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58261
Exploring the prognostic significance of lactate-mitochondria-related genes in prostate cancer
Published 2025-01-01“…More importantly, MPO significantly inhibited PCa cell migration, invasion, and epithelial–mesenchymal transition (EMT), indicating its potential as an anticancer gene. Additionally, PCa with high MPO expression is highly sensitive to chemotherapeutic agents and mitochondrial inhibitors, highlighting its potential as an improved therapeutic strategy for PCa management.…”
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58262
Exploring the possible two-proton radioactivity of 38,39Ti
Published 2025-02-01“…Additionally, our analysis indicates a propensity for pairing between the valence protons in 39Ti. …”
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58263
Gradient diffusion entropy corrected ALNS optimization for vegetation topology interaction networks
Published 2025-01-01“…In this study, two characteristics of the vegetation interaction network constructed through density analysis linking land cover and land class transfer space can realize the objectivity of ecosystem simulation: (1) Constructing relationships between vegetation types using spaces where transfer patterns occur as aggregated clusters. (2) Calculation of relationship strength based on density analysis. In addition the interaction topology network was optimized using the gradient diffusion entropy correction ALNS to further enhance the stability of the proposed ecological interaction network structure. …”
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58264
An Environmentally Adaptive CRO-SL Algorithm Based on Dynamic Agents for the Channel Assignment Problem in Wireless Networks
Published 2025-01-01“…An exhaustive comparative analysis of four configurations of the proposed EnvAdapt-CRO-SL variant assesses the impact of each environmental agent on the algorithm’s performance. Additionally, external benchmarks against four different metaheuristics, along with an analysis of the influence of pseudorandom number generators on initialization and search operators, and a robust optimization case study, provide deeper insights. …”
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58265
Characterization of the Different Chemical Components and Nutritional Properties of Two <i>Eryngium</i> Species
Published 2025-01-01“…These findings highlight the nutritional value of <i>Eryngium</i> species as a functional ingredient in the food industry. Additionally, their antioxidant properties suggest promising uses in pharmaceutical applications.…”
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58266
Combined Aerobic and Resistance Exercises Evokes Longer Reductions on Ambulatory Blood Pressure in Resistant Hypertension: A Randomized Crossover Trial
Published 2020-01-01“…Notably, longer hypotension periods were observed after COM exercise. In addition, NON-RH and RH people showed different changes on BP after exercise sessions, suggesting that postexercise hypotension is influenced by the pathophysiological bases of hypertension.…”
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58267
Potential Involvement of IL-17F in Asthma
Published 2014-01-01“…IL-17F-induced CCL20 may attract Th17 cells into the airway resulting in the recruitment of additional Th17 cells to enhance allergic airway inflammation. …”
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58268
A Pilot Analysis of Patient Portal Use and Breast Cancer Screening Among Black Patients in a Large Academic Health System
Published 2025-02-01“…The authors estimated average marginal effects to examine the additive probability of breast cancer screening completion given portal use in the prior 12 months. …”
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58269
Genome-Wide Approach Identifies Natural Large-Fragment Deletion in ASFV Strains Circulating in Italy During 2023
Published 2025-01-01“…In this study, ASFV strains collected in Italy during 2022–2023 from two geographical clusters, North-West (Alessandria) and Calabria, were fully sequenced. In addition, an in vivo experiment in pigs was performed. …”
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58270
The extraction of effective components and an antioxidant activity study of Tulipa edulis
Published 2024-01-01“…Plant extracts from natural sources are an excellent choice for food additives and natural antioxidants. In this study, the active components of Tulipa edulis were extracted and analysed, and their antioxidant capacity was measured. …”
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58271
Patient Complications after Interscalene Block: A Retrospective Comparison of Liposomal Bupivacaine to Nonliposomal Bupivacaine
Published 2020-01-01“…Patients were divided into two groups those who did receive liposome bupivacaine in their ISB and those who did not receive liposome bupivacaine in their ISB. …”
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58272
IL-17 Is a Key Regulator of Mucin-Galectin-3 Interactions in Asthma
Published 2021-01-01“…We previously showed that the absence of tissue inhibitor of metalloproteinase 1 (TIMP-1) enhances lung inflammation, airway hyperreactivity, and lung remodeling in asthma in an ovalbumin (OVA) asthma model of TIMP-1 knockout (TIMPKO) mice as compared to wild-type (WT) controls and mediated by increased galectin-3 (Gal-3) levels. Additionally, we have shown that in the lung epithelial cell line A549, Gal-3 inhibition increases interleukin-17 (IL-17) levels, leading to increased mucin expression in the airway epithelium. …”
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58273
Evaluation of Navigated Laser Photocoagulation (Navilas 577+) for the Treatment of Refractory Diabetic Macular Edema
Published 2018-01-01“…After initial navigated laser treatment, 16 of 25 eyes (64%) were needed additional navigated laser photocoagulation, injection of triamcinolone acetonide, and/or injection of VEGF agents. …”
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58274
Toward Generality of a Framework for Quantifying Biomechanical Stability: Demonstration on the Ankle
Published 2025-01-01“…The expected trend for subsequent injury states was progressive instability, and the observed trends from experimental testing aligned with this prior expectation. However, additional work on the framework is necessary to make it truly generalized.…”
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58275
Digital connection, real bonding: Brief online chats boost interpersonal closeness regardless of the conversational topic
Published 2025-02-01“…Results indicated that participants in the interactive condition reported feeling significantly closer to their interlocutor than those in the non-interactive condition. In addition, greater perceived pleasantness, intimacy, and the importance of the other person's contribution to the conversation were associated with increased feelings of closeness. …”
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58276
Anti-inflammatory Property of Galectin-1 in a Murine Model of Allergic Airway Inflammation
Published 2019-01-01“…These immunomodulatory effects in the allergic lung were correlated with the activation of extracellular signal-regulated kinase (ERK) signaling pathway and downregulation of endogenous Gal-1. In addition, rGal-1 reduced the plasma concentrations of anti-OVA immunoglobulin E (IgE) and IL-17. …”
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58277
Impacts of hyperthermic chemotherapeutic agent on cytotoxicity, chemoresistance-related proteins and PD-L1 expression in human gastric cancer cells
Published 2024-12-01“…Furthermore, the combination of 5-Fu and hyperthermia reduces levels of both phosphorylated STAT3 and STAT3, while increasing the levels of phosphorylated Akt and ERK. In addition, 5-Fu/hyperthermia enhances reactive oxygen species and suppresses superoxide dismutase 1. …”
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58278
Staphylococcus aureus carriage is associated with microbiome composition in the nares and oropharynx, not the hand, of monozygotic twins
Published 2025-01-01“…., the nares, oropharynx, and hand microbiomes, using 16S rRNA v3-v4 sequencing in addition to S. aureus carriage status. The prevalence of S. aureus was highest in the oropharynx followed by nares and hand with concordance between twin pairs highest in the nares, followed by oropharynx. …”
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58279
Resolving the electronic ground state of La3Ni2O7-δ films
Published 2025-02-01“…Through X-ray absorption spectroscopy, we reveal the influence of oxygen ligands on the electronic ground states of the Ni ions, displaying a charge transfer nature akin to cuprate but with distinct orbital configurations. Additionally, in La3Ni2O7-δ films, we detect a superlattice reflection (1/4, 1/4, L) at the Ni L absorption edge using resonant X-ray scattering measurements. …”
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58280
Stabilization effect and mechanism of heavy metals by microbial consortium of phosphate-solubilizing bacteria and urease-producing bacteria
Published 2025-02-01“…An in-depth analysis showed that the composite metals were precipitated as dense precipitate encased in carbonate and phosphate, and additionally could be stabilized in the form of biosorption. …”
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