The Role of Rotational Thromboelastometry in Early Detection of the Hemostatic Derangements in Neonates with Systemic Candida Infection by Rozeta Sokou, Alexia Eleftheria Palioura, Aikaterini Konstantinidi, Alexandra Lianou, Maria Lampridou, Martha Theodoraki, Daniele Piovani, Stefanos Bonovas, Konstantina A. Tsante, Petros Ioannou, Nicoletta Iacovidou, Andreas G. Tsantes

“…Specifically, neonates with SCI had significantly prolonged clotting time (CT) and clot formation time (CFT), as well as lower clot amplitude at 10 min (A10) and maximum clot firmness (MCF) when compared to healthy neonates (<i>p</i> values < 0.05), findings that remained consistent after adjusting for confounding factors such as gestational age, birth weight, and sex. In addition, a strong correlation was noted between ROTEM parameters and disease severity based on the modified NEOMOD, nSOFA, and NeoBAT scores. …”
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Sustainable Skincare Innovation: Cork Powder Extracts as Active Ingredients for Skin Aging by Ana Silva, Cláudia Pinto, Sara Cravo, Sandra Mota, Liliana Rego, Smeera Ratanji, Clara Quintas, Joana Rocha e Silva, Carlos Afonso, Maria Elizabeth Tiritan, Honorina Cidade, Teresa Cruz, Isabel F. Almeida

“…The aqueous extract from P1 powder was especially active in reducing pro-inflammatory mediators, namely the <i>Nos2</i> gene, inducible nitric oxide protein levels, and nitric oxide production. Moreover, it did not induce skin irritation, as assessed by the EpiSkin test, in compliance with the OECD Test Guidelines. …”
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Evaluation of the Sterile Insect Technique for the Control of the Melon Fly (<i>Bactrocera cucurbitae</i>) Under Laboratory and Semi-Field Conditions in Sri Lanka by Muditha Nawarathne, Lahiru Udayanga, Hasini Ekanayake, Bader Alhafi Alotaib, Ananda Pathirage, Nayana Siriwardena, Athula Jayarathne, Hassan Ammouneh, Mohamed M. M. Najim, Abou Traore, Tharaka Ranathunge

“…The effect of irradiation on selected performance parameters such as survival, flight ability, fecundity, fertility, and adult longevity was evaluated under laboratory conditions. In addition, mating competitiveness was evaluated for irradiated male <i>B. cucurbitae</i>. …”
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Late-stage diversification strategy for the synthesis of peptide acids and amides using hydrazides by Shoko Tanaka, Mizuki Kanno, Yosuke Tashiro, Tetsuo Narumi, Nobuyuki Mase, Kohei Sato

“…Azidation of hydrazides using sodium nitrite (NaNO2) under acidic conditions, followed by the addition of β-mercaptoethanol (BME), could also be used to generate carboxylic acids. …”
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The use and subjective experience of sleep apps and their relationship with personality characteristics among young adults by Ståle Pallesen, Ståle Pallesen, Øystein Vedaa, Øystein Vedaa, Erlend Sunde, Erlend Sunde, Anette Harris, Siri Waage, Siri Waage, Ingvild West Saxvig, Jiewen Zhang, Bjørn Bjorvatn, Bjørn Bjorvatn

“…The survey included questions about demographics, morningness (Horne–Östberg Morningness–Eveningness Questionnaire-reduced scale), insomnia symptoms (Bergen Insomnia Scale), personality (HEXACO: Honesty-Humility, Emotionality, Extraversion, Agreeableness, Conscientiousness, and Openness to Experience), in addition to sleep app usage and how such use is experienced. …”
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Microtubule inhibition as a proposed mechanism for the anthelmintic effect of phytochemicals isolated from Cicerbita alpina by Mark James Horgan, Ines Sigg, Ioanna Poulopoulou, Francisco J. Rodriguez-Mejias, Eva Albertini, Pietro Fusani, Florian Fischer, Eftychia Martinidou, Daniela Schuster, Stefan Martens, Pidder Jansen Dürr, Matthias Gauly, Hermann Stuppner, Alexander Weiss, Veronika Temml, Bianka Siewert

“…., eggs, worms) of helminths. Additionally, the BuOH fraction was non-cytotoxic to human cell-lines. …”
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Comparing Antibody Responses to Homologous vs. Heterologous COVID-19 Vaccination: A Cross-Sectional Analysis in an Urban Bangladeshi Population by Kazi Istiaque Sanin, Mansura Khanam, Azizur Rahman Sharaque, Mahbub Elahi, Bharati Rani Roy, Md. Khaledul Hasan, Goutam Kumar Dutta, Abir Dutta, Md. Nazmul Islam, Md. Safiqul Islam, Md. Nasir Ahmed Khan, Mustufa Mahmud, Nuzhat Nadia, Fablina Noushin, Anjan Kumar Roy, Protim Sarker, Fahmida Tofail

“…However, the duration since the last booster dose was significantly associated with antibody levels, where each additional month since receiving the booster corresponded to approximately a 15–16% reduction in antibody levels (Adj. coeff: 0.85, 95% CI: 0.81, 0.88; <i>p</i> < 0.001). …”
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Thresholds for Rural Public and Ecosystem Services: Integration into Rural Green Space Spatial Planning for Sustainable Development by Huiya Yang, Jiahui Zou, Chongxiao Wang, Renzhi Wu, Maroof Ali, Zhongde Huang, Hongchao Jiang, Fan Zhang, Yang Bai

“…The results are as follows (1) With the increase in RPSs, all ESs respond with a downward trend. (2) In addition to the negative linear relationship between education and social welfare services and ESs, the response thresholds of other RPSs and ESs were identified. (3) According to multiple density threshold analysis of each RPS’s response to ESs, four functional areas were obtained. …”
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Enhancing individual glomerular filtration rate assessment: can we trust the equation? Development and validation of machine learning models to assess the trustworthiness of estima... by Antoine Lanot, Anna Akesson, Felipe Kenji Nakano, Celine Vens, Jonas Björk, Ulf Nyman, Anders Grubb, Per-Ola Sundin, Björn O. Eriksen, Toralf Melsom, Andrew D. Rule, Ulla Berg, Karin Littmann, Kajsa Åsling-Monemi, Magnus Hansson, Anders Larsson, Marie Courbebaisse, Laurence Dubourg, Lionel Couzi, Francois Gaillard, Cyril Garrouste, Lola Jacquemont, Nassim Kamar, Christophe Legendre, Lionel Rostaing, Natalie Ebert, Elke Schaeffner, Arend Bökenkamp, Christophe Mariat, Hans Pottel, Pierre Delanaye

“…Conclusions A strategy using machine learning model marginally improves the trustworthiness of GFR estimation at the population level. An additional value of this approach lies in its ability to provide assessments at the individual level.…”
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Efficacy and safety of anemoside B4 in canine pneumonia treatment: a prospective, randomized controlled trial by Jinzhao Ji, Jinzhao Ji, Xiaoqing Ding, Xiaoqing Ding, Chuanli Liu, Chuanli Liu, Lingling Dai, Lingling Dai, Junting Yu, Junting Yu, Linghao Li, Linghao Li, Shaobing Wan, Shaobing Wan, Yangyang Song, Junqing Zhao, Zhetong Su, Kun Jia, Kun Jia, Shoujun Li, Shoujun Li

“…The primary outcome was the effect of AB4 on comprehensive clinical scoring of canine pneumonia; secondary outcomes included recovery times for primary symptoms and efficacy assessments. Additionally, AB4′s safety in clinical applications was evaluated.ResultsThe AB4 group demonstrated significantly lower composite clinical scores on Days 7 and 14 compared to the placebo group (p = 0.033 and p = 0.000, respectively). …”
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Laparoscopic excision of deep rectovaginal endometriosis in BSGE endometriosis centres: a multicentre prospective cohort study by Paul Smith, Lucky Saraswat, Sanjay Vyas, Thomas Ind, Ertan Saridogan, Elizabeth Ball, Edward Morris, James Clark, Tony Chalhoub, David Rowlands, Moiad Alazzam, Dominic Byrne, Tamara Curnow, Alfred Cutner, T Justin Clark, Iris Menninger, Yousri Afifi, Kevin Phillips, Saikat Banerjee, Robert Richardson, Jeremy Hawe, Barry Whitlow, Emmanuel Ofuasia, Ashwini Trehan, Tyrone Carpenter, Christian Becker, Stuart Jack, Kumar Kunde, Chris Barnick, Alan Farthing, Graham Phillips, John Bidmead, Mohamed Abdel-aty, George Botros, Marlin Mubarak, Christian Kremer, Stanley Okolo, Edmond Edi-osagi, Kamel Shehata-iskander, Gaity Ahmad, Jonathan Frappell, Brice Rodriguez, Yemi Coker, Gourab Misra, Adam Moors, Chris Guyer, Caroline Overton, Suku George, Oliver Chappatte, Richard Penketh, Funlayo Odejinmi, Keith Louden, Jon Hughes

“…Serious perioperative and postoperative complications including major haemorrhage, infection and visceral injury were recorded.Results At 6 months postsurgery, there were significant reductions in premenstrual, menstrual and non-cyclical pelvic pain, deep dyspareunia, dyschezia, low back pain and bladder pain. In addition, there were significant reductions in voiding difficulty, bowel frequency, urgency, incomplete emptying, constipation and passing blood. …”
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Changes in Alcohol Consumption During and After the Covid-19 Pandemic From 2020 to 2023 in a Prospective Cohort of Italian Adults by Sonia Cerrai, Giulia Carreras, Filippo Monti, Chiara Stival, Alessandra Lugo, Cristina Bosetti, Silvia Biagioni, Tiziana Fanucchi, Giuseppe Gorini, Andrea Amerio, Luisa Mastrobattista, Claudia Mortali, Anna Odone, Sabrina Molinaro, Luc Smits, Silvano Gallus, the “Lost in Italy” and “Lost in Toscana” Study Investigators

“…Methods: LOckdown and lifeSTyles in Italy and in Tuscany studies collected data on a representative sample of the Italian adult population in 2020 (n = 6,003) followed up through 2023 via four additional surveys (3,000 ≤ n ≤ 6,600) through an online self-administered questionnaire. …”
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Adjuvant Therapy after Esophagectomy for Esophageal Cancer: Who Needs It?: Multi-institution Worldwide Observational Study by Siva Raja, MD, PhD, Thomas W. Rice, MD, Min Lu, PhD, Marie E. Semple, MPH, Andrew J. Toth, MS, Eugene H. Blackstone, MD, Sudish C. Murthy, MD, PhD, Usman Ahmad, MD, Michael McNamara, MD, Hemant Ishwaran, PhD, for the Worldwide Esophageal Cancer Collaboration Investigators

“…From 1970 to 2014, 22,123 consecutive patients from 33 centers on 6 continents (Worldwide Esophageal Cancer Collaboration) were diagnosed with biopsy-proven adenocarcinoma (n = 7526) or squamous cell carcinoma (n = 5625), of whom 10,873 received esophagectomy alone and 2278 additional adjuvant therapy. Random forests for survival and virtual-twin analyses were performed for all-cause mortality. …”
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Neuroendocrine Neoplasms of the Gallbladder: A Clinicopathological Analysis of 13 Patients and a Review of the Literature by Pengyan Wang, Jingci Chen, Ying Jiang, Congwei Jia, Junyi Pang, Shan Wang, Xiaoyan Chang

“…The clinical data and pathological features of 13 patients with GB-NENs in our hospital were retrospectively reviewed. Additionally, 41 GB-MiNENs cases reported in English literature were reviewed and survival analysis was performed. …”
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Weight loss for overweight and obese patients with prostate cancer: a study protocol of a randomised trial comparing clinic-based versus Telehealth delivered EXercise and nutrition... by Robert U Newton, Daniel A Galvão, Dennis R Taaffe, Suzanne K Chambers, David Joseph, Amanda Devine, Colin I Tang, Nigel Spry, Emily Jeffery, Dickon Hayne, Pedro Lopez, P Lyons-Wall, Christine Kudiarasu

“…Exercise will consist of supervised resistance and aerobic exercise performed three times a week plus additional self-directed aerobic exercise performed 4 days/week for the first 6 months. …”
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miRNAs and Hematological Markers in Non-Alcoholic Fatty Liver Disease—A New Diagnostic Path? by Agata Michalak, Małgorzata Guz, Joanna Kozicka, Marek Cybulski, Witold Jeleniewicz, Ilona Telejko, Karolina Szczygieł, Ewa Tywanek, Halina Cichoż-Lach

“…The assessment of hematological parameters concerned: mean platelet volume (MPV), platelet distribution width (PDW), plateletcrit (PCT), red blood cell distribution width (RDW), MPV to platelet (PLT) ratio (MPR), RDW to PLT ratio (RPR), neutrophil to lymphocyte (LYM) ratio (NLR), PLT to LYM ratio (PLR) and RDW to LYM ratio (RLR). Additionally, the NAFLD fibrosis score and BARD score were applied. …”
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Infection‐Related Hospitalization and Incident Heart Failure: The Atherosclerosis Risk in Communities Study by Rebecca L. Molinsky, Amil Shah, Melana Yuzefpolskaya, Bing Yu, Jeffrey R. Misialek, Bruno Bohn, David Vock, Richard MacLehose, Barry A. Borlaug, Paolo C. Colombo, Chiadi E. Ndumele, Junichi Ishigami, Kunihiro Matsushita, Pamela L. Lutsey, Ryan T. Demmer

“…Additionally, IRH was associated with both HF with reduced ejection fraction and HF with preserved ejection fraction: 1.77 (95% CI, 1.35–2.32) and 2.97 (95% CI, 2.36–3.75), respectively. …”
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Evaluation of the Effects of Degradable Mulching Film on the Growth, Yield and Economic Benefit of Garlic by Jiangping Song, Huixia Jia, Yang Wang, Xiaohui Zhang, Wenlong Yang, Tingting Zhang, Naijian Wang, Jianqiang Yang, Haiping Wang

“…The quality characteristics of garlic bulbs, including the contents of soluble sugar, vitamin C, and allicin, did not differ significantly between PEM and BDMs. …”
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The association between systemic inflammatory response index and contrast-associated acute kidney injury in patients undergoing elective percutaneous coronary intervention by Jun-Han Chen, Li-Wei Zhang, Wen-Jia Liang, Wei-ze Lin, Xiao-Fang Chen, Zhi-Jie Lin, Chang-Xi Wang, Kai-Yang Lin, Yan-Song Guo

“…Additionally, COX regression analysis showed that SIRI > 1.39 was significantly associated with long-term mortality at a median follow-up of 2.8 years. …”
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Beyond variance: simple random distributions are not a good proxy for intraspecific variability in systems with environmental structure by Girard-Tercieux, Camille, Vieilledent, Ghislain, Clark, Adam, Clark, James S., Courbaud, Benoit, Fortunel, Claire, Kunstler, Georges, Pélissier, Raphaël, Rüger, Nadja, Maréchaux, Isabelle

“…This highlights that incorporating unstructured IV (i.e. a random noise) to account for unexplained (but structured) variation can lead to incorrect simulations of community dynamics. In addition, the effects of unstructured IV on community diversity and composition depended on the relative importance of structured vs unstructured IV, i.e. on the level of knowledge of the environment, which may partly explain the contrasting results of previous studies on the effect of IV on species coexistence. …”
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