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59521
Synthesis of Amino Acid Schiff Base Nickel (II) Complexes as Potential Anticancer Drugs In Vitro
Published 2020-01-01“…Complex 2 can cause cell cycle arrest in the G2/M phase. Additionally, complex 2 can regulate the Bcl-2 family and autophagy-related proteins.…”
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59522
Sex-based variations in breath-holding: oxygen storage and diving response among non-divers
Published 2025-01-01“…We conducted a study comparing the maximum breath-hold duration, heart rate (HR) reduction, peripheral oxygen saturation (SpO2), and spleen volume and contraction in 37 men and 44 women, all of whom had no prior breath-holding experience. They performed two dry apneas separated by 2 min; the first was limited to 60 s, followed by a maximal effort apnea. …”
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59523
Study of Association of Vitamin D Receptor Gene Polymorphisms with Diabetic Nephropathy
Published 2024-04-01“…Conclusion: This study did not find a significant association of VDR SNPs (TaqI, BsmI, and ApaI) with T2DN. …”
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59524
Investigating the Relationship of Inflammatory Cytokines and Brain-Derived Neurotrophic Factor with Cognitive Functions in Multiple Sclerosis Patients
Published 2024-12-01“…The patients were 55 women and 13 men. Additionally, the control group consisted of 22 healthy individuals (17 women and 5 men) who were matched based on their age, gender, and educational background. …”
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59525
Active versus sham transcranial direct current stimulation (tDCS) as an adjunct to varenicline treatment for smoking cessation: Study protocol for a double-blind single dummy rando...
Published 2022-01-01“…Therefore, it is important to develop new and more effective treatment approaches that can improve and maintain long-term abstinence, in order to decrease the prevalence of tobacco-related deaths and disease. Furthermore, the addition of longitudinal neuroimaging can shed light on neural circuitry changes that might occur as a result of brain stimulation, furthering our understanding of tDCS in addiction treatment.…”
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59526
Differentially localizing isoforms of the migraine component calcitonin gene-related peptide (CGRP), in the mouse trigeminal ganglion: βCGRP is translated but, unlike αCGRP, not so...
Published 2025-01-01“…Furthermore, similar IHCs were produced in KO animals after being treated with monoclonal CGRP antibodies to study the origin of the observed CGRP. Additional IHCs were conducted in KO and WT mice to locate CGRP sorting peptides within neuronal cell bodies. …”
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59527
In silico analysis of SNPs and miRNAs of KCTD13, CSDE1, SLC6A1 genes associated with autism spectrum disorder
Published 2025-01-01“…The findings suggest that computational analysis of miRNA and SNPs on these ASD-related genes could provide valuable insights into the genetic mechanisms underlying ASD. In addition, it is suggested to investigate through experimental research whether the findings can be utilized as potential biomarkers for diagnosing and treating autism.…”
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59528
Three Inferior Oblique Weakening Procedures for Management of Mild Hypertropia in Unilateral Superior Oblique Muscle Palsy
Published 2024-12-01“…Complete success was defined as achieving postoperative orthotropia in addition to the resolution of diplopia and head tilt. …”
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59529
Assessment of Acid Mining Drainage (AMD) Formation in the Ore Stock and Waste Dam Reservoir Areas: An example of Gümüşhane
Published 2018-06-01“…Besides, AMD is not likely to occur in a short-term period according to very low S-2 values. In addition, compacted clay (50 cm thick) was laid in order to make impermeable in the stock area, and the resulting vertical profile was modeled in the finite element network system and water discharges determined. …”
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59530
Structural study, optical properties, thermal stability, and biological activity of a non-centrosymmetric hybrid compound 3,4-Diaminopyridinium perchlorate (3,4-DAPP)
Published 2025-03-01“…Furthermore, the thermal behavior studied by (TGA-DTA) and differential calorimetry (DSC) appears to have stability up to 280 °C. Additionally, the optical properties were investigated by UV–Vis absorption and photoluminescence spectroscopy, which exhibit emission property, and a band gap energy of 3.9 eV. …”
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59531
Formaldehyde-free wood adhesives based on protein materials from various plant species
Published 2025-03-01“…Protein-rich materials (e.g., soybean isolate) generally exhibited higher dry shear strengths (>10 N/mm²) compared to materials with lower protein content (<7 N/mm²). …”
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59532
Chromosome‐Level Genome Assembly and Whole‐Genome Resequencing Revealed Contrasting Population Genetic Differentiation of Black Bream (Megalobrama skolkovii) (Teleostei: Cyprinidae...
Published 2025-01-01“…Some key genes related to reproductive processes, body size development, and muscle metabolism were found under selection in the northern population, possibly responsible for its local adaptation. …”
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59533
Optimizing Image Feature Extraction with Convolutional Neural Networks for Chicken Meat Detection Applications
Published 2025-01-01“…Finally, in the third phase, additional filters, such as Histogram of Oriented Gradients (HOG), Local Binary Pattern (LBP), and saliency, were incorporated to extract complementary features from the images, without discontinuing the use of a CNN for processing. …”
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59534
Probiotic Amelioration of Azotemia in 5/6th Nephrectomized Sprague-Dawley Rats
Published 2005-01-01“…Subsequently, blood (retro-orbital) and urine (collected for measurements of blood urea-nitrogen and creatinine respectively), body weight and bacterial counts (feces) were obtained at regular intervals. …”
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59535
Genotypic variability of Pinus sylvestris L. on the drought-resistance attribute
Published 2019-02-01“…The expediency of applying the biotechnological approach was proved by analysis of the gene expression level of stress proteins: the level of AbaH gene expression correlates greatly with the indicator of the viability of callus cultures, including ones on a nutrient medium with an additional stress agent (NaCl). Trees that can be assigned to drought-resistant ones, according to the results of the analysis, should be recommended for use in breeding.…”
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59536
Different immunological characteristics of asymptomatic and symptomatic COVID-19 patients without vaccination in the acute and convalescence stages
Published 2025-01-01“…Our study provides additional information on the immune status of COVID-19 patients with different clinical manifestations in different stages. …”
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59537
Antiamnesic and Neurotrophic Effects of Parkia biglobosa (Jacq.) R. Br (Fabaceae) Aqueous Extract on In Vivo and In Vitro Models of Excitotoxicity
Published 2025-01-01“…It also increased (p<0.01) the concentration of acetylcholine, reduced (p<0.001) that of malondialdehyde, and limited (p<0.001) neuroinflammation and neuronal loss (p<0.001). In addition, the extract (2450 μg/mL) increased (p<0.001) the percentage of viable cells. …”
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59538
Genetic basis of depressive disorders
Published 2019-07-01“…In addition, there is evidence of the involvement of HPA-axis genes (OXTR, AVPR1A, and AVPR1B), sex hormone receptors genes (ESR1, ESR2, and AR), neurotrophin (BDNF) and methylenetetrahydrofolate reductase (MTHFR) genes, neuronal apoptosis (CASP3, BCL-XL, BAX, NPY, APP, and GRIN1) and inflammatory system (TNF, CRP, IL6, IL1B, PSMB4, PSMD9, and STAT3) genes in DD development. …”
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59539
Integration of Generative Artificial Intelligence in Higher Education: Best Practices
Published 2024-12-01“…The results highlight several opportunities around the use of GenAI in education, including improving writing, creating educational resources, supporting lesson planning, and increasing teacher productivity. In addition, significant challenges were identified, such as the ethical use of AI and strategies for detecting AI-generated text. …”
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59540
Immunopathological Changes of Streptococcus pneumoniae Causing Respiratory Infection in Lambs
Published 2024-12-01“…The blood samples were collected from all animal groups at day zero before pneumoniae induction and 3, 6, and 14 days post infection for total and differential white blood cell count (WBCs) and tumor necrosis factor-alpha (TNF-α) assessments. Additionally, on days 6 and 14 post-exposure, trachea and lung tissue samples were harvested for macroscopic and microscopic pathological changes evaluation. …”
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