Odontogenic differentiation of dental pulp stem cells by glycogen synthase kinase-3β inhibitory peptides by Vidhyashree Rajasekar, Mohamed Mahmoud Abdalla, Mohammed S. Basbrain, Prasanna Neelakantan, Cynthia KY Yiu

“…Specifically, L803-mts showed significantly greater ALP activity and mineralization compared to the other peptides and the controls (p < 0.05). Additionally, L803-mts showed a significant increase (p < 0.05) in the expression of DSPP, DMP-1, Runx-2, along with increased protein expression of DSPP and DMP-1 compared to the control. …”
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Prediction of α-Solanine and α-Chaconine in Potato Tubers from Hunter Color Values and VIS/NIR Spectra by Shimeles Tilahun, Hee Sung An, In Geun Hwang, Jong Hang Choi, Min Woo Baek, Han Ryul Choi, Do Su Park, Cheon Soon Jeong

“…Concurrently, equations were developed from color variables in multiple regression with r-values of 0.76 and 0.71 for α-solanine and α-chaconine, respectively. Additionally, the selected PLS model of VIS/NIR spectra had promising predictive power for α-solanine and α-chaconine with r-values of 0.68 and 0.63, respectively, between measured and predicted samples. …”
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Antidiabetic Rosiglitazone Reduces Soluble Intercellular Adhesion Molecule-1 Level in Type 2 Diabetic Patients with Coronary Artery Disease by Guang Wang, Zhe Zhang, Jie Yu, Fuchun Zhang, Liyun He, Jinru Wei, Jieming Mao, Xian Wang

“…After 6-month rosiglitazone treatment, plasma levels of sICAM-1 were lower than baseline and control group levels (370.4 (332.4–421.9) pg/mL versus 423.5 (327.4–500.3) pg/mL and 404.6 (345.2–483.4) pg/mL, P<.001). In addition, plasma levels of C-reactive protein were significantly reduced from baseline levels. …”
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PSMA antibody, humanized PSMA.CAR10.3, or Cetuximab increases prostate cancer localization of NF-κB p50-deficient immature myeloid cells (p50-IMC) and phagocytosis by their macroph... by Mohammad A. Alzubi, Theresa Barberi, Alan D. Friedman

“…Tumor localization is further increased when myelo-depleting 5-fluorouracil precedes p50-IMC administration. Additionally, we find that PSMA Ab, EGFR Ab, or PSMA.CAR10.3 increase in vitro phagocytosis of Myc-CaP cells expressing PSMA or EGFR by p50-IMC-derived macrophages, including in M2-promoting IL-4, which is a component of the immune-suppressive tumor microenvironment. …”
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Risk factors of chronic kidney disease in cisplatin-based hyperthermia intraperitoneal chemotherapy by Chih-Chung Cheng, Hung-Chieh Yeh, Pei-Wen Su, Chien-Lin Ho, Sheng-Chi Chang

“…Clinicians should exercise caution in prescribing parecoxib during HIPEC procedures. Additionally, maintaining intraoperative body temperature below 38.5°C might be crucial to mitigate the risk of CKD development. …”
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Tumor-derived exosomal lncRNA-MIR193BHG promotes bone metastasis of breast cancer by targeting the miR-489-3p/DNMT3A signaling axis in osteoclasts by Xiaoya Liu, Rui Ma, Feng Wei, Maihuan Wang, Yiwei Jiang, Peng Zheng, Zhen Cao

“…Knockdown experiments demonstrated that reducing the levels of exosomal lncRNA-MIR193BHG significantly inhibited osteoclast differentiation and bone resorption, which was confirmed both in vitro and in vivo. Additionally, mechanistic studies revealed that lncRNA-MIR193BHG acted as a competitive endogenous RNA (ceRNA) interacting with miR-489-3p, regulating DNMT3A expression and subsequently affecting osteoclast differentiation. …”
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Life cycle management of capital construction object with minimization of atmospheric air pollution by V. N. Azarov, O. V. Burlachenko, A. O. Burlachenko, M. D. Azarova

“…An information support system was built, which, unlike the applied methods, makes it possible to make decisions on the LC CCO management, not only taking into account the technical and economic efficiency of the compared options, but also the degree of atmospheric air dust pollution. In addition, the developed information support allows you to take into account the fact that certain events occurrence is random during the LC CCO with the determination of their occurrence probability.…”
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Clinical Effect on Early Rehabilitation Intervention of Patients after Coronary Artery bypass Grafting by Xin HE, Weiming ZHANG, Xin CHEN, Huijuan PAN, Yuanfeng SUN

“…On the 7th day after the operation, quality of life assessment, pain,6-min walking test and mental status were performed to compare the health status, psychological status, and the relative walking distance were compared between the two groups.Results:On the 7th day after the operation,6-min walking test and the modified Barthel index (MBI) in the rehabilitation group were (354.75±85.83) metres and (92.79±5.34) scores respectively, which were significantly higher than the (295.60±67.83) metres and (83.82±6.22) scores in the control group (<italic>P</italic>&lt;0.001). In addition, visual analogue scale (VAS) scores, Hamilton depression scale (HAMD) scores and Hamilton anxiety scale (HAMA) scores in the rehabilitation group were (1.19±0.55) scores, (10.46±8.21) scores and (11.36±4.87) scores respectively, which were significantly lower than those of the control group[ (1.88±1.29) scores, (17.22±6.15) scores, (19.58±6.72) scores, <italic>P</italic>&lt;0.001].Conclusion:Early in-hospital cardiac rehabilitation intervention can effectively increase the 6-min walking distance, improve the patients'mental status and quality of life, and relieve pain.…”
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Clinical application of oral Chinese Patent Medicines in ophthalmology: a scoping review protocol by Wei Zhou, Kai Xu, Ziyang Huang, Xiaoyu Li, Xing Liao, Lina Liang, Yamin Li, Qianqian Zuo

“…Introduction The prevalence of eye diseases has been increasing worldwide. In China, in addition to conventional medicine, Traditional Chinese Medicine (TCM) plays an important role in maintaining people’s vision health. …”
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Sustainability assessment of single-atom catalysts in the transition to greener chemical processes by Mark A. Bajada, Maxim Tschulkow, Gianvito Vilé

“…These catalysts are also recyclable and operate under moderate conditions, resulting in fewer harmful emissions, reduced energy consumption, and lower costs for everyday products—from medicines and personal care items to food additives. Furthermore, the study highlights that using renewable energy sources to power these processes directly supports global efforts to reduce reliance on fossil fuels. …”
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Immunoglobulin G4-related disease with pleural involvement in an 80-year-old female patient: A case report and literature review by Liying Zhang, Li Mo

“…Methods: We report a case of IgG4-RD involving the pleura in an 80-year-old woman with a weight of 62 kg and a body mass index (BMI) of 23.2 kg/m2. Additionally, we reviewed pleural biopsy-confirmed IgG4-RD cases in the PubMed, Scopus, Web of Science, Embase, and Science Direct databases. …”
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Historical aspect of the european understanding of the rule of law by Kelbya S.

“…It was determined that although Ukraine has taken significant steps to prevent corruption since independence, the country’s legal system still requires significant changes.It is also found that the current state of the European rule of law shows mixed trends. In addition, leading European countries not only demonstrate successful models of the rule of law, but also actively support Ukraine in implementing such standards through various technical assistance programs and expert advice. …”
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Shared rare genetic variants in multiplex autism families suggest a social memory gene under selection by Kang Seon Lee, Taeyeop Lee, Mujun Kim, Elizaveta Ignatova, Hyo-Jeong Ban, Min Kyung Sung, Younghoon Kim, Youn-Jae Kim, Jin-Hee Han, Jung Kyoon Choi

“…One variant in this family was 6 bp away from human-specific trinucleotide fixation. Additionally, CRISPR/Cas9 experiments demonstrated downregulation by a family variant and upregulation by a fixed site. …”
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MEG3 Alleviated LPS-Induced Intestinal Injury in Sepsis by Modulating miR-129-5p and Surfactant Protein D by Xianjin Du, Dan Tian, Jie Wei, Chen Yan, Peng Hu, Xu Wu, Wenbin Yang

“…Subsequently, to induce the inflammatory injury of sepsis, human colorectal Caco2 cells were treated with 10 ng/ml LPS. 10 ng/ml LPS significantly inhibited Caco2 cell proliferation and increased the apoptosis. Additionally, MEG3 was decreased whereas miR-129-5p was obviously increased in Caco2 cells incubated with LPS. …”
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Translations of Yarliqs of the Crimean khans to the Je­wish Community of Kyrk-Yer (Chufut-Kale) in the Archives of the Russian Federation (According to the Materials of the State A... by Prokhorov D.A.

“…This document is particularly important because its original has not survived. Additionally, materials of the fund 241 “Taurida and Odessa Karaite Spiritual Government” of the State Archive of the Republic of Crimea (GARK) were found to contain documents, reporting the translations of the decisions of the “Kadiasker court”, as well as fermans to the Kyrk-Yer Jewish community of khans: Saadet-Girey I (1524), Inayet-Girey (1635), Mohammed-Girey IV (1642), Murad-Girey (1678–1683) and Saadet-Girey IV (1717–1724). …”
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Seasonal Variability of PM10 Chemical Composition Including 1,3,5-triphenylbenzene, Marker of Plastic Combustion and Toxicity in Wadowice, South Poland by Przemysław Furman, Katarzyna Styszko, Alicja Skiba, Damian Zięba, Mirosław Zimnoch, Magdalena Kistler, Anne Kasper-Giebl, Stefania Gilardoni

“…The co-combustion of plastic in addition to conventional fuels and the respective impact on air quality is evaluated via the concentration of the marker compound 135TPB. …”
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Exploring molecular determinants and pharmacokinetic properties of IgG1-scFv bispecific antibodies by Kristina M.J. Aertker, Minu Ravindra Pilvankar, Tobias M. Prass, Michaela Blech, Fabian Higel, Srinath Kasturirangan

“…These interactions likely stabilize the BsAb FcRn interaction at physiological pH, which in turn could disrupt FcRn-mediated BsAb recycling. In addition to the empirical observations, we also evaluated the impact of in silico properties, including pI differential between the Fab and scFv and the ratio of dipole moment to hydrophobic moment (RM) and their correlation with the observed clearance. …”
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The influence of selected financial factors on the survival of SMES in V4 countries by Zdenko Metzker, Roman Hlawiczka, Irma Tabaku, Ho Thanh Tung

“…Central to the investigation is understanding how managerial comprehension of critical financial management aspects, the willingness to embrace financial risks, and effective risk management contribute to a company’s enduring success. Additionally, the study assesses how a positive evaluation of a company’s financial performance correlates with its overall longevity in the business landscape.Results indicate that financial management significantly influences SME stability in the medium term. …”
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Uniaxial Compression Creep Relaxation and Grading of Coal Samples via Tests on the Progressive Failure Characteristics by Zuqiang Xiong, Changsheng Song, Chengdong Su, Xiaolei Wang, Cheng Wang, Yu Hao

“…For fully mechanized coal faces, increasing the support resistance and timely moving the support after coal cutting may prevent rib spalling accidents by reducing coal stress and exposure time in the front of the working face. Additionally, routine uniaxial compressive failures showed a simple form, having a clear tension-shear dual rupture surface. …”
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Effect of blindfolding the lead resuscitator on frequency of closed-loop communication during veterinary cardio-pulmonary resuscitation training: a randomized, controlled pilot stu... by Olivia X. Walesby, Giacomo Stanzani, Lindsay Kellett-Gregory, Mayank Seth, Emily K. Thomas

“…ObjectiveTo evaluate the effect of blindfolding the lead resuscitator during veterinary cardiopulmonary resuscitation (CPR) simulation training sessions on frequency of completed closed-loop communication statements (CLC).DesignTen groups of staff volunteers were recruited for a prospective, randomized, blinded, observational pilot study over a 6-month period. Additionally, two associated online questionnaires were completed by participants.SettingPrivate veterinary referral hospital in the United Kingdom.InterventionForty volunteers were randomly allocated into ten groups of four. …”
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