Regulation of ER stress-induced apoptotic and inflammatory responses via YAP/TAZ-mediated control of the TRAIL-R2/DR5 signaling pathway by Y. El Yousfi, F. J. Fernández-Farrán, F. J. Oliver, A. López-Rivas, R. Yerbes

“…On the other hand, it inhibits cFLIP down-regulation in tumor cells experiencing ER stress. In addition, YAP/TAZ controls the expression of pro-inflammatory interleukin-8 (IL-8/CXCL8) in tumor cells undergoing ER stress by a TRAIL-R2/DR5/caspase-8-dependent mechanism. …”
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Prediction of the SYM‐H Index Using a Bayesian Deep Learning Method With Uncertainty Quantification by Yasser Abduallah, Khalid A. Alobaid, Jason T. L. Wang, Haimin Wang, Vania K. Jordanova, Vasyl Yurchyshyn, Huseyin Cavus, Ju Jing

“…When predicting the SYM‐H indices (2 hr in advance) in the large storm, SYMHnet achieves an FSS of 0.553 compared to the FSS of 0.087 of the GBM method. In addition, SYMHnet can provide results for both data and model uncertainty quantification, whereas the related methods cannot.…”
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A low pre-existing anti-NS1 humoral immunity to DENV is associated with microcephaly development after gestational ZIKV exposure. by Sebastián Castro-Trujillo, William R Mejía, Katherine Segura, Juanita Castro-Meneses, Rocío Vega, Doris Salgado, Carlos E Fonseca, Ángela M Ortiz, Federico Perdomo-Celis, Irene Bosch, Carlos F Narváez

“…However, the role of ZIKV NS1-specific humoral immunity in mothers and children with prenatal ZIKV exposure and CZS remains undefined. In addition, considering that most of the at-risk population lives in dengue virus (DENV)-endemic areas, it is not clear what is the association between pre-existing DENV NS1-specific humoral immunity and CZS.…”
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Does sociality affect evolutionary speed? by Socias-Martínez, Lluís, Peckre, Louise Rachel

“…Social selection strength and Ne consequences need to be assessed using 4) as many axes of social variation as possible and 5) in both sexes. 6) Considering the evolutionary covariances in communicative systems might improve the validity of tests for the current framework. In addition, we develop predictions for how variation in each social dimension and component might affect evolutionary speed. …”
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Taenia crassiceps-Excreted/Secreted Products Induce a Defined MicroRNA Profile that Modulates Inflammatory Properties of Macrophages by Diana Martínez-Saucedo, Juan de Dios Ruíz-Rosado, César Terrazas, Blanca E. Callejas, Abhay R. Satoskar, Santiago Partida-Sánchez, Luis I. Terrazas

“…To further define the anti-inflammatory effect of TcES in the response of LPS-stimulated macrophages, we performed transcriptomic array analyses of mRNA and microRNA to evaluate their levels. Although the addition of TcES to LPS-stimulated BMDM induced modest changes in the inflammatory mRNA profile, it induced the production of mRNAs associated with the activation of different receptors, phagocytosis, and M2-like phenotype. …”
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A study on the pharmacovigilance of various SGLT-2 inhibitors by Yanwen Dong, Yangyang Wang, Yangyang Wang, Xiaomei Lan, Xiaomei Lan, Huiyan Zeng, Huiyan Zeng

“…Four signal detection metrics—reporting odds ratio (ROR), proportional reporting ratios (PRRs), Bayesian Confidence Propagation Neural Network (BCPNN), and empirical Bayesian geometric mean (EBGM)—were utilized to infer ADRs and assess differences among specific SGLT2i drugs through intersection analysis.ResultsExcept for canagliflozin, both dapagliflozin and empagliflozin showed a general increase in ADRs. …”
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Putative evolution of Myxococcus fulvus 124B02 plasmid pMF1 from a chromosomal segment in another Myxococcus species by Shruti Jain, Gaurav Sharma

“…Here, we first reannotated the pMF1 plasmid genome sequence and identified two additional open reading frames or putative genes which were not annotated until now. …”
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Assessing the Impact of Land Use and Land Cover Change on Environmental Parameters in Khyber Pakhtunkhwa, Pakistan: A Comprehensive Study and Future Projections by Mehjabeen Khan, Ruishan Chen

“…Projections for 2100 predict LST rising to 55.3 °C, with NDVI, MNDWI, and NDMI dropping to 0.36, 0.17, and 0.21, respectively. …”
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Facile synthesis of size-tunable L-carnosine-capped silver nanoparticles and their role in metal ion sensing and catalytic degradation of p-nitrophenol by Akash Kumar, Ridhima Chadha, Abhishek Das, Nandita Maiti, Rayavarapu Raja Gopal

“…The ʟ-car-AgNPs exhibited promising sensing capabilities with limits of detection of 141.79 ppb (1.2 μM) for Cd2+, 131.33 ppb (0.63 μM) for Pb2+, 215.35 ppb (2.8 μM) for As3+, and 245.49 ppb (4.7 μM) for Cr3+. Additionally, these nanoparticles demonstrated catalytic activity regarding the degradation of p-nitrophenol (P-NP), achieving complete degradation of 0.25 and 1 mM solutions within 5 and 10 min, respectively. …”
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Research on damage and degradation of coal-bearing sandstone under freeze-thaw cycles by Yiwen Mao, Ming Li, Peng Wu, Shuai Guo, Fuqiang Zhu

“…The CT scan results show that with the decrease of the freezing temperature and the increase of the number of freeze-thaw cycles, the number and geometric size of pores on the sample cross section increase significantly. Additionally, the evolution equation of freeze-thaw damage factors was established with freezing temperature and number of freeze-thaw cycles as parameters, and the internal mechanism and physical characterization of freeze-thaw damage degradation of coal measure sandstone were revealed. …”
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Pimavanserin Treatment for Parkinson’s Disease Psychosis in Clinical Practice by Khashayar Dashtipour, Fiona Gupta, Robert A. Hauser, Cherian A. Karunapuzha, John C. Morgan

“…Effective treatment of PDP may reduce disturbing symptoms of psychosis, thus improving patient function and quality of life. In addition, effective pharmacotherapy for PDP may also facilitate the use of other medications needed to treat neurological symptoms of PD (e.g., tremor, bradykinesia, and dyskinesia), although they may also have adverse effects that contribute to symptoms of PDP.…”
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A 3D Empirical Model of Electron Density Based on CSES Radio Occultation Measurements by He Huang, Jian Lin, Song Xu, Huijun Le, Feng Guo, Zhima Zeren, Libo Liu, Xuhui Shen

“…The results show that CSES_Ne‐Profile Model precedes the IRI model. Additionally, our model captures the merging phenomenon of the two peaks of equatorial ionospheric anomaly, which is missed by IRI. …”
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Relationship among core competency, self-efficacy and transition shock in Chinese newly graduated nurses: a cross-sectional study by Ting Wang, Shuping Tong, Lan Xu, Yahui Tong, Zhaofang Tang, Lifen Mao, Xiaoqing Shi

“…The core competency and self-efficacy of the newly graduated nurses had a negative impact on the transition shock (β=−0.151, p=0.026; β=−0.379, p<0.001). Additionally, self-efficacy played a mediating role in the relationship between core competency and transition shock, with a mediating effect accounting for 57.34% of the total effect.Conclusions The transition shock of newly graduated nurses was at a moderate level, with the highest level of transition shock occurring within the first year of employment. …”
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That “darned Dorsiceratus case” (Copepoda, Harpacticoida, Cletodidae T. Scott)—an attempt of a systematic approach, including the description of three new species by Kai Horst George, Lukas Tönjes, Songül Yurtdaş

“…In order to obtain a most realistic assessment of this, taxonomic studies are essential in addition to faunistic ones. They reveal that particularly rare deep-sea groups can be characterised by a large number of different species even from the same location. …”
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Innovative applications and future trends of multiparametric PET in the assessment of immunotherapy efficacy by Tingting Qiao, Tingting Qiao, Zhaoping Cheng, Yanhua Duan

“…Review articles and meta-analyses were consulted for additional references but excluded from quantitative analysis. …”
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Estimation of 1 km Dawn–Dusk All-Sky Land Surface Temperature Using a Random Forest-Based Reanalysis and Thermal Infrared Remote Sensing Data Merging (RFRTM) Method by Yaohai Dong, Xiaodong Zhang, Xiuqing Hu, Jian Shang, Feng Zhao

“…However, as only the Moderate Resolution Imaging Spectroradiometer (MODIS) is adopted as the TIR source for merging, current 1 km all-sky LST products are limited to the MODIS observation time. …”
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Oxidative Stress, Lipid Peroxidation, and Loss of Hyaluronic Acid in the Human Vitreous Affected by Synchysis Scintillans by Loredana Bergandi, Oleksii A Skorokhod, Rosalba La Grotta, Evelin Schwarzer, Raffaele Nuzzi

“…The consequently higher lipoperoxide-dependent 4-HNE production in synchysis scintillans was detectable in aqueous and vitreous humors as a significant increased accumulation of 4-HNE-protein conjugates vs nonsynchysis vitreoretinal disorders. Additionally, hyaluronic acid (HA) was significantly decreased in the vitreous body of synchysis scintillans patients. …”
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Revamping field practicum: insights for future health services management professionals by Fatemeh Mohabati, Marzieh Arefi, Seyed Pouria Hedayati

“…To achieve desirable outcomes through a fundamental revision strategy, it was decided that, in addition to students’ presence in hospitals (including the office of senior hospital managers and the quality improvement and accreditation unit), students should also be present in the deputyships and central units of Zabol University of Medical Sciences (treatment, resource development and management, food and drug administration, and the center for management of medical emergencies). …”
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Impact of smart city construction policy on high-quality economic development of coastal cities by Lihong Wang, Lihong Wang, Feng Li, Yang Gao, Kedong Yin

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Macrophage Infiltration and ITGB2 Expression in ESCC: A Novel Correlation by Tao Huang, Longqian Wei, Huafu Zhou, Jun Liu

“…The higher the expression of ITGB2, the more feasible it is to target macrophages. Additionally, we found that evaluating immune therapy responses in ESCC patients through ITGB2 expression is a viable approach. …”
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