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59001
Identification of hub genes, non-coding RNAs and pathways in Renal cell carcinoma (RCC): A comprehensive in silico study
Published 2025-03-01“…We constructed a competitive endogenous RNA (ceRNA) network involving lncRNAs, circRNAs, and miRNAs, suggesting complex regulatory interactions that drive KIRC pathogenesis.Additionally, the study examined drug sensitivity associated with the expression of hub genes, revealing the potential for personalized treatments. …”
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59002
Heterogeneity Effect of Human Disturbances on Landscape Patterns in the Yellow River Delta Wetland, China
Published 2024-12-01“…A pixel-based Human Disturbance Index (HDI) with the addition of ecological conditions and the buffer influence is first established to quantify the spatial difference of human disturbances. …”
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59003
Serum connexin 26 as a potential marker of non-syndromic hearing loss
Published 2025-01-01“…Results We found that the connexin 26 level by ELISA was significantly lower in patients compared to controls (p = 0.0001). In addition, there was a significant negative correlation between connexin 26 levels and the degree of hearing loss by audiometry (r = − 0.403, p < 0.0001). …”
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59004
Comparison of Morphological and Functional MRI Assessments of Periprostatic Fat for Predicting Prostate Cancer Aggressiveness
Published 2025-01-01“…Conclusions: The ADC value of periprostatic fat may serve as an additional tool for PCa risk stratification, correlating with poorer outcomes such as systemic recurrence and overall survival. …”
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59005
Realization of malignant potential of human glioblastoma mitochondria in immunodeficient animals
Published 2023-09-01“…Stained granules with the corresponding immunohistochemical profile, GFAP and ki-6, were clearly defined in the mesentery and lymph node of a Balb/c Nude mouse (N = 6) aſter transplantation of human glioblastoma mitochondria. …”
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59006
Multi-view knowledge representation learning for personalized news recommendation
Published 2025-01-01“…The multi-head attention dynamically weighs user interactions and candidate news based on relevance, enhancing recommendation accuracy. Additionally, MKRL’s multi-view approach represents news from different perspectives, enabling richer and more personalized recommendations. …”
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59007
<i>Hylomecon japonica</i>: A Review About Botanical Aspects, Traditional Applications, Chemical Composition, and Pharmacological Properties
Published 2025-01-01“…Notably, alkaloids and saponins have shown significant anti-tumor and antibacterial effects. Additionally, extracts of <i>Hylomecon japonica</i> have demonstrated promising activity in anti-inflammatory, anti-obesity, and varicose vein treatment applications. …”
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59008
Differentially expressed transcript isoforms associate with resistance to tuberculin skin test and interferon gamma release assay conversion.
Published 2023-01-01“…These findings should be validated with additional RSTR cohorts and whether the newly identified candidate resistance genes directly influence the monocyte Mtb response requires functional study.…”
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59009
Establishment of predictive models for head loss and filtration efficiency of pontoon mesh rotary filter based on dimension analysis
Published 2025-02-01“…In the test range, the optimal working condition of this filter was a flow rate of 930 L1 h−1, sand content of 2.0 g1 L−1, and 0.150 mm aperture of the filter screen. In addition, the head loss under this condition was 0.281 m, and the filtration efficiency was 84.01%. …”
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59010
Effectiveness of pre-employment card policy on employment transition during covid-19: evidence from Indonesian dual labor market
Published 2024-11-01“…The findings reveal that the PEC policy significantly increases the likelihood of unemployed individuals securing formal sector jobs rather than informal ones, with participants who completed the initial PEC training showing a 30% higher probability of transitioning to formal employment compared to those without PEC support. Additionally, the policy supports transitions within the labor market by facilitating movement from the informal to the formal sector, with an observed 25% increase in formal employment uptake among informal workers participating in PEC. …”
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59011
Neural correlates of basketball proficiency: An MRI study across skill levels
Published 2025-01-01“…Compared with NI group, AB and IB groups showed strengthened VMHC in supplementary motor area, paracentral lobule and superior frontal gyrus. Additionally, the ALFF of left middle occipital gyrus and right hippocampal and the GM density of left medial superior frontal gyrus exhibited differences in AB-IB and AB-NI comparisons. …”
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59012
$$\rho $$ ρ meson transverse momentum-dependent parton distributions
Published 2025-01-01“…Furthermore, the x-moments of $$\rho $$ ρ meson PDFs indicate that $$\langle x\rangle _{g_L}$$ ⟨ x ⟩ g L is larger using LFWFs than with the covariant approach. Additionally, analysis of quark spin densities within the $$\rho $$ ρ meson reveals that $$\rho _{\uparrow \downarrow }\left( k_x,k_y\right) =f-g_L-\frac{1}{3}f_{LL}$$ ρ ↑ ↓ k x , k y = f - g L - 1 3 f LL yields a negative result using the covariant approach, whereas $$\rho _{\uparrow \downarrow }\left( k_x,k_y\right) $$ ρ ↑ ↓ k x , k y derived from LFWFs produces a positive outcome.…”
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59013
Human Strategy Learning-Based Multi-Agent Deep Reinforcement Learning for Online Team Sports Game
Published 2025-01-01“…Nevertheless, applying multi-agent reinforcement learning-based AI in commercial online basketball games presents significant challenges, particularly in ensuring real-time processing, which requires efficient methods for managing observational data. In addition, the stochastic nature of action selection in reinforcement learning complicates the accurate learning of behaviors through explicit decision data. …”
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59014
Emerging Strategies in Cartilage Repair and Joint Preservation
Published 2024-12-01“…Gene-editing tools like CRISPR/Cas9 have facilitated targeted cellular modifications, while novel biomaterials such as hydrogels, biodegradable scaffolds, and 3D-printed constructs have improved mechanical support and tissue integration. Additionally, biophysical stimuli like low-intensity pulsed ultrasound (LIPUS) and electromagnetic fields (EMFs) have enhanced chondrogenic differentiation and matrix production. …”
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59015
Plasma microRNA signatures predict prognosis in canine osteosarcoma patients.
Published 2024-01-01“…In both multiple miRNA and multiple variable models, miR-214-3p was always the first decision point with high expression consistently predicting a worse prognosis. Additional miRNAs in combination with low expression of miR-214-3p similarly had a worse prognosis demonstrating better outcome prediction using multiple miRNAs compared to using miR-214-3p alone. …”
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59016
Intratumoral <i>Fusobacterium nucleatum</i> in Pancreatic Cancer: Current and Future Perspectives
Published 2024-12-01“…<i>Fn</i> engages in pancreatic tumorigenesis and metastasis through multifaceted mechanisms, including immune response modulation, virulence factors, control of cell proliferation, intestinal metabolite interactions, DNA damage, and epithelial–mesenchymal transition. Additionally, compelling research suggests that <i>Fn</i> may exert detrimental effects on cancer treatment outcomes. …”
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59017
Assessing microbial population dynamics, enzyme activities and phosphorus availability indices during phospho-compost production
Published 2018-11-01“…Compost piles without GPR addition were included as control. Compost samples were taken at mesophilic, thermophilic, cooling–stabilization and maturing phases for microbial counts, enzyme activities and P assessment. …”
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59018
Multilevel Structural Characteristics of Jinshajiang Main Fault and Its Influence on Engineering
Published 2022-01-01“…Taking the outcrop of fracture zones of Batang section, Jinshajiang main fault in the Qinghai-Tibet Plateau as the research object, the geometric characteristics of rock masses, the particle size, mineral composition, and mechanical characteristics of rocks in the fault are studied through field investigation, geological mapping, mineral composition analysis, and mechanical tests. In addition, a displacement model of multilevel structure fault is presented by numerical simulation. …”
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59019
Circular Economy Alternative Repurposing Textile Solid Discarded Materials from the Leather Goods Sector in Ubrique (Cádiz), Southern Spain
Published 2024-12-01“…By implementing a circular alternative that uses just 8.75% of these materials, an economic saving of around EUR 750 per year was reached. In addition, a low-cost vacuum molding method was tested for producing stoppers, yielding aesthetically pleasing and durable prototypes. …”
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59020
Adiponectin Gene Polymorphisms and Possible Susceptibility to Metabolic Syndrome among the Sudanese Population: A Case-Control Study
Published 2023-01-01“…This study aimed to determine the allelic genotypes and haplotypes distribution of the ADIPQ gene polymorphisms and its association with body mass index (BMI), waist circumference (WC), glycated hemoglobin (HbA1c), and lipid profile in MetS adult Sudanese patients. …”
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