CRISPR/Cas9, a universal tool for genomic engineering by A. V. Smirnov, A. M. Yunusova, V. A. Lukyanchikova, N. R. Battulin

“…CRISPR/Cas9 proved to be especially useful in pronuclear microinjections of farm animals as well, having strong impact on biotechnology. In addition, we review Cas9-augmented genetic screens that allow an unbiased search for new genes and pathways involved in a plethora of biological aspects, owing to Cas9 efficiency and versatility. …”
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Healthcare consumers' perceptions of incentive-linked prescribing: A scoping review. by Muhammad Naveed Noor, Haider Safdar Abbasi, Nina van Der Mark, Zahida Azizullah, Janice Linton, Afifah Rahman-Shepherd, Amna Rehana Siddiqui, Mishal Sameer Khan, Rumina Hasan, Sadia Shakoor

“…HCCs perceived several hazards linked to ILP such as a lack of trust in physicians and the healthcare system, the prescribing of unnecessary medications, and the negative effect on physicians' reputations in society. In addition to strong regulatory controls, it is critical that physicians self-regulate their behaviour, and publicly disclose if they have any financial ties with pharmaceutical companies. …”
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Knowledge, attitudes and practices towards COVID-19 among multiethnic elderly Asian residents in Singapore: a mixed-methods study by Amudha Aravindhan, Alfred Tau Liang Gan, Ester Pei Xuan Lee, Preeti Gupta, Ryan Man, Kam Chun Ho, Sharon Cohan Sung, Ching-Yu Cheng, Moi Lin Ling, Hiang Khoon Tan, Tien Yin Wong, Eva Katie Fenwick, Ecosse Luc Lamoureux

“…Compared to Chinese, Indians had lower odds of practising three out of six recommendations. …”
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Deodorization of Egg White Powder by Ozone Treatment and Underlying Mechanism by XIN Xiaojuan, LIU Ying, MA Lulu, HUO Jiaying, GAO Ying, DONG Shijian, LIU Liya, WANG Fengzhong, LI Shugang

“…The sensory off-flavor score reached its lowest point (which decreased by 75% compared with the untreated group) after 20 min of ozone treatment, when egg white protein was slightly oxidized, leading to protein unfolding and structural disordering, increased carbonyl content and particle size, and decreased endogenous fluorescence intensity. In addition, fluorescence quenching and molecular docking showed that the major binding force between egg white protein and off-flavor substances was hydrophobic interaction, and their main binding sites were in a hydrophobic cavity composed of amino acids such as Leu66, Lys69, Glu87E, Ala87F, Cys87H, Glu129, Tyr130, Cys133, and Gly320. …”
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Symptoms and coronary risk factors predictive of adverse cardiac events in chest pain patients in an Asian emergency department: the need for a local prediction score by Ziwei Lin, Swee Han Lim, Qai Ven Yap, Cheryl Shumin Kow, Yiong Huak Chan, Siang Jin Terrance Chua, Anantharaman Venkataraman

“…Random glucose and direct low-density lipoprotein measurements were taken, in addition to serial troponin. We derived the age, coronary risk factors (CRF), sex and symptoms (ACSS) risk score based on multivariate analysis results, considering age, CRF, sex and symptoms and classifying patients into very low, low, moderate and high risk for MACE. …”
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Phillyrin ameliorates DSS-induced colitis in mice via modulating the gut microbiota and inhibiting the NF-κB/MLCK pathway by Tong Li, Guiqiu Hu, Shoupeng Fu, Di Qin, Zheyu Song

“…The outcomes of 16S rRNA sequencing suggest that PHY (50 mg/kg) augmented the relative abundance of certain probiotic strains, including Lactobacillaceae and Lachnospiraceae. Additionally, PHY supplementation elevated the short-chain fatty acid contents within the intestinal contents of mice with UC. …”
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Reduced Cardiovascular Capacity and Resting Metabolic Rate in Men with Prostate Cancer Undergoing Androgen Deprivation: A Comprehensive Cross-Sectional Investigation by Bradley A. Wall, Daniel A. Galvão, Naeem Fatehee, Dennis R. Taaffe, Nigel Spry, David Joseph, Robert U. Newton

“…To investigate if androgen deprivation therapy exposure is associated with additional risk factors for cardiovascular disease and metabolic treatment-related toxicities. …”
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Exploring intersectional determinants of, and interventions for, low uptake of human papillomavirus vaccine in sub-Saharan Africa: a scoping review protocol by Peter Ntoiti Kailemia, Victoria Mukami

“…This scoping review aims to integrate evidence from SSA on social determinants of HPV vaccine uptake with complementary evidence on interventions to promote its uptake.Methods and analysis The proposed review will be conducted following the guidelines of the Joanna Briggs Institute Scoping Review Methodology Group. Additionally, a sequential explanatory design will guide the integration of determinant evidence with intervention evidence. …”
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The role of teachers’ beliefs and professional development in students’ mathematics motivation in primary education by Laura H. L. Niemi, Marja Holm, Eeva Haataja, Pia Ilomanni, Anu Laine

“…Establishing a direct connection between teacher self-efficacy and student motivation is challenging because it affects motivation indirectly, for example, through teaching methods. Additionally, the role of the teacher in fostering motivation is relatively small and unstable in the early years. …”
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Association between exposure to urinary metal and all-cause and cardiovascular mortality in US adults. by Ting Cheng, Dongdong Yu, Geng Li, Xiankun Chen, Li Zhou, Zehuai Wen

“…We estimated the association between urine metal exposure and all-cause mortality using Cox regression, weighted quantile sum (WQS) regression, and Bayesian kernel machine regression (BKMR) models. Additionally, we used a competing risk model to estimate the relationship between metal exposure and cardiovascular mortality.…”
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Evaluation of Bioactive Compounds and Chemical Elements in Herbs: Effectiveness of Choline Chloride-Based Deep Eutectic Solvents in Ultrasound-Assisted Extraction by Aleksandra Szydłowska-Czerniak, Agnieszka Kowaluk, Michał Strzelec, Tomasz Sawicki, Małgorzata Tańska

“…Unexpectedly, the selected green solvents extracted significantly lower amounts of total antioxidants from the investigated herbs than 50% alcohols. Additionally, macroelements (K, Na, Ca, Mg), micronutrients (Mn, Zn, Fe, Cu), and a toxic element (Cd) in four herbs were analyzed using inductively coupled plasma–mass spectrometry (ICP–MS). …”
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GPR55 in the tumor microenvironment of pancreatic cancer controls tumorigenesis by Dušica Ristić, Thomas Bärnthaler, Eva Gruden, Melanie Kienzl, Laura Danner, Karolina Herceg, Arailym Sarsembayeva, Julia Kargl, Rudolf Schicho

Subjects: “…KPCY model…”
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Perceptions of care and family support from patients and family caregivers during the COVID-19 pandemic: a phenomenological study in Spain by Joana Maria Julià-Móra, Margarita Calafell-Vert, Francesca Rosa Rosal-Obrador, Ian Blanco-Mavillard, Margalida Miró-Bonet

“…Participants highlighted the critical role of family presence in improving emotional stability and physical recovery, hinting at the importance of fostering psychological resilience in healthcare settings. Additionally, the study revealed inconsistencies in the communication and dissemination of information, which aggravated stress and confusion among participants. …”
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Humoral and Cellular Immune Regulation in Albino Rat Exposed to Glyphosate and Aluminum Phosphide by Ujuamala Ezeani, Onyemaechi Afonne, Michael Ezeani

“…Subsequently, there was a significant increase in CD8+ values at the first, second and third months after exposure to GLP and ALP (p<0.001 for all). Additionally, there was a notable reduction in CD4+ levels at the second and third months post-exposure (p=0.001 and p<0.001, respectively).Conclusion: This study identified a deregulation of the immune system characterized by a progressive immunosuppression of CD4 T cell counts, indicating a down regulation of antibody-mediated (humoral) immune responses alongside an up regulation of cytotoxic T cells. …”
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The Optimal Timing of Strategic Action – A Real Options Approach by Gordon G. Sollars, Sorin Tuluca

“…The strategic management literature reflects ambiguity regarding the likelihood that a first mover can or will capture additional value. This paper uses a real options approach to address the optimal timing of strategic moves. …”
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Isokinetic Training Program to Improve the Physical Function and Muscular Performance of an Individual with Partial Injury of the Medial Meniscus: A Case Report by Karen Obara, Pedro Silva, Mariana Silva, Fagner Mendes, Gabriel Santiago, Ihan Oliveira, Jefferson Cardoso

“…He completed an isokinetic training program in addition to exercises that targeted proprioception (22 sessions, 11 weeks) to improve physical function and performance, which were assessed before and after treatment and at a six-month follow-up. …”
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Hemoglobin I from Lucina pectinata on Collagen Scaffold: A Prospective Hydrogen Sulfide Scavenger by Jennifer Vargas Santiago, Anibal Quintana Cheeseborough, Juan López-Garriga

“…Given the rapid diffusivity of the gas, it is a challenge to develop robust sensors and biomarkers to quantify free or bound H2S. In addition, there is the need to further develop a robust biosystem to efficiently trap or scavenge H2S from different producing environments. …”
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Evaluation of Dermatology Treatment Satisfaction towards Hospital Reputation among Chronic Skin Disease Patients at An Eastern Indonesian Referral Hospital by Shienty Gaspersz, Ferdi Antonio, Paulus Mario Christopher

“…This study aimed to evaluate the factor of treatment satisfaction moderated with recurrency towards hospital reputation among patients with chronic skin disorder utilizing the modified Dermasat questionnaire with six variables (treatment effectiveness, convenience of use, impact on daily living, medical care information, treatment side effect tolerable) and an additional variable (physician communication). Methods :Based on improved patient satisfaction moderated with recurrency towards hospital reputation, a questionnaire survey was conducted among 179 patients at a referral hospital in East Indonesia. …”
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The Effect of Common Knowledge Construction Model-Based Instruction on 5th Grade Students' Conceptual Understanding of Biodiversity by Veysel Haydari, Bayram Costu

“…Kruskal Wallis H-Test and Wilcoxon paired pairs test are employed to analyze the data. In addition, Tamhane’s T2 test is employed from post hoc tests to determine the direction of the difference of biodiversity post-test scores. …”
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Visible light photocatalytic efficiency and corrosion resistance of Zn, Ni, and Cu-doped TiO2 coatings by Mona Khalaghi, Masoud Atapour, Mohamad Mohsen Momeni, Mohammad Reza Karampoor

“…Morphology and wettability tests indicate that the addition of dopants into TiO2 thin films can develop compact structures with a lower crystallite size, improved surface area, and hydrophilic surfaces. …”
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