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57021
Elucidating stearoyl metabolism and NCOA4-mediated ferroptosis in gastric cancer liver metastasis through multi-omics single-cell integrative mendelian analysis: advancing personal...
Published 2025-01-01“…Conclusion This study enhances the understanding of the relationship between stearoyl metabolism and ferroptosis in promoting liver metastasis of gastric cancer and its role in the regulation of tumor heterogeneity. In addition, this study contributes to a deeper understanding of the dynamics of gastric cancer tumor microenvironment (TME) and provides a basis for the development of better interventions to combat cancer metastasis.…”
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57022
A Lightweight YOLO Model for Rice Panicle Detection in Fields Based on UAV Aerial Images
Published 2024-12-01“…However, intensive planting, complex growth environments, and the overlapping of rice panicles and leaves in paddy fields pose significant challenges for precise panicle detection. …”
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57023
Control of two-spotted spider mite, Tetranychus urticae, on strawberry by integrating with cyetpyrafen and Phytoseiulus persimilis
Published 2023-11-01“…The results suggested that cyetpyrafen revealed no substantial differences in prey consumption or longevity when compared to the control, though minor effects on the development durations of protonymphs and deutonymphs were noted in the subsequent generation. Additionally, cyetpyrafen's toxicity on key pollinators, such as Apis mellifera and Bombus terrestris, was found to be low. …”
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57024
Comparative Efficacy and Safety of Targeted Therapies for Chronic Thromboembolic Pulmonary Hypertension: A Systematic Review and Network Meta-Analysis
Published 2021-01-01“…We searched PubMed, EMBASE, Web of Science, the Cochrane Central Register, https://clinicaltrials.gov, and who.int/trialsearch/, for relevant RCTs published up to January 2020. In addition to traditional meta-analysis, we also performed NMA in our systematic review, as deployed in a previous protocol (PROSPERO: CRD42020173765). …”
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57025
Machine Learning Model Reveals Land Use and Climate’s Role in Caatinga Wildfires: Present and Future Scenarios
Published 2024-12-01“…Future research should incorporate additional variables, such as vegetation recovery and socio-economic factors, to refine predictions. …”
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57026
Lung adenocarcinoma metastasis within a pituitary neuroendocrine tumor: a case report with review of literature
Published 2024-03-01“…Genetic testing revealed the presence of an EGFR (Ex-19del) mutation, after which chemotherapy was initiated. Additional stereotactic radiotherapy was performed for the residual tumor in the sella turcica. …”
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57027
A comprehensive review on eutectic phase change materials: Development, thermophysical properties, thermal stability, reliability, and applications
Published 2025-01-01“…The low thermal conductivity of organic eutectics can be eliminated with suitable nanoparticle additives. The leakage issue can be eliminated by providing shape stabilization to the PCMs. …”
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57028
Significance of Linked Color Imaging for Predicting the Risk of Clinical Relapse in Ulcerative Colitis
Published 2020-01-01“…We assessed the correlation between orange-like color lesion (defined as LCI-scarlet color lesions) and clinical relapse rate (requiring additional treatment for UC) during the 1-year follow-up period. …”
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57029
Dual-frequency ultrasonic-assisted enzymolysis for synthesis of microstructure regulated biomass-derived porous carbon for high-performance supercapacitors
Published 2025-01-01“…As anticipated, DUGPC demonstrates excellent specific capacitance (408.77 F/g at 1 A/g) and rate performance (retention is 81.8 % at 50 A/g) surpassing most recently reported biomass-based PCs. In addition, the assembled aqueous symmetric supercapacitor achieves an excellent energy density of 15.78 Wh kg−1 at a power density of 50.04 W kg−1 with a remarkable cycle stability of 95.5 % after 10,000 cycles at 5 A/g, and the assembled 2.8 V high-voltage organic supercapacitor even exhibits an ultra-high energy density of 58.96 Wh kg−1 at a power density of 139.86 W kg−1. …”
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57030
Tiny clue reveals the general trend: a bibliometric and visualized analysis of renal microcirculation
Published 2024-12-01“…The co-occurrence of keywords and co-cited references were analyzed using CiteSpace6.1.R6 software to generate visualization maps. Additionally, burst detection was applied to keywords and cited references to forecast research hotspots and future trends.Results Our search yielded 7462 publications, with the American Journal of Physiology-Renal Physiology contributing the most articles. …”
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57031
Single-cell analyses of intestinal epithelium reveal the dysregulation of gut immune microenvironment in systemic lupus erythematosus
Published 2025-01-01“…Results We observed a significant reduction in CD8αα + IELs, accompanied by a marked increase in CD8αβ + IELs in Lpr mice. Additionally, subsets of CD8 + IELs exhibiting significantly enhanced effector functions were found to be markedly enriched in Lpr mice. …”
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57032
Effect of custom-designed transfection buffer on delivery of genome modification components into primary cells of buffalo, cattle, goats, and sheep
Published 2023-11-01“…We also noticed that cell viability and proliferation rates were better in the case of goats, sheep, and cattle cells; also, these cells have less vacuolation than buffalo cells. In addition, we also generated MSTN (myostatin) KO (Knockout) cell clones from these cell populations, in which the efficiency of single-cell clone generation was high for goats and sheep cells. …”
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57033
Animal and bird-related ocular trauma: a decade of experience from a tertiary referral eye hospital of Iran
Published 2025-01-01“…Rural patients had a significantly longer time interval from trauma occurrence to hospital admission (83.58 ± 31.46 h in the rural group vs. 29.85 ± 6.48 h in the urban group, P-value = 0.012) and from hospital admission to the first surgical intervention (8.8 ± 1.14 h in the rural group vs. 6.83 ± 6.13 h in the urban group, P-value = 0.020). Additionally, final visual acuity was significantly better in urban patients than in rural patients. …”
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57034
Enhanced automated text categorization via Aquila optimizer with deep learning for Arabic news articles
Published 2025-01-01“…The TCAODL-ANA technique follows pre-processing and the FastText word embedding process to accomplish this. In addition, the TCAODL-ANA technique utilizes an effective attention-based bidirectional gated recurrent unit (ABiGRU) method to identify various news articles. …”
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57035
Occupational exposure to flame retardants following production replacement and their effect on thyroid function indicators
Published 2025-06-01“…The results showed that the detection frequencies of only triphenyl phosphate (TPHP), BDE-138 and BDE-197 (82.4 %, 61.2 % and 60.6 %, respectively) exceeded 60 % among the 34 compounds of interest, while the median concentrations of BDE-138 and BDE-197 were much higher than TPHP (medians of 103.6, 60.6 and 20.5 ng/g lw, respectively). In addition, the concentrations of these compounds in exposed group are higher than those in the control group (P < 0.05). …”
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57036
Effective gene therapy for metachromatic leukodystrophy achieved with minimal lentiviral genomic integrations
Published 2025-03-01“…To address this need, we increased the expression of ARSA cDNA at single integration by generating novel LVs, optimizing ARSA expression and enhancing safety. In addition, our vectors achieved optimal transduction in mouse and human hematopoietic stem cells (HSCs) with minimal multiplicity of infection (MOI). …”
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57037
Association of multiple environmental exposures with rhinitis and asthma symptoms in preschool children: Identifying critical risk factor
Published 2025-01-01“…Random forest ranking analysis further corroborated the most significant environmental exposure for rhinitis alone was PM1, and for wheezing symptoms (both wheezing & rhinitis and wheezing alone) was NO2. Significant additive and multiplicative interactions were examined between indoor dampness and PM1 exposure on rhinitis alone. …”
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57038
Cognitive control in individuals with heroin use disorder after prolonged methadone maintenance treatment
Published 2025-01-01“…Results HUD individuals exhibited worse saccade error rate and executive dysfunction but showed no significant impairment in prospective memory. Additionally, the relapsers performed worse in terms of antisaccade amplitude and velocity at higher difficulty gradients (11° or 16°). …”
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57039
Patients’ acceptability and implementation outcomes of a case management approach to encourage participation in colorectal cancer screening for people with schizophrenia: a qualita...
Published 2022-06-01“…Interviews were conducted with patients who received the intervention and staff from two psychiatric hospitals in Japan who delivered the intervention.Participants Of the 172 patients with schizophrenia who participated in the trial, 153 were included. In addition, three out of six providers were included.Data collection and analysis Using a structured interview, the case manager asked participants about patient acceptability and the helpful components of the intervention. …”
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57040
AaMYB61-like and AabHLH137 jointly regulate anthocyanin biosynthesis in Actinidia arguta
Published 2025-01-01“…Y1H and LUC assays revealed that AaMYB61-like activates the promoters of AaCHS, AaLDOX, and AaF3GT. In addition, AabHLH137 was found to be related to fruit color from the transcriptome data. …”
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