva Lora, Lidiane La Picirelli de Souza, Márcio Montagnana Vicente Leme, Regina Mambeli Barros, Osvaldo José Venturini

“…The results reveal that methanol production from MSW significantly reduces global warming potential (GWP) by 87% compared to landfilling and 56% compared to incineration. Additionally, the process demonstrates high energy efficiency in electricity generation, achieving 80% of the output of incineration. …”
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0.5 V Digitally-Tunable Filters for Biomedical Applications Exploiting Segmented Duty-Cycled Resistors by Alessandro Fava, Francesco Centurelli, Giuseppe Scotti

“…In this paper, we present the design and the experimental validation of a biquad filter for biomedical applications that takes advantage of segmented duty-cycled resistors to allow for digital tuning over a wide range of the cutoff frequency (<inline-formula> <tex-math notation="LaTeX">$f_{0}$ </tex-math></inline-formula>), quality factor (Q), and gain (K). Additionally, we report on the experimental findings for an 8th-order band pass filter that was created to extract the epilepsy biomarker, related to the fast ripple band (250 Hz&#x2013;500 Hz). …”
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Endoplasmic reticulum stress-related super enhancer promotes epithelial-mesenchymal transformation in hepatocellular carcinoma through CREB5 mediated activation of TNC by Anqi Wang, Sitong Yan, Jiatao Liu, Xiang Chen, Mengyao Hu, Xiao Du, Weijia Jiang, Zhipeng Pan, Lulu Fan, Guoping Sun

“…Analyses of TCGA datasets and tissue arrays showed that CREB5 mRNA and protein expression levels were higher in liver cancer tissues than in paired normal tissues. In addition, overexpression of CREB5 was associated with poor prognosis and an aggressive phenotype in patients with HCC. …”
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