In Vitro Cytotoxic Study and Detection of Apoptosis on Breast Cancer Cell lines MDA-MB 231 after Exposed to Azadirachta Indica A. Juss (neem) Extract by Dessy Arisanty

“…MDA-MB231 cell death elicited by the extract was found to be apoptotic in nature based the indication of nucleus condensation, shrinkage of nucleus membrane and also DNA fragmentation which are a hallmark of apoptosis. In addition, ultrastructural analysis also revealed apoptotic characteristics which are the presence of chromatin margination and apoptotic bodies in the extract-treated cells. …”
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Correlation between meteorological variables, air quality, and the Coronavirus-19 pandemic events by M. Gidarjati, T. Matsumoto

“…Air quality parameters were generally higher in the dry season. Throughout the pandemic, the temperature and wind speed exhibited a consistent pattern, remaining stable. …”
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Estimation of blue carbon stock in the Liaohe Estuary wetland based on soil thickness and multi-scenario modeling by Lina Ke, Nan Lei, Shilin Zhang, Changkun Yin, Yao Lu, Lei Wang, Qin Tan, Yu Zhao, Quanming Wang

“…The research analyzed the spatiotemporal distribution characteristics of land cover and blue carbon stock from 2000 to 2023. Additionally, the distribution of blue carbon stocks and their degradation and improvement were modeled for different scenarios in 2030. …”
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Effects of olive leaf extract on exercise performance and muscle mitochondrial response in young healthy adults by Clément Lanfranchi, Nadège Zanou, Jérôme Feige, Umberto DeMarchi, Aurélie Hermant, Ornella Cominetti, Eugenia Migliavacca, Alba Moreno-Asso, Astrid Hostrman, Sara Mistro, Nicolas Place

“…Cell Metabolism. https://doi.org/10.1016/j.cmet.2024.10.021 …”
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Pan-cancer analysis of the transcriptional expression of histone acetylation enzymes in solid tumors defines a new classification scheme for gliomas by Junhao Zhang, Lingbo Li, Aiwei Tang, Chucheng Wang, Yupeng Wang, Yongqi Hu, Guangting He, Guangting He, Wangjun Liao, Wangjun Liao, Wangjun Liao, Rui Zhou

“…However, systematic characterization of the transcriptomic landscape and clinical relevance of HATs and HDACs in pan-cancer contexts remains lacking.MethodsTranscriptome and clinical data of 9,483 patients across 31 tumor types from The Cancer Genome Atlas were collected for systematic pan-cancer analysis. Additional glioma-specific datasets (Chinese Glioma Genome Atlas, GlioVis, GSE43378, and GSE182109) were also collected to validate the transcriptional characteristics of HATs and HDACs in gliomas. …”
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Voacanga africana-artesunate and Voacanga africana-amodiaquine combinations as effective anti-plasmodial agents in mice by Daniel Ampomah Frimpong, Aliu Moomin, Samuel Asare Nkansah, Aaron Opoku Antwi, Abubakar Ibn Sidik, Paa Kofi Tawiah Adu-Gyamfi, Kwesi Boadu Mensah

“…Conclusions: VA showed a moderate antimalarial activity when used in monotherapy, while a combination of VA and AT showed synergism against P. beighei infection by reducing parasitemia levels, preventing hemolysis, decreasing PCV, increasing body temperature and increasing body weights. However, a combination of voacanga seed oil and amodiaquine demonstrated an antagonistic effect.…”
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Beyond LDL cholesterol: remnant cholesterol is associated with cardiometabolic risk factors in children by Ana Torres-Costoso, Vicente Martínez-Vizcaíno, Andreia Oliveira, Mairena Sánchez-López, Eva Rodríguez-Gutiérrez, Sergio Núñez de Arenas-Arroyo, Montserrat Solera-Martínez, Blanca Notario-Pacheco, Vanessa Martínez-Madrid, Arthur Eumann Mesas

“…Results Children in the high-RC subgroups, specifically those with low LDL-c/high RC and high LDL-c/high RC, presented significantly greater insulin levels and WC than did their peers in the low-RC subgroups. RC was more strongly associated with cardiometabolic risk factors than LDL-c (insulin β = 2.073/ − 0.026; HOMA-IR β = 0.451/ − 0.002; MAP β = 1.214/0.300; WC β = 2.842/1.058; and CRF β = − 0.316/ − 0.194 for RC and LDL-c, respectively). …”
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An efficient method for predicting the morphology of proppant packs based on a surrogate model by Tao ZHANG, Hangyu ZHOU, Yifan ZHANG, Jianchun GUO, Haoran GOU, Tang TANG

“…For the displacement-height model, although the predicted placement profile lacked detailed irregularities of the proppant accumulation surface because of model simplification, it accurately described the characteristic variation in placement morphology with changes in injection rate, demonstrating that the surrogate model for predicting particle placement height can also efficiently capture the proppant placement morphology within the fracture. Additionally, the time consumed by a single prediction step was only 0.14% of the time consumed by a single simulation step. …”
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Factors associated with the discontinuation of modern contraceptive methods among lactating women in nine West African high-fertility countries: findings of the most recent demogra... by Abou Coulibaly, Adama Baguiya, Denise Kpebo, Augustin Zango, Halima Tougri, Franck Garanet, Seni Kouanda

“…Women were more likely to discontinue contraception if they were the head of the household (adjusted prevalence ratio (aPR) = 1.71; 95% CI [1.17–2.50]; p = 0.006). In addition, compared to implant users, women using pills (aPR = 3.06; 95% CI [2.24–4.16]; p < 0.001), those using injectables (aPR = 2.80; 95% CI [2.16–3.62]; p < 0.001), and women whose partners used condoms (aPR = 2.30; 95% CI [1.47–3.59]; p < 0.001) were more likely to discontinue contraception. …”
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The association of visceral and subcutaneous fat areas with phenotypic age in non-elderly adults, mediated by HOMA-IR and HDL-C by Yuanhong Liu, Min Xu, Liqing Wang, Linyun Meng, Mengran Li, Shumin Mu

“…Additionally, subgroup analysis was used to identify variations in population characteristics. …”
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A Model H5N2 Vaccine Strain for Dual Protection Against H5N1 and H9N2 Avian Influenza Viruses by Jin-Ha Song, Seung-Eun Son, Ho-Won Kim, Se-Hee An, Chung-Young Lee, Hyuk-Joon Kwon, Kang-Seuk Choi

“…To enhance the immunogenicity of the recombinant H5N2 vaccine strain, N-glycans of the HA2 subunit, NA, and M2e were modified. Additionally, we replaced M2e with avian M2e to enhance the antigenic homogeneity of AIVs for better protection. …”
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Utilization of biofloc meal as a feed ingredient for Nile tilapia and common carp by Julie Ekasari, Hilda Kemala Pasha, Nur Bambang Priyoutomo

“…Nile tilapia and common carp juveniles with an initial average body weight of 11.72±0.04 g and 8.81±0.04 g, respectively, were used as the experimental animals. …”
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Spatial characteristics and health risks assessments of trace metal pollution from road dusts in the industrialized city of Bangladesh by Masum Howlader, Ashik Md Mamun, Mohammad Mahfuzur Rahman, Md Hasibur Rahman, Sadhon Chandra Swarnokar, Mahfuza Sultana, Md Tanvir Rahman, Tusar Kumar Das

“…The infant's cancer risk for Cd (1.66−05) and Cr (1.59−04) is very close to the upper limit (10−4 to 10−6). Additional protective measures ought to be contemplated to diminish exposure to road dust among adults and infants.…”
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Management of mangrove landscape and ecosystem for ecotourism by H.T. Silalahi, M. Basyuni, E.Y. Aritonang, B. Slamet, K.S. Hartini, A. Wee

“…Furthermore, the analysis of strengths, weaknesses, opportunities, and threats revealed that the improvement of mangrove ecosystem management, the addition of supporting facilities, and the provision of environmental and conservation education to tourists can contribute to the enhancement of ecotourism.CONCLUSION: Ecotourism plays a crucial role in preserving the sustainability of the mangrove ecosystem while also influencing socio-economic factors. …”
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Comprehensive health assessment of retired martial arts athletes: bone density, dietary intake, physical activity, and wellbeing by Tasneem Alshaer, Nihad Battikhi, Adam Tawfiq Amawi, Khalid Trabelsi, Khalid Trabelsi, Haitham Jahrami, Haitham Jahrami, Philippe Bouedo, Hadeel Ali Ghazzawi

“…The differences were explored in weight changes, bone density, quality of life, happiness, stress, insomnia, physical activity, and dietary intake to understand how martial arts impact these health dimensions.MethodsA descriptive case-control study was conducted among 30 retired male elite athletes and 20 age-matched non-athletes. Bone density and body composition were measured using dual-energy X-ray absorptiometry (DEXA) scans. …”
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Sensory acceptability of buffalo meat compared to beef by Luis A. de la Cruz-Cruz, Cristian Larrondo-Cornejo, Patricia Roldán-Santiago, René Rodríguez-Florentino

“…However, they noted that buffalo meat was like select beef (71%/n=54). Additionally, 47% (n=36) indicated that “maybe” they could include buffalo meat in their diets, followed by 37% (n=28) who indicated that “yes” they would include buffalo meat at least once or twice a week. …”
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A Dynamic Adaptive Ensemble Learning Framework for Noninvasive Mild Cognitive Impairment Detection: Development and Validation Study by Aoyu Li, Jingwen Li, Yishan Hu, Yan Geng, Yan Qiang, Juanjuan Zhao

“…MethodsWe recruited 843 participants aged 60 years and older from the geriatrics and neurology departments of our collaborating hospitals, who were randomly divided into a development dataset (674/843 participants) and an internal test dataset (169/843 participants) at a 4:1 ratio. In addition, 226 older adults were recruited from 3 external centers to form an external test dataset. …”
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The clinical prediction model to distinguish between colonization and infection by Klebsiella pneumoniae by Xiaoyu Zhang, Xifan Zhang, Deng Zhang, Jing Xu, Jingping Zhang, Xin Zhang

“…“Admitted with a diagnosis of respiratory infectious disease” (8.39) was identified as the most important factor in the model, followed by “Hypoalbuminemia” (7.83), then “ESBL” (7.06), “Electrolyte Imbalance” (5.81), “Age &gt; 62 years” (5.24), “The number of Positive Sputum Cultures for KP &gt; 2” (4.77), and being bedridden (4.24). Additionally, invasive procedures (such as history of tracheostomy, use of ventilators for &gt;96 h, and craniotomy) were also significant predictive factors. …”
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Acceptability of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine plus dihydroartemisinin-piperaquine in Papua New Guinea: a qualitative stu... by Elvin Lufele, Sophie Pascoe, Alice Mengi, Alma Auwun, Nalisa Neuendorf, John W. Bolnga, Moses Laman, Stephen J. Rogerson, Kamala Thriemer, Holger W. Unger

“…There was a high perceived effectiveness of SP plus DP; most women reported that they did not get malaria or felt sick during pregnancy. …”
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Pengembangan Auto-AI Model Generatif Analisis Kompleksitas Waktu Algoritma Untuk Data Multi-Sensor IoT Pada Node-RED Menggunakan Extreme Learning Machine by Imam Cholissodin, Dahnial Syauqy, Dwi Ady Firmanda, Ibrahim Aji, Edy Rahman, Syazwandy Harahap, Fernando Septino

“…Langkah dalam penelitian digunakan pembuatan model generatif berbasis algoritma Extreme Learning Machine (ELM) berdasarkan pencatatan nilai waktu komputasi pada beberapa kali pengujian untuk mengotomasi penentuan model persamaan kompleksitas waktu algoritma secara general baik untuk pencarian best case, worst case maupun average case untuk non-rekursif, dan base case dan recurrent case untuk rekursif, maupun keduanya. …”
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