Transcript Profiles of Stria Vascularis in Models of Waardenburg Syndrome by Linjun Chen, Lin Wang, Lei Chen, Fangyuan Wang, Fei Ji, Wei Sun, Hui Zhao, Weiju Han, Shiming Yang

“…There were 113 genes in tyrosine metabolism, melanin formation, and ion transportations showed significant changes in pig models and 191 genes in mice models. In addition, there were some spice’s specific gene changes in the stria vascularis in the mouse and porcine models. …”
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Vision Loss and Recovery after Baerveldt Aqueous Tube Shunt Implantation by Esther Lee Kim, Jeffrey Tran, Marc Töteberg-Harms, Jasdeep Chahal, Douglas Rhee, Vikas Chopra, Brian Francis

“…On multivariate analysis, poorer Snellen VA on postoperative day 1 (POD1) was found to be a significant risk factor for long-term vision loss (p=0.005). In addition, the negative change in preoperative versus POD1 Snellen VA (p=0.021) and the presence of split fixation involving the inferonasal quadrant on preoperative Humphrey visual field (p=0.044) were significant risk factors for snuff-out. …”
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Leptomeningeal Dissemination in Choroid Plexus Tumors: Magnetic Resonance Imaging Appearance and Risk Factors by Daniel Nunes do Espirito Santo, Monika Warmuth-Metz, Camelia-Maria Monoranu, Martin Hasselblatt, Christian Thomas, Torsten Pietsch, Jürgen Krauß, Tilmann Schweitzer, Brigitte Bison, Matthias Eyrich, Uwe Kordes, Denise Obrecht-Sturm, Mirko Pham, Annika Quenzer

“…Methods: We analyzed the imaging characteristics of LMD in a single-center pediatric cohort of 22 CPT patients (thirteen choroid plexus papilloma (CPP), six atypical choroid plexus papilloma (aCPP), three CPC), comparing LMD features with those of the primary tumor. Additionally, we examined the correlation between resection status and LMD development during follow-up. …”
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Achieving high strength, plasticity and conductivity in Cu/Cu-graphene oxide laminated composites with extremely low content of graphene oxide by Yan Zhao, Jiajing Liu, Yubo Zhang, Xin Sun, Wei Wang, Tingju Li

“…The yield strength (YS), ultimate tensile strength (UTS) and uniform elongation of the Cu/Cu-0.3GO-1 laminated composite are up to 377 MPa, 469 MPa and 22.0 %, respectively, with a very low mass fraction of 0.03 % GO. In addition, a nacre-like structure with the oriented arrangement of GO is obtained in Cu-0.3GO layers, which is conductive to carrier transport and leads to a high conductivity of 98.49 %IACS for laminated composites. …”
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Harnessing Non-Antibiotic Strategies to Counter Multidrug-Resistant Clinical Pathogens with Special Reference to Antimicrobial Peptides and Their Coatings by Shyam Kumar Mishra, Tanzina Akter, Umme Laila Urmi, George Enninful, Manjulatha Sara, Jiawei Shen, Dittu Suresh, Liangjun Zheng, Elias Shiferaw Mekonen, Binod Rayamajhee, Francesco M. Labricciosa, Massimo Sartelli, Mark Willcox

“…However, advancements in peptide engineering and chemical modifications offer solutions to enhance their clinical utility. Additionally, this review presents updates on strategies aimed at improving the cost, stability and selective toxicity of AMPs through the development of peptidomimetics. …”
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Performing whole-genome association analysis of winter wheat plant height using the 55K chip by Yindeng Ding, Guiqiang Fan, Yonghong Gao, Tianrong Huang, Anding Zhou, Shan Yu, Lianjia Zhao, Xiaolei Shi, Sunlei Ding, Jiahao Hao, Wei Wang, Jikun Song, Na Sun, Hui Fang

“…The results revealed significant phenotypic variation in wheat plant height across different years, with coefficients of variation ranging from 0.96% to 1.97%. Additionally, there was a strong correlation in plant height measurements between different years. …”
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Use of Hybrid Flame Retardants in Chemically Foamed rPET Blends by Veronika Anna Szabó, Sándor Kálmán Jakab, András Kovács, Tamara Zsuzsanna Böcz, Gábor Dogossy

“…The sample made with 15 phr OP and 5 phr MPP displayed outstanding performance, where five samples were capable of self-extinguishing in 5 s, while only slightly decreasing the tensile and flexural strength properties and simultaneously increasing the Young and flexural modulus compared to the reference sample. The addition of MPP reduced the porosity in many cases, while preventing cell coalescence. …”
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Therapeutic effect of low-dose BMSCs-Loaded 3D microscaffold on early osteonecrosis of the femoral head by Minzheng Guo, Baochuang Qi, Zijie Pei, Haonan Ni, Junxiao Ren, Huan Luo, Hongxin Shi, Chen Meng, Yang Yu, Zhifang Tang, Yongqing Xu, Qingyun Xue, Chuan Li

“…To understand the mechanism of efficacy, we established a co-culture model of human osteoblasts and BMSCs, followed by cell proliferation and activity detection, flow cytometry analysis, Quantitative RT-PCR, and Western blotting. Additionally, RNA sequencing was performed on femoral head tissues. …”
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Vegetation runoff and sediment reduction benefits and influential factor in the Loess Plateau of China: A meta-analysis by Mengrou Jia, Cong Han, Jianzhi Niu, Miao Wang, Linus Zhang, Ronny Berndtsson

“…However, vegetation restoration should account for regional environment and require species suited to local conditions. Additionally, maintaining plantations regularly throughout the vegetation lifecycle is essential to achieve long-term sustainable results.…”
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Prevalence and Risk Factors of Asymptomatic Colorectal Polyps in Taiwan by Fu-Wei Wang, Ping-I Hsu, Hung-Yi Chuang, Ming-Shium Tu, Guang-Yuan Mar, Tai-Ming King, Jui-Ho Wang, Chao-Wen Hsu, Chiu-Hua Chang, Hui-Chun Chen

“…Old age and alcohol consumption are additional risk factors for the development of adenomatous polyps.…”
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Targeting natural antioxidant polyphenols to protect neuroinflammation and neurodegenerative diseases: a comprehensive review by Maroua Jalouli, Md Ataur Rahman, Partha Biswas, Hasanur Rahman, Abdel Halim Harrath, In-Seon Lee, In-Seon Lee, Sojin Kang, Jinwon Choi, Moon Nyeo Park, Bonglee Kim, Bonglee Kim

“…Furthermore, polyphenols have demonstrated their therapeutic potential through the regulation of key signaling pathways such as Akt, Nrf2, STAT, and MAPK, which play critical roles in neuroprotection and the body’s immune response. This review emphasizes the growing body of evidence supporting the therapeutic potential of polyphenols in combating neurodegeneration and neuroinflammation, as well as enhancing brain health. …”
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Incorporation of κ-carrageenan improves the practical features of agar/konjac glucomannan/κ-carrageenan ternary system by Dongling Qiao, Hao Li, Fatang Jiang, Siming Zhao, Sheng Chen, Binjia Zhang

“…Three materials (agar, konjac glucomannan (KGM) and κ-carrageenan) were used to prepare ternary systems, i.e., sol-gels and their dried composites conditioned at varied relative humidity (RH) (33 %, 54 % and 75 %). …”
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Analysis of partial discharges in supporting insulators by D. A. Polyakov, K. I. Nikitin, N. A. Tereshchenko, A. S. Novoselov, Ya. P. Bilevich

“…Therefore, this method cannot be recommended for the diagnosis of supporting insulators before the disconnector is used by personnel, which could reduce the electrical injuries of personnel. In addition, monitoring of partial discharges also will not be effective for the studied types of defects.…”
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Different Flooding Conditions Affected Microbial Diversity in Riparian Zone of Huihe Wetland by Bademu Qiqige, Jingjing Liu, Ming Li, Xiaosheng Hu, Weiwei Guo, Ping Wang, Yi Ding, Qiuying Zhi, Yuxuan Wu, Xiao Guan, Junsheng Li

“…This study investigated the effects of wetted state (WS); wetting–drying state (WDS); and dried state (DS) on the diversity of soil bacteria, fungi, and archaea. …”
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Factors associated with hypercholesterolemia in older adults: A cross‐sectional investigation by Maria Clara Alves deOliveira, Júlia Perfeito Andrade, Ana Carolina Souza Porto, Gizelly Maria Torres Martins, Nurielly Monteiro Campos, Paulo daFonseca Valença Neto, Claudio Bispo De Almeida, Saulo Sacramento Meira, Beatriz Cardoso Roriz, Débora Jesus daSilva, Victor Giovannino Accetta, Cezar Augusto Casotti, Lucas dosSantos

“…Results The observed prevalence of hypercholesterolemia was 34.50% (men: 21.90%; women: 43.40%). Additionally, a higher probability of hypercholesterolemia was observed in women (PR: 1.94; 95% CI: 1.27–2.97); participants with high sedentary behavior (PR: 1.47; 95% CI: 1.03–2.09); those with abdominal obesity (PR: 1.65; 95% CI: 1.06–2.57); and those with diabetes mellitus (PR: 1.54; 95% CI: 1.04–2.29). …”
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Design and optimization of liquid helium-free cooling systems for magnetic resonance imaging device using multi-physical modeling by Changhao Luo, Guanhua Liu, Yi Deng, Zhiqiang Long, Meng Lin

“…An optimal flow velocity of 20 m/s was determined, balancing cooling efficiency with manageable pressure drops. Additionally, using copper foam with lower porosity and larger particle diameter further improved system performance, achieving cool-down times of 164 h for nitrogen and 58 h for helium, with pressure drops of 1.48 kPa and 1.49 kPa, respectively. …”
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Pre-injection of exosomes can significantly suppress ovarian cancer growth by activating the immune system in mice by Yuanyuan Wang, Changyi Zhang, Huimin Zeng, Liangliang Wang, Zanhong Wang, Zhiqiang Han

“…This increase was accompanied by a significant enhancement in granzyme B levels within CD8 + T cells. Additionally, there was a notable elevation in the concentration of interferon-gamma (IFN-γ) in peripheral blood. …”
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Effects of Novaluron Exposure on the Oviposition and Expression of Ovarian Development Related Genes in Silkworm, <i>Bombyx mori</i> (Lepidoptera: Bombycidae) by Meng-Jiao Wang, En-Xi Chen, Yi-Lin Ji, Yi-Xuan Qian, Yu-Ming Zhang, Lin Zhu, Guo-Dong Zhao, He-Ying Qian

“…Furthermore, novaluron exposure could affect the development of ovary tissue by reducing the number of oocytes and oogonia in the ovaries of silkworms fed with novaluron. In addition, the transcription levels of genes related to ovary development (<i>Vg</i>, <i>Ovo</i>, <i>Otu</i>, <i>Sxl-S</i> and <i>Sxl-L</i>) and hormone regulation (<i>EcR</i> and <i>JHBP</i>2) showed varying degrees of downregulation at 24 h, 48 h, and 72 h after novaluron treatment (<i>p</i> ≤ 0.05). …”
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Lonicera caerulea polyphenols inhibit fat absorption by regulating Nrf2-ARE pathway mediated epithelial barrier dysfunction and special microbiota by Yuehua Wang, Ningxuan Gao, Andrea Nieto-Veloza, Lingxi Zhou, Xiyun Sun, Xu Si, Jinlong Tian, Yang Lin, Xinyao Jiao, Bin Li

“…LCP also inhibited the dysfunction of the small intestine epithelial barrier, via alleviating the oxidative stress activated by Nrf2-ARE pathway, and by modulating the expressions of pro-inflammatory factors such as tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), cyclooxygenase-2 (COX-2), nuclear factor kappa-B p65 (NF-κB p65) and inducible nitric oxide synthase (iNOS) in the small intestine. Additionally, LCP administration restored the balance in small intestine microbiota and increased the abundance of the specific bacteria, such as Lactobacillus, involved in fat absorption. …”
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New formyl indole derivatives based on thiobarbituric acid and their nano-formulations; synthesis, characterization, parasitology and histopathology investigations by Walaa Ali Abdelhalim, Ahmed R. Rabee, Saied M. Soliman, Mohamed Hagar, Esraa A. Moneer, Basant A. Bakr, Assem Barakat, Matti Haukka, Hanaa A. Rasheed

“…The structures of the synthesized compounds were confirmed based on their spectral data via FT-IR, 1H and 13C NMR spectral characterization. In addition, the structure of 3a is confirmed using X-ray crystallography. …”
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