Nanocomplex hyaluronic acid/ganciclovir@ZIF-8 for ganciclovir efficient delivery and targeted anti-KSHV treatment by Fangling Li, Chengjing Liu, Wenyi Gu, Qianhe Xu, Dongmei Li, Dongdong Cao, Zhiyong Liu

“…Exploiting the decomposition property of ZIF-8 under acidic conditions, the nanocomplex exhibits pH-responsive drug release in slightly acidic tumor environment. In addition, HA/GCV@ZIF-8 not only suppresses expression of KSHV pathogenic genes with less drug dose, but also inhibits the ability of cell proliferation and migration. …”
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In the coevolution of cotton and pathogenic fungi, resistant cotton varieties lead to an escalation in the virulence of Verticillium dahliae by Yalin Zhang, Lifang Cui, Ruibing Liu, Zili Feng, Hongjie Feng, Jinglong Zhou, Lihong Zhao, Feng Wei, Heqin Zhu

“…Pathogenicity assays demonstrated that the virulence of the offspring strains triggered by continuous induction of disease-resistant cotton cultivar increased from the 4th generation and reached its peak by the 6th generation. Additionally, the transcriptome analysis revealed that the 4th and 6th generations of strains differentially expressed genes (DEGs) accumulated a significant number of response genes associated with pathogen pathogenicity differentiation, including the mitogen-activated protein kinase (MAPK) signaling pathway, amino and antibiotic biosynthesis, phenylpropanoid metabolism. …”
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Prevalence of behavioral risk factors among Ukrainians during war amid existing stress factors by Olena Kolesnikova, Olena Vysotska, Anastasiia Radchenko, Olga Zaprovalna, Nataliya Emelyanova

“…Dietary issues were reported by 34.7%, with 22.4% experiencing weight gain and 36.2% reporting weight loss. In addition, 13.3% and 16.8% indicated increased smoking and alcohol consumption, respectively. …”
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Stability of lead immobilization by Aspergillus niger and fluorapatite under different pH conditions by Baoxin Feng, Yu Xue, Dechao Wang, Shenghao Chen, Shuo Zhang, Liangliang Zhang, Xiaohui Chen, Da Tian, Xinxin Ye

“…The strong acidic conditions (pH 1.5) inhibited the growth of A. niger and caused a lower Pb removal ratio of 37.86 %. In addition, the formed minerals of lead oxalate and lead/calcium oxalate coprecipitate dominate the Pb remediation by A. niger and FAp. …”
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Comparative Approach to Define Increased Regulatory T Cells in Different Cancer Subtypes by Combined Assessment of CD127 and FOXP3 by Marc Beyer, Sabine Classen, Elmar Endl, Matthias Kochanek, Martin R. Weihrauch, Svenja Debey-Pascher, Percy A. Knolle, Joachim L. Schultze

“…In healthy individuals, low-level expression of CD127 on T cells in addition to the expression of FOXP3 has been associated with Treg cells. …”
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Therapeutic effects of acupuncture therapy for kidney function and common symptoms in patients with chronic kidney disease: a systematic review and meta-analysis by Shan Liu, Fan Zhang, Yan Bai, Liuyan Huang, Yifei Zhong, Yi Li

“…Compared to the control group, acupuncture therapy reduced serum creatinine levels (standardized mean difference [SMD]: −0.57; 95% CI −1.05 to −0.09) and relieved pruritus (SMD: −2.20; 95% CI −3.84, −0.57) in patients with CKD, while the TSA showed that the included sample size did not exceed the required information size. The included studies did not report acupuncture-related adverse events.Conclusions Acupuncture is an effective and safe treatment for improving kidney function and relieving pruritic symptoms in patients with CKD, but the very low evidence may limit this conclusion. …”
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Automatic Roadway Backfilling of Caving Gangue for Cutting Roofs by Combined Support on Gob-Side Entry Retaining with No-Pillars: A Case Study by Shengrong Xie, Xiaoyu Wu, Dongdong Chen, Yaohui Sun, Junchao Zeng, Qing Zhang, Chunwei Ji, Qiong Cheng, En Wang, Yuxin Ren

“…The numerical simulation is used to simulate and analyze the roof hanging and the roof cutting structures. In addition, a field engineering test is performed. The field test shows that automatic roadway technology for cutting roofs by combined support on gob-side entry retaining with no-pillars is feasible. …”
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Numerical assessment of solar panel with utilizing ferrofluid flow within wavy duct equipped with V-shaped fins by Mohammed A. Tashkandi, Ali Basem, Hussein A.Z. AL-bonsrulah, Lioua Kolsi, Mahmood Shaker Albdeiri, Lotfi Ben Said, Amira M. Hussin

“…When the Hartmann number is set to 95, an increase in dust levels leads to a reduction of 25.33 % in ηPV and 9.82 % in ηth. Additionally, the work finds that the impact of the (ϕ) on both ηPV and ηth is significantly greater at a higher inlet velocity (Vin = 0.093), being 3.96 and 2.7 times greater, respectively, compared to a lower velocity (Vin = 0.018).…”
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Risk Factors for Mortality in Melioidosis: A Single-Centre, 10-Year Retrospective Cohort Study by Raviraj Menon, Poornima Baby, Anil Kumar V., Sandeep Surendran, Manu Pradeep, Aiswarya Rajendran, Gaayathri Suju, Arathy Ashok

“…Logistic regression analysis was performed to screen mortality risk factors of melioidosis in addition to descriptive statistics and chi-square analysis. …”
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Drag‐Based CME Modeling With Heliospheric Images Incorporating Frontal Deformation: ELEvoHI 2.0 by Jürgen Hinterreiter, Tanja Amerstorfer, Manuela Temmer, Martin A. Reiss, Andreas J. Weiss, Christian Möstl, Luke A. Barnard, Jens Pomoell, Maike Bauer, Ute V. Amerstorfer

“…The evolution of the CME front, especially at the flanks, is highly dependent on the ambient solar wind model used. An additional advantage of the new implementation is given by the possibility to provide estimates of the CME mass.…”
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Combined effects of global DNA methylation, blood lead and total urinary arsenic levels on developmental delay in preschool children by Yuu-Hueih Hsu, Chih-Yin Wu, Hui-Ling Lee, Ru-Lan Hsieh, Ya-Li Huang, Horng-Sheng Shiue, Ying-Chin Lin, Mei-Chieh Chen, Yu-Mei Hsueh

“…Our research sought to investigate the correlation between 5mdC and developmental delay (DD) among preschoolers. Additionally, we assessed whether 5mdC modified the impacts of blood lead and total urinary arsenic levels on DD. …”
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Diabetic Macular Edema Treatment with Bevacizumab Does Not Depend on the Retinal Nonperfusion Presence by Bogumiła Sędziak-Marcinek, Sławomir Teper, Elżbieta Chełmecka, Adam Wylęgała, Mateusz Marcinek, Mateusz Bas, Edward Wylęgała

“…The results show that bevacizumab reduced the macular CST from 420 to 280 μm (p<0.001) and improved BCVA (p<0.001) by about 10 ETDRS letters in both groups of patients. Additionally, the therapy reduced total retinal NPA from 29 (14-36) mm2 to 12 (4-18) mm2 (Me (Q1-Q3); p<0.001) in patients with diagnosed nonperfusion. …”
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Dissemination through trusted credible messengers: 133 weeks of the Flint Community Webinar on COVID-19 by Heatherlun Uphold, E. Yvonne Lewis, Amy Drahota, Blair Warren, Jennifer Edwards-Johnson, Mary Katherine Crawford, Richard Sadler, Susan J. Woolford, Roni Ellington, Marc Zimmerman, Alison Grodzinski, C. Debra Furr-Holden

“…Results The webinar reached a minimum of 877 unique within-webinar participants, representing more than 9,190 in-webinar participant hours and an additional 17,303 YouTube views. A consistent base of weekly attendees (e.g., service providers, community members) reported increasing levels of satisfaction and utility over time. …”
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Enhancing Mars Gravity Field Solutions with China’s Tianwen-1 Tracking Data by Shangbiao Sun, Jianguo Yan, Shanhong Liu, Chongyang Wang, Denggao Qiu, Jean-Pierre Barriot

“…The range of gravity anomaly errors improves after incorporating TW1 data, with the maximum error decreasing from 53.4 to 46.4 mGal and the average error improving from 8.4 to 7.3 mGal. Additionally, orbit determination experiments confirm that the fused gravity field model enhances trajectory modeling for both MRO and TW1. …”
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Partial rejuvenation of the spermatogonial stem cell niche after gender-affirming hormone therapy in trans women by Emily Delgouffe, Samuel Madureira Silva, Frédéric Chalmel, Wilfried Cools, Camille Raets, Kelly Tilleman, Guy T'Sjoen, Yoni Baert, Ellen Goossens

“…The transcriptomic profile of transgender tissue confirmed a loss of mature characteristics - a partial rejuvenation - of the spermatogonial stem cell niche and, in addition, detected inflammation processes occurring in the samples. …”
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Arterial Hypertension and Interleukins: Potential Therapeutic Target or Future Diagnostic Marker? by Daniela Maria Tanase, Evelina Maria Gosav, Smaranda Radu, Anca Ouatu, Ciprian Rezus, Manuela Ciocoiu, Claudia Florida Costea, Mariana Floria

“…As such, conventional cardiovascular drugs (statins, calcium channels blockers, and ACEIs/ARBs) have shown additional anti-inflammatory effects that could be linked to their blood pressure lowering properties. …”
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Towards the Sustainable Removal of Heavy Metals from Wastewater Using <i>Arthrospira platensis</i>: A Laboratory-Scale Approach in the Context of a Green Circular Economy by Lamprini Malletzidou, Eleni Kyratzopoulou, Nikoletta Kyzaki, Evangelos Nerantzis, Nikolaos A. Kazakis

“…The heavy metal removal efficiency of <i>A. platensis</i> cultures was evaluated using atomic absorption spectroscopy (AAS). Additionally, the cultures were examined using Fourier transform infrared (FTIR) spectroscopy, Near-Infrared (NIR) Spectroscopy, UV-Vis spectrophotometry, and optical microscopy, together with pH and electrical conductivity (EC) measurements to evaluate the quality of the cultures and the changes induced by heavy metal stress. …”
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ZnO Nanoparticles by Hydrothermal Method: Synthesis and Characterization by Juan Carlos Anaya-Zavaleta, Antonio Serguei Ledezma-Pérez, Carlos Gallardo-Vega, Joelis Rodríguez-Hernández, Carmen Natividad Alvarado-Canché, Perla Elvia García-Casillas, Arxel de León, Agustín Leobardo Herrera-May

“…X-ray diffraction (XRD) confirmed high-crystalline quality, with crystallite sizes calculated using the Scherrer equation. In addition, the effective mass model provided an estimated band gap that matched with the reported data. …”
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Increased Expression of TLR10 in B Cell Subsets Correlates with Disease Activity in Rheumatoid Arthritis by Ying Zhang, Rong Cao, Haijian Ying, Juping Du, Shuaishuai Chen, Na Wang, Bo Shen

“…Compared to that in the HCs, TLR10 was elevated significantly in the CD19+CD27−IgD− and CD19+CD5+ subsets in the RA subjects. In addition, almost all subsets expressing TLR10 were increased with disease activity. …”
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Analytical methods for nanomaterials investigation in food and food-related materials by Daniele Passeri, Pierfrancesco Atanasio, Anacleto Proietti, Chiara Mancini, Flavio Cognigni, Giancarlo La Penna, Luca Buccini, Marco Rossi, Anna Chiara Turco, Marilena D'Amato, Angela Sorbo, Simone Dinarelli, Giulia D'Ettorre, Federica Aureli

“…All these improvements, however, need to be achieved in a ‘safe’ way, thus there is a wide and constantly updated legislation that deals with the possible toxicity of these additions by posing some limitation to the percentage of nanosized elements added and to their composition. …”
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