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53601
Hippocampal Functional Radiomic Features for Identification of the Cognitively Impaired Patients from Low-Back-Related Pain: A Prospective Machine Learning Study
Published 2025-01-01“…Finally, we further analyzed the relationship between the hippocampal functional radiomic features and clinical measures, to explore the clinical significance of these features.Results: The combined radiomic features model logistic regression algorithm superior performance in distinguishing cognitively impaired patients from LBLP (AUC = 0.970, accuracy = 92.3%, sensitivity = 92.3%, specificity = 92.3%) compared to the other models. Additionally, radiomic wavelet features were correlated with Montreal Cognitive Assessment (MoCA) and Hamilton Anxiety Scale, present pain intensity scores in cognitively impaired LBLP patients (P < 0.05, with Bonferroni correction).Conclusion: Hippocampal functional radiomic features are valuable for diagnosing cognitively impaired patients from LBLP.Keywords: cognitive impairment, resting-state functional MRI, low-back-related leg pain, radiomic, logistic regression algorithm…”
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53602
Prevalence and associated factors of malaria among the displaced population in refugee camps in Africa: a systematic review and meta-analysis
Published 2025-01-01“…Methods This review adhered to PRISMA standards, involving searches across electronic data bases such as Google Scholar, PubMed, Web of Science, Scopus, and Science Direct. In addition, grey literature was retrieved from several professional associations. …”
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53603
Combinatorial functionomics identifies HDAC6-dependent molecular vulnerability of radioresistant head and neck cancer
Published 2025-01-01“…Abstract Background Radiotherapy is the primary treatment modality for most head and neck cancers (HNCs). Despite the addition of chemotherapy to radiotherapy to enhance its tumoricidal effects, almost a third of HNC patients suffer from locoregional relapses. …”
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53604
Association between moderate-to-vigorous physical activity trajectories and academic achievement in Chinese primary school children: a 3-year longitudinal study
Published 2025-01-01“…The High MVPA group exhibited significant score increases in reading (β = 11.3, 95% CI: 7.93–14.67), mathematics (β = 12.32, 95% CI: 9.61–15.02), and language (β = 11.53, 95% CI: 8.99–14.06). Additionally, notable gender differences in MVPA trajectories were observed, and a positive association was found between favorable sports attitudes and improved academic achievement. …”
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53605
Evaluation of ecological geological environment carrying capacity and analysis of driving mechanisms based on normal cloud model and geodetector model
Published 2025-01-01“…Overall, this study provides essential guidance for formulating ecological protection and restoration plans for the national territorial space in the Luoyang area of the YRB. Additionally, the evaluation methods established in this study have promotional value and can serve as a reference for the ecological geological spatial management of other resource-based cities.…”
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53606
A Novel Multiplex LAMP Assay for the Rapid and Accurate Diagnosis of Visceral Leishmaniasis Caused by Leishmania infantum from Iran
Published 2023-01-01“…Various approaches were applied to interpret the multiplex LAMP reaction which deciphered a higher sensitivity when compared to the RT-qPCR for L. infantum (one copy number of plasmid, equal to 0.85 femtograms (fg) of plasmid concentration, and 0.004 parasite DNA per μL) detection while these three standard strains of Leishmania were confirmed to contain 40 DNA copies using RT-qPCR. Additionally, the multiplex LAMP detection limit was approximately equivalent to RT-qPCR for L. major and L. tropica, which included 0.342 picograms (pg) and 342 femtograms (fg) of plasmid concentration, 4 × 103 and 4 × 102 copy number of plasmid, and 17.1 and 1.71 parasite DNA per μL for L. major and L. tropica, respectively. …”
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53607
Evaluasi User Experience Aplikasi “J-KOPI (Jember Kota Pintar)” Menggunakan Metode Survei Dengan User Experience Questionnaire Dan User Interview
Published 2023-12-01“… Aplikasi J-KOPI (Jember Kota Pintar) merupakan aplikasi yang dikembangkan oleh DISKOMINFO Pemkab Jember. …”
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53608
Klasifikasi Mutu Telur Burung Puyuh Berdasarkan Warna dan Tekstur Menggunakan Metode K-Nearest Neighbor (KNN) dan Fusi Informasi
Published 2021-10-01“…From the research results, it is concluded that the system was managed to classify egg quality as good, medium, and bad with an accuracy of 77,78%. In addition, the classification with information fusion was able to outperform the classification without information fusion by 11.11% at the same value of 7 and information fusion is also able to accelerate classification process by 0.22 seconds compared to that of without information fusion. …”
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53609
Changes in Physical Activity Across Cancer Diagnosis and Treatment Based on Smartphone Step Count Data Linked to a Japanese Claims Database: Retrospective Cohort Study
Published 2025-01-01“…We applied a generalized additive mixed model with a cubic spline to describe changes in step counts before and after diagnosis. …”
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53610
Plasma circulating cell–free DNA integrity and relative telomere length as diagnostic biomarkers for Parkinson’s disease and multiple system atrophy: a cross-sectional study
Published 2025-12-01“…Specifically, higher cell-free DNA integrity was associated with increased risk of Parkinson’s disease (odds ratio [OR]: 5.72; 95% confidence interval [CI]: 1.54–24.19) and multiple system atrophy (OR: 10.10; 95% CI: 1.55–122.98). …”
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53611
Rare and syndromic tumours in South African children: A novel report from Sub-Saharan Africa
Published 2025-01-01“…Most require definitive surgical treatment; others required the addition of adjuvant chemotherapy and radiation. Overall, although lower than that reported in higher income countries, the prognosis of these tumours remains good. …”
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53612
Petrophysical assessment of the Hammam Faraun, Matulla and Nubia Reservoirs in the Ashrafi Oil Field, Gulf of Suez
Published 2025-01-01“…The findings underline the potential of these formations as significant contributors to the region’s hydrocarbon resources, emphasizing the necessity for ongoing exploration and development efforts. Additionally, the insights gained from this research can facilitate the implementation of advanced recovery techniques, ensuring the efficient utilization of hydrocarbon resources while addressing the challenges associated with reservoir management in the Gulf of Suez region and the Red sea.…”
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53613
A Study of Combined Onabotulinumtoxin A and Hyaluronic Acid Filler for the Treatment of Enlarged Facial Pores
Published 2025-01-01“…The most common adverse events were erythema, bruising, and edema, which were more frequent on the combination side. Additionally, 18 subjects (56.25%) experienced a palpable lump on the combination side, which resolved in most cases within a few months. …”
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53614
Grid-Scale Battery Systems for VAR Support in Con Edison Distribution Substations via Bi-Directional Smart Inverters
Published 2025-01-01“…Various scenarios were examined to ascertain the optimal inductive filter size that balances the BESS’s real and reactive power outputs. Additionally, simulations incorporating real-world grid elements at the substation were performed, including an evaluation of the combined effects of BESS VAR support with substation capacitor banks and shunt reactors. …”
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53615
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53616
Human rights violations are associated with forcibly displaced population’s mental health—a systematic review and meta-analysis
Published 2025-01-01“…Objective: The objectives of this systematic review are to examine: (1) the prevalence of mental health conditions among forcibly displaced persons; (2) to investigate methodological factors contributing to mental health conditions; and (3) associations between mental health conditions and human rights violations.MethodsWe conducted a systematic review with meta-analyses on the prevalence of anxiety, depression, and posttraumatic stress disorder among forcibly displaced populations and factors contributing to it by searching in databases MEDLINE (Ovid), Embase, Web of Science Core Collection (Clarivate), PsycINFO (EBSCO), Sociological Abstracts (ProQuest), and PTSDPubs (ProQuest). Additionally, we assessed the Global Peace Index. Pooled associations were calculated using a random-effects meta-analysis model. …”
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53617
Spatial and social relevance perceptions by pre-service teachers of learning about oil palm management as a local or nonlocal socioscientific issue
Published 2025-01-01“…This study investigated how local, national, and global subdimensions of spatial relevance as well as individual, societal, and professional subdimensions of social relevance influence PST' relevance perceptions of learning about SSI. Additionally, we examined how relevance perceptions vary depending on whether the SSI is local or nonlocal to PST. …”
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53618
From Peril to Protection: an evaluation of regulations impacting eScooter injuries
Published 2025-02-01“…After February 2022 restrictions, the rate precipitously declined with a median of two (p=0.033), reflecting an additional 60% decrease in injured patients.Conclusion Local advocacy resulting in increased safety regulations was associated with a significant reduction in injured patients secondary to eScooter use. …”
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53619
Triglyceride-glucose index predicts adverse cardiovascular events in patients with H-type hypertension combined with coronary heart disease: a retrospective cohort study
Published 2025-01-01“…C-statistics, NRI, and IDI were used to evaluate the incremental predictive ability of the TyG index. …”
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53620
Identification of Differentially Expressed Genes in Metastatic and Non-Metastatic Nasopharyngeal Carcinoma Cells by Suppression Subtractive Hybridization
Published 2005-01-01“…The molecular mechanism underlying the metastasis of nasopharyngeal carcinoma remains poorly understood, however, and requires additional elucidation. The aim of this study was to explore possible NPC gene candidates that may play key roles in NPC metastasis. …”
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