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58741
Pyrrocidines A and B demonstrate synergistic inhibition of Fusarium verticillioides growth
Published 2025-01-01“…Further, results provided evidence that FvZBD1 confers partial tolerance to pyrrocidines, particularly pyrrocidine A, and that pyrrocidine functions through FvZBD1 to effectively eliminate fumonisin biosynthesis. Additionally, we showed that the FvABC3 (FVEG_11089) mutant, earlier described as hypersensitive to pyrrocidine, is particularly sensitive to pyrrocidine B. …”
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58742
Macrophage Migration Inhibitory Factor Interacting with Th17 Cells May Be Involved in the Pathogenesis of Autoimmune Damage in Hashimoto’s Thyroiditis
Published 2015-01-01“…MIF mRNA, IL-17A mRNA expressions and Th17 cells percentages, serum MIF, and IL-17A protein levels were all significantly higher in HT patients, even in euthyroid subgroup. Additionally, the differences became more obvious in dysfunction subgroup. …”
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58743
Benchmarking Vision-Based Object Tracking for USVs in Complex Maritime Environments
Published 2025-01-01“…We benchmarked the performance of seven distinct trackers, developed using advanced deep learning techniques such as Siamese Networks and Transformers, by evaluating them on both simulated and real-world maritime datasets. In addition, we evaluated the robustness of various control algorithms in conjunction with these tracking systems. …”
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58744
Sensitive Detection of Lasalocid Residue in Chicken by Surface Enhanced Raman Spectroscopy
Published 2025-02-01“…Results showed that AuNPs with a particle size of 40 nm had good enhancement effect, the SERS characteristic peak of LAS was at 1118 cm−1, the AuNPs substrate had good reproducibility, and the optimal addition concentration of HNO3 was 0.5 mol/L. The linear range of this method was 0.55×10−6~0.55 mg/mL, the detection limit was 0.23 ng/mL, the recovery rate of chicken samples was 91.9%~107.3%, and the relative standard deviation was 3.6%~5.7%, which was consistent with the detection results of the national standard method (GB31613.5-2022). …”
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58745
Liangxue Tongyu Prescription exerts neuroprotection by regulating the microbiota-gut-brain axis of rats with acute intracerebral hemorrhage
Published 2025-01-01“…Analysis via western blot, quantitative real-time PCR, immunohistochemistry (IHC) and tunel staining indicated that LTP upregulated the expression of brain-derived neurotrophic factor (BDNF) and nerve growth factor(NGF) and reduced neuronal cell apoptosis. Additionally, 16S rDNA sequencing revealed that LTP mitigated dysbiosis of intestinal microbiota in AICH rats. …”
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58746
Achieving precipitation strengthening and retained austenite thinning via strain induced precipitation to improve fatigue wear resistance of bainitic steel
Published 2025-01-01“…Since fatigue performance exhibited different dominance over wear performance under different wear conditions, the amount ratio of primary TiC to strain-induced TiC can be altered by adjusting the Ti addition to meet the requirements of fatigue performance under different wear conditions.…”
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58747
Quantification of Pregenomic RNA and Covalently Closed Circular DNA in Hepatitis B Virus-Related Hepatocellular Carcinoma
Published 2013-01-01“…In conclusion, cccDNA and pgRNA are detected and represented HBV replication not only in noncancerous but also in cancerous liver tissues. In addition, the replication is shown in not only patients with HBsAg-positive but also occult HBV-infected patients, suggesting the contribution to HCC development.…”
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58748
Comprehensive analysis of ESCRT transcriptome-associated signatures and identification of the regulatory role of LMO7-AS1 in osteosarcoma
Published 2025-01-01“…Moreover, ERG signature score was found to be associated with the response of OS patients to immunotherapy and anticancer drugs. Additionally, we constructed a prognostic signature consisting of 10 ESCRT-related long noncoding RNAs (ERLs) that effectively predicted the prognosis of OS patients. …”
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58749
Anthelmintic activity of 1,10-phenanthroline-5,6-dione-based metallodrugs
Published 2025-02-01“…Given the promising biological properties of phendione and its metal complexes, these findings contribute to the growing body of research seeking to address the urgent need for new anthelmintic therapies.…”
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58750
Urbanization enhances consumer protist-driven ARGs dissemination in riverine ecosystems
Published 2025-01-01“…We collected water samples from the highly urbanized (western: 65 % built land, sewage-affected) and lesser-urbanized (northern: 25 % built land, drinking water source) downstream tributaries of the Jiulong River in southeast China over dry and wet seasons. We utilized metagenomic and amplicon (16S and 18S rDNA) sequencing to investigate the relationships among microeukaryotic algae, consumer protists, bacterial communities, and the resistome. …”
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58751
Maturation of the biofloc system in Penaeus vannamei culture under different salinities and its effects on the microbial communities
Published 2025-03-01“…Bacteria that convert ammonia to nitrite matured more rapidly at low salinity (11 ppt), while bacteria that convert nitrite to nitrate matured faster at high salinity (44 ppt). Additionally, this study shows that microbial communities can shift significantly through the maturation process depending on competitive dynamics and the metabolic requirements of bacteria. …”
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58752
Evaluation of the diagnostic efficiency of fluorescence in situ hybridization for pulmonary tuberculosis: a systematic review and meta-analysis
Published 2025-01-01“…QUADAS-2 was used to evaluate the literature’s quality. We used Meta-DiSc software to create forest plots.ResultsThe search yielded 7 studies, involving 1,224 sputum samples that could be included in our meta-analysis. …”
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58753
Dendrobium chrysotoxum Lindl. Alleviates Diabetic Retinopathy by Preventing Retinal Inflammation and Tight Junction Protein Decrease
Published 2015-01-01“…DC reduced the increased retinal mRNA expressions of intercellular adhesion molecule-1 (ICAM-1), tumor necrosis factor α (TNFα), interleukin- (IL-) 6, and IL-1β in diabetic rats. In addition, DC alleviated the increased 1 and phosphorylated p65, IκB, and IκB kinase (IKK) in diabetic rats. …”
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58754
Challenges in safe environmental applications of biochar: identifying risks and unintended consequence
Published 2025-01-01“…Furthermore, it provides a thorough overview of the adverse effects on animals, plants, microorganisms, and human health, elucidating the mechanisms of pollutant release, aging, and nano-effects from environmental geochemical processes involving biochar. Additionally, this review summarizes the environmental risk assessment methods of biochar, providing a reference for its safe application and the sustainable development of biochar-related research. …”
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58755
Long Time Series Spatiotemporal Variations in NPP Based on the CASA Model in the Eco-Urban Agglomeration Around Poyang Lake, China
Published 2024-12-01“…Scenic areas showed high forest cover and vigorous NPP changes, highlighting the need for targeted urban ecological management to enhance green development. Additionally, the seasonal fluctuations in NPP were notably influenced by specific land use types and local economic conditions. …”
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58756
Solar radiation estimation in West Africa: impact of dust conditions during the 2021 dry season
Published 2025-01-01“…The research focuses on a case study of a dust event in March 2021, which is characteristic of the dry season in West Africa. Significant desert aerosol emissions at the Bodélé Depression are associated with a Harmattan flow that transports the plume westwards. …”
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58757
Unraveling the degradation mechanism of multiple pyrethroid insecticides by Pseudomonas aeruginosa and its environmental bioremediation potential
Published 2025-01-01“…Strain PAO1 demonstrated effective soil bioremediation by removing etofenprox across different concentrations (25–100 mg·kg−1), with a degradation efficiency over 77 % within 15 days. Additionally, 16S rDNA high-throughput sequencing analysis revealed that introduction of strain PAO1 and etofenprox had a notable impact on the soil microbial community. …”
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58758
A novel imatinib analogue inhibitor of chronic myeloid leukaemia: design, synthesis and characterization—explanation of its folded conformation
Published 2025-01-01“…Crystallographic analysis reveals that PAPP1 consists of a phenyl–amino–pyridine–pyrimidine (PAPP) scaffold with substituted aromatic rings forming a nearly coplanar geometry. Additionally, supramolecular interactions in the crystal are mediated by hydrogen bonds and dispersion forces, forming dimers and layered structures. …”
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58759
Efficient regeneration protocol for producing true-to-type oil palm (Elaeis guineensis (jacq.) through somatic embryogenesis from immature male inflorescence
Published 2025-01-01“…The average embryogenesis percentage varied from. Additionally, the liquid media proved effective for root growth and proliferation (R2 medium), which included Indole-3-butyric acid (IBA) (2 mg/l) and NAA (0.5 mg/l), along with activated charcoal (100 mg/l). …”
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58760
Enhancing the Interfacial Property Between UHMWPE Fibers and Epoxy Through Polydopamine and SiO2 Surface Modification
Published 2025-01-01“…The mechanical property of modified UHMWPE/Epoxy composites was investigated, and 43.7 % improvement was obtained, compared with unmodified UHMWPE/Epoxy composite. Additionally, micro‐bond test revealed that the interfacial property (IFSS value) of modified UHMWPE fiber via the “one‐step” method was 6.08 MPa, significantly higher than that of unmodified UHMWPE fiber (2.47 MPa).…”
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