Immunogenicity and safety of the MF59-adjuvanted seasonal influenza vaccine in non-elderly adults: A systematic review and meta-analysis. by Alexander Domnich, Carlo-Simone Trombetta, Elettra Fallani, Marco Salvatore

“…This immunogenicity advantage was more pronounced in immunosuppressed adults. Additionally, aTIV/aQIV was more immunogenic than non-adjuvanted counterparts towards heterologous A(H3N2) strains with a 10.7% (95% CI: 3.2%, 18.2%) difference in seroconversion rates. …”
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Understanding hospital length of stay in trauma laparotomy patients: a National Trauma Database Study by Jeremy Grushka, Kosar Khwaja, Hayaki Uchino, Evan G Wong

“…Penetrating mechanisms, particularly stab wounds, were strongly associated with a short HLOS. Additionally, isolated abdominal trauma, splenic injuries or spleen-related procedure were more likely to result in a short HLOS. …”
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Sub-Clinical Regional Macular Changes in Self-Reported Diabetic Subjects: Vascular and Retinal Layer Analysis Using Swept-Source OCT by Challa NK, Alghamdi WM, Alluwimi MS, Alshammeri S

“…The FAZ was manually mapped at the SCP on OCTA images.Results: In diabetic subjects, the superficial capillary plexus vessel density (SCPVD) was significantly lower in both the central (P = 0.04) and inferior (P = 0.01) regions compared to the control group. Additionally, diabetic patients showed a significant reduction in temporal macular thickness (MT) and thinning of the ganglion cell layer (GCL) in all three quadrants except in the central and inferior macula (P < 0.05). …”
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The Number of Frames on ECG-Gated 18F-FDG Small Animal PET Has a Significant Impact on LV Systolic and Diastolic Functional Parameters by Christoph Eissler, Rudolf A. Werner, Paula Arias-Loza, Naoko Nose, Xinyu Chen, Martin G. Pomper, Steven P. Rowe, Constantin Lapa, Andreas K. Buck, Takahiro Higuchi

“…EDV significantly increased by numbers of frames (353.8 ± 57.7 μl∗, 380.8 ± 57.2 μl∗, 398.0 ± 63.1 μl∗, and 444.8 ± 75.3 μl at 4, 8, 12, and 16 frames, respectively; ∗P<0.0001 vs. 16 frames), while systolic (EF) and diastolic (TPF, 1/3 FR and PFR) parameters were not significantly different between 12 and 16 frames. In addition, significant differences between diabetic and control animals in 1/3 FR and PFR in 16 frames per cardiac cycle were observed (P<0.005), but not for 4, 8, and 12 frames. …”
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Evaluating a system-wide, safety investigation in healthcare course in Norway: a qualitative study by Carl Macrae, Siri Wiig, Veslemøy Guise, Cecilie Haraldseid-Driftland, Lene Schibevaag, Janne Gro Alsvik, Adriana Rosenberg

“…In 2019, a new master’s level course in Safety Investigation in Healthcare was established to support the training and development of a new team of investigators from an independent investigatory body. The course was established at one Norwegian university and a total of 19 students were enrolled and completed the course. …”
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Simultaneously Enhanced Permeability and Selectivity of Pebax-1074-Based Mixed-Matrix Membrane for CO₂ Separation by Rujing Hou, Junwei Xie, Yawei Gu, Lei Wang, Yichang Pan

“…Both the strengthened CO₂ solubility coefficients coming from the additional CO₂ adsorption sites of amino groups in BPEI and the reinforced CO₂ diffusivity coefficients originating from the fast transport channels created by KAUST-8 led to the promising CO₂ separation performance for KAUST-8@BPEI/Pebax-1074 MMM. …”
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Simulation study on catalytic oxidation of low concentration mine gas in an oxidation device by Yuhang Liu, Xijian Li, Qi Xiao, Xingfa Jiang, Weilai Dong, Xianyong Chen, Yuyan Feng

“…Under conditions where the methane concentration is between 1.6 and 1.8 vol%, the appropriate switching time is 30–60 s, and the amount of hot air extraction should be maintained within the range of 15–20% to achieve efficient combustion and heat transfer performance. Additionally, the placement of the catalyst needs to be finely adjusted according to the changes in the internal temperature field of the oxidation device to ensure the maximization of catalytic effects. …”
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The impact of the Hsp67Bc gene product on Drosophila melanogaster longevity, fecundity, and acute heat stress tolerance by D. Malkeyeva, S. A. Fedorova, E. Kiseleva

“…We explain this phenomenon by a reduced number of ovarioles in Hsp67Bc-null females and enhanced macroautophagy in their germaria, which promotes the death of forming egg chambers. In addition, short heat stress (37 °C, 2 h), which increased the control line’s longevity (an effect common for a wide range of organisms), had a negative impact on the lifespan of Hsp67Bc-null f lies. …”
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NADPH Oxidase 2-Mediated Insult in the Auditory Cortex of Zucker Diabetic Fatty Rats by Zheng-De Du, Wei Wei, Shukui Yu, Qing-Ling Song, Ke Liu, Shu-Sheng Gong

“…Expression of 8-hydroxy-2-deoxyguanosine (8-OHdG), a marker of DNA oxidative damage, was also increased in the neuronal mitochondria of the auditory cortex of ZDF rats. Additionally, decreases in the mitochondrial total antioxidant capabilities (T-AOC), adenosine triphosphate (ATP) production, and mitochondrial membrane potential (MMP) were detected in the auditory cortex of ZDF rats, suggesting mitochondrial dysfunction. …”
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Efficacy of vericiguat in patients with chronic heart failure and reduced ejection fraction: a prospective observational study by Yinge Zhan, Liu Li, Jie Zhou, Yishan Ma, Xuchong Guan, Suo Wang, Ya Chang

“…At six months, the Vericiguat group exhibited a significant reduction in patients classified as C (from 31.6 to 7.5%) and D (from 31.6 to 3.7%), with P values less than 0.05. Additionally, Vericiguat significantly improved Peak Oxygen Consumption (from 14.24 ± 6.21 to 19.03 ± 4.87 ml/kg/min) and Anaerobic Threshold (from 10.48 ± 3.82 to 13.48 ± 3.31 ml/kg/min). …”
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An Improved YOLOv8 Model for Strip Steel Surface Defect Detection by Jinwen Wang, Ting Chen, Xinke Xu, Longbiao Zhao, Dijian Yuan, Yu Du, Xiaowei Guo, Ning Chen

“…Second, we integrate a polarized self-attention (PSA) mechanism to improve the model’s feature representation and enhance its ability to focus on relevant information. Additionally, we incorporate the BAM attention mechanism after the C2f module to strengthen the model’s feature selection capabilities. …”
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Evaluation of a Commercial Multiplex Real-Time PCR with Melting Curve Analysis for the Detection of <i>Mycobacterium tuberculosis</i> Complex and Five Nontuberculous Mycobacterial... by Keun Ju Kim, Yunhee Chang, Seung Gyu Yun, Myung-Hyun Nam, Yunjung Cho

“…Notably, it identified additional mycobacterial nucleic acids not detected by the LPA in eight isolates. …”
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Antimicrobial and Mechanical Properties of Orthodontic Acrylic Resin Containing Zinc Oxide and Titanium Dioxide Nanoparticles Supported on 4A Zeolite by Mahdiyeh Esmaeilzadeh, Baharak Divband, Bahram Ranjkesh, Fatemeh Pournaghi Azar, Fatemeh Yeganeh Sefidan, Mojgan Kachoei, Behnaz Karimzadeh

“…XRD confirmed the accurate crystalline structure of synthesized nanoparticles; FE-SEM images showed nanoparticle dispersion within polymerized acryl. The addition of 2 and 4 wt% of ZnO/4A, TiO2/4A, and ZnO/TiO2/4A caused colony reduction in all types of tested microorganisms more than 99% and 100%, respectively. …”
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Canadian healthcare capacity gaps for disease-modifying treatment in Huntington’s disease: a survey of current practice and modelling of future needs by Sylvain Chouinard, Blair R Leavitt, Angèle Bénard, Nathalie Budd, Jennifer W Wu, Kerrie Schoffer

“…Objectives Disease-modifying therapies in development for Huntington’s disease (HD) may require specialised administration and additional resource capacity. We sought to understand current and future capacity for HD management in Canada considering the possible introduction of an intrathecal (IT) disease-modifying treatment (DMT).Design, setting and participants Using a case study, mixed methods framework, online surveys followed by semistructured interviews were conducted in late 2020 and early 2021. …”
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Implementation of carceral medicaid suspension and enrollment programs: perspectives of carceral and medicaid leaders by Sachini Bandara, Brendan Saloner, Hannah Maniates, Minna Song, Noa Krawczyk

“…Discussion Findings highlight the need to update data sharing infrastructure, which will be critical to the implementation of the 1115 waivers, as carceral facilities will be subject to Medicaid billing and reporting requirements. In addition to investing in the ability to newly enroll and suspend Medicaid benefits, attention towards improving timely reactivation practices is needed, particularly given the highly elevated risk of mortality immediately after release. …”
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Characterizing the Flow and Interaction of Microbubbles in a 2D Capillary Network for Targeted Drug Delivery: A Simulation Study by Sadegh Shurche, Akram Shahidani, Roghaye Bodaghi Hossein Abadi

“… Purpose: Microbubble ultrasound contrast agents inside the bloodstream enhance the ultrasound signals of the vascular bed. In addition, microbubbles can be used for treatment. The present study assesses how air bubbles flow in a microchannel 2D capillary network. …”
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Tetrandrine Inhibits Titanium Particle-Induced Inflammatory Osteolysis through the Nuclear Factor-κB Pathway by Zige Liu, Yan Li, Fengying Guo, Chen Zhang, Guorui Song, Jiahao Yang, Desheng Chen

“…Tartrate-resistant acid phosphate (TRAP) staining and transmission electron microscopy (TEM) demonstrated that osteoclast formation was remarkably inhibited in the groups treated with Tet in a dose-dependent manner. In addition, relevant inflammatory cytokines (tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6) were also significantly reduced in the calvaria of the Tet-treated groups. …”
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Application of Conversational AI Models in Decision Making for Clinical Periodontology: Analysis and Predictive Modeling by Albert Camlet, Aida Kusiak, Dariusz Świetlik

“…The questions were additionally assigned to five types in accordance with the subject covered. …”
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Cosmic jurisdictions: quod lege naturae, moribus et consuetudine inductum est by M. I. Myklush, V. K. Marinich

“…At the same time, it is proposed to apply the principle of “Res Communis Humanitatus” to the “domestic room”, and the new principle of “Res Nullius Civitatis et Res Communis Animal Rationale” to the “alien room”. Additionally, the authors emphasize the fact that the above factors have already formed the structure of the “domestic room” regardless of the existing intentions and suggestions, leaving the world to recognize and accept it. …”
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Shear Stress Promotes Arterial Endothelium-Oriented Differentiation of Mouse-Induced Pluripotent Stem Cells by Yan Huang, Xiaofang Chen, Jifei Che, Qi Zhan, Jing Ji, Yubo Fan

“…Further, shear stress caused cells to align parallel to the direction of the flow, induced cells forming functional tubes, and increased the secretion of nitric oxide. In addition, Notch1 was significantly upregulated, and the Notch ligand Delta-like 4 was activated in response to shear stress, while inhibition of Notch signaling by DAPT remarkably abolished the shear stress-induced arterial epithelium differentiation. …”
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