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59881
Lactoferrin: a secret weapon in the war against pathogenic bacteria
Published 2024-10-01“…Lf is a multifunctional glycoprotein with immunomodulatory, anticarcinogenic, wound-healing, antioxidant, antimicrobial, and bone regeneration properties, in addition to improving the gut microbiota. Lf limits the growth of microorganisms through the sequestration of iron but can also interact directly with some components of the outer membrane of Gram-negative bacteria or bind to teichoic acids in Gram-positive bacteria, destabilizing the membrane and resulting in lysis. …”
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59882
Magnetic Field Effects on Convective Heat Transfer of Ferrofluid from a Heated Sphere in Porous Media
Published 2025-05-01“…It is thought that the base fluid’s Prandtl number, Pr=6.8733, is constant. In addition, the flow pattern inside the boundary layer region is shown using streamlines and isotherms, and the underlying physics of the flow behavior is then explored. …”
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59883
MDFGNN-SMMA: prediction of potential small molecule-miRNA associations based on multi-source data fusion and graph neural networks
Published 2025-01-01“…Moreover, the experimental results of an independent test set confirmed the model’s generalization capability. Additionally, the efficacy of MDFGNN-SMMA was substantiated through three case studies. …”
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59884
Toward 6G: An Overview of the Next Generation of Intelligent Network Connectivity
Published 2025-01-01“…The key contributions of this work include a detailed exploration of prospective 6G applications and use cases, such as autonomous systems and integrated communication-sensing scenarios. Additionally, it identifies major challenges—such as advanced coding schemes, energy management, and security—and presents a roadmap for future research in these critical areas. …”
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59885
Assessment of Clinical Features in HIV-Infected Patients with Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention in China
Published 2022-01-01“…In PLWH (mean age: 53.6 ± 10.6 years, 95.8% male, and 79.2% on ART), high-density lipoprotein cholesterol was lower than in HIV-negative controls; however, the statin use was more common, the incidence of hypertension was lower, and low-density lipoprotein cholesterol, and the body mass index were significantly lower than in controls. …”
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59886
Enhancing Educational Systems on Creating Job Opportunities by Promoting Knowledge-Based Economy in the Sultanate of Oman
Published 2025-01-01“…The study aims to explore how education can contribute to reinforcing the knowledge economy in Oman by advancing educational systems and creating new jobs, focusing on the challenges and opportunities within the framework of Oman Vision 2040, which seeks to achieve sustainable economic growth. Additionally, the research discusses differences in averages among respondents' educational qualifications, with the highest average recorded for PhD holders at approximately 4.5% that holders of these qualifications are the ones who can be relied upon to convey and disseminate the culture of the knowledge economy among university and college students. …”
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59887
Exploring Clec9a in dendritic cell-based tumor immunotherapy for molecular insights and therapeutic potentials
Published 2025-02-01“…Furthermore, it discusses the role of Clec9a in the induction and functional activation of Clec9a+ cDC1s, with a particular focus on addressing the challenges related to off-target effects and immune tolerance in the development of tumor vaccines. Additionally, this review explores the potential of Clec9a-targeted approaches to enhance the immunogenicity of tumor vaccines and addresses the utilization of Clec9a as a delivery target for specific agonists (such as STING agonists and αGC) to enhance their therapeutic effects. …”
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59888
The effect of court surfaces on physiological responses and game activities of recreational senior tennis players
Published 2024-07-01“…The results show significant differences between the court surfaces: on CC, players exhibited a higher-average heart rate (152.8 ± 20.3 beats per min vs. 143.7 ± 18.5 on HC, p<0.001), longer rally durations (12.4 ± 8.5 sec vs. 8.1 ± 7.8 on HC, p<0.001), and increased total distance covered (3027.9 ± 396 m vs. 2647.6 ± 378 on HC, p<0.001). Additionally, HC induced significantly faster rally speeds compared to CC (0.70 ± 0.25 shots/s vs. 0.59 ± 0.17 on CC, p<0.001). …”
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59889
Novel PITX2 Mutations including a Mutation Causing an Unusual Ophthalmic Phenotype of Axenfeld-Rieger Syndrome
Published 2019-01-01“…The PITX2 gene may be responsible for a significant portion of ARS with additional systemic defects in the Chinese population. …”
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59890
Optimizing Bacterial Protectant Composition to Enhance Baijiu Yeast Survival and Productivity During Spray Drying
Published 2025-01-01Subjects: Get full text
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59891
Spontaneous blinking and brain health in aging: Large-scale evaluation of blink-related oscillations across the lifespan
Published 2025-01-01“…The results showed that BRO responses were present in all age groups, and the associated effects exhibited significant age-related modulations comprising an increase in sensor-level global field power (GFP) and source-level theta and alpha spectral power within the bilateral precuneus. Additionally, the extent of cortical activations also showed an inverted-U relationship with age, consistent with neurocompensation with aging. …”
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59892
Purchase intention of Millennial Muslims toward B2C e-commerce
Published 2025-02-01“…The findings reveal that perceived risk (β: 0.206), perceived quality (β: 0.440), and enduring involvement (β: 0.240) positively affect perceived trust, whereas situational involvement (β: -0.331) has a negative impact. Additionally, enduring involvement (β: 0.659), situational involvement (β: 0.133), and perceived trust (β: 0.103) were found to positively influence purchase intention, while perceived risk (β: -0.093) negatively affects it. …”
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59893
Greenhouse gas emissions (GHGE), water footprint and nitrogen loss associated with food consumption among adults: findings from the updated LEBANese natiONal food consumption surve...
Published 2025-01-01“…Grains and cereals, the most consumed food category, significantly influenced the water footprint and nitrogen loss. Additionally, meat consumption notably drove greenhouse gas emissions. …”
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59894
Knowledge, attitudes, and practices (KAP) of animal health staff and farmers towards brucellosis control in sheep and goat in China: A cross-sectional study.
Published 2025-01-01“…Among animal health staff, the primary factor associated with KAP was province of residence, sex, level of education, and history of family members infection (p < 0.05). Additionally, brucellosis information primarily originated from traditional promotional materials and veterinarians.…”
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59895
Diagnostic performance of artificial intelligence in detection of renal cell carcinoma: a systematic review and meta-analysis
Published 2025-01-01“…Nevertheless, the presence of heterogeneity between studies and the absence of coherence in the results underscore the necessity for the cautious interpretation of these results and additional prospective studies.…”
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59896
A strategy to improve the adsorption capacity of OPs-dye pollutants from the aqueous environment using adsorbents based on 2D transition metal carbides (V2CTx)
Published 2024-12-01“…The obtained results also indicate that in addition to the cationic nature, other factors, such as the linearity of the molecular structures, the charge of the dye molecules, and the molecular mass of the tested pollutants, are effective in the adsorption process. …”
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59897
miR-26a-5p/ADAM17-Mediated Proteolysis of TREM2 Regulates Neuroinflammation in Hypertensive Mice Following Lead Exposure
Published 2025-01-01“…We demonstrated that hypertension exacerbated Pb-induced neuroinflammation in the prefrontal cortex (PFC), hippocampus, and hypothalamus, as evidenced by increased levels of proinflammatory cytokines (IL-6 and TNF-α) and decreased levels of anti-inflammatory cytokines (CD206 and IL-10). Additionally, hypertension enhanced the neuroinflammatory response in microglia, as indicated by similar changes in cytokine expression in an in vitro cell model. …”
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59898
Experimental Study of the Flow Mechanism of Deep Lacustrine Carbonate Reservoirs in the Yingxi Area of the Qaidam Basin
Published 2022-01-01“…The oil phase flow in the core has the characteristics of non-Darcy flow, and the threshold pressure gradient is 0.01–0.003 MPa/m. Additionally, for the oil-water two-phase flow in the fractured core, the water phase relative permeability of the residual oil is high. …”
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59899
Improved Consistency of Lung Nodule Categorization in CT Scans with Heterogeneous Slice Thickness by Deep Learning-Based 3D Super-Resolution
Published 2024-12-01“…Furthermore, thick- and thin-slice CT images had a nodule volume difference of 52.2 percent on average which was reduced to a 15.7 percent difference with DL-generated thin-slice CT. In addition, the proposed method increased the agreement of lung nodule categorization using Lung-RADS by 74 percent. …”
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59900
The relationship between professional autonomy and job performance among Iranian ICU nurses: the mediating effect of job satisfaction and organizational commitment
Published 2025-01-01“…They can improve working conditions by offering competitive salaries, simplifying promotion processes, and involving nurses in decisions related to patient care. Additionally, essential steps to consider are supporting nursing autonomy, organizing educational classes, and implementing strategies such as stress reduction programs, reducing workloads, addressing nursing shortages, and decreasing working hours.…”
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