Whether Detection of Gene Mutations Could Identify Low- or High-Risk Papillary Thyroid Microcarcinoma? Data from 393 Cases Using the Next-Generation Sequencing by Lei Jin, Liang Zhou, Jian-Biao Wang, Li Tao, Xiao-Xiao Lu, Na Yan, Qian-Ming Chen, Li-Ping Cao, Lei Xie

“…Our data showed that gene mutations did not appear to have much to do with high-risk papillary thyroid microcarcinoma (PTMC). …”
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Role of stability analysis and waste discharge concentration of ternary hybrid nanofluid in a non-Newtonian model with slip boundary conditions by Nurhana Mohamad, Shuguang Li, Umair Khan, Anuar Ishak, Ali Elrashidi, Mohammed Zakarya

“…The magnetic parameter enlarges shear stress with the help of the Lorentz force but thermal radiation increases the heat transfer rate while reducing surface drag. Additionally, nanoparticle volume fractions and the porous medium elevate shear stress and heat transfer rate. …”
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DepITCM: an audio-visual method for detecting depression by Lishan Zhang, Lishan Zhang, Zhenhua Liu, Yumei Wan, Yunli Fan, Diancai Chen, Qingxiang Wang, Kaihong Zhang, Yunshao Zheng

“…However, there are still some limitations in the currently proposed deep models based on audio-video data, for example, it is difficult to effectively extract and select useful multimodal information and features from audio-video data, and very few studies have been able to focus on three dimensions of information: time, channel, and space at the same time in depression detection. In addition, there are challenges in utilizing other tasks to enhance prediction accuracy. …”
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The predictive value of the serum creatinine-to-albumin ratio (sCAR) and lactate dehydrogenase-to-albumin ratio (LAR) in sepsis-related persistent severe acute kidney injury by Xiaoxiao Luo, Dongyang Liu, Cuicui Li, Jia Liao, Wuyang Lv, Yuchen Wang, Ruxue Diao, Yingyu Jin

“…The model's predictive ability for secondary outcomes, such as renal replacement therapy (RRT), also improved with the addition of the Log(sCAR)_Log(LAR) score. The sensitivity analysis further corroborated the stability of the Log(sCAR)_Log(LAR) score in predicting persistent severe SA-AKI and secondary outcomes, such as RRT. …”
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Extracellular vesicles from fifth-stage larval Angiostrongylus cantonensis upregulate cholesterol biosynthesis and suppress NLRP2-associated inflammatory responses in mouse astrocy... by Chien-Ju Cheng, Lian-Chen Wang, Lichieh Julie Chu, Kuang-Yao Chen, Ching-Yun Huang, Kuo-Lun Lan, Kuo-Yang Huang

“…The highly abundant proteins in L5 EVs that have immunomodulatory or pathogenic potential in the host deserve further investigation. Additionally, the uptake of L5 EVs by mouse astrocytes significantly upregulates cholesterol synthesis and suppresses ATP-induced NLRP2 inflammasome-related signaling. …”
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Scale brightness of common goldfish on diet supplemented with seaweed Sargassum sp. and pumpkin Cucurbita moschata by Irfina Manda Astari, Tri Rima Setyawati, Ari Hepi Yanti

“…The results of ANOVA test showed that the Sargassum sp. and pumpkin mill addition on food significantly improved of scales brightness of  common goldfish. …”
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Detecting Deception and Ensuring Data Integrity in a Nationwide mHealth Randomized Controlled Trial: Factorial Design Survey Study by Krista M Kezbers, Michael C Robertson, Emily T Hébert, Audrey Montgomery, Michael S Businelle

“…Completing multiple prescreeners (301/501, 60.1%) and providing invalid addresses (156/501, 31.1%) were the most common reasons prescreeners were flagged. An additional 1% (18/1928) of prescreeners were flagged as potentially deceptive during the subsequent study screening and enrollment phone call. …”
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Modeling Lake Titicaca's water balance: the dominant roles of precipitation and evaporation by N. Lima-Quispe, D. Ruelland, A. Rabatel, W. Lavado-Casimiro, T. Condom

“…Previous estimates for this lake have relied on scaling factors to close the water balance, which introduces additional uncertainty. This study presents an integrated modeling framework based on conceptual models to quantify natural hydrological processes and net irrigation consumption. …”
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MAZ-mediated tumor progression and immune evasion in hormone receptor-positive breast cancer: Targeting tumor microenvironment and PCLAF+ subtype-specific therapy by Gaofeng Ni, Yuwei Sun, Hongling Jia, Zhikai Xiahou, Yumeng Li, Fu Zhao, Hongyan Zang

“…C3 PCLAF+ tumor cells subtype was found to be closely associated with cancer-associated fibroblasts through the MK signaling pathway, facilitating tumor progression. Additionally, we discovered that MAZ was significantly expressed in C3 PCLAF+ tumor cells subtype, and in vitro experiments confirmed that MAZ knockdown inhibited tumor growth, accentuating its underlying ability as a therapeutic target. …”
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Predicting Iran Cooperative Development Bank's Profit/Loss: Two-stage Collective Learning by Seyed Bagher Fattahi, Seyed Mozafar Mirbargkar, Ebrahim Chirani, Mohammadreza Vatanparast

“…The results reveal notably high-performance accuracy, evidenced by an MAE metric of 5.66 and an MSE metric of 620.34. Additionally, the correlation between training data and predictions from the two-stage collective machine learning stands at 0.9977. …”
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A broad assessment of forty-one skin phenotypes reveals complex dimensions of skin ageing by Jun Yan Ng, Qi Yi Ambrose Wong, Jun Jie Lim, Dingyu Cen, Jia Yi Karen Wong, Yi Ying Eliza Lim, Yang Yie Sio, Kavita Reginald, Yee-How Say, Fook Tim Chew

“…Conclusions We presented clear evidence that skin ageing is much more than just wrinkles, pigmentation and photo-ageing. The addition of telangiectasia, poor lip fullness, a lighter skin colour, xerosis, ephelides, ptosis of eyelids, eyebags, and a low eyebrow positioning added more dimensions to skin ageing phenotype presentations.…”
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Environmental Life Cycle Assessment of Healthcare Waste Valorisation Alternatives by Zlaugotne Beate, Zandberga Anda, Gusca Julija, Kalnins Silvija Nora

“…From textile recycling acoustic panels (VS5) with result 55 Pt and 598 kg CO2 eq for global warming impact category and reinforced cement (VS2) with result 55 Pt and 603 kg CO2 eq for global warming impact category. Therefore, additional scenario was created where plastic, textile and residual iHCW streams are fully recycled and fully eliminating landfilling. …”
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Development of an artificial intelligence-based application for the diagnosis of sarcopenia: a retrospective cohort study using the health examination dataset by Chang-Won Jeong, Dong-Wook Lim, Si-Hyeong Noh, Sung Hyun Lee, Chul Park

“…These models were used to identify L3 slices from abdominal computed tomography images and divide the images into the three-segmented domains for sarcopenia diagnosis. Additionally, we developed an algorithm for the calculation of T-Score calculated as (measurement value-Young adult mean)/(Young adult SD) using the Aggregation Pipeline by MongoDB, with the mean and standard deviation for skeletal muscle area (SMA), SMA/height2, SMA/weight, and SMA/body mass index (BMI) for both sexes and different age groups. …”
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Single-Cell Transcriptome Analysis Reveals Different Immune Signatures in HPV- and HPV + Driven Human Head and Neck Squamous Cell Carcinoma by Simin Li, Yang Wang, Rui Sun, Debora Franceschi, Hongying Pan, Chenxuan Wei, Anthony Chukwunonso Ogbuehi, Bernd Lethaus, Vuk Savkovic, Sebastian Gaus, Rüdiger Zimmerer, Dirk Ziebolz, Gerhard Schmalz, Xiao Jiang

“…Cell-cell interactions were analyzed with CellChat R package. Additionally, cell-cell communication patterns in key signal pathways were compared in different tissue groups. …”
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Asiaticoside Attenuates Chronic Restraint Stress-Induced Hippocampal CA1 Neuronal Ferroptosis via Activating BDNF/Nrf2/GPX4 Signaling Pathway by Zhou A, Feng HY, Fan CN, Wang J, Yuan ZY, Xu GH, Li CF, Huang WF, Yi LT

“…At the molecular level, asiaticoside enhanced the expression of brain-derived neurotrophic factor (BDNF), phosphorylated tropomyosin receptor kinase B (pTrkB), phosphorylated nuclear factor erythroid 2-related factor 2 (pNrf2), glutathione peroxidase 4 (GPX4), and solute carrier family 7 member 11 (SLC7A11), indicating its neuroprotective and antioxidative effects. In addition, asiaticoside suppressed the expression of ferroptosis markers, including ferritin light chain (FLC) and transferrin receptor only in CA1 region. …”
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Agronomic characteristics, mineral nutrient content, antioxidant capacity, biochemical composition, and fatty acid profile of Iranian pistachio (Pistacia vera L.) cultivars by Ali Khadivi, Mohammadali Nikoogoftar-Sedghi, Yazgan Tunç

“…Conclusions The findings obtained in this study allow producers to select the most suitable cultivars for obtaining more efficient and high-quality products. Additionally, choosing cultivars based on environmental factors and market demands contributes to the development of more effective production strategies. …”
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Impact of school salad bars on fruit and vegetable selection, intake, and waste in Mid-Atlantic elementary schools by Melanie K. Bean, Suzanne E. Mazzeo, Lilian de Jonge, Laura Thornton, Hollie Raynor, Ashley Mendoza, Sarah Farthing, Bonnie Moore

“…Additional efforts are needed to increase vegetable intake and minimize fruit waste from salad bars. …”
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Effects of Honey Supplementation in Female Brood Feed on Male and Female Percentages, Growth, and Survival Rate of Crayfish Red Claw (Cherax quadricarinatus) Seed by Akhmad Taufiq Mukti

“…The treatments that was applied were addition of honey dosages in female brood feed of crayfish red claw, i.e. 0 (control), 50, 100, 150, 200, 250 and 300 ml/kg feed. …”
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Association between weight-adjusted-waist index and long-term prognostic outcomes in cardiovascular disease patients: results from the NHANES 1999–2018 study by Hanbin Li, Wen Zhong, Hongxin Cheng, Shiqi Wang, Ran Li, Lu Wang, Chengqi He, Quan Wei

“…WWI (cm/√kg) is a continuous variable and calculated as waist circumference (WC, cm) divided by square root of body weight (kg). For analysis purposes, the participants were divided into four groups based on the quartiles (Q1 – Q4) of the WWI. …”
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Insights into simulation-based learning: student and faculty experiences in a PharmD program in Saudi Arabia by Reem Binsuwaidan, Najla A. Altwaijry, Alnada A. Ibrahim, Rawan A. Alghamdi, Razan Bin Humaid, Alaa A. AlSharif, Alaa A. AlHubaishi, Elshaymaa I. Elmongy, Lina I. Alnajjar, Ghadah H. Alshehri

“…Student responses to computerized simulations were positive for perceived learning outcome acquisition (4.16 ± 0.844), preparedness (4.14 ± 0.892), and general perception (4.11 ± 0.951). Additionally, students reported positive perceived learning outcome acquisition (4.44 ± 0.680), preparedness (4.40 ± 0.717), and general perception (4.46 ± 0.676) for standardized patient role-play. …”
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