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58101
Modeling of Ultraviolet Aurora Intensity Associated With Interplanetary and Geomagnetic Parameters Based on Neural Networks
Published 2021-11-01“…Based on the respective training datasets of GRNN and CGAN models, the evaluating results showed that the mean values (standard deviation) of SSIM were 0.5409 (0.0912) and 0.5876 (0.0712), respectively, so the prediction results from both models can restore the auroral intensity distribution of the original images of UVI. In addition, the value of SSIM can increase with the increase of the number of training data. …”
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58102
The role of intrapartum ultrasound combined with free position delivery in the management of abnormal fetal positions during labor
Published 2025-01-01“…Furthermore, the rate of cesarean sections due to failed progression was significantly lower in the experimental group. Additionally, the experimental group experienced lower rates of postpartum hemorrhage and shorter hospital stays, with statistically significant differences observed. …”
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58103
A heteropolysaccharide from Rhodiola rosea L.: preparation, purification and anti-tumor activities in H22-bearing mice
Published 2023-03-01“…The results shown that RLP (100 and 300 mg/kg) could inhibit tumor growth of H22 cells from 23.59 % to 45.52 % and protect thymuses and spleen without damage. In addition, according to cell cycle, AV-FITC/PI and JC-1, RLP could induce dose-dependent apoptosis of H22 cells via S phase arrested which was through a mitochondrial related pathway. …”
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58104
Decoding nature: multi-target anti-inflammatory mechanisms of natural products in the TLR4/NF-κB pathway
Published 2025-01-01“…These discoveries are integrated into the classical TLR4/NF-κB pathway to systematically elucidate the latest mechanisms among various targets. Additionally, we summarize the pharmacological mechanisms by which natural products exert anti-inflammatory effects through the TLR4/NF-κB pathway. …”
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58105
Nonacademic predictors of China medical licensing examination
Published 2025-01-01“…Results We identified seven nonacademic predictors for GMKT performance. Body mass index (BMI) and working memory reaction time showed direct negative effects on GMKT performance. …”
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58106
Bronchotracheal Stenting Management by Rigid Bronchoscopy under Extracorporeal Membrane Oxygenation (ECMO) Support: 10 Years of Experience in a Tertiary Center
Published 2021-01-01“…Elective ECMO support was helpful and safe for the high-risk management of bronchotracheal stenting with rigid bronchoscopy and was not associated with any additional significant complications.…”
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58107
Influence of Anti-TNF and Disease Modifying Antirheumatic Drugs Therapy on Pulmonary Forced Vital Capacity Associated to Ankylosing Spondylitis: A 2-Year Follow-Up Observational St...
Published 2015-01-01“…This preliminary study supports the fact that anti-TNF agents may offer additional benefits compared to DMARDs in patients with AS who have reduced FVC%.…”
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58108
Analisis Kritik Terhadap Model Kipas; Konseling Intensif Progresif Adaptif Struktur
Published 2017-06-01“…Konseling Intensif Progresif Adaptif Struktur (KIPAS) yang dikreasikan oleh Andi Mappiare-AT muncul sebagai salah satu dari sedikit jenis bimbingan dan konseling yang berlandaskan pada budaya Nusantara. …”
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58109
Hydrogen-Rich Saline Attenuates Acute Renal Injury in Sodium Taurocholate-Induced Severe Acute Pancreatitis by Inhibiting ROS and NF-κB Pathway
Published 2015-01-01“…Results showed that hydrogen-rich saline attenuated the following: (1) serum Cr and BUN, (2) pancreatic and renal pathological injuries, (3) renal MDA, (4) renal MPO, (5) serum IL-1β, IL-6, and renal TNF-α, HMGB1, and (6) tyrosine nitration, IκB degradation, and NF-κB activation in renal tissues. In addition, it increased the level of IL-10 and SOD activity in renal tissues. …”
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58110
Macrophages overexpressing interleukin‐10 target and prevent atherosclerosis: Regression of plaque formation and reduction in necrotic core
Published 2025-01-01“…Moreover, there was a significant reduction in MMP9, a biomarker associated with plaque rupture, in IL‐10M‐treated plaques from both the early and late intervention groups. Additionally, the administration of IL‐10M showed no obvious side effects. …”
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58111
MicroRNA-132 Interact with p250GAP/Cdc42 Pathway in the Hippocampal Neuronal Culture Model of Acquired Epilepsy and Associated with Epileptogenesis Process
Published 2016-01-01“…Silencing miR-132 inhibited the electrical excitability level of cultured epileptic neurons, whereas silencing p250GAP had an opposite effect. In addition, we verified the effect of miR-132 in vivo and found that silencing miR-132 inhibited the aberrant formation of dendritic spines and chronic spontaneous seizure in a lithium-pilocarpine-induced epileptic mouse model. …”
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58112
Rapamycin Improves Palmitate-Induced ER Stress/NF κ B Pathways Associated with Stimulating Autophagy in Adipocytes
Published 2015-01-01“…Inhibiting autophagy with chloroquine (CQ) exacerbated these ER stress markers, indicating the role of autophagy in ameliorating ER stress. In addition, cotreatment of CQ abolished the anti-ER stress effects of rapamycin, which confirms the effect of rapamycin on ERs is autophagy-dependent. …”
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58113
Semaphorin 3A Inhibits Inflammation in Chondrocytes under Excessive Mechanical Stress
Published 2018-01-01“…Added Sema3A inhibited the gene expression of inflammatory cytokines upregulated by CTS in a dose-dependent manner. Addition of Sema3A suppressed the activation of AKT, ERK, and NF-κB in a dose-dependent manner. …”
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58114
A systematic review of Aspilia africana (Pers.) C.D. adams traditional medicinal uses, phytoconstituents, bioactivities, and toxicities
Published 2025-02-01“…However, the major components responsible for these bioactivities and their mechanisms of action in some diseases have not yet been clearly identified. Additionally, toxicity and clinical trial data for A. africana are limited with most toxicological assessments being acute in nature. …”
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58115
The role of ferroptosis in colorectal cancer and its potential synergy with immunotherapy
Published 2025-01-01“…Meanwhile, traditional Chinese medicine therapies promote antitumor immunity by modulating the TME and inducing ferroptosis. Additionally, advances in nanotechnology have facilitated precise therapy by enabling targeted delivery of ferroptosis inducers or immunomodulators, transforming “cold” tumors into “hot” tumors and further boosting ICI efficacy. …”
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58116
Efficacy of human umbilical cord mesenchymal stem cell in the treatment of neuromyelitis optica spectrum disorders: an animal study
Published 2025-02-01“…Then, disease progression, immune responses, and blood–brain barrier integrity were evaluated. Additionally, we tested the effects of hUC-MSCs on astrocyte viability and apoptosis using an aquaporin 4 (AQP4) IgG and complement-induced cytotoxicity model in vitro. …”
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58117
Cardiometabolic Risk in Hyperlipidemic Men and Women
Published 2016-01-01“…HL-women were older and had overall more favourable concentrations of lipid parameters and liver enzymes but did not differ regarding vascular morphology and insulin sensitivity compared to HL-men of comparable body mass index (BMI).…”
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58118
Proteome-Wide Identification and Comparison of Drug Pockets for Discovering New Drug Indications and Side Effects
Published 2025-01-01“…The results of a pairwise pocket similarity analysis identified 220,312 similar pocket pairs, with 3241 pairs across different protein families, indicating shared drug-binding potential. In addition, 62,077 significant matches were found between druggable pockets and 1872 known drug pockets, highlighting candidates for drug repositioning. …”
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58119
Pruritus Features in Children with End-Stage Renal Disease Underwent Dialysis: A Cross-Sectional Study
Published 2021-01-01“…In addition, an increase in age for one year was found to be associated with 50% higher odds of having total pruritus score≥5 (OR: 1.5; 95% CI 1.03 to 2.18). …”
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58120
Exploring Magnetic Fields in Molecular Clouds through Denoising Diffusion Probabilistic Models
Published 2025-01-01“…The 3-channel DDPM consistently outperformed both the other DDPM variants and the power-law fitting approach based on column density alone, demonstrating its robustness in handling previously unseen data. Additionally, we compared the performance of the Davis–Chandrasekhar–Fermi (DCF) methods, both classical and modified, to the DDPM predictions. …”
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