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57301
Spectroscopic and Theoretical Studies of Hg(II) Complexation with Some Dicysteinyl Tetrapeptides
Published 2021-01-01“…These structural insights on peripheral mercury-peptide interactions provide additional understanding of the chemistry of mercury(II) with side-chain donor groups in peptides.…”
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57302
Astrocytic HIV-1 Nef Expression Decreases Glutamate Transporter Expression in the Nucleus Accumbens and Increases Cocaine-Seeking Behavior in Rats
Published 2025-01-01“…Results: The findings indicate that both cocaine and Nef independently decrease the expression of the glutamate transporter GLT-1 in the NAc. Additionally, rats with astrocytic Nef expression exhibited increased cocaine-seeking behavior but demonstrated sex-dependent molecular differences after the behavioral paradigm. …”
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57303
Exercise-Induced Adaptations to the Mouse Striatal Adenosine System
Published 2020-01-01“…This study investigated the effects of long-term voluntary wheel running on adenosine 1 (A1R), adenosine 2A (A2AR), dopamine 1 (D1R), and dopamine 2 (D2R) receptor protein expression in adult mouse dorsal and ventral striatum structures using immunohistochemistry. In addition, equilibrative nucleoside transporter 1 (ENT1) protein expression was examined after wheel running, as ENT1 regulates the bidirectional flux of adenosine between intra- and extracellular space. …”
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57304
Neutralization by Insulin of the Hypertensive Effect of Dermcidin Isoform 2: An Environmentally Induced Diabetogenic and Hypertensive Protein
Published 2014-01-01“…Ingestion of acetyl salicylic acid (aspirin) (150 mg/70 kg body weight) decreased the systolic and diastolic pressures to 125 mm and 80 mm of Hg, respectively, with decrease of dermcidin level to 15 nM. …”
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57305
Exploring the Effects of Sub-Dissociative Doses of Ketamine on Sedation Quality in Bronchoscopy: A Double-Blind Clinical Study
Published 2024-10-01“…Furthermore, the satisfaction levels reported by the bronchoscopist (P=0.78) and the participants (P=0.019) were notably greater in the SDK3 cohort than in the other groups. Additionally, the amount of propofol administered to the SDK3 cohort was less than that given to the SDK2, and both cohort received lower doses than the SDK1 cohort (P>0.001). …”
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57306
Nonclinical Similarity of the Biosimilar Candidate ABP 938 with Aflibercept Reference Product
Published 2024-11-01“…Results from the nonterminal ocular distribution study in rabbits indicated that there were no meaningful differences in the distribution kinetics between intravitreally injected ABP 938 and aflibercept RP. Additionally, there was no evidence of ocular or systemic toxicity associated with IVT administration of ABP 938 in a repeat-dose, 1-month toxicology study in cynomolgus monkeys; toxicokinetic and toxicology profiles were similar to aflibercept RP. …”
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57307
Ecological Upgrade of Normal-Strength Mortars by Using High Volume of GGBS
Published 2020-01-01“…For instance, raising the curing temperature to 40°C can help achieve higher early-age compressive strength than that of the control group. In addition, the pore sizes within ZII (<100 nm) of GGBS-incorporated NSM were refined by over 20 nm.…”
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57308
Quid du port romain estuarien de Barzan (Charente-Maritime) ?
Published 2020-12-01“…The results obtained from the geophysical survey reveal imposing remains, of various natures, which could correspond to one of the major harbour systems of the civitas Santonum. In addition, this sector is likely to provide palaeo-environmental information whose importance goes beyond the Barzan site.…”
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57309
NGS sequencing in barley breeding and genetic studies
Published 2020-07-01“…SNP identification associated with economically important traits and their transformation into CAPS or KASP markers convenient for screening selection material significantly expands the possibilities of marker-assisted selection of barley. In addition, the currently available information on potential target genes and the quality of the whole barley genome sequence provides a good base for applying genome editing technologies to create material for the creation of varieties with desired properties.…”
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57310
Economic Evaluation of Boceprevir for the Treatment of Patients with Genotype 1 Chronic Hepatitis C Virus Infection in Hungary
Published 2013-06-01“…**Conclusion:** The addition of boceprevir to standard therapy for the treatment of patients with genotype 1 chronic HCV infection in Hungary is projected to be cost-effective using a commonly used willingness to pay threshold of HUF 8.46 million (3 times gross domestic product per capita).…”
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57311
Analyzing the Origin of Low Resistivity in Gas-Bearing Tight Sandstone Reservoir
Published 2021-01-01“…The results indicated that when there is no or a low degree of mud invasion, the fine lithology, complex pore structure, additional clay mineral conductivity, and high content of pyrite are the main internal factors driving the conditions present in the studied gas reservoir. …”
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57312
Anti-Inflammatory Effects of Aster incisus through the Inhibition of NF-κB, MAPK, and Akt Pathways in LPS-Stimulated RAW 264.7 Macrophages
Published 2018-01-01“…Our WST-1 assay results revealed that Aster incisus did not affect the viability of all tested cell lines up to a concentration of 200 μg/ml; therefore, lower concentrations (50 μg/ml and 150 μg/ml) were used for further assays. …”
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57313
The New York Times on The NATO bombing of FR Yugoslavia in 1999
Published 2025-01-01“…The most extreme example of mitigated vocabulary is the depiction of bombings as fireworks, which not only attempts to cover up the violence and suffering of innocent people but also turns it into a celebration. Additionally, beyond the stereotypical depiction of the military attacks themselves, the relationship between the two opposing sides is portrayed in a clichéd and simplified manner. …”
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57314
Ultra-Low Static Power Circuits Addressing the Fan-Out Problem of Analog Neuron Circuits in Spiking Neural Networks
Published 2025-01-01“…When simulated with a <inline-formula> <tex-math notation="LaTeX">$512\times 512$ </tex-math></inline-formula> scale post-synaptic resistive random-access memory array, the neuron circuit with proposed fan-out circuits demonstrated an energy consumption of 447 pJ/spike, including the power to drive the synaptic arrays. In addition, the proposed fan-out circuit enables low-power operation, even at low firing rates, owing to its ultra-low static power consumption. …”
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57315
Systematic review of depressive, anxiety and post-traumatic stress symptoms among Asian American breast cancer survivors
Published 2020-09-01“…Intervention studies were limited, but the use of community-based participatory research approaches and cultural adaptations were noted strengths of the studies.Discussion In addition to discussing clinical implications, we highlight limitations of the literature, including a lack of longitudinal studies and the limited use of standardised diagnostic instruments for assessing psychopathology symptoms among this population. …”
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57316
In vitro sperm generation from immature mouse testicular tissue using plasma rich in growth factors
Published 2025-01-01“…However, after 42 days, the integrity scoring revealed significantly a higher percentage of well-preserved tubules in 5% PRGF compared to 10% KSR. Additionally, only PRGF supported spermatogenesis to the production of flagellated sperm. …”
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57317
METHOD FOR EFFECTIVE SEPARATION OF MICROPLASTIC PARTICLES FROM BOTTOM SEDIMENTS
Published 2024-09-01“…The size of the grinding platform and the availability of additional elements guarantee the ability to work with containers of various volumes, shapes, and sizes. …”
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57318
Assessing Redox Properties of Natural Organic Matters with regard to Electron Exchange Capacity and Redox-Active Functional Groups
Published 2020-01-01“…An increasing in EEC (EAC + EDC, where EAC is the electron accepting capacity and EDC is the electron donating capacity) of LMWF PPNOM and LNOM with Eh reduced from −0.49 V to −0.69 V. Additionally, an obvious increase in fluorescent intensities of quinone-like fluorophores before and after being reduced LMWF LNOM is responsible for high EAC of LMWF LNOM. …”
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57319
Effectiveness of Tailored Multisensory Stimulation Intervention in People with Major Neurocognitive Disorder: A Quasiexperimental Pilot Study
Published 2024-01-01“…They were happier, more attentive to their environment, active/alert, and relaxed/content after sessions. In addition, immediately after their sessions, they were less tearful/sad, fearful/anxious, confused, and wandering/aggressive, as well as less bored/inactive. …”
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57320
Orphan nuclear receptor NR2E3 is a new molecular vulnerability in solid tumors by activating p53
Published 2025-01-01“…Moreover, we show that the small-molecule agonist of NR2E3, 11a, penetrates tumor mass of uterine cancer patients and increases p53 activation. Additionally, both NR2E3 and 11a exhibit similar multifaceted anti-cancer properties, underscoring NR2E3 as a novel molecular vulnerability in cancer cells. …”
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