Synergistic Effects of FGF-18 and TGF-β3 on the Chondrogenesis of Human Adipose-Derived Mesenchymal Stem Cells in the Pellet Culture by Liangjie Huang, Lingxian Yi, Chunli Zhang, Ying He, Liangliang Zhou, Yan Liu, Long Qian, Shuxun Hou, Tujun Weng

“…Recently, fibroblast growth factor 18 (FGF-18) has gained marked attention due to its anabolic effects on cartilage metabolism, but existing data regarding the role of FGF-18 on the chondrogenic potential of mesenchymal stem cells (MSCs) are conflicting. In addition, whether the combined application of FGF-18 and TGF-β3 would improve the efficiency of the chondrogenic potential of ADSCs has not been thoroughly studied. …”
Get full text

Collagen Induced Arthritis in DBA/1J Mice Associates with Oxylipin Changes in Plasma by Min He, Eduard van Wijk, Ruud Berger, Mei Wang, Katrin Strassburg, Johannes C. Schoeman, Rob J. Vreeken, Herman van Wietmarschen, Amy C. Harms, Masaki Kobayashi, Thomas Hankemeier, Jan van der Greef

“…The results in univariate Student’s t-test revealed 10 significantly up- or downregulated oxylipins in CIA mice, which were supplemented by another 6 additional oxylipins, contributing to group clustering upon multivariate analysis. …”
Get full text

Induction of larval settlement and metamorphosis of Mercenaria mercenaria using excess Ca2＋and Mg2+alone or in combination by Jian Liang, Bajun Shi, Yongren Li, Shuang Liang, Huiru Liu, Wei Dai, Yongjun Guo

“…The supplementation of the above optimal concentration of ions from D-shaped larvae stage also significantly induced larval metamorphosis (P < 0.05), and at the same concentration, the induction effect was better than that initiating from pediveliger stage. In addition, compared with the control group, ion supplementation from D-shaped larvae stage significantly increased the survival rate of pediveligers (P < 0.05) and prolonged the planktonic duration. …”
Get full text

Effects of aluminum on metabolism of reactive oxygen species and reactive nitrogen species in root tips of different Eucalyptus species by Zilong Ouyang, Bing Liu, Tangkan Li, Tiandao Bai, Weichao Teng

“…The antioxidant enzymes activities of the root tips of different Eucalyptus species induced by Al stress resulted in different ROS and RNS contents, ultimately resulting in differing degrees of membrane lipid peroxidation. In addition to suppressions of root relative elongation and root activity, the accumulations of soluble sugar, soluble protein, and proline can be used as indicators of Al sensitivity in Eucalyptus species. …”
Get full text

Puerarin pretreatment provides protection against myocardial ischemia/reperfusion injury via inhibiting excessive autophagy and apoptosis by modulation of HES1 by Yong Yuan, Songqing Lai, Tie Hu, Fajia Hu, Chenchao Zou, Xiuqi Wang, Ming Fang, Jichun Liu, Huang Huang

“…The results demonstrated that Pue pretreatment effectively alleviated MIRI, as manifested by diminishing the levels of serum CK-MB and LDH, mitigating the extent of myocardial infarction and enhancing cardiac functionality. Additionally, Pue significantly alleviated histopathological damage in MIRI-treated myocardium, as evidenced by HE staining and TUNEL assay. …”
Get full text

Study on the Siting of Offshore Wind Farms and Prospects for Future Development by Zhichuan LI, Xinghua LI, Jingshui LAO, Zhiyou YU, Wei XU, Jianzhang SUN, Zijian ZHANG, Ya LI

“…With the maturity of shallow sea wind farm technology, the deep-sea offshore wind farm will be gradually developed in the future, which will further promote the development of floating offshore wind power. In addition, the cooperation development of offshore wind farms with oil and gas development, marine aquaculture and other projects will receive more research and attention.…”
Get full text

Hostility Modifies the Association between TV Viewing and Cardiometabolic Risk by Anthony Fabio, Chung-Yu Chen, Kevin H. Kim, Darin Erickson, David R. Jacobs, Janice C. Zgibor, Tammy Chung, Karen A. Matthews, Steven Sidney, Carlos Iribarren, Mark A. Pereira

“…Multiple group analysis of additional cross-lagged panel models stratified by high and low levels of hostility was used to evaluate whether the association was modified by the hostile personality trait. …”
Get full text

The Study of Viral RNA Diversity in Bird Samples Using De Novo Designed Multiplex Genus-Specific Primer Panels by Andrey A. Ayginin, Ekaterina V. Pimkina, Alina D. Matsvay, Anna S. Speranskaya, Marina V. Safonova, Ekaterina A. Blinova, Ilya V. Artyushin, Vladimir G. Dedkov, German A. Shipulin, Kamil Khafizov

“…Advances in the next generation sequencing (NGS) technologies have significantly increased our ability to detect new viral pathogens and systematically determine the spectrum of viruses prevalent in various biological samples. In addition, this approach has also helped in establishing the associations of viromes with many diseases. …”
Get full text

Post-COVID pain and quality of life in COVID-19 patients: protocol for a meta-analysis and systematic review by Yongxing Xu, Jianwen Gu, Mengrong Miao, Yitian Yang, Pule Li, Mengqi Jia, Zhaoyu Wen, Mengmeng Yu, Jiaqiang Zhang

“…Among these sequelae, pain symptoms should not be neglected. In addition, the sequelae of COVID-19 also decrease the quality of life of these populations. …”
Get full text

Mixture of Bacillus Amyloliquefaciens and Bacillus Pumilus Modulates Community Structures of Rice Rhizosphere Soil to Suppress Rice Seedling Blight by Jiang Nan, Qiu Jiehua, Tian Dagang, Shi Huanbin, Liu Zhiquan, Wen Hui, Xie Shuwei, Chen Huizhe, Wu Meng, Kou Yanjun

“…In this study, we isolated biocontrol bacteria from paddy fields that significantly inhibited the growth of F. oxysporum in vitro and identified the strains as Bacillus amyloliquefaciens T40 and Bacillus pumilus T208. …”
Get full text

Informatics strategies for early detection and risk mitigation in pancreatic cancer patients by Di Jin, Najeeb Ullah Khan, Wei Gu, Huijun Lei, Ajay Goel, Tianhui Chen

“…This review also explores the potential of novel biomarkers, including those found in body fluids, such as serum, plasma, urine, and bile, as well as the emerging role of liquid biopsy technologies in analyzing circulating tumor DNA (ctDNA), circulating tumor cells (CTCs), and exosomes. …”
Get full text

Anchored and epoxied ferrocement strips for improving flexural performance of two-way reinforced concrete slabs by Galal Elsamak, Mohamed Ghalla, Moataz Badawi, Abdullah Albogami, Taher A. Tawfik, Ramy I. Shahin

“…By replacing a portion of the slab's concrete cover with ferrocement strips, this method aims to enhance the load-carrying capacity, ductility, and crack resistance of the slabs while optimizing material usage and minimizing additional weight. Experimental results revealed that all strengthened specimens demonstrated improved ultimate load capacities compared to the control slab, with enhancements ranging from 12 % to 33 %. …”
Get full text

Olivetol’s Effects on Metabolic State and Gut Microbiota Functionality in Mouse Models of Alimentary Obesity, Diabetes Mellitus Type 1 and 2, and Hypercholesterolemia by Anastasia A. Zabolotneva, Katerina E. Popruga, Valentin V. Makarov, Sergei M. Yudin, Andrei M. Gaponov, Sergei A. Roumiantsev, Aleksandr V. Shestopalov

“…In addition, olivetol affected the composition and functional activity of gut microbiota communities, inducing an expansion of probiotic species such as <i>Akkermansia muciniphila</i> and <i>Bacteroides acidifaciens</i> and depleting the representation of pathobionts such as <i>Prevotella</i>, although olivetol supplementation did not influence the diversity or richness of the communities. …”
Get full text

Isolation of a Novel Caprine <i>Eimeria christenseni</i> Strain (GC) in Canary Islands and Analysis of Parasitological, Clinical, and Pathological Findings on Experimentally Infected Goat Kids by Emilio Barba, José Manuel Molina, Francisco Rodríguez, Otilia Ferrer, María Carmen Muñoz, Liliana M. R. Silva, María Cristina Del Río, José Adrián Molina, Anja Taubert, Carlos Hermosilla, Antonio Ruiz

“…Oocyst shedding, clinical signs, and production parameters, in addition to haematological and histopathological features, were monitored. …”
Get full text

RIPK3-Mediated Necroptosis and Neutrophil Infiltration Are Associated with Poor Prognosis in Patients with Alcoholic Cirrhosis by Zhenzhen Zhang, Guomin Xie, Li Liang, Hui Liu, Jing Pan, Hao Cheng, Hua Wang, Aijuan Qu, Yan Wang

“…Recent data suggests that receptor-interacting protein kinase-3- (RIPK3-) mediated necroptosis plays an important role in alcoholic cirrhosis. Additionally, neutrophil infiltration is the most characteristic pathologic hallmark of alcoholic hepatitis. …”
Get full text

miR-504 Promoted Gastric Cancer Cell Proliferation and Inhibited Cell Apoptosis by Targeting RBM4 by Yi Zhang, Hongmei Yong, Jing Fu, Guangyi Gao, Huichang Shi, Xueyi Zhou, Mingsheng Fu

“…The relative expression of miR-504 was significantly upregulated in the gastric cancer group (n=25) than in the paired normal group (n=25), but the relative RBM4 expression was remarkably downregulated in the gastric tumor group, compared with the normal group. Additionally, miR-504 overexpression increased the viability of gastric cancer cells. …”
Get full text

Ion Channel Expression and Characterization in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes by Zhihan Zhao, Huan Lan, Ibrahim El-Battrawy, Xin Li, Fanis Buljubasic, Katherine Sattler, Gökhan Yücel, Siegfried Lang, Malte Tiburcy, Wolfram-Hubertus Zimmermann, Lukas Cyganek, Jochen Utikal, Thomas Wieland, Martin Borggrefe, Xiao-Bo Zhou, Ibrahim Akin

“…Cardiomyocytes were derived from hiPS cells that were generated from two healthy donors. qPCR and patch clamp techniques were used for the study. Results. In addition to the reported ion channels, INa, ICa-L, ICa-T, If, INCX, IK1, Ito, IKr, IKs IKATP, IK-pH, ISK1–3, and ISK4, we detected both the expression and currents of ACh-activated (KACh) and Na+-activated (KNa) K+, volume-regulated and calcium-activated (Cl-Ca) Cl−, and TRPV channels. …”
Get full text

A kurtosis-ESPRIT algorithm for RealTime stability assessment in droop controlled microgrids by Adham Osama, Abdallah F. El-Hamalawy, Mohammed E. Ammar, Amr M. AbdelAty, Hatem H. Zeineldin, Tarek H. M. EL-Fouly, Ehab F. El-Saadany

“…In the proposed approach, a short-duration small disturbance is applied to the selected DG’s active power droop gain, and then, the system’s dominant modes are estimated from its local measurements. Additionally, a kurtosis measure is proposed as a quick measure to assess the estimation signal’s characteristics and evaluate the presence and prominence of significant modes within the signal. …”
Get full text

Seasonal Changes in Sleep Duration in African American and African College Students Living In Washington, D.C. by Janna Volkov, Kelly J. Rohan, Samina M. Yousufi, Minh-Chau Nguyen, Michael A. Jackson, Courtney M. Thrower, John W. Stiller, Teodor T. Postolache

“…In this study of African and African American college students, we hypothesized that students who met criteria for winter SAD or subsyndromal SAD (S-SAD) would report sleeping longer in winter than in summer. In addition, based on our previous observation that Africans report more “problems” with change in seasons than African Americans, we expected that the seasonal changes in sleep duration would be greater in African students than in African American students. …”
Get full text

Evaluation of Stability of Surface-Treated Mini-Implants in Diabetic Rabbits by Nam-Hee Oh, Eun-Young Kim, Janghyun Paek, Yoon-Ah Kook, Do-Min Jeong, Il-Sik Cho, Gerald Nelson

“…Type 1 diabetes mellitus and surface treatment method of mini-implant affected primary stability of mini-implants. In addition, the use of orthodontic mini-implants in a diabetic patient is likely to show results similar to the healthy patient.…”
Get full text