Standardizing and Classifying Anterior Cruciate Ligament Injuries: An International Multicenter Study Using a Mobile Application by Nadia Karina Portillo-Ortíz, Luis Raúl Sigala-González, Iván René Ramos-Moctezuma, Brenda Lizeth Bermúdez Bencomo, Brissa Aylin Gomez Salgado, Fátima Cristal Ovalle Arias, Irene Leal-Berumen, Edmundo Berumen-Nafarrate

“…Its high performance in predicting injury grades makes it a valuable addition to clinical practice for enhancing diagnostic precision and informing treatment planning.…”
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Soil microbiome interventions for carbon sequestration and climate mitigation by Gwyn A. Beattie, Anna Edlund, Nwadiuto Esiobu, Jack Gilbert, Mette Haubjerg Nicolaisen, Janet K. Jansson, Paul Jensen, Marco Keiluweit, Jay T. Lennon, Jennifer Martiny, Vanessa R. Minnis, Dianne Newman, Raquel Peixoto, Christopher Schadt, Jan Roelof van der Meer

“…Direct interventions include the introduction of microbial strains, consortia, phage, and soil transplants, whereas indirect interventions include managing soil conditions or additives to modulate community composition or its activities. …”
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CMACGSA: Improved Gravitational Search Algorithm Based on Cerebellar Model Articulation Controller for Optimization by Nazmiye Ebru Bulut, Emre Dandil, Ugur Yuzgec, Alpaslan Duysak

“…By employing the CMAC neural network, CMACGSA dynamically learns the masses of particles/agents of GSA, enabling a learning-driven approach to mass computation. Additional enhancements include Lévy mutation, boundary control methods and an error handling mechanism, which together improve the robustness and adaptability of the algorithm. …”
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Frequent Recurrences of Genital Herpes Are Associated with Enhanced Systemic HSV-Specific T Cell Response by Michal Holub, Alžběta Stráníková, Pavel Chalupa, Simona Arientová, Kateřina Roubalová, Ondřej Beran

“…Moreover, a trend of higher numbers of SFC was observed in these patients when compared with those with low frequency of GH recurrences (mean number of recurrences of 3.3 per year). Additionally, no differences in CD38 and HLA-DR expression on circulating CD8+ T cells were found among the study groups. …”
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Pomacea canaliculata hemocyanin as a novel natural immunostimulant in mammals by Ignacio Rafael Chiumiento, Ignacio Rafael Chiumiento, María Alejandra Tricerri, María Alejandra Tricerri, María Fernanda Cortéz, Santiago Ituarte, Santiago Ituarte, Julia Tau, Karina Valeria Mariño, Paola Lorena Smaldini, Horacio Heras, Horacio Heras, Marcos Sebastián Dreon, Marcos Sebastián Dreon

“…This species, known for its high reproductive rate and easy rearing, represents a promising source of potential biomedical compounds, including hemocyanin.MethodsEmploying flow cytometry, fluorescence microscopy, immunoassays, and quantitative PCR, we analysed the effects of PcH on THP-1 monocytes and their derived macrophages, as well as its ability to induce humoral response on C57BL/6 mice. Additionally, we evaluated the structural stability of PcH across a wide range of temperature and pH values.Results and discussionOur findings demonstrate that PcH is a structurally stable protein that not only triggers a pro-inflammatory effect on THP-1 derived-macrophages by increasing IL1-β and TNF-α levels, but also promotes phenotypic changes associated with the monocyte-to-macrophage differentiation. …”
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<i>Naegleria fowleri:</i> Portrait of a Cerebral Killer by Nguyen The Nguyen Phung, Huong Thien Pham, Thuc Thanh Tran, Vu Hoang Dinh, Nhut Minh Tran, Nuong Ai Nguyen Tran, Minh Quang Ngoc Ngo, Huong Thanh Thi Nguyen, Duy Khanh Tran, Thao Kieu Thi Le, Camelia Quek, Van Hung Pham, Son Truong Pham

“…Clinical data were gathered retrospectively from medical records, and additional details were provided by the patient’s family. …”
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P53 and Expression of Immunological Markers May Identify Early Stage Thyroid Tumors by Marjory Alana Marcello, Elaine Cristina Morari, Lucas Leite Cunha, Aline Carolina De Nadai Silva, Dirce Maria Carraro, André Lopes Carvalho, Fernando Augusto Soares, José Vassallo, Laura Sterian Ward

“…P53 expression was observed more frequently in malignant than in benign lesions (P<0.0001) and helped discriminate follicular patterned lesions. In addition, p53 was more frequent in smaller (P=0.0015), unique tumors (P=0.0286), with thyroiditis (P=0.0486) and without metastasis at diagnosis (P=0.0201). …”
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An In-depth Investigation of the Primordial Cluster Pair ASCC 19 and ASCC 21 by Qingshun Hu, Yuting Li, Mingfeng Qin, Chenglong Lv, Yang Pan, Yangping Luo, Shuo Ma

“…Their members with RVs exceeding 100 km s ^−1 are young variables. Additionally, a tidal interaction between the clusters is observed. …”
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Assessing Vegetation Canopy Growth Variations in Northeast China by Lijie Lu, Lingxue Yu, Xuan Li, Li Gao, Lun Bao, Xinyue Chang, Xiaohong Gao, Zhongquan Cai

“…Notably, the transition timing varied among different vegetation types, with grasslands (June) occurring earlier than forests (July) and farmlands (August). Additionally, grassland canopy growth showed a stronger response to precipitation than forests and farmlands, with a lagged effect of 2.50 months. …”
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16-Channel Hybrid WDM-PDM-MDM (de) Multiplexer for Multi-Band Large-Capacity Optical Transmission System Based on Thick Si<inline-formula><tex-math notation="LaTeX">$_{3}$</tex-mat... by Deyue Ma, Xiwen He, Chen Zhou, Mingyue Xiao, Jiqiao Liu, Weibiao Chen, Zhiping Zhou

“…Our results demonstrate that all channels of the (de)multiplexer have an average insertion loss of less than &#x2212;1.1 dB. In addition, the crosstalk in the same band is less than &#x2212;20 dB, while less than &#x2212;15 dB in different frequency bands. …”
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Native Italian poultry products: the factors influencing consumer perceptions by Eleonora Erika Cappone, Valeria Zambotto, Jatziri Mota-Gutierrez, Dominga Soglia, Giulia Maria Daniele, Marta Cianciabella, Andrea Pieroni, Renata Soukand, Mauro Penasa, Arianna Buccioni, Margherita Marzoni, Nicolaia Iaffaldano, Cesare Castellini, Silvia Cerolini, Claudio Forte, Achille Schiavone

“…This study aimed to predict the key factors influencing consumer perceptions of the quality traits of products from native poultry breeds and their willingness to pay for them. In addition, consumer preferences for native chicken meat and eggs were compared with those from commercial lines. …”
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Deriving Human Intestinal Organoids with Functional Tissue-Resident Macrophages All From Pluripotent Stem CellsSummary by Kentaro Tominaga, Daniel O. Kechele, J. Guillermo Sanchez, Simon Vales, Ingrid Jurickova, Lizza Roman, Akihiro Asai, Jacob R. Enriquez, Heather A. McCauley, Keishi Kishimoto, Kentaro Iwasawa, Akaljot Singh, Yuko Horio, Jorge O. Múnera, Takanori Takebe, Aaron M. Zorn, Michael A. Helmrath, Lee A. Denson, James M. Wells

“…Following 2 weeks of coculture, the organoids were used for transcriptional profiling, functional analysis of macrophages, or transplanted into immunocompromised mice and matured in vivo for an additional 10–12 weeks. Results: Macrophages were incorporated into developing HIOs and persisted for 2 weeks in vitro HIOs and for at least 12 weeks in HIOs in vivo. …”
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A Novel Therapeutic Calcium Peroxide Loaded Injectable Bio-adhesive Hydrogel Against Periodontitis by Shaojie Dong, Yukun Mei, Yuwei Zhang, Wenqing Bu, Yifei Zhang, Changjie Sun, Rui Zou, Lin Niu

“…By continuously releasing drugs in the periodontal pocket, the CP-P hydrogel effectively inhibited bacteria and reduce local inflammation response. In addition to bacteriostatic effects, the CP-P hydrogel also promoted the expression of osteogenic genes and enhanced osteogenic differentiation of PDLSCs in vitro. …”
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Ecological drivers of evolution of swine influenza in the United States: a review by Varun Goel, Jessica Ding, Bijaya Hatuwal, Emily Giri, Thomas J. Deliberto, James Lowe, Richard Webby, Michael Emch, Xiu-Feng Wan

“…The findings reveal that ecological factors at multiple spatial scales, such as regional transportation networks, interconnectedness of swine operations, farm environments, and presence of high-density, low-genetic diversity herds, can facilitate virus transmission and enhance virus evolution. Additionally, interactions at various interfaces, such as between commercial swine and feral swine, humans, or wild birds contribute to the increase in genetic diversity of swine IAVs. …”
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A Liquid Chromatography with Tandem Mass Spectrometry-Based Proteomic Analysis of Primary Cultured Cells and Subcultured Cells Using Mouse Adipose-Derived Mesenchymal Stem Cells by Yoshiki Nakashima, Saifun Nahar, Chika Miyagi-Shiohira, Takao Kinjo, Naoya Kobayashi, Issei Saitoh, Masami Watanabe, Jiro Fujita, Hirofumi Noguchi

“…However, seven proteins of growth were identified (Csf1, App, Adam15, Alcam, Tbl1xr1, Ninj1, and Sbds) in P0. In addition, four proteins of antioxidant activity were also identified (Srxn1, Txndc17, Fam213b, and Apoe) in P0. …”
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Nano‐silicon fertiliser increases the yield and quality of cherry radish by Xinxin Xu, Yaozu Guo, Yi Hao, Zeyu Cai, Yini Cao, Wanzhen Fang, Bangyin Zhao, Christy L. Haynes, Jason C. White, Chuanxin Ma

“…The nutritional content of the edible tissue was significantly enhanced, with an increase of 23.7% in reducing sugar, 24.8% in total sugar, and 232.7% in proteins; in addition, a number of nutritional elements (Cu, Mn, Fe, Zn, K, Ca, and P) were increased. …”
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Shrubs alter microbial community dynamics across various soil depths in alpine grassland ecosystems on the eastern Tibetan Plateau by Jingwei Chen, Qi Feng, Xiangtai Wang, Hang An, Jiahao Cao

“…However, the complexity of microbial networks among different soil depths under shrubs did not significantly differ, unlike in the control grassland. …”
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Transplacental and genotoxicity effects of thallium(I) during organogenesis in mice by Lucila Álvarez-Barrera, Rodrigo Aníbal Mateos-Nava, Keyla Nahomi Hernández-Córdova, Eduardo Lezama-Sánchez, Víctor Alan Alcántara-Mejía, Juan José Rodríguez-Mercado

“…Additionally, samples were taken from fetuses from pregnant mice treated with 5.28 and 6.16 mg/kg body weight to evaluate the transplacental genotoxicity. …”
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Through-wall Human Pose Reconstruction and Action Recognition Using Four-dimensional Imaging Radar by Rui ZHANG, Hanqin GONG, Ruiyuan SONG, Yadong LI, Zhi LU, Dongheng ZHANG, Yang HU, Yan CHEN

“…By preserving 3D spatial information and using long-sequence temporal information, the proposed ST2W-AP network considerably enhances the pose estimation and behavior recognition performance. Additionally, to address the influence of walls on signal quality, this paper introduces a deep echo domain compensator that leverages the powerful fitting performance and parallel output characteristics of deep learning, thereby reducing the computational overhead of traditional wall compensation methods. …”
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Adenosine cyclic phosphate with ultrasonic-assisted pectinase extraction alleviated allergic reactions in RBL-2H3 through inhibiting the influx of intracellular Ca2+ by Qiao Bai, Xiaoping Feng, Yu Wang, Chunyu Wu, Ye Liu, Jiao Sun, Tianli Yue, Fangyu Long

“…The level of anti-inflammatory factor interleukin-10 (IL-10) was promoted and the content of pro-inflammatory factor tumor necrosis factor-α (TNF-α) was suppressed by cAMP. In addition, influx of intracellular Ca2+ was repressed effectively. …”
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