Nano-Zinc Oxide Can Enhance the Tolerance of Apple Rootstock M9-T337 Seedlings to Saline Alkali Stress by Initiating a Variety of Physiological and Biochemical Pathways by Jietao Zhai, Xulin Xian, Zhongxing Zhang, Yanxiu Wang

“…ZnO NPs can balance the osmotic adjustment system by increasing the contents of soluble protein (SP), soluble sugar (SS), proline (Pro) and starch, and can also enhance the activities of enzymatic (SOD, POD, and CAT) and non-enzymatic antioxidant enzymes (APX, AAO, GR, and MDHAR) to enhance the scavenging ability of reactive oxygen species (H₂O₂, O₂^•−), ultimately reducing oxidative damage; ZnO NPs promoted the growth of M9-T337 seedlings under saline alkali stress by synergistically responding to auxin (IAA), gibberellin (GA₃), zeatin (ZT) and abscisic acid (ABA). Additionally, the Na⁺/K⁺ ratio was reduced by upregulating the expression of Na⁺ transporter genes (<i>MdCAX5</i>, <i>MdCHX15</i>, <i>MdSOS1</i>, and <i>MdALT1</i>) and downregulating the expression of K⁺ transporter genes (<i>MdSKOR</i> and <i>MdNHX4</i>). …”
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Genomic characteristics of ST6115 carbapenem-resistant Klebsiella pneumoniae coharboring blaNDM-1 and blaIMP-4 by Xiaofang Xie, Xiaofang Xie, Yaxuan Zhai, Zhichen Zhu, Feinan Qian, Feinan Qian, Jie Zhu, Qizhao Gao, Hong Du, Hong Du

“…Finally, the conjugation transfer experiment was conducted to assess the transferability of the plasmid pHD8428-NDM-IMP.ResultsA comparable phylogenetic analysis revealed that ST6115 HD8428 and the majority of ST17 strains (9/12) were clustered on the same clade, which suggests a close relationship between two ST types. Additionally, HD8428 showed particularly close genetic similarity to HD11490, with a single-nucleotide polymorphism (SNP) difference of only 273. …”
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Randomized, observer-blind, controlled Phase 1 study of the safety and immunogenicity of the Na-GST-1/Alhydrogel hookworm vaccine with or without a CpG ODN adjuvant in hookworm-naï... by David J Diemert, Maria Zumer, Mark Bova, Christina Gibbs-Tewary, Elissa M Malkin, Doreen Campbell, Lara Hoeweler, Guangzhao Li, Maria Elena Bottazzi, Peter J Hotez, Jeffrey M Bethony

“…<h4>Conclusions</h4>Vaccination of hookworm-naïve adults with Na-GST-1/Alhydrogel plus CpG 10104 was safe and minimally reactogenic. Addition of CpG 10104 to Na-GST-1/Alhydrogel resulted in significant improvement in IgG responses against the vaccine antigen. …”
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Impact of the Smarter Safer Homes Solution on Quality of Life and Health Outcomes in Older People Living in Their Own Homes: Randomized Controlled Trial by Wei Lu, David Silvera-Tawil, Hwan-Jin Yoon, Liesel Higgins, Qing Zhang, Mohanraj Karunanithi, Julia Bomke, Joshua Byrnes, Jennifer Hewitt, Vanessa Smallbon, Jill Freyne, Deepa Prabhu, Marlien Varnfield

“…However, this difference did not persist at the 12-month assessment (mean difference 0.031, 95% CI –0.014 to 0.076; Cohen d=0.259). …”
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Pediatric Tuina for the treatment of functional dyspepsia: A systematic review and meta-analysis of randomized controlled trials by Na-Yeon Ha, Chang-Yul Keum, Jinsung Kim

“…The combined Tuina group demonstrated significantly lower overall dyspeptic symptom scores (standard mean difference (SMD) = -1.18, 95 % CI [-1.46, −0.91], p < 0.00001) and shorter times to resolution of primary symptoms, including abdominal distension (mean difference (MD) = -2.08, 95 % CI [-2.35, −1.81], p < 0.00001), abdominal pain (MD = −1.54, 95 % CI [-1.92, −1.17], p < 0.00001), belching (MD = −1.11, 95 % CI [-1.44, −0.77], p < 0.00001), and anorexia (MD = −1.37, 95 % CI [-1.67, −1.07], p < 0.00001). Additionally, the recurrence rate following treatment was significantly lower (RR = 0.32, 95 % CI [0.14, 0.72], p = 0.006). …”
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Analisis Komparatif Keamanan Aplikasi Pengelola Kata Sandi Berbayar Lastpass, 1Password, dan Keeper Berdasarkan ISO/IEC 25010 by Whisnu Yudha Aditama, Ira Rosianal Hikmah, Dimas Febriyan Priambodo

“…Meanwhile, the 1Password application is superior in proving the identity of the user as claimed and is able to log every user activity into a log. and the Lastpass application has the same advantages as Keeper application in the duration of keeping logs in the system. In addition, three applications have the same level of security in securing user data from unauthorized parties, and implement the use of digital signatures or certificates to prevent denial. …”
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Curcumin administration alleviates seminal vesicle damage in type 1 diabetic rats by promoting AQP8 expression through AR activation by Dawei Ni, Kun Liu, Ning Wu, Bin You, Baibing Yang, Wei Wu, Yutian Dai

“…The results revealed that the expression of AR and APQ8 in high glucose-treated seminal vesicle cells was decreased and that curcumin treatment upregulated the expression of AR and AQP8. After the addition of bicalutamide (an AR inhibitor), the expression of AQP8 was reduced. …”
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Associations between Prospective Memory, Executive Function and Physical Activity in Schoolchildren by Anouk Irina Glättli, Markus Gerber, Sebastian Ludyga

“…Journal of Lifestyle Medicine, 8(2), 51–59. https://doi.org/10.15280/jlm.2018.8.2.51 …”
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Design and Validation of Policy Making Model with Open Government Approach by Zahra Mohammadi, Abdolmajid Imani, Farahnaz Ahang

“…The successful implementation of open government was shown to have a significantly positive effect on the resulting outcomes of such initiatives. Additionally, it was confirmed with a 95% confidence level that the dimensions of open government positively and significantly correlate with the overall effectiveness of open government practices. …”
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Oncometabolite D-2HG drives tumor metastasis and protumoral macrophage polarization by targeting FTO/m6A/ANGPTL4/integrin axis in triple-negative breast cancer by Siyue Zhang, Ning Zhang, Tong Wan, Yinqiao He, Jie Hao, Yiwei Liu, Yidong Liu, Bing Chen, Wenjing Zhao, Lijuan Wang, Dan Luo, Chao Gao, Qifeng Yang

“…Notably, the knockdown of ANGPTL4 or treatment with GLPG1087 (an integrin antagonist) significantly reduced D-2HG-induced proliferation and metastasis in TNBC cells. Additionally, ANGPTL4 was found to promote macrophage M2 polarization within the tumor microenvironment via paracrine signaling, further driving TNBC progression. …”
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Phenotypic and genotypic characterization of clinical carbapenem-resistant Acinetobacter species harboring the metallo-beta-lactamases IMP-8 or NDM-1 in China by Qingye Xu, Xinli Mu, Jintao He, Haiyang Liu, Xiaochen Liu, Yanfei Wang, Xiaoting Hua, Yunsong Yu

“…All blaNDM-1 plasmids were transferable, and the blaNDM-1 genes were in a conservative region. Additionally, multiple resistance genes, including those conferring resistance to aminoglycosides, tetracyclines, and macrolides, were detected on plasmids from these strains. …”
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Identification of patient demographic, clinical, and SARS-CoV-2 genomic factors associated with severe COVID-19 using supervised machine learning: a retrospective multicenter study by Kuganya Nirmalarajah, Patryk Aftanas, Shiva Barati, Emily Chien, Gloria Crowl, Amna Faheem, Lubna Farooqi, Alainna J. Jamal, Saman Khan, Jonathon D. Kotwa, Angel X. Li, Mohammad Mozafarihashjin, Jalees A. Nasir, Altynay Shigayeva, Winfield Yim, Lily Yip, Xi Zoe Zhong, Kevin Katz, Robert Kozak, Andrew G. McArthur, Nick Daneman, Finlay Maguire, Allison J. McGeer, Venkata R. Duvvuri, Samira Mubareka

“…Notably, inpatients were older with a mean age of 66.67 years (SD ± 17.64 years), whereas outpatients had a mean age of 44.89 years (SD ± 16.00 years). SHapley Additive exPlanations (SHAP) analyses revealed that underlying vascular disease, underlying pulmonary disease, and fever were the most significant clinical features associated with hospitalization. …”
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Mechanism of warmed malate ringer’s solution in fluid resuscitation in improving the lethal triad of severe trauma by WU Yinyu, SHE Han, SHE Han, DU Yunxia, DU Yunxia

“…The changes of activated clotting time (ACT), reaction time (R), maximum amplitude (MA), and rate of blood clot formation (Angle) at different time points were detected by using thromboelastography, and tail bleeding, core body temperature and arterial blood gas parameters, were also observed and detected. …”
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Time-frequency characterization of acoustic emission signals from bending damage of corroded reinforced concrete beams in high- temperature saline environment by Dazhong Zhang, Shiyi Zhang, SM Chayan, Yingfang Fan, Surendra P. Shah, Junjie Zheng

“…The experimental results indicate that high-temperature conditions exacerbate the corrosion of the beam body compared to room-temperature conditions. Specifically, the corrosion rate of steel reinforcement increases by 2.25 %, and rust expansion cracks appear earlier under high-temperature conditions. …”
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UX Evaluation with Standardized Questionnaires in Ubiquitous Computing and Ambient Intelligence: A Systematic Literature Review by Ignacio Díaz-Oreiro, Gustavo López, Luis Quesada, Luis A. Guerrero

“…This work also aims to establish whether these questionnaires are combined with other evaluation instruments and with which complementary instruments are they used more frequently (RQ3). In addition, this review intends to determine how the three questionnaires have been applied in the fields of ubiquitous computing and ambient intelligence (RQ4) and also in studies that incorporate nontraditional interfaces, such as haptic, gesture, or speech interfaces, to name a few (RQ5). …”
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Computational analysis of Newtonian fluid in a 2-D square cavity with kinetic energy, enstrophy, and palinstrophy in the presence of bottom corner obstacle by Dalmalka Praveen Kumar, Yadagiri Rameshwar, Rifaqat Ali, S. Nazari, Mohamed Kallel, Ahmed M. Galal

“…However, excessive heights (H = 0.95L) suppress these vortices, creating stable but inefficiently mixed flow regimes. In addition, we discovered a new empirical relation among Pressure potential energy (PE) in three configurations for the steady-state solution and it can be generalised and holds for any positive reals H and W up to almost near 1L and 0.50L respectively. …”
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Efek Pemberian Vitamin C Terhadap Aktifitas Katalase Hati Tikus Galur Wistar yang Terpapar Ion Pb by Elmatris Sy, Husnil Kadri, Eti Yerizel

“…Penelitian ini bertujuan untuk mengetahui Efek Pemberian Vitamin C Terhadap Aktifitas Katalase Hati Tikus Galur Wistar Yang Terpapar Ion Pb, dilakukan di laboratorium Farmakologi Fakultas Farmasi dan Biokimia Fakultas Kedokteran Unand Penelitian dilakukan terhadap tikus galur wistar, berumur tiga bulan, berat badan + 200 gram, yang berjumlah 28 ekor. …”
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The effect of nursing care provided to coronary intensive care patients according to their circadian rhythms on sleep quality, pain, anxiety, and delirium: a randomised controlled... by Meryem Pelin, Havva Sert

“…Data were collected using “Patient Information Form, Sleep Quality Scale in Coronary Intensive Care Patients (SQ-CC), Visual Analogue Scale (VAS), Morningness-Eveningness Questionnaire (MEQ), Hospital Anxiety and Depression Scale (HADS), Intensive Care Delirium Screening Checklist (ICDSC).” In addition, melatonin and cortisol measurements were made, and sleep data were taken with a smartwatch. …”
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Candidate approaches for predicting vitiligo recurrence: an effective model and biomarkers by Binhao Liu, Jiacheng Shen, Jiayu Li, Bowen Tian, Bowen Tian, Bin Zhou, Jiachen Gui, Zhimin Li, Yue Zhang, Wenzhi Hu, Qiang Li, Qiang Li

“…Multivariate logistic regression model showed IFN-γ is an independent predictor for vitiligo recurrence [OR (95%CI) =1.051 (1.012~1.116)], with a prediction accuracy of 90.5% (38/42) on the training dataset and 88.9% (16/18) on the testing dataset.ConclusionPlasma IFN-γ, CXCL9, CXCL10, CXCL11 and IL-6 might be potential biomarkers for vitiligo recurrence, with CXCL9 also associated with disease activity. Additionally, multivariate logistic regression model demonstrated that IFN-γ is an independent predictor of vitiligo recurrence and the model could be a candidate approach for predicting vitiligo recurrence.…”
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The Effect of Dynamic Service Innovation Capabilities on Firm Performance: The Moderating Role of Perceived Environmental Dynamism and the Mediating Role of Service Innovation and... by Rasoul Nosratpanah, Samad Barani, Aref Ashrafzadeh, Gholamhosein Atashi

“…The findings also confirmed the mediating role of service innovation and competitive advantage. In addition, the moderating effect of perceived environmental dynamics on the relationship between dynamic service innovation capabilities and service innovation was confirmed. …”
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