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57921
Levels of Inflammatory Cytokines in Type 2 Diabetes Patients with Different Urinary Albumin Excretion Rates and Their Correlation with Clinical Variables
Published 2013-01-01“…Further studies are needed to fully establish the potential of these cytokines as additional biomarkers for the development of DN.…”
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57922
Fimasartan Ameliorates Nonalcoholic Fatty Liver Disease through PPARδ Regulation in Hyperlipidemic and Hypertensive Conditions
Published 2017-01-01“…Fimasartan decreased lipid contents in HepG2 and differentiated 3T3-L1 cells and liver tissues. In addition, fimasartan increased the adiponectin level in visceral fat tissues. …”
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57923
Pulsed Electromagnetic Field-Assisting Reduced Graphene Oxide-Incorporated Nanofibers for Osteogenic Differentiation of Human Dental Pulp Stem Cells
Published 2024-01-01“…However, current scaffold designs face limitations in combining structural guidance with effective electromagnetic stimulation. Additionally, delivering localized stimulation within scaffolds remains a challenge in maximizing the potential of these materials for bone regeneration. …”
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57924
Exploring grid sensitivity in an ice sheet model: A case study of the Amery Ice Shelf
Published 2024-12-01“…We observed that for the AmIS, grid resolutions coarser than 10 km in our model introduce considerable noise and reduce the ability to capture realistic dynamic processes. Additionally, we found that the inversion parameters were transferable between grid systems of different resolutions, and the AmIS exhibited a consistent response to idealized collapse scenarios across these grid systems, particularly for grids with a resolution of 10 km or finer. …”
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57925
Multilayer all-polymer metasurface stacked on optical fiber via sequential micro-punching process
Published 2023-02-01“…A 1550 nm laser beam passing through three metalens layers stacked on the fiber is focused at a distance of 135 μm with 83% efficiency. In addition, the 1550 nm beam passing through three OAM metasurfaces on the fiber is converted into a perfect vortex beam with a topological charge of 3. …”
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57926
Effects of <i>Lactiplantibacillus plantarum</i> on Metabolites and Flavors in Synthetic Microbiota During Baijiu Fermentation
Published 2024-12-01“…Our results demonstrated that the concentrations of ethyl lactate and other volatile aromatic compounds increased in all fermentation protocols where <i>L. plantarum</i> was added. The addition of <i>L. plantarum</i> also significantly increased the concentration of total organic acids, particularly lactic acid, which rose by 17 to 123 times. …”
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57927
Noncoding RNA profiling in omentum adipose tissue from obese patients and the identification of novel metabolic biomarkers
Published 2025-02-01“…The aim of this study was to identify additional ncRNA candidates that are implicated in obesity, elucidating their potential as key regulators of the pathogenesis of obesity.MethodsWe identified distinct ncRNA expression profiles in omental adipose tissue in obese and healthy subjects through comprehensive whole-transcriptome sequencing. …”
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57928
Cecropin AD ameliorates pneumonia and intestinal injury in mice with mycoplasma pneumoniae by mediating gut microbiota
Published 2025-01-01“…The findings showed that mice receiving twice injections of 2.08 × 108 copies of Mccp suffered significant pathological damage to their lungs and colons. Additionally, there was a notable upsurge in inflammatory factors within the affected tissues. 16 S rDNA sequencing revealed alterations in the colonic microbiota, including a decrease in the abundance of beneficial bacteria such as Corynebacterium_glutamicum and Candidatus_Saccharimonas, and an increase in the abundance of potential pathogens like Lachnospiraceae_NK4A136_group and Escherichia-Shigella. …”
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57929
Dose-dependent enhancement of in vitro osteogenic activity on strontium-decorated polyetheretherketone
Published 2025-01-01“…The boosted osteogenic activity of strontium-modified PEEK samples has been demonstrated by the better performed of ALP activity, extracellular matrix mineralization, collagen secretion, and the remarkable up-regulation of ALP, OCN, OPN, Runx2, Col-I, BSP, and OSX of the MC3T3-E1 pre-osteoblasts. Additionally, the strontium-modified PEEK samples exhibit a dose-dependent enhancement of osteoblasts compatibility and osteogenic activity, and the PEEK-Sr10 group shows the best. …”
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57930
Beamline and Flight Comparisons of the ARMAS Flight Module With the Tissue Equivalent Proportional Counter for Improving Atmospheric Radiation Monitoring Accuracy
Published 2020-12-01“…Both detectors were flown onboard commercial and research aircraft. In addition, both detectors were exposed neutrons at the Los Alamos Neutron Science Center, protons at Loma Linda University Medical Center, 56Fe particles at the NASA Space Radiation Laboratory, and also a gamma radiation source at Lawrence Livermore National Laboratory. …”
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57931
Consensus on rapid screening for prodromal Alzheimer’s disease in China
Published 2024-02-01“…Recommended screening methods are presented in this publication, including neuropsychological assessment, peripheral biomarkers and brain imaging. In addition, a general workflow for screening pAD in China is established, which will help clinicians identify individuals at high risk and determine therapeutic targets.…”
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57932
Time series forecasting techniques applied to hydroelectric generation systems
Published 2025-03-01“…Most of the reviews found in the literature are broader and include optimization and control approaches in hydroelectric systems. In addition, the literature lacks research works revising and analyzing the application of time series forecasting techniques –from statistics, machine and deep learning, and soft computing– to hydropower production –in contrast to the other topics that have been more thoroughly studied, such as energy demand in buildings. …”
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57933
The Formation of a Multifilament System Driven by Photospheric Converging Motions in a Bipolar Sunspot
Published 2025-01-01“…These two filament segments further reconnected, forming a long coherent filament and resulting in a double-decker configuration. In addition, continuous converging motion and magnetic flux cancellation were found in the photosphere during the evolution. …”
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57934
Electrochemical CO2 Reduction: Commercial Innovations and Prospects
Published 2025-01-01“…Specifically, three eCO2RR products – CO, HCOOH, and C2H4 – as promising candidates for implementation are elaborated based on techno‐economic considerations. Additionally, the review discusses the industrial blueprint for these products, aiming to streamline their path toward commercialization. …”
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57935
Development of a new yarn supply for weft knitting machines to produce innovative knitwear
Published 2023-02-01“…Furthermore, a fourth yarn can be implemented to insert a weft yarn. Additionally, the two single-faced fabrics can be produced simultaneously in the same carriage stroke in the front and rear needle beds. …”
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57936
Factors associated with maternal mortality in Ica, Peru: A matched case-control study
Published 2024-12-01“…To reduce preventable maternal mortality, it is essential to collaborate between the Ministry of Health of Peru and regional governments, aiming to expand coverage and improve the quality of prenatal care. Additionally, awareness should be increased and transportation availability ensured 24 hours a day for women experiencing obstetric complications. …”
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57937
Design of an equilibrative nucleoside transporter subtype 1 inhibitor for pain relief
Published 2024-12-01“…Notably, our ENT1 inhibitor surpasses gabapentin in analgesic efficacy in a neuropathic pain model. Additionally, our inhibitor exhibits less cardiac side effect than dilazep via systemic administration and shows no side effects via local/intrathecal administration. …”
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57938
IL-17 Affects the Progression, Metastasis, and Recurrence of Laryngeal Cancer via the Inhibition of Apoptosis through Activation of the PI3K/AKT/FAS/FASL Pathways
Published 2020-01-01“…Moreover, high IL-17 expression was significantly associated with the advanced T category, the late clinical stage, differentiation, lymph node metastasis, and recurrence. In addition, the time course expression of FAS and FASL was observed after stimulation and treatment with the IL-17 stimulator. …”
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57939
Agroforestry systems favor bat conservation but only when old and grazed
Published 2025-01-01“…Bat activity in silvopastoral systems was two times higher than in pastures and orchards and four times higher than in cropland. In addition, social calls and foraging rates of bats were highest in silvopastoral systems. …”
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57940
Portable wide-field digital imaging for screening of neonatal visual impairment causes in Rio de Janeiro, Brazil: a budget impact analysis
Published 2022-06-01“…The secondary outcome was the budget impact of implementing portable wide-field digital image screening in Rio de Janeiro, Brazil.Results Considering 100% coverage of maternity wards, the total budget impact between 2020 and 2024 would be US$3 820 706.04, ranging from US$3 139 844.34 to US$6 099 510.35. The additional cost would be US$3 124 457.28, ranging from US$2 714 492.26 to US$4 880 608.63.Conclusion The cost of universal digital imaging screening corresponds to less than 1% of the government health budget of the city of Rio de Janeiro. …”
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