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57981
Small Interfering RNA Targeted to ASPP2 Promotes Progression of Experimental Proliferative Vitreoretinopathy
Published 2016-01-01“…EMT markers and related inflammatory and fibrosis cytokines were measured by western blot or flow cytometry. Additionally, PVR rat models were induced by intravitreal injection of ARPE-19 cells transfected with ASPP2-siRNA and evaluated accordingly. …”
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57982
Synoptic and Mesoscale Atmospheric Patterns That Triggered the Natural Disasters in the Metropolitan Region of Belo Horizonte, Brazil, in January 2020
Published 2025-01-01“…These findings highlight the importance of monitoring atmospheric conditions in conjunction with soil moisture over an extended period to provide additional information for mitigating the impacts of natural disasters.…”
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57983
A novel virtual inductor optimization methodology of virtual synchronous generators for enhanced power decoupling
Published 2025-04-01“…Finally, a series of comparative experiments is conducted to demonstrate its superior dynamic, static performance and enhanced power decoupling characteristics. In addition, a 15 kW inverter laboratory prototype controlled by StarSim rapid control prototyping (RCP) is used to test the proposed methodology. …”
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57984
Molecular structure influence of porous intrinsic polyimide nanofiber for high temperature flue gas filtration: Bisphenol AF, sulfone, ether bonds and hydroxyl groups
Published 2025-03-01“…After ODPA copolymerized modification, HFBAPP-6FDA-ODPA nanofiber membranes can reach a maximum of 95.42 %. In addition, the Tg and Td5 of all NFs reached 250 °C and 455 °C, indicating good thermal performance. …”
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57985
The Effects of Vitamin D on Gentamicin-Induced Acute Kidney Injury in Experimental Rat Model
Published 2013-01-01“…Thirty nonuremic Wistar albino rats were divided into 3 groups: Control group, 1 mL saline intramuscular (im) daily; Genta group, gentamicin 100 mg/kg/day (im); Genta + vitamin D, gentamicin 100 mg/kg/day (im) in addition to 1α, 25 (OH)2D3 0.4 mcg/kg/day subcutaneously for 8 days. …”
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57986
Well-Production Forecasting Using Machine Learning with Feature Selection and Automatic Hyperparameter Optimization
Published 2024-12-01“…By calculating the gray correlation degrees, maximum mutual information, feature importance, and Shapley additive explanation (SHAP) values, an in-depth analysis of various dominant factors was conducted. …”
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57987
Nuclear Factor-Kappa B Activity Regulates Brain Expression of P-Glycoprotein in the Kainic Acid-Induced Seizure Rats
Published 2011-01-01“…Furthermore, PDTC pre-treatment significantly decreased P-gp expression along with NF-κB activation in the hippocampus CA3 area and amygdala complex of rats compared with the EP group, implying that NF-κB activation involved in the seizure susceptibility and seizure induced brain P-gp over-expression. Additionally, DEX pre-treatment only decreased P-gp expression level without inhibition of NF-κB activation, suggesting NF-κB independent pathway may also participate in regulating seizure induced P-gp over-expression.…”
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57988
Direct-supply chilled-water radiant-floor cooling system coupled with an earth‒air heat exchanger system: A case study in a building
Published 2025-01-01“…The changes in the indoor air temperature and humidity and in the soil temperature when the two systems were operated independently were quantitatively analyzed. Additionally, the effects of the coupled DS-RFC/EAHE system on the indoor environment were evaluated for three air-supply inlet locations. …”
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57989
G Protein-Coupled Estrogen Receptor-Selective Ligands Modulate Endometrial Tumor Growth
Published 2013-01-01“…GPER/GPR30 is a 7-transmembrane spanning G protein-coupled receptor that has been identified as the third estrogen receptor, in addition to ERα and ERβ. High GPER expression is predictive of poor survival in endometrial and ovarian cancer, but despite this, the estrogen-mediated signaling pathways and specific estrogen receptors involved in endometrial cancer remain unclear. …”
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57990
Evaluation of Telenomus remus (Hymenoptera: Platygastridae) as a biocontrol agent of Spodoptera litura (Lepidoptera: Noctuidae) based on two-sex life table and functional response...
Published 2023-11-01“…Results T. remus can lay 186.90 eggs/female in the lifetime, adult preoviposition period was 0 days, total preoviposition period was 10.03 days, and the ratio of female and male offspring was 0.495 and 0.421, respectively. In addition, most females emerged from 24 h-old eggs, whereas most males emerged from 48 h-old eggs. …”
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57991
SURVEILLANCE OF PARASITIC DISEASES IN BULGARIA
Published 2025-01-01“… The incidence and number of cases of several parasitic diseases subject to mandatory reporting and registration under the Ministry of Health (MoH) 2005 Regulation 21 increased after the end of the global pandemic of COVID-19 in 2023. In addition, parasitic infections imported from endemic tropical regions are recorded annually in the country. …”
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57992
Conserved Nuclear Localization Signal in NS2 Protein of Bombyx Mori Bidensovirus: A Potential Invertebrate ssDNA Virus Trait
Published 2025-01-01“…To investigate its structure and function, we employed phylogenetic analysis, subcellular localization, mutational analysis, and a dual-luciferase reporter system to characterize the nuclear localization signal (NLS) within NS2 and its effect on viral promoter activity. Additionally, co-immunoprecipitation and mass spectrometry were utilized to identify host proteins interacting with NS2. …”
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57993
Assessing and predicting Bojiang lake area and LULC changes from 2000 to 2045
Published 2025-04-01“…Projections for 2024–2045 suggest further hydrological changes, with the lake area expected to increase by 42.67 %, reaching 12.17 km2 by 2045. Additionally, vegetation cover is expected to rise by 1.97 %, while barren land will decrease by 3.10 %. …”
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57994
Induced hepatocyte-like cells derived from adipose-derived stem cells alleviates liver injury in mice infected with Echinococcus Multilocularis
Published 2024-11-01“…Following transplantation, iHEPs were observed surrounding the metacestode lesions in the liver parenchyma of E. multilocularis-infected mice. iHEPs transplantation effectively restored liver function and improved liver injury in the infected mice. Additionally, we observed significant activation of the Wnt/β-catenin signaling pathway in the livers of infected mice transplanted with iHEPs. …”
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57995
A Comprehensive Analysis of Moist Versus Non‐Moist Dressings for Split‐Thickness Skin Graft Donor Sites: A Systematic Review and Meta‐Analysis
Published 2025-01-01“…Hydrocolloid dressings were particularly effective in accelerating wound healing. Additionally, moist dressings were associated with lower pain levels during dressing removal and had comparable rates of adverse events. …”
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57996
Improved differential protection for two-terminal weak feed AC system considering negative sequence control coordination strategy
Published 2025-03-01“…Simulation results show that the proposed protection scheme can resist higher fault impedance(300 Ω) and noise interference(25 dB). In addition, the proposed differential protection scheme is suitable for the protection requirements of the two terminal weak feed AC systems in different scenarios and has higher sensitivity.…”
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57997
Heme Oxygenase Induction Suppresses Hepatic Hepcidin and Rescues Ferroportin and Ferritin Expression in Obese Mice
Published 2017-01-01“…However, this effect is accompanied by a significant decline in ferritin expression. Additionally, there are reduced insulin receptor phosphorylation and attenuation of metabolic regulators pAMPK, pAKT, and pLKB1. …”
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57998
New digital drilling process monitoring: Instrumentation, validation and calibration
Published 2025-01-01“…Most importantly, this new instrument is proven to be successful in improving the detection of structural discontinuities with thicknesses >1 mm. In addition, by measuring the electric current of the driving motor, the torque applied to the bit is conveniently and accurately converted. …”
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57999
Targeted gut microbiome therapy: Applications and prospects of probiotics, fecal microbiota transplantation and natural products in the management of type 2 diabetes
Published 2025-03-01“…This review systematically summarizes the relationship between gut microbiota and T2DM, and explores the mechanisms through which gut microorganisms may alleviate T2DM. Additionally, it evaluates the potential of probiotics, fecal microbiota transplantation (FMT)/virome transplantation (FVT), and natural products in modulating gut microbiota to treat T2DM. …”
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58000
The Long-Term Outcome Comparison of Different Time-Delayed Kallikrein Treatments in a Mouse Cerebral Ischemic Model
Published 2018-01-01“…Three therapeutic regimens all protected against neurological dysfunction, but kallikrein treatment starting at 8 h after MCAO had the best efficacy. Additionally, kallikrein treatment at 8 h after MCAO significantly enhanced cell proliferation including neural stem cell and induced differentiation of neural stem cell into mature neuron. …”
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