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53101
Distinctive dust weather intensities in North China resulted from two types of atmospheric circulation anomalies
Published 2025-02-01“…Previous research has primarily focused on the role of the Mongolian cyclone in influencing dust weather in NC, with less attention given to other synoptic systems. Additionally, the differences in PM<span class="inline-formula"><sub>10</sub></span> concentrations in NC caused by different synoptic systems have not yet been quantified. …”
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53102
Addressing challenges in pediatric thrombosis: a comprehensive guideline development
Published 2025-01-01“…Recent studies have indicated a rising incidence of this disease in children over the years. Additionally, the pharmacological treatment of thrombotic diseases in children faces numerous challenges. …”
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53103
Mannan-Binding Lectin Suppresses Peptidoglycan-Induced TLR2 Activation and Inflammatory Responses
Published 2019-01-01“…Administration of MBL alone did not have an effect on the expression of TLR2. …”
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53104
Applied machine learning for predicting the properties and carbon and phosphorus fate of pristine and engineered hydrochar
Published 2025-01-01“…FeCl3 impregnation increased Fe-phosphate content, while it reduced H/C and O/C ratios and hydroxyapatite P content, and therefore improved C stability and P availability in the HC-Fe as compared to HC, particularly under lower pH (4), temperature of 220 ℃, and at 120 min. The generalized additive ML model outperformed the other models for predicting the HC properties with a correlation coefficient of 0.86. …”
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53105
Experimental Validation of Antiobesogenic and Osteoprotective Efficacy of Ginsenoside CK via Targeting Lipid and Atherosclerosis Pathways
Published 2024-12-01“…Using 3T3-L1 adipocytes in vitro assessments, CK could effectively decrease intracellular lipid accumulation, inhibit α-glucosidase enzyme, increase 2-NBDG glucose uptake, reduce inflammation-associated cytokines (<i>TNFα</i>, and <i>IL-6</i>), adipogenic regulatory genes (<i>PPARγ</i>, <i>FAS</i>, <i>C/EBPα</i>), lipogenic gene <i>LPL</i>, and increase the expression of thermogenic gene <i>UCP1</i>. Additionally, CK treatment induced osteoblast development in MC3T3-E1 cells as shown by increased mineralization and calcium distribution, collagen content, alkaline phosphatase activity, and decreased inflammatory cytokines <i>TNFα</i>, and <i>IL-6</i> and increased the regulated expressions of osteogenic genes including <i>Runx2</i>, <i>ALP</i>, <i>BGLAP</i>, <i>OCN</i>, and <i>Col1a1</i>. …”
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53106
Thulium laser enucleation of the prostate plus thulium fiber laser therapy for benign prostatic hyperplasia combined with bladder stones
Published 2024-08-01“…Results: The patients in the observation group exhibited lower surgery duration, smaller postoperative decrease in Hb levels, shorter duration of postoperative indwelling catheterization, and proportion of American Society of Anesthesiologists (ASA) II patients, with a higher proportion of ASA I patients than the individuals in the control group (P <0.05). Additionally, in comparison with the control group, the patients in the observation group had lower postoperative IPSS scores and higher levels of Hb, Qmax, and QoL score (P <0.05). …”
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53107
Association between ethylene oxide exposure and osteoarthritis risk: an analysis of NHANES data (2013–2014 and 2017–2018)
Published 2025-01-01“…In multivariate logistic regression, high EO level exposure was significantly associated with increased OA risk. Additionally, a nonlinear U-shaped and J-shaped association was observed in the unadjusted and adjusted RCS models, respectively. …”
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53108
SPIRIT-DEFINE explanation and elaboration: recommendations for enhancing quality and impact of early phase dose-finding clinical trials protocolsResearch in context
Published 2025-01-01“…The principal investigator (CY) used internal staff resources, together with additional resources from external partners, to conduct this study. …”
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53109
Synergistic photothermal conversion and visible-light photodegradation of antibiotic in S-type TiO2 derived Ti3C2-MXene loaded on NaYF4: Tm3+, Er3+, Yb3+ @BiOI
Published 2025-06-01“…It can be attributed to the synergistic photocatalytic and photothermal effects triggered by NIR light. In addition, the broad photoresponse range of TiO2 and the Schottky junction formed by Ti3C2 MXenes between TiO2 and BiOI facilitate charge separation while reducing photo-generated electron-hole pair recombination. …”
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53110
Knowledge, attitudes and practices of intensive care unit physicians towards the management of acute respiratory distress syndrome in China: a cross-sectional survey
Published 2025-01-01“…Pearson correlation analysis showed positive correlations between knowledge and attitude (0.367), knowledge and practice (0.582) and attitude and practice (0.314) (all p<0.001).Results Mediation analysis indicated that attitude (β=0.07, p<0.001) and hospital type (β=−0.84, p=0.005) had direct effects on practice, while knowledge had significant direct (β=0.68, p<0.001) and indirect (β=0.03, p=0.019) effects. Additionally, education (β=0.47, p<0.001), work experience (β=0.25, p<0.001), hospital classification (β=−0.91, p<0.001), ICU type (β=−0.61, p=0.001) and ARDS experience (β=−1.57, p<0.001) showed various indirect effects on practice.Conclusions ICU physicians in China exhibited inadequate knowledge, moderate attitudes and suboptimal practices regarding ARDS management. …”
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53111
Effect of Eight-Week Transcranial Direct-Current Stimulation Combined with Lat Pull-Down Resistance Training on Improving Pull-Up Performance for Male College Students
Published 2025-01-01“…Both groups demonstrated significant improvements in pull-up endurance and lat pull-down MVIC peak force after training, but no significant difference between the two groups was observed in the post-training test. Additionally, muscle activation of BR, PD, and PM decreased significantly in both groups, while the RT + tDCS group also demonstrated a significant reduction in TB coactivation after training. …”
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53112
Fusion protein-based COVID-19 vaccines exemplified by a chimeric vaccine based on a single fusion protein (W-PreS-O)
Published 2025-01-01“…Neutralizing antibody (nAB) titers, weight, lung symptoms, and viral loads, as measured using RT-PCR in the upper and lower respiratory tracts, were determined. In addition, infectious virus titers from the lungs were measured using a plaque-forming assay. …”
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53113
Advancements in noninvasive techniques for transplant rejection: from biomarker detection to molecular imaging
Published 2025-02-01“…Additionally, microRNA (miRNA) profiling enhances the diagnostic specificity for precise AR detection. …”
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53114
Little Red Dots: Rapidly Growing Black Holes Reddened by Extended Dusty Flows
Published 2025-01-01“…There is no need for additional stellar emission or AGN scattered light. …”
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53115
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53116
Efficacy of yeast beta-glucan 1,3/1,6 supplementation on respiratory infection, fatigue, immune markers and gut health among moderate stress adults in Klang Valley of Malaysia: pro...
Published 2025-01-01“…The outcomes measures include respiratory infection symptoms, fatigue, mood state and quality of life assessed using Wisconsin Upper Respiratory Symptoms Scale, Multidimensional Fatigue Inventory, Profile of Mood State and Short Form 36 Health Survey Questionnaire, respectively. In addition, full blood analysis and assessment of immune, inflammatory and oxidative stress biomarkers will be taken. …”
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53117
Pan-cancer and experimental analyses reveal the immunotherapeutic significance of CST2 and its association with stomach adenocarcinoma proliferation and metastasis
Published 2025-01-01“…These factors include prognosis, immune cell infiltration, immune-related genes, mutations, methylation, tumor mutation burden (TMB), and microsatellite instability (MSI). In addition, we analyzed the sensitivity of drugs dependent on CST2 expression. …”
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53118
Alpha and Theta Oscillations Associated With Behavioral Phenotypes of Pain–Attention Interaction
Published 2025-01-01“…ABSTRACT Purpose Pain is inherently salient and so draws our attention in addition to impacting performance on attention‐demanding tasks. …”
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53119
Treating common mental disorder including psychotic experiences in the primary care improving access to psychological therapies programme (the TYPPEX study): protocol for a stepped...
Published 2022-06-01“…Introduction At least one in four people treated by the primary care improving access to psychological therapies (IAPT) programme in England experiences distressing psychotic experiences (PE) in addition to common mental disorder (CMD). These individuals are less likely to achieve recovery. …”
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53120
Prenatal exposure to a mixture of organophosphate ester and organophosphorus pesticides in relation to child neurodevelopment in the Shanghai Birth Cohort
Published 2025-01-01“…Additional research is required to validate our findings and elucidate the underlying mechanisms.…”
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