Astrocytic NLRP3 cKO mitigates depression-like behaviors induced by mild TBI in mice. by Hui-Tao Miao, Jun Wang, Jing-Jing Shao, Rong-Xin Song, Wen-Guang Li, Jian-Kai Sun, Shi-Yan Jia, Dong-Xue Zhang, Xiao-Ming Li, Jian-Yong Zhao, Li-Min Zhang

“…It also led to the upregulation of protective astrocytes and apoptosis-associated factors, including cleaved caspase-3 post-mild TBI. Additionally, astrocyte-specific NLRP3 deletion resulting in improved θ and γ power and θ-γ phase coupling in the social interaction test (SI). …”
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Rusların 1915 Yılında Van Vilayeti ve Çevresinden Ermenileri Kafkasya’ya Göç Ettirmesi by Nejla GÜNAY, Güzin ÇAYKIRAN

“…Daha sonra Osmanlı ordusu mukabil bir harekâtla Rusların işgal ettiği bölgelerden Malazgirt, Adilcevaz ve Karaköse’yi geri aldı. Bunun üzerine Ruslar bölgede bazı kararlar aldılar. …”
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Effectiveness of a Novel Liposomal Methylglyoxal–Tobramycin Formulation in Reducing Biofilm Formation and Bacterial Adhesion by Wed Alluhaim, Manal M. Alkhulaifi, Raghad R. Alzahrani, Bahauddeen M. Alrfaei, Alaa Eldeen B. Yassin, Majed F. Alghoribi, Ahlam M. Alsaadi, Ahmed I. Al-Asmari, Ahmed J. Al-Fahad, Rizwan Ali, Naif M. Alhawiti, Majed A. Halwani

“…<b>Conclusions:</b> The Lip-MGO-TOB formulation significantly enhanced TOB activity against resistant bacteria compared to free TOB. Additionally, it provided a stable drug delivery system with controlled drug release. …”
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Prostate cancer cells elevate glycolysis and G6PD in response to caffeic acid phenethyl ester-induced growth inhibition by Tzu-Ping Lin, Pei-Chun Chen, Ching-Yu Lin, Bi-Juan Wang, Ying-Yu Kuo, Chien-Chih Yeh, Jen-Chih Tseng, Chieh Huo, Cheng-Li Kao, Li-Jane Shih, Jen-Kun Chen, Chia-Yang Li, Tzyh-Chyuan Hour, Chih-Pin Chuu

“…Co-treatment of AMPK inhibitor with CAPE exhibited additive growth inhibition on PCa cells. Conclusions Our study indicated that PCa cells attempted to overcome the CAPE-induced stress by upregulation of glycolysis and G6PD but failed to impede the growth inhibition caused by CAPE. …”
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Bisphenol A attenuates testosterone synthesis via increasing apolipoprotein A1-mediated reverse cholesterol transport in mice by Tong Zhao, Tong Zhao, Wenzhe Yang, Wenzhe Yang, Feilong Pan, Feilong Pan, Jinhao Wang, Jinhao Wang, Wenqi Shao, Wenqi Shao, Fangfang Chen, Fangfang Chen, Kexiang Liu, Kexiang Liu, Shuchen Zhao, Shuchen Zhao, Lijia Zhao, Lijia Zhao

“…Notably, BPA significantly upregulated Apoa1 mRNA and protein level, reduced cholesterol levels and lipid droplets accumulation, and attenuated testosterone synthesis in TM3 cells. In addition, exogenous supplement with 22-hydoxycholesterol promoted testosterone synthesis and alleviated the inhibitory effect of BPA on testosterone synthesis. …”
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Nomogram to screen older adult patients attending the radiology department for sarcopenia by Guiying Yuan, Guoxi Ye, Jianguang Hu, Huimin Hu, Chanmei Shi, Ye Zhang, Junbing Huang, Zhiqiong Li, Xuwen Zeng, Rongshao Tan, Yuchao Xiong

“…The discriminative ability of these parameters for sarcopenia was assessed using receiver operating characteristic analysis. Additionally, we included each screening parameter and evaluated it’s important for screening for the presence of sarcopenia via univariate and multivariate logistic regression analysis to develop a new screening nomogram model. …”
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Key Decision‐Making in Post‐Failed Internal Fixation of Intertrochanteric Fractures Hip Arthroplasty: A Multicenter Retrospective Study on Fracture Healing's Impact on Femoral Comp... by Jiexin Huang, Jiagu Huang, Haiqi Ding, Jianhua Lyu, Changyu Huang, Yang Chen, Qijin Wang, Hongyan Li, Baijian Wu, Ying Huang, Minghui Yang, Xinyu Fang, Wenming Zhang

“…Statistical analysis included binary and ordinal logistic regression to identify factors influencing the choice of femoral stems. Additionally, a decision tree model was developed to visually represent and explore the relationship between fracture healing status and the selection of femoral components. …”
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Modifiable Risk Factors Including Self-Perceived Stress for Breast Cancer in Hong Kong: A Case-Control Study of 10 757 Subject by Winnie Yeo, Lok-Wa Yuen, Kelvin Kam-Fai Tsoi, Emily Ying-Yang Chan, Carol C Kwok, Inda Soong, Ting-Ying Ng, Joanne Chiu, Miranda Chan, Sharon Wing-Wai Chan, Ting-Ting Wong, Yolanda Ho-Yan Chan, Lawrence Pui-Ki Li, Chun-Chung Yau, Wai-Ka Hung, Polly Suk-Yee Cheung

“…Background: In Hong Kong, breast cancer is the commonest female cancer. In addition to intrinsic risk factors that cannot be modified, other factors may be potentially modifiable. …”
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Electrophysiological and Structural Changes in Chinese Patients with LHON by Min Wang, Hong Guo, Shiying Li, Gang Wang, Yanling Long, Xiaohong Meng, Bo Liu, Yong Liu, Anthony G. Robson, Zheng Qin Yin

“…There is PERG evidence of retinal ganglion cell dysfunction and OCT evidence of GCL + IPL thinning in both groups, but there is additional peripapillary RNFL loss in the chronic stage, associated with more severe RGC dysfunction. …”
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Chitosan-multilayered graphene oxide hybrid beads for $\protect \text{Zn}^{2+}$ and metoprolol adsorption by Bouyahmed, Farida, Muller, Fabrice, Richard, Annie, Mostefaoui, Toufik Amayas, Belabbas, Imad, Warmont, Fabienne, Roulet, Marjorie, Reinert, Laurence, Duclaux, Laurent, Delpeux-Ouldriane, Sandrine

“…The hybrid beads were prepared by gelation in NaOH solution of a 1 wt% CS acid solution with addition of MGO at either 1.5 wt% or 3 wt% loading rates. …”
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The promotion effect of FeS2 on Sb2S3 bioleaching and Sb speciation transformation by Xing-fu Zheng, Xing-fu Zheng, Xing-fu Zheng, Jin-lan Xia, Jin-lan Xia, Zhen-yuan Nie, Zhen-yuan Nie, Hong-peng Cao, Hong-peng Cao, Rui-Jia Hu, Yu-ting Liang, Hong-chang Liu, Hong-chang Liu

“…The DFT results show that between the Sb2S3 (0 1 0) and FeS2 (1 0 0) surfaces, S-Fe, S-S, S-Sb, and Sb-Fe bonds are formed, and the direction of electron transfer is from Sb2S3 to FeS2; the work functions for Sb2S3 after addition of FeS2 decrease, implying that faster electron transfer occurs; Fe(III)-6H2O derived from FeS2 adsorbs on the surface more easily than does glucose, which is the major component of the extracellular polymeric substances in bacteria, indicating that during the bioleaching process, Fe(III)-6H2O plays an important role; after mixing, both Fe(III)-6H2O and glucose adsorb on the Sb2S3 (0 1 0) surface more easily, with stronger bonds and larger adsorption energies, which are in good agreement with the experimental results.…”
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Recombinant Lactococcus lactis Carrying IL-4 and IL-10 Coding Vectors Protects against Type 1 Diabetes in NOD Mice and Attenuates Insulitis in the STZ-Induced Model by Tatiane M. Preisser, Vanessa P. da Cunha, Mariana P. Santana, Vanessa B. Pereira, Denise C. Cara, Bianca M. Souza, Anderson Miyoshi

“…It was shown that the combined treatment with recombinant bacterial by oral route prevented hyperglycemia and reduced the pancreatic islets-destruction in NOD mice. In addition, increased levels of IL-4 and IL-10 in serum and pancreatic tissue revealed a systemic effect of the treatment and also favored an anti-inflammatory microenvironment. …”
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Multi-omics unveils strain-specific neuroactive metabolite production linked to inflammation modulation by Bacteroides and their extracellular vesicles by Basit Yousuf, Walid Mottawea, Galal Ali Esmail, Nazila Nazemof, Nour Elhouda Bouhlel, Emmanuel Njoku, Yingxi Li, Xu Zhang, Zoran Minic, Riadh Hammami

“…Using untargeted and targeted metabolomics, we identified key neurotransmitter-related or precursor metabolites, including GABA, l-tryptophan, 5-HTP, normelatonin, kynurenic acid, l-tyrosine, and norepinephrine, in a strain- and media-specific manner, with GABA (1–2 mM) being the most abundant. Additionally, extracellular vesicles (EVs) produced by Bacteroides harbor multiple neuroactive metabolites, mainly GABA, and related key enzymes. …”
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The Association of Cell-Free LncH19 and miR-29b Expression with the PI3K/AKT/HIF-1/VEGF Pathway in Patients with Diabetic Nephropathy: In Silico Prediction and Clinical Validation by Noha M. Abd El-Fadeal, Basma Osman Sultan, Asmaa K. K. AbdelMaogood, Essam Al Ageeli, Fatma Tohamy Mekhamer, Sherihan Rohayem, Ahmed Shahidy, Nora Hosny, Manal S. Fawzy, Mohammed M. Ismail, Hidi A. A. Abdellatif

“…Non-coding RNAs (ncRNAs) represent a new frontier in DN research, as increasing evidence suggests their involvement in the occurrence and progression of DN. A growing body of evidence suggests that long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) in DN signaling pathways might serve as novel biomarkers or therapeutic targets, although this remains to be fully explored. …”
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C1q/TNF-Related Protein5 (CTRP5) as a Biomarker to Predict Metabolic Syndrome and Each of Its Components by Feiyu Jiang, Min Yang, Xili Zhao, Rui Liu, Gangyi Yang, Dongfang Liu, Hua Liu, Hongting Zheng, Zhiming Zhu, Ling Li

“…Binary logistic regression revealed that serum CTRP5 levels were associated with MetS. In addition, serum CTRP5 levels gradually decreased with the increase in MetS components. …”
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Clinical Rehabilitation Effect of Postoperative Lower-Limb Training on the Patients Undergoing OLIF Surgery: A Retrospective Study by Haoming Wang, Yachong Huo, Yachao Zhao, Botong Zhang, Dalong Yang, Sidong Yang, Wenyuan Ding

“…No statistical significance between the two groups was found (P>0.05). ODI score was less in the intervention group as compared to the control group in the first week after surgery (P=0.029). …”
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Stem Cells from Human Exfoliated Deciduous Teeth Ameliorate Diabetic Nephropathy In Vivo and In Vitro by Inhibiting Advanced Glycation End Product-Activated Epithelial-Mesenchymal... by Nanquan Rao, Xiaotong Wang, Jing Xie, Jingzhi Li, Yue Zhai, Xiaoxia Li, Tengjiaozi Fang, Yuanyuan Wang, Yuming Zhao, Lihong Ge

“…Blood glucose, serum triglycerides and cholesterol, body weight, and urinary albumin were measured before and after administration. …”
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Gender differences of health literacy in persons with a migration background: a systematic review and meta-analysis by Elke Kalbe, Nicole Skoetz, Christiane Woopen, Digo Chakraverty, Annika Baumeister, Angela Aldin, Ümran Sema Seven, Ina Monsef

“…In six studies, gender-specific health literacy scores were reported. The authors of additional 15 studies provided their data upon request and for one further study data were available online. …”
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Prevalence, risk factors, and prognostic implications of intraoperative bleeding during CF-LVAD implant by Ibrahim Mortada, MD, Christos Kourek, MD, PhD, Rupesh Kshetri, MD, Arun Singhal, MD, Anthony Panos, MD, Alexandros Briasoulis, MD, PhD, Mohammed Mhanna, MD, MPH, Shareef Mansour, MD, Kristine Yumul, MD, Paulino Alvarez, MD, Ernesto Ruiz Duque, MD

“…Intraoperative bleeding occurred in 43 (20.67%) patients while 165 (79.33%) patients did not experience bleeding. Multilogistic regression analysis showed that artery bypass grafting pre-LVAD (odds ratio [OR] 2.98, confidence interval [CI] 1.2-7.42, p = 0.01) and temporary mechanical assist device pre-LVAD (OR 3.67, 95%CI 1.72-7.85, p < 0.001) were independent predictors of intraoperative bleeding during hospitalization. …”
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Assessment of Different Conventional and Biofortified Wheat Genotypes Based on Biology and Damage Pattern of <i>Rhyzopertha dominica</i> and <i>Trogoderma granarium</i> by Hafiz Muhammad Bilal Yousuf, Muhammad Yasin, Muhammad Asif Khan, Asim Abbasi, Muhammad Arshad, Muhammad Anjum Aqueel, Inzamam Ul Haq, Waleed A. A. Alsakkaf, Marwa I. Mackled, Nazih Y. Rebouh, Hayssam M. Ali

“…Similarly, percent grain damage (13.23 and 10.33%) and weight loss (3.62 and 2.12%) were found to be minimum in Akbar-2019 for both pest species, respectively. Additionally, a positive correlation was observed between grain moisture content and damage parameters, suggesting that the higher moisture content may aggravate the percent grain damage and weight loss. …”
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